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List of works by Xi Chen

3'-Terminal 2'-O-methylation of lung cancer miR-21-5p enhances its stability and association with Argonaute 2

scientific article published on 15 June 2020

A Five-miRNA Panel Identified From a Multicentric Case-control Study Serves as a Novel Diagnostic Tool for Ethnically Diverse Non-small-cell Lung Cancer Patients

scientific article

A Microarray-based Approach Identifies ADP Ribosylation Factor-like Protein 2 as a Target of microRNA-16

scientific article published on January 3, 2011

A Novel Role for MiR-520a-3p in Regulating EGFR Expression in Colorectal Cancer

scientific article published on 24 July 2017

A combination of Let-7d, Let-7g and Let-7i serves as a stable reference for normalization of serum microRNAs

scientific article

A five-microRNA signature identified from genome-wide serum microRNA expression profiling serves as a fingerprint for gastric cancer diagnosis

scientific article published on November 26, 2010

A panel of five serum miRNAs as a potential diagnostic tool for early-stage renal cell carcinoma

scientific article published on 05 January 2015

A panel of four decreased serum microRNAs as a novel biomarker for early Parkinson's disease

scientific article published on 3 December 2015

A panel of microRNAs as a new biomarkers for the detection of deep vein thrombosis

scientific article published on 01 February 2015

A panel of serum microRNAs as specific biomarkers for diagnosis of compound- and herb-induced liver injury in rats

scientific article

A universal activator of microRNAs identified from photoreaction products

scientific article published on 21 May 2012

A virus-derived microRNA-like small RNA serves as a serum biomarker to prioritize the COVID-19 patients at high risk of developing severe disease

scientific article

Absorbed plant MIR2911 in honeysuckle decoction inhibits SARS-CoV-2 replication and accelerates the negative conversion of infected patients

scientific article published on 05 August 2020

Altered Profile of Seminal Plasma MicroRNAs in the Molecular Diagnosis of Male Infertility

scientific article published on September 20, 2011

Altered Serum MicroRNA Profile May Serve as an Auxiliary Tool for Discriminating Aggressive Thyroid Carcinoma from Nonaggressive Thyroid Cancer and Benign Thyroid Nodules

scientific article published on 16 September 2019

Altered profile of serum microRNAs in pancreatic cancer-associated new-onset diabetes mellitus

scientific article published on 15 September 2015

An Ebola virus-encoded microRNA-like fragment serves as a biomarker for early diagnosis of Ebola virus disease

scientific article published on 23 February 2016

An efficient vector for gene delivery: alpha,beta-poly (3-dimethylaminopropyl-D,L-aspartamide)

scientific article published on 01 December 2006

Argonaute 2 complexes selectively protect the circulating microRNAs in cell-secreted microvesicles

scientific article

BAP1 suppresses lung cancer progression and is inhibited by miR-31

scientific article published on 11 February 2016

Baicalin, the major component of traditional Chinese medicine Scutellaria baicalensis induces colon cancer cell apoptosis through inhibition of oncomiRNAs

scientific article published in Scientific Reports

Bletilla striata polysaccharide stimulates inducible nitric oxide synthase and proinflammatory cytokine expression in macrophages.

scientific article

Cell-free miR-24 and miR-30d, potential diagnostic biomarkers in malignant effusions

scientific article published on November 18, 2010

Cell-free miRNAs may indicate diagnosis and docetaxel sensitivity of tumor cells in malignant effusions

scientific article published on October 28, 2010

Characterization of a novel panel of plasma microRNAs that discriminates between Mycobacterium tuberculosis infection and healthy individuals

scientific article published on 14 September 2017

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

scientific article (publication date: October 2008)

