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List of works by Guy Boivin

1468. PCV13 Serotype Trends Over Time in Pneumococcal Community Acquired Pneumonia: Which Method(s) Work Best?

2714. Streptococcus pneumoniae Nasopharyngeal Carriage in Canadian Adults Hospitalized with Community-Acquired Pneumonia from 2010 to 2017

2715. Pneumococcal Community-Acquired Pneumonia Attributed to PCV13 Serotypes in Hospitalized Adults: Comparison of the 50–64 and 65+ Age Groups

97. Competition Experiments for the Baloxavir-Resistant I38T Influenza A Mutant

992. 2016–2017 Influenza Burden of Disease and End-of-Season Influenza Vaccine Effectiveness (VE) Estimates for Preventing Influenza-Related Hospitalization Among Canadian Adults: An Analysis From the Canadian Immunization Research Network (CIRN) S

article

A Cluster of Three Cases of Hantavirus Pulmonary Syndrome among Canadian Military Personnel

scientific article published on 10 April 2016

A Review of Clinical Influenza A and B Infections With Reduced Susceptibility to Both Oseltamivir and Zanamivir

scientific article

A novel neuraminidase deletion mutation conferring resistance to oseltamivir in clinical influenza A/H3N2 virus

scientific article published in January 2009

A reverse genetics study of resistance to neuraminidase inhibitors in an influenza A/H1N1 virus.

scientific article published in August 2004

A review of influenza vaccine immunogenicity and efficacy in HIV-infected adults

scientific article

A trial of valganciclovir prophylaxis for cytomegalovirus prevention in lung transplant recipients.

scientific article published in June 2005

Absence of cytomegalovirus-resistance mutations after valganciclovir prophylaxis, in a prospective multicenter study of solid-organ transplant recipients

scientific article published on 13 April 2004

Activity of the neuraminidase inhibitor A-315675 against oseltamivir-resistant influenza neuraminidases of N1 and N2 subtypes

scientific article published on 10 September 2007

Activity of the oral neuraminidase inhibitor A-322278 against the oseltamivir-resistant H274Y (A/H1N1) influenza virus mutant in mice

scientific article published on 17 November 2008

Adjuvant effect of the human metapneumovirus (HMPV) matrix protein in HMPV subunit vaccines

scientific article published on 17 December 2014

Adjuvanted inactivated influenza A(H3N2) vaccines induce stronger immunogenicity in mice and confer higher protection in ferrets than unadjuvanted inactivated vaccines

scientific article published on 27 August 2014

Age-stratified burden of pneumococcal community acquired pneumonia in hospitalised Canadian adults from 2010 to 2015

scientific article published on 01 March 2020

Amphipathic DNA polymers are candidate vaginal microbicides and block herpes simplex virus binding, entry and viral gene expression.

scientific article published on January 2007

Amphipathic DNA polymers exhibit antiherpetic activity in vitro and in vivo

scientific article published on 27 May 2008

An Early Microglial Response is Needed to Efficiently Control Herpes Simplex Virus Encephalitis

scientific article published on 16 September 2020

Analysis of HHV-6 mutations in solid organ transplant recipients at the onset of cytomegalovirus disease and following treatment with intravenous ganciclovir or oral valganciclovir

scientific article published on 16 July 2013

Analysis of cytomegalovirus DNA polymerase (UL54) mutations in solid organ transplant patients receiving valganciclovir or ganciclovir prophylaxis

scientific article published in November 2005

Analysis of replication kinetics of the human metapneumovirus in different cell lines by real-time PCR

scientific article

Antibiotic use in children is not influenced by the result of rapid antigen detection test for the respiratory syncytial virus

scientific article published on 25 May 2007

Antibody persistence and response to 2010-2011 trivalent influenza vaccine one year after a single dose of 2009 AS03-adjuvanted pandemic H1N1 vaccine in children

scientific article

Antiviral Agents in Development for Zika Virus Infections

scientific article published on 29 June 2019

Antiviral drug resistance in herpesviruses other than cytomegalovirus

scientific article published on 07 March 2014

Antiviral resistance in herpes simplex virus and varicella-zoster virus infections: diagnosis and management

scientific article published on 13 June 2016

Artesunate demonstrates in vitro synergism with several antiviral agents against human cytomegalovirus

