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List of works by Jacek Witkowski

Advanced application of CFSE for cellular tracking

scientific article

Alteration of high-density lipoprotein functionality in Alzheimer's disease patients

scientific article

Analysis of selected pro- and anti-inflammatory cytokines in patients with multiple injuries in the early period after trauma.

scientific article published on 30 March 2018

Are We Ill Because We Age?

scientific article published on 18 December 2019

Autoantibodies, C-reactive protein, erythrocyte sedimentation rate and serum cytokine profiling in monitoring of early treatment

scientific article published on 30 October 2017

Beta-amyloid peptides enhance the proliferative response of activated CD4CD28 lymphocytes from Alzheimer disease patients and from healthy elderly.

scientific article

CD3 receptor modulation in Jurkat leukemic cell line

scientific article published on January 2004

Can an Infection Hypothesis Explain the Beta Amyloid Hypothesis of Alzheimer's Disease?

Cellular Senescence, Immunosenescence and HIV.

scientific article published on 22 November 2016

Cellular signaling in the aging immune system

scientific article

Changes in proliferation kinetics of T cells: a new predictive cellular biomarkers for early rheumatoid arthritis?

scientific article

Changes in the Expression of Transcription Factors Involved in Modulating the Expression of EPO-R in Activated Human CD4-Positive Lymphocytes

scientific article

Characterization of glucose uptake by cultured rat podocytes.

scientific article published on 20 September 2004

Characterization of three-dimensional rat central nervous system culture maturation, with applications to monitor cholinergic integrity

scientific article published on 03 February 2020

Chemical variability of Rhododendron tomentosum (Ledum palustre) essential oils and their pro-apoptotic effect on lymphocytes and rheumatoid arthritis synoviocytes

scientific article published on 28 October 2019

Comment on "disease activity in patients with long‑lasting rheumatoid arthritis is associated with changes in peripheral blood lymphocyte subpopulations": authors' reply

scholarly article by Ewa Bryl et al published 1 January 2013 in Polish Archives of Internal Medicine

Comparison of the early chromatin reaction of the mouse thymocytes incubated with phytohemagglutinin and Concanavalin A ⬇️

scientific article published on February 27, 1976

Constipation and the Quality of Life in Conservatively Treated Chronic Kidney Disease Patients: A Cross-sectional Study

scientific article published on 18 October 2020

Conventional calpains and programmed cell death.

scientific article published on 29 August 2011

Cytokines of the Th1 and Th2 type in sera of rheumatoid arthritis patients; correlations with anti-Hsp40 immune response and diagnostic markers

article

Cytometric evaluation of transferrin receptor 1 (CD71) in childhood acute lymphoblastic leukemia.

scientific article published on 5 July 2012

Decreased proliferative capability of CD4(+) cells of elderly people is associated with faster loss of activation-related antigens and accumulation of regulatory T cells

scientific article published in April 2004

Dexamethasone-dependent modulation of cyclic GMP synthesis in podocytes.

scientific article

Different pattern of T-cell subpopulations in peripheral blood of patients with rheumatoid arthritis at various stages of disease development.

scientific article published on 15 November 2013

Differential Phenotypes of Myeloid-Derived Suppressor and T Regulatory Cells and Cytokine Levels in Amnestic Mild Cognitive Impairment Subjects Compared to Mild Alzheimer Diseased Patients

scientific article

Disease activity in patients with long-lasting rheumatoid arthritis is associated with changes in peripheral blood lymphocyte subpopulations

scientific article published on 20 November 2012

Do the oral Staphylococcus aureus strains from denture wearers have a greater pathogenicity potential?

scientific article published on 23 October 2018

Does CMV infection impact the virulence of Enterococcus faecalis?

scientific article published on October 2013

Does HIV infection contribute to increased beta-amyloid synthesis and plaque formation leading to neurodegeneration and Alzheimer's disease?

scientific article published on 13 March 2019

Dramatic shifts in circulating CD4 but not CD8 T cell subsets in mild Alzheimer's disease

scientific article

Early activation defects in T lymphocytes from aged mice ⬇️

scientific article published on December 1, 1997

Effect of angiotensin II on ANP-dependent guanylyl cyclase activity in cultured mouse and rat podocytes.

scientific article published on January 2002

Enhancement of Circulating and Intestinal T Regulatory Cells and Their Expression of Helios and Neuropilin-1 in Children with Inflammatory Bowel Disease

scientific article published on 26 November 2020

Erythropoietin Receptor Is Expressed on Human Peripheral Blood T and B Lymphocytes and Monocytes and Is Modulated by Recombinant Human Erythropoietin Treatment

scientific article published on 31 May 2010

Erythropoietin receptor is detectable on peripheral blood lymphocytes and its expression increases in activated T lymphocytes

scientific article published on March 2011

Ex vivo measurement of calpain activation in human peripheral blood lymphocytes by detection of immunoreactive products of calpastatin degradation

scientific article published on 01 January 2007

Excessive amount and activity of μ-calpain affects apoptotic machinery in chronic B-cell leukemia cells and influences the course of the disease

scientific article published on 16 June 2020

Expression of Hsp72 protein in chronic kidney disease patients.