Circular RNA FAM114A2 suppresses progression of bladder cancer via regulating ∆NP63 by sponging miR-762

scientific article published on 22 January 2020

Comparison of commercial exosome isolation kits for circulating exosomal microRNA profiling

scientific article published on 18 April 2018

Correction: miR-135b Promotes Cancer Progression by Targeting Transforming Growth Factor Beta Receptor II (TGFBR2) in Colorectal Cancer

scientific article published on 17 December 2015

Decreased HD-MIR2911 absorption in human subjects with the SIDT1 polymorphism fails to inhibit SARS-CoV-2 replication

scientific article published on 11 September 2020

Deregulation of the miR-16-KRAS axis promotes colorectal cancer

scientific article

Diagnostic and prognostic implications of a serum miRNA panel in oesophageal squamous cell carcinoma

scientific article

Differential expression of microRNAs in mouse liver under aberrant energy metabolic status

scientific article published on 16 April 2009

Diphthamide Biosynthesis 1 is a Novel Oncogene in Colorectal Cancer Cells and is Regulated by MiR-218-5p

scientific article published on 17 November 2017

Direct quantification of 3' terminal 2'-O-methylation of small RNAs by RT-qPCR

scientific article published on 03 August 2018

Effective detection and quantification of dietetically absorbed plant microRNAs in human plasma.

scientific article published on 29 January 2015

Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA

scientific article

Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA.

scientific article published on 8 November 2011

Exosome-mediated small RNA delivery for gene therapy

scientific article

Expression Profile of MicroRNAs in Serum: A Fingerprint for Esophageal Squamous Cell Carcinoma

scientific article published on October 13, 2010

Expression of serum miR-16, let-7f, and miR-21 in patients with hepatocellular carcinoma and their clinical significances.

scientific article published in January 2014

H5N1 influenza virus-specific miRNA-like small RNA increases cytokine production and mouse mortality via targeting poly(rC)-binding protein 2.

scientific article published on 12 January 2018

HIC1 and miR-23~27~24 clusters form a double-negative feedback loop in breast cancer

scientific article published on 23 December 2016

Hepatitis B virus-human chimeric transcript HBx-LINE1 promotes hepatic injury via sequestering cellular microRNA-122.

scientific article published on 23 September 2015

Heterochromatin protein HP1γ promotes colorectal cancer progression and is regulated by miR-30a.

scientific article published on 2 September 2015

Honeysuckle-encoded atypical microRNA2911 directly targets influenza A viruses

scientific article

Horizontal transfer of microRNAs: molecular mechanisms and clinical applications

scientific article published on February 9, 2012

Hypoxia-induced miR-214 expression promotes tumour cell proliferation and migration by enhancing the Warburg effect in gastric carcinoma cells

scientific article published on 9 November 2017

ING5 suppresses breast cancer progression and is regulated by miR-24

scientific article

Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products

scientific article published on 15 June 2010

Identification and characterization of novel amphioxus microRNAs by Solexa sequencing

scientific article

Identification of Ebola virus microRNAs and their putative pathological function

scientific article published on 29 September 2014

Identification of a panel of five serum miRNAs as a biomarker for Parkinson's disease

scientific article published on 21 November 2015

Identification of miRNAs that are associated with tumor metastasis in neuroblastoma

scientific article published on 8 March 2010

Identification of mouse liver mitochondria-associated miRNAs and their potential biological functions

scientific article published on August 24, 2010

Identification of serum microRNAs for cardiovascular risk stratification in dyslipidemia subjects.

scientific article

Identification of seven serum microRNAs from a genome‐wide serum microRNA expression profile as potential noninvasive biomarkers for malignant astrocytomas

scientific article published on June 26, 2012

Identification of ten serum microRNAs from a genome-wide serum microRNA expression profile as novel noninvasive biomarkers for nonsmall cell lung cancer diagnosis

scientific article published on 03 August 2011

Immune modulatory function of abundant immune-related microRNAs in microvesicles from bovine colostrum

scientific article published on March 13, 2013

In vitro evidence suggests that miR-133a-mediated regulation of uncoupling protein 2 (UCP2) is an indispensable step in myogenic differentiation

scientific article

Increased Serum and Urinary MicroRNAs in Children with Idiopathic Nephrotic Syndrome

scientific article published on January 23, 2013

Injured liver-released miRNA-122 elicits acute pulmonary inflammation via activating alveolar macrophage TLR7 signaling pathway

scientific article published on 13 March 2019

Knockdown long noncoding RNA nuclear paraspeckle assembly transcript 1 suppresses colorectal cancer through modulating miR-193a-3p/KRAS