scientific article published on 4 February 2016

Assessing the in vitro fitness of an oseltamivir-resistant seasonal A/H1N1 influenza strain using a mathematical model

scientific article

Association between the 2008-09 seasonal influenza vaccine and pandemic H1N1 illness during Spring-Summer 2009: four observational studies from Canada

scientific article

Both Cerebral and Hematopoietic Deficiencies in CCR2 Result in Uncontrolled Herpes Simplex Virus Infection of the Central Nervous System in Mice

scientific article

Both IRF3 and especially IRF7 play a key role to orchestrate an effective cerebral inflammatory response in a mouse model of herpes simplex virus encephalitis

scientific article published on 09 August 2018

Both TRIF and IPS-1 Adaptor Proteins Contribute to the Cerebral Innate Immune Response against Herpes Simplex Virus 1 Infection ⬇️

scientific article published on April 17, 2013

Burden of vaccine-preventable pneumococcal disease in hospitalized adults: A Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance (SOS) network study

scientific article published on 26 May 2017

CMV seropositivity is associated with increased microbial translocation in people living with HIV and uninfected controls

scientific article published on 14 October 2019

Canadian consensus guidelines for the management of cytomegalovirus disease in HIV/AIDS.

scientific article published on November 2004

Cell Culture Systems To Study Human Herpesvirus 6A/B Chromosomal Integration.

scientific article

Characterization of 2 influenza A(H3N2) clinical isolates with reduced susceptibility to neuraminidase inhibitors due to mutations in the hemagglutinin gene

scientific article published on 30 September 2002

Characterization of cellular transcriptomic signatures induced by different respiratory viruses in human reconstituted airway epithelia

scientific article published on 07 August 2019

Characterization of contemporary influenza B recombinant viruses harboring mutations of reduced susceptibility to baloxavir marboxil, in vitro and in mice

scientific article published on 25 April 2020

Characterization of drug-resistant influenza virus A(H1N1) and A(H3N2) variants selected in vitro with laninamivir

scientific article

Characterization of drug-resistant recombinant influenza A/H1N1 viruses selected in vitro with peramivir and zanamivir

scientific article published on 20 November 2006

Characterization of human cytomegalovirus (HCMV) UL97 mutations found in a valganciclovir/oral ganciclovir prophylactic trial by use of a bacterial artificial chromosome containing the HCMV genome

scientific article published on 24 July 2006

Characterization of human metapneumoviruses isolated from patients in North America

scientific article published on 3 May 2002

Characterization of multidrug-resistant influenza A/H3N2 viruses shed during 1 year by an immunocompromised child

scientific article published on 08 November 2006

Characterization of multiple cytomegalovirus drug resistance mutations detected in a hematopoietic stem cell transplant recipient by recombinant phenotyping

scientific article

Clinical development of letermovir and maribavir: Overview of human cytomegalovirus drug resistance

scientific article published on 25 January 2019

Combination Therapy with Oseltamivir and Favipiravir Delays Mortality but Does Not Prevent Oseltamivir Resistance in Immunodeficient Mice Infected with Pandemic A(H1N1) Influenza Virus

scientific article published in 2018

Comparative Evaluation of the Cytomegalovirus DNA Load in Polymorphonuclear Leukocytes and Plasma of Human Immunodeficiency Virus‐Infected Subjects ⬇️

scientific article published on February 1, 1998

Comparative evaluation of real-time PCR assays for detection of the human metapneumovirus

scientific article

Comparative evaluation of three serological methods for detection of human herpesvirus 8-specific antibodies in Canadian allogeneic stem cell transplant recipients

scientific article published on June 2004

Comparison of Automated Microarray Detection with Real-Time PCR Assays for Detection of Respiratory Viruses in Specimens Obtained from Children

scientific article published in April 2010

Comparison of automated microarray detection with real-time PCR assays for detection of respiratory viruses in specimens obtained from children

scientific article published on 21 January 2009

Comparison of early and recent influenza A(H1N1)pdm09 isolates harboring or not the H275Y neuraminidase mutation, in vitro and in animal models

scientific article published on 13 September 2018

Comparison of pandemic and seasonal influenza in the pediatric emergency department

scientific article

Comparison of risk factors for human metapneumovirus and respiratory syncytial virus disease severity in young children.

