List of works - Heather M Lamb

A deleted prion protein that is neurotoxic in vivo is localized normally in cultured cells

scientific article

A highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal death

scientific article

A prodrug approach for improving antituberculosis activity of potent Mycobacterium tuberculosis type II dehydroquinase inhibitors

scientific article

Competitive inhibitors of Helicobacter pylori type II dehydroquinase: synthesis, biological evaluation, and NMR studies.

scientific article

Connecting mitochondrial dynamics and life-or-death events via Bcl-2 family proteins

scientific article published on 28 April 2017

Determination of the bound conformation of a competitive nanomolar inhibitor of mycobacterium tuberculosis type II dehydroquinase by NMR spectroscopy

scientific article published on 01 September 2006

Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain

scientific article published in December 2000

Distinct mechanisms control RNA polymerase II recruitment to a tissue-specific locus control region and a downstream promoter

scientific article published on 01 August 2001

Double agents of cell death: novel emerging functions of apoptotic regulators

scientific article published on 01 April 2020

Histone deacetylase-dependent establishment and maintenance of broad low-level histone acetylation within a tissue-specific chromatin domain

scientific article

KCTD7 deficiency defines a distinct neurodegenerative disorder with a conserved autophagy-lysosome defect

Linking Notch signaling, chromatin remodeling, and T-cell leukemogenesis.

scientific article published in January 2000

Mechanistic basis of the inhibition of type II dehydroquinase by (2S)- and (2R)-2-benzyl-3-dehydroquinic acids

scientific article

Mycobacterium tuberculosis shikimate kinase inhibitors: design and simulation studies of the catalytic turnover

scientific article

Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125.

scientific article published on January 2007

Non-infectious aggregates of the prion protein react with several PrPSc-directed antibodies.

scientific article

Noncanonical functions of BCL-2 proteins in the nervous system

scientific article published on January 2010

Optimal promoter usage for lentiviral vector-mediated transduction of cultured central nervous system cells.

scientific article published on 27 March 2010

Overview of BCL-2 Family Proteins and Therapeutic Potentials

scientific article published on 01 January 2019

Prion protein lacks robust cytoprotective activity in cultured cells

scientific article published on 21 August 2008

Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues

scientific article

Tetrahydrobenzothiophene derivatives: conformationally restricted inhibitors of type II dehydroquinase

scientific article

The cellular prion protein (PrP(C)): its physiological function and role in disease

scientific article

Understanding the key factors that control the inhibition of type II dehydroquinase by (2R)-2-benzyl-3-dehydroquinic acids

scientific article

Unlatched BAX pairs for death

scientific article published on January 2013

List of works by Heather M Lamb

A deleted prion protein that is neurotoxic in vivo is localized normally in cultured cells

A highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal death

A prodrug approach for improving antituberculosis activity of potent Mycobacterium tuberculosis type II dehydroquinase inhibitors

Competitive inhibitors of Helicobacter pylori type II dehydroquinase: synthesis, biological evaluation, and NMR studies.

Connecting mitochondrial dynamics and life-or-death events via Bcl-2 family proteins

Determination of the bound conformation of a competitive nanomolar inhibitor of mycobacterium tuberculosis type II dehydroquinase by NMR spectroscopy

Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain

Distinct mechanisms control RNA polymerase II recruitment to a tissue-specific locus control region and a downstream promoter

Double agents of cell death: novel emerging functions of apoptotic regulators

Histone deacetylase-dependent establishment and maintenance of broad low-level histone acetylation within a tissue-specific chromatin domain

KCTD7 deficiency defines a distinct neurodegenerative disorder with a conserved autophagy-lysosome defect

Linking Notch signaling, chromatin remodeling, and T-cell leukemogenesis.

Mechanistic basis of the inhibition of type II dehydroquinase by (2S)- and (2R)-2-benzyl-3-dehydroquinic acids

Mycobacterium tuberculosis shikimate kinase inhibitors: design and simulation studies of the catalytic turnover

Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125.

Non-infectious aggregates of the prion protein react with several PrPSc-directed antibodies.

Noncanonical functions of BCL-2 proteins in the nervous system

Optimal promoter usage for lentiviral vector-mediated transduction of cultured central nervous system cells.

Overview of BCL-2 Family Proteins and Therapeutic Potentials

Prion protein lacks robust cytoprotective activity in cultured cells

Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues

Tetrahydrobenzothiophene derivatives: conformationally restricted inhibitors of type II dehydroquinase

The cellular prion protein (PrP(C)): its physiological function and role in disease

Understanding the key factors that control the inhibition of type II dehydroquinase by (2R)-2-benzyl-3-dehydroquinic acids

Unlatched BAX pairs for death