Let-7f-5p suppresses Th17 differentiation via targeting STAT3 in multiple sclerosis

scientific article published on 01 July 2019

MEG2 is regulated by miR-181a-5p and functions as a tumour suppressor gene to suppress the proliferation and migration of gastric cancer cells

scientific article published on 26 July 2017

MiR-125a-5p functions as a tumour suppressor in breast cancer by downregulating BAP1

scientific article published on 04 August 2018

MiR-143 and MiR-145 regulate IGF1R to suppress cell proliferation in colorectal cancer

scientific article

MiR-193a-3p is an Important Tumour Suppressor in Lung Cancer and Directly Targets KRAS.

scientific article published on 29 November 2017

MiR-19b suppresses PTPRG to promote breast tumorigenesis

scientific article published on September 2016

MiR-29b suppresses the proliferation and migration of osteosarcoma cells by targeting CDK6.

scientific article published on 26 May 2016

MiRNA-203 suppresses tumor cell proliferation, migration and invasion by targeting Slug in gastric cancer

scientific article published on 22 March 2016

MicroRNA-148a Suppresses the Proliferation and Migration of Pancreatic Cancer Cells by Down-regulating ErbB3.

scientific article published in October 2016

MicroRNA-181a promotes angiogenesis in colorectal cancer by targeting SRCIN1 to promote the SRC/VEGF signaling pathway.

scientific article

MicroRNA-193a-3p Reduces Intestinal Inflammation in Response to Microbiota via Down-regulation of Colonic PepT1

scientific article published on 30 April 2015

MicroRNA-223 delivered by platelet-derived microvesicles promotes lung cancer cell invasion via targeting tumor suppressor EPB41L3.

scientific article

MicroRNA-30a Sensitizes Tumor Cells to cis-Platinum via Suppressing Beclin 1-mediated Autophagy

scientific article published on December 8, 2011

MicroRNA-31 Activates the RAS Pathway and Functions as an Oncogenic MicroRNA in Human Colorectal Cancer by Repressing RAS p21 GTPase Activating Protein 1 (RASA1)

scientific article published on January 15, 2013

MicroRNA-495 induces breast cancer cell migration by targeting JAM-A.

scientific article

Microvesicle-mediated transfer of microRNA-150 from monocytes to endothelial cells promotes angiogenesis

scientific article published on 13 June 2013

New roles for microRNAs in cross-species communication

scientific article published on January 30, 2013

Nuclear miR-122 directly regulates the biogenesis of cell survival oncomiR miR-21 at the posttranscriptional level

scientific article published on 14 December 2017

Nuclear microRNAs and their unconventional role in regulating non-coding RNAs

scientific article published on 13 April 2013

Oncogenic miR-19a and miR-19b co-regulate tumor suppressor MTUS1 to promote cell proliferation and migration in lung cancer

scientific article

PGC-1alpha inhibits oleic acid induced proliferation and migration of rat vascular smooth muscle cells

scientific article

PGC-1alpha is a key regulator of glucose-induced proliferation and migration in vascular smooth muscle cells

scientific journal article

PTP1B markedly promotes breast cancer progression and is regulated by miR-193a-3p

scientific article published on 26 December 2018

Plant microRNAs in larval food regulate honeybee caste development

scientific article published on 31 August 2017

Plant-derived RNAi therapeutics: A strategic inhibitor of HBsAg

scientific article published on 01 May 2019

Plasma Exosomal miRNA Expression Profile as Oxaliplatin-Based Chemoresistant Biomarkers in Colorectal Adenocarcinoma

scientific article published on 18 September 2020

Platelet-secreted microRNA-223 promotes endothelial cell apoptosis induced by advanced glycation end products via targeting the insulin-like growth factor 1 receptor.