scientific article published on 2 May 2012

Comparison of the inhibition of human metapneumovirus and respiratory syncytial virus by ribavirin and immune serum globulin in vitro ⬇️

scientific article published on September 1, 2003

Compartmentalization of a Multidrug-Resistant Cytomegalovirus UL54 Mutant in a Stem Cell Transplant Recipient with Encephalitis

scientific article published on 01 September 2019

Contagious period for pandemic (H1N1) 2009.

scientific article

Contrasting effects of W781V and W780V mutations in helix N of herpes simplex virus 1 and human cytomegalovirus DNA polymerases on antiviral drug susceptibility

scientific article published on 11 February 2015

Contrasting effects on ganciclovir susceptibility and replicative capacity of two mutations at codon 466 of the human cytomegalovirus UL97 gene ⬇️

scientific article published on September 16, 2010

Cross-lineage influenza B and heterologous influenza A antibody responses in vaccinated mice: immunologic interactions and B/Yamagata dominance

scientific article (publication date: 2012)

Cross-reactive and vaccine-induced antibody to an emerging swine-origin variant of influenza A virus subtype H3N2 (H3N2v).

scientific article published on 7 August 2012

Cross-reactive antibody to swine influenza A(H3N2) subtype virus in children and adults before and after immunisation with 2010/11 trivalent inactivated influenza vaccine in Canada, August to November 2010 ⬇️

scientific article published on January 26, 2012

Cytomegalovirus (CMV) glycoprotein B genotypes and response to antiviral therapy, in solid-organ-transplant recipients with CMV disease

scientific article published on 29 July 2003

Cytomegalovirus (CMV) virus load kinetics to predict recurrent disease in solid-organ transplant patients with CMV disease

scientific article published on 28 August 2002

Cytomegalovirus quantification in plasma with Abbott RealTime CMV and Roche Cobas Amplicor CMV assays

scientific article published on September 2015

Cytomegalovirus resistance in solid organ transplant recipients treated with intravenous ganciclovir or oral valganciclovir

scientific article published in January 2009

Cytomegalovirus ventriculoencephalitis in a peripheral blood stem cell transplant recipient

scientific article published on 6 January 2006

DNA vaccination protects mice against Zika virus-induced damage to the testes

scientific article

Delayed but not early glucocorticoid treatment protects the host during experimental herpes simplex virus encephalitis in mice

scientific article published on 7 February 2007

Design and Validation with Influenza A Virus of an Aerosol Transmission Chamber for Ferrets

article

Design considerations in building in silico equivalents of common experimental influenza virus assays.

scientific article published on 19 January 2011

Detection and management of antiviral resistance for influenza viruses

scientific article

Detection of human metapneumovirus antigens in nasopharyngeal aspirates using an enzyme immunoassay

scientific article published on 17 November 2008

Development and validation of an enzyme-linked immunosorbent assay for human metapneumovirus serology based on a recombinant viral protein

scientific article published on February 2005

Development of a serological assay based on a synthetic peptide selected from the VP0 capsid protein for detection of human parechoviruses

scientific article published on 18 April 2007

Development of a universal influenza A vaccine based on the M2e peptide fused to the papaya mosaic virus (PapMV) vaccine platform.

scientific article published on 12 May 2008

Diagnosis of herpesvirus infections of the central nervous system.

scientific article published in June 2004

Discordant phenotypes and genotypes of cytomegalovirus (CMV) in patients with AIDS and relapsing CMV retinitis

scientific article

Disseminated herpes simplex virus type 1 primary infection in a healthy individual

scientific article

Distribution and clinical impact of human respiratory syncytial virus genotypes in hospitalized children over 2 winter seasons

scientific article

Divergent evolution of hemagglutinin and neuraminidase genes in recent influenza A:H3N2 viruses isolated in Canada

scientific article published on 01 August 2002

Droplet Digital PCR and Immunohistochemistry Techniques to Detect Zika Virus in the Central Nervous System of Mice

scientific article published on 01 January 2020

Droplet digital PCR to investigate quasi-species at codons 119 and 275 of the A(H1N1)pdm09 neuraminidase during zanamivir and oseltamivir therapies

scientific article published on 7 September 2016

Drug Susceptibility and Replicative Capacity of Multi-Drug Resistant Recombinant Human Cytomegalovirus Harboring Mutations in UL56 and UL54 Genes