scientific article published in January 2009

Expression of calpain-calpastatin system (CCS) member proteins in human lymphocytes of young and elderly individuals; pilot baseline data for the CALPACENT project

scientific article

Expression of heat shock protein 72 in peritoneal leukocytes is induced by peritoneal dialysis

scientific article published on 01 May 2007

Expression of scavenger receptor CD36 in chronic renal failure patients

scientific article published in August 2005

Flow cytometric analysis of STAT5 phosphorylation and CD95 expression in CD4+T lymphocytes treated with recombinant human erythropoietin

scientific article published on 01 June 2011

Flow cytometry approach study of Enterococcus faecalis vancomycin resistance by detection of Vancomycin@FL binding to the bacterial cells.

scientific article published on 2 April 2010

Frailty, Inflammation and Immunosenescence

scientific article published on 17 July 2015

Hemodialysis affects phenotype and proliferation of CD4-positive T lymphocytes.

scientific article published on 13 October 2011

Heterogeneity of methicillin-resistant Staphylococcus aureus strains (MRSA) characterized by flow cytometry

scientific article

Heterogeneity of the cytokinome in undifferentiated arthritis progressing to rheumatoid arthritis and its change in the course of therapy. Move toward personalized medicine

scientific article published on 25 May 2017

Heterogeneous susceptibility to spontaneous and induced apoptosis characterizes two related transplantable melanomas with different biological properties

scientific article published in June 2002

Homeostatic 'bystander' proliferation of human peripheral blood B cells in response to polyclonal T-cell stimulation in vitro.

scientific article published on 20 May 2015

Hsp40 proteins modulate humoral and cellular immune response in rheumatoid arthritis patients.

scientific article

Human CD4low CD25high regulatory T cells indiscriminately kill autologous activated T cells

scientific article published on 07 November 2008

Human Inflammaging

scientific article published on 03 May 2019

Immunological aspects of autoimmune thyroid disease - Complex interplay between cells and cytokines

scientific article published on 01 February 2019

Immunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes?

scientific article published in January 2017

Immunosenescence and cancer

scientific article published on January 2013

Impact of radiofrequency ablation on PBMC subpopulation in patients with renal cell carcinoma

scientific article published on 02 March 2010

Increased Pheromone cCF10 Expression in Enterococcus faecalis Biofilm Formed by Isolates from Renal Transplant Patients

scientific article published on 21 August 2012

Increased μ-Calpain Activity in Blasts of Common B-Precursor Childhood Acute Lymphoblastic Leukemia Correlates with Their Lower Susceptibility to Apoptosis.

scientific article published on 28 August 2015

Induction of G2/M phase arrest and apoptosis of human leukemia cells by potent antitumor triazoloacridinone C-1305.

scientific article published on 12 September 2006

Induction of binding of sheep red blood cells with the surface of mouse thymocytes by means of phytohaemagglutinin and concanavalin A ⬇️

scientific article published on January 15, 1977

Influence of hemodialysis on circulating CD4(low)CD25 (high) regulatory T cells in end-stage renal disease patients.

scientific article

Influence of oxygen concentration on T cell proliferation and susceptibility to apoptosis in healthy men and women.

scientific article published on January 2017

Isolation of xanthone and benzophenone derivatives from Cyclopia genistoides (L.) Vent. (honeybush) and their pro-apoptotic activity on synoviocytes from patients with rheumatoid arthritis.

scientific article

Klotho--a common link in physiological and rheumatoid arthritis-related aging of human CD4+ lymphocytes

scientific article published on 01 January 2007

Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework

scientific article published on 18 July 2020

Lactulose: Patient- and dose-dependent prebiotic properties in humans

scientific article published on 05 June 2019

Looking for the immunological “time window” for the surgical intervention in patients with polytrauma

scholarly article by Wojciech Marks et al published 2013 in Central-European Journal of Immunology

Mast cells in mastocytosis and allergy - Important player in metabolic and immunological homeostasis

scientific article published on 11 January 2019

Mechanical stress and glucose concentration modulate glucose transport in cultured rat podocytes.

scientific article

Microbiome impact on metabolism and function of sex, thyroid, growth and parathyroid hormones

scientific article published on 26 October 2015

Modulation of CD28 expression with anti-tumor necrosis factor α therapy in rheumatoid arthritis

scientific article published on 01 October 2005

Modulation of CD40L antigen expression in Jurkat cells: involvement of protein kinase C activity.

scientific article published in January 2003

Modulation of the activity of calcium-activated neutral proteases (calpains) in chronic lymphocytic leukemia (B-CLL) cells.

scientific article

NK Cells are Activated in Amnestic Mild Cognitive Impairment but not in Mild Alzheimer's Disease Patients

scientific article published on 26 February 2015

Natural Killer Cells, Aging, and Vaccination

scientific article published on 09 April 2020

Naturally occurring xanthone and benzophenone derivatives exert significant anti-proliferative and proapoptotic effects in vitro on synovial fibroblasts and macrophages from rheumatoid arthritis patients.

scientific article

On the immunological theory of aging

scientific article published on 13 May 2014

P-glycoprotein activity predicts outcome in childhood acute lymphoblastic leukemia.

scientific article published in July 2009

Paradoxical age-related cell cycle quickening of human CD4(+) lymphocytes: a role for cyclin D1 and calpain

scientific article published in April 2004

Pathophysiology of ageing, longevity and age related diseases

scientific article

Peripheral Immune Signatures in Alzheimer Disease

scientific article published on 21 February 2016

Peripheral blood lymphocyte subpopulations in patients with bipolar disorder type II

scientific article published on 10 April 2019

Phenotype, proliferation and apoptosis of B lymphocytes in hemodialysis patients treated with recombinant human erythropoietin

scientific article published on 8 July 2016

Polymorphonuclear Neutrophil Functions are Differentially Altered in Amnestic Mild Cognitive Impairment and Mild Alzheimer's Disease Patients

scientific article published on 29 July 2017

Proliferation and apoptosis of T lymphocytes in patients with bipolar disorder.

scientific article published on 20 February 2018

Prophages in enterococcal isolates from renal transplant recipients: renal failure etiologies promote selection of strains

scientific article

Protective Effect of Amyloid-β Peptides Against Herpes Simplex Virus-1 Infection in a Neuronal Cell Culture Model

scientific article published on 19 January 2016

Proteodynamics in aging human T cells - The need for its comprehensive study to understand the fine regulation of T lymphocyte functions

scientific article published on 13 October 2017

Recombinant Human Erythropoietin Treatment of Chronic Renal Failure Patients Normalizes Altered Phenotype and Proliferation of CD4-positive T Lymphocytes

scientific article published on 01 March 2010

Role of the peripheral innate immune system in the development of Alzheimer's disease

scientific article published on 21 December 2017

Roles of calpain-calpastatin system (CCS) in human T cell activation.

scientific article

Should we Try to Alleviate Immunosenescence and Inflammaging - Why, How and to What Extent?

scientific article published on 01 January 2019

Signal transduction changes in CD4+ and CD8+ T cell subpopulations with aging

scientific article published on 4 January 2018

T cells in IgA nephropathy: role in pathogenesis, clinical significance and potential therapeutic target

scientific article published on 07 November 2018

Targeting Infectious Agents as a Therapeutic Strategy in Alzheimer's Disease

scientific article published on 26 May 2020

The Level of Cytokines in the Vitreous Body of Severe Proliferative Diabetic Retinopathy Patients Undergoing Posterior Vitrectomy

scientific article published on 01 January 2018

The Role of Immunosenescence in the Development of Age-Related Diseases

scientific article published on March 2016

The conundrum of human immune system "senescence"

scientific article published on 16 September 2020

The high PMNs phagocytosis resistance of enterococcal isolates from RTx patients

scientific article published on 10 March 2015

The in vitro modulatory effect of TNFα on the mRNA expression and protein levels of zinc finger protein ZNF334 in CD4(+) lymphocytes of healthy people.

scientific article

The influence of a single hemodialysis procedure on human T lymphocytes

scientific article published on 25 March 2019

The influence of age on T cell generation and TCR diversity

scientific article

The influence of recombinant human erythropoietin on apoptosis and cytokine production of CD4+ lymphocytes from hemodialyzed patients.

scientific article published on 20 November 2012

The integration of inflammaging in age-related diseases

scientific article published on 02 October 2018

The role of elastin-derived peptides in human physiology and diseases

scientific article published on 08 July 2019

The significance of neonatal thymectomy for shaping the immune system in children with congenital heart defects

scientific article published on 20 December 2017

The tool better honed: Modern cytometric approach to protein phosphorylation

scientific article published on 4 April 2013

Two systemic lupus erythematosus (SLE) global disease activity indexes--the SLE Disease Activity Index and the Systemic Lupus Activity Measure--demonstrate different correlations with activation of peripheral blood CD4+ T cells.

scientific article published on 26 August 2011

Varying expression of four genes sharing a common regulatory sequence may differentiate rheumatoid arthritis from ageing effects on the CD4(+) lymphocytes

scientific article published on 25 August 2010

Viral strategies in modulation of NF-kappaB activity.

scientific article published on January 2003

Vitamin D status in patients with rheumatoid arthritis: a correlation analysis with disease activity and progression, as well as serum IL-6 levels

scientific article published on 5 December 2017

[Flow cytometric analysis of Enterococcus faecalis aph2"(+) response to aph2" (-) strains with high and low gene transfer rate]

scientific article published on 01 January 2005

[Flow cytometric analysys of Enterococcus faecalis pAD1(-) strains response to cAD1 pheromone]

scientific article published on 01 January 2005

[Mechanisms of the immune system ageing and some age-associated diseases].

scientific article

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