scientific article published on 4 December 2013

Pyruvate kinase type M2 promotes tumour cell exosome release via phosphorylating synaptosome-associated protein 23

scientific article

RNA virus-encoded microRNAs: biogenesis, functions and perspectives on application

scientific article published on 12 October 2020

Regulation of mammalian gene expression by exogenous microRNAs

scientific article published on June 27, 2012

Reply to Dr. Witwer's letter to the editor

scientific article published on 24 September 2015

Reply to Fromm et al

scientific article published on 05 September 2018

Reply to Lack of detectable oral bioavailability of plant microRNAs after feeding in mice.

scientific article published in November 2013

SIDT1-dependent absorption in the stomach mediates host uptake of dietary and orally administered microRNAs

scientific article published on 17 August 2020

Salmonella produce microRNA-like RNA fragment Sal-1 in the infected cells to facilitate intracellular survival

scientific article

Secreted microRNAs from tumor cells can suppress immune function

scientific article

Secreted microRNAs: a new form of intercellular communication

scientific article published on January 17, 2012

Secreted monocytic miR-150 enhances targeted endothelial cell migration

scientific article published on 01 July 2010

Selective secretion of microRNA in CNS system

scientific article published on 3 April 2013

Seminal Plasma and Seminal Plasma Exosomes of Aged Male Mice Affect Early Embryo Implantation <i>via</i> Immunomodulation

scientific article published on 12 October 2021

Serum MicroRNA Profiles Serve as Novel Biomarkers for the Diagnosis of Alzheimer's Disease.

scientific article published on 20 May 2015

Serum miRNA expression profile as a prognostic biomarker of stage II/III colorectal adenocarcinoma

scientific article published on 7 August 2015

Serum microRNA Profiles Serve as Novel Biomarkers for Autoimmune Diseases

Serum microRNA expression profile as a biomarker in the diagnosis and prognosis of pancreatic cancer

scientific article published on 22 December 2011

Serum microRNA profiles serve as novel biomarkers for HBV infection and diagnosis of HBV-positive hepatocarcinoma

scientific article published on November 23, 2010

Serum microRNA profiling and breast cancer risk: the use of miR-484/191 as endogenous controls

scientific article

Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer.

scientific article published in March 2010

Similar Responses of Circulating MicroRNAs to Acute High-Intensity Interval Exercise and Vigorous-Intensity Continuous Exercise.

scientific article published on 18 March 2016

Small RNA existed in commercial reverse transcriptase: primary evidence of functional small RNAs

scientific article

Small molecule inhibitor of myogenic microRNAs leads to a discovery of miR-221/222-myoD-myomiRs regulatory pathway

scientific article

Systematic characterization of seminal plasma piRNAs as molecular biomarkers for male infertility.

scientific article published on 12 April 2016

Targeted exosome-mediated delivery of opioid receptor Mu siRNA for the treatment of morphine relapse

scientific article

The HIF-1A/miR-17-5p/PDCD4 axis contributes to the tumor growth and metastasis of gastric cancer

scientific article published on 10 April 2020

The Jun/miR-22/HuR regulatory axis contributes to tumourigenesis in colorectal cancer

scientific article published on 19 January 2018

The c-Myc/miR-27b-3p/ATG10 regulatory axis regulates chemoresistance in colorectal cancer

scientific article published on 12 January 2020

The heparan sulfate proteoglycan form of epithelial CD44v3 serves as a CD11b/CD18 counter-receptor during polymorphonuclear leukocyte transepithelial migration

scientific article published on 10 December 2008

The identification of novel targets of miR-16 and characterization of their biological functions in cancer cells

scientific article published on 14 August 2013

The origin, function, and diagnostic potential of extracellular microRNAs in human body fluids

scientific article

The potential atheroprotective role of plant MIR156a as a repressor of monocyte recruitment on inflamed human endothelial cells