scientific article published on 14 August 2017

Drug resistance patterns of recombinant herpes simplex virus DNA polymerase mutants generated with a set of overlapping cosmids and plasmids

scientific article

Drug-resistant herpesviruses: Should we look for them? ⬇️

scientific article published on August 1, 1998

E119D Neuraminidase Mutation Conferring Pan-Resistance to Neuraminidase Inhibitors in an A(H1N1)pdm09 Isolate From a Stem-Cell Transplant Recipient

scientific article

Effect of in vitro syncytium formation on the severity of human metapneumovirus disease in a murine model

scientific article published on 24 March 2015

Effect of pretreatment with toll-like receptor agonists in a mouse model of herpes simplex virus type 1 encephalitis

scientific article published in September 2008

Effect of ribavirin and glucocorticoid treatment in a mouse model of human metapneumovirus infection

scientific article

Effect of the neuraminidase mutation H274Y conferring resistance to oseltamivir on the replicative capacity and virulence of old and recent human influenza A(H1N1) viruses

scientific article published in March 2010

Effectiveness of Influenza Vaccination on Hospitalizations and Risk Factors for Severe Outcomes in Hospitalized Patients With COPD

scientific article published on 01 January 2019

Effects of Different Drug Combinations in Immunodeficient Mice Infected with an Influenza A/H3N2 Virus

scientific article published on 11 December 2020

Effects of different adjuvants in the context of intramuscular and intranasal routes on humoral and cellular immune responses induced by detergent-split A/H3N2 influenza vaccines in mice

scientific article published on 21 December 2011

Emergence and prevalence of cytomegalovirus UL97 mutations associated with ganciclovir resistance in AIDS patients ⬇️

scientific article published on January 22, 1998

Emergence of an oseltamivir-resistant influenza A/H3N2 virus in an elderly patient receiving a suboptimal dose of antiviral prophylaxis

scientific article published on 02 October 2013

Emergence of oseltamivir-resistant pandemic H1N1 virus during prophylaxis

scientific article published on 11 November 2009

Engineering of Live Chimeric Vaccines against Human Metapneumovirus

scientific article published on 19 February 2020

Enhanced lung disease and Th2 response following human metapneumovirus infection in mice immunized with the inactivated virus

scientific article published on December 2007

Epidemiology of Influenza Viruses in Canada over the 2011–2012 to 2013–2014 Seasons: A Study from the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN).

scientific article published on 4 October 2017

Epitope mapping of the 2009 pandemic and the A/Brisbane/59/2007 seasonal (H1N1) influenza virus haemagglutinins using mAbs and escape mutants.

scientific article

Estradiol is required for a proper immune response to bacterial and viral pathogens in the female brain

scientific article published in May 2005

Evaluation of Epstein-Barr virus, human herpesvirus 6 (HHV-6), and HHV-8 antiviral drug susceptibilities by use of real-time-PCR-based assays

scientific article published on 16 January 2013

Evaluation of anticoagulant agents for the treatment of human metapneumovirus infection in mice

scientific article published on 10 August 2018

Evaluation of pre- and post-fusion Human metapneumovirus F proteins as subunit vaccine candidates in mice

scientific article published on 29 January 2020

Evaluation of recombinant 2009 pandemic influenza A (H1N1) viruses harboring zanamivir resistance mutations in mice and ferrets.

scientific article

Evaluation of serological diagnostic methods for the 2009 pandemic influenza A (H1N1) virus

scientific article

Evaluation of susceptibility of human herpesvirus 8 to antiviral drugs by quantitative real-time PCR.

scientific article

Evaluation of the AMPLICOR Cytomegalovirus Test with Specimens from Human Immunodeficiency Virus-Infected Subjects ⬇️

scientific article published on September 1, 1998

Evolution of oseltamivir resistance mutations in Influenza A(H1N1) and A(H3N2) viruses during selection in experimentally infected mice.

scientific article

Evolution of surface and nonstructural-1 genes of influenza B viruses isolated in the Province of Québec, Canada, during the 1998-2001 period

scientific article published on October 1, 2003

Fitness of influenza A and B viruses with reduced susceptibility to baloxavir: A mini-review

scientific article published on 25 September 2020

Frailty Hinders Recovery From Acute Respiratory Illness in Older Adults

Frailty Hinders Recovