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List of works by Lee A Denson

Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis

scientific article published in March 2019

Altered intestinal ACE2 levels are associated with inflammation, severe disease and response to anti-cytokine therapy in IBD

scientific article published on 02 November 2020

Analysis of Using the Total White Blood Cell Count to Define Severe New Onset Ulcerative Colitis in Children

scientific article published on 09 June 2020

Association Between Plasma Level of Collagen Type III alpha 1 Chain and Development of Strictures in Pediatric Patients With Crohn's Disease

scientific article published on 10 September 2018

Association of Baseline Luminal Narrowing With Ileal Microbial Shifts and Gene Expression Programs and Subsequent Transmural Healing in Pediatric Crohn Disease

scientific article published on 01 October 2021

Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation

scientific article published on 16 February 2019

Characterization of Stool Virome in Children Newly Diagnosed With Moderate to Severe Ulcerative Colitis

scientific article published on 01 September 2019

Clinical and Genomic Correlates of Neutrophil Reactive Oxygen Species Production in Pediatric Patients with Crohn's Disease

scientific article published on 15 February 2018

Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study

scientific article published on 29 March 2019

Common variants at five new loci associated with early-onset inflammatory bowel disease

scientific article

Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects

scientific article

Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course

article

Corrigendum. Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature

scientific article published on 2 March 2015

Dissecting Allele Architecture of Early Onset IBD Using High-Density Genotyping

scientific article published on 22 June 2015

Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease

scientific article

Enhanced Contribution of HLA in Pediatric Onset Ulcerative Colitis.

scientific article

Erratum: Corrigendum: Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scholarly article published in Nature Genetics

Factors associated with early outcomes following standardised therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study

scientific article published on 19 September 2017

Free and Bioavailable 25-Hydroxyvitamin D Concentrations are Associated With Disease Activity in Pediatric Patients With Newly Diagnosed Treatment Naïve Ulcerative Colitis.

scientific article published in February 2018

Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease

scientific article published on 01 February 2019

Genetic sharing and heritability of paediatric age of onset autoimmune diseases.

scientific article

Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohort.

scientific article published on 28 March 2018

Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease.

scientific article published on 28 September 2016

Granulocyte-macrophage colony-stimulating factor autoantibodies: a marker of aggressive Crohn's disease

scientific article published on July 2013

Histologic Correlates of Clinical and Endoscopic Severity in Children Newly Diagnosed With Ulcerative Colitis.

scientific article published on 31 August 2017

Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease

scientific article

Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease

scientific article

Long ncRNA Landscape in the Ileum of Treatment-Naive Early-Onset Crohn Disease.

scientific article published in January 2018

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scientific journal article

Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases

scientific article

Microbiota-derived metabolite promotes HDAC3 activity in the gut

scientific article published on 30 July 2020

Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease

Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-Only Crohn's Disease in Treatment-Naive Pediatric Patients

scientific article

Mucosal Inflammatory and Wound Healing Gene Programs Reveal Targets for Stricturing Behavior in Pediatric Crohn's Disease

scientific article published on 08 August 2020

Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature

scientific article

Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study

scientific article published on March 2017

Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets.

scientific article published on 29 January 2019

Quality indicators for inflammatory bowel disease: development of process and outcome measures

scientific article published on March 2013

Reduced expression of COVID-19 host receptor, ACE2 is associated with small bowel inflammation, more severe disease, and response to anti-TNF therapy in Crohn′s disease

scientific article published on 23 April 2020

Serologic Reactivity Reflects Clinical Expression of Ulcerative Colitis in Children

scientific article published on 01 May 2018

Serum Protein Biomarkers of Fibrosis Aid in Risk Stratification of Future Stricturing Complications in Pediatric Crohn's Disease

scientific article published on 01 May 2019

Single nucleotide polymorphisms that increase expression of the guanosine triphosphatase RAC1 are associated with ulcerative colitis

scientific article published on 4 May 2011

The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children

scientific article published on 28 September 2018

The treatment-naive microbiome in new-onset Crohn's disease

scientific article

Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease

scientific article published on 14 August 2017

Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response

scientific article published in Nature Communications

Utility of neutrophil Fcγ receptor I (CD64) index as a biomarker for mucosal inflammation in pediatric Crohn's disease

scientific article

Variation in Care in the Management of Children With Crohn's Disease: Data From a Multicenter Inception Cohort Study

scientific article published on 01 June 2019

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