scientific article published on 08 April 2018

The use of hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma

scientific article published on 8 March 2010

Time-course responses of circulating microRNAs to three resistance training protocols in healthy young men

scientific article

Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth

scientific article

Tumor-suppressive miR-218-5p inhibits cancer cell proliferation and migration via EGFR in non-small cell lung cancer

scientific journal article

Uncoupling protein-2 negatively regulates polymorphonuclear leukocytes chemotaxis via modulating [Ca2+] influx

scientific article published on 23 December 2009

[Down-regulative expression of microRNAs cluster in human colon tumorigenesis].

scientific article

miR-10a inhibits cell proliferation and promotes cell apoptosis by targeting BCL6 in diffuse large B-cell lymphoma

scientific article

miR-124-3p functions as a tumor suppressor in breast cancer by targeting CBL.

scientific article

miR-135b Promotes Cancer Progression by Targeting Transforming Growth Factor Beta Receptor II (TGFBR2) in Colorectal Cancer

scientific article published on 10 June 2015

miR-138-5p contributes to cell proliferation and invasion by targeting Survivin in bladder cancer cells

scientific article published on 15 December 2016

miR-143 and miR-145 synergistically regulate ERBB3 to suppress cell proliferation and invasion in breast cancer

scientific article

miR-150 promotes the proliferation and migration of lung cancer cells by targeting SRC kinase signalling inhibitor 1.

scientific article published on 20 January 2014

miR-16 promotes the apoptosis of human cancer cells by targeting FEAT

scientific article published on 2 June 2015

miR-181b functions as an oncomiR in colorectal cancer by targeting PDCD4

scientific article published on 19 September 2016

miR-193a-3p functions as a tumor suppressor in lung cancer by down-regulating ERBB4.

scientific article

miR-19a promotes colorectal cancer proliferation and migration by targeting TIA1.

scientific article published on 04 March 2017

miR-19b downregulates intestinal SOCS3 to reduce intestinal inflammation in Crohn's disease

scientific article published on 22 May 2015

miR-203 enhances let-7 biogenesis by targeting LIN28B to suppress tumor growth in lung cancer

scientific article published on 20 February 2017

miR-203 inhibits cell proliferation and migration of lung cancer cells by targeting PKCα

scientific article

miR-203 suppresses the proliferation and migration and promotes the apoptosis of lung cancer cells by targeting SRC.

scientific article

miR-208a-3p suppresses cell apoptosis by targeting PDCD4 in gastric cancer

scientific article published on 13 September 2016

miR-23a/b promote tumor growth and suppress apoptosis by targeting PDCD4 in gastric cancer

scientific article published on 5 October 2017

miR-24-3p promotes colon cancer progression by targeting ING1

scientific article published on 25 August 2020

miR-338-3p functions as a tumor suppressor in gastric cancer by targeting PTP1B.

scientific article published in May 2018

miR-93 functions as an oncomiR for the downregulation of PDCD4 in gastric carcinoma

scientific article published on 29 March 2016

miR-96 promotes cell proliferation, migration and invasion by targeting PTPN9 in breast cancer

scientific article

miRNA regulates noncoding RNA: a noncanonical function model

scientific article published on 08 September 2012

miRNAs of Aedes aegypti (Linnaeus 1762) conserved in six orders of the class Insecta

scientific article published on 21 May 2021

microRNA-141 inhibits cell proliferation and invasion and promotes apoptosis by targeting hepatocyte nuclear factor-3β in hepatocellular carcinoma cells

scientific article

microRNA-200b and microRNA-200c promote colorectal cancer cell proliferation via targeting the reversion-inducing cysteine-rich protein with Kazal motifs

scientific article

microRNAs are ligands of Toll-like receptors

scientific article published on 03 April 2013

microRNAs in aged sperm confer psychiatric symptoms to offspring through causing the dysfunction of estradiol signaling in early embryos

scientific article published in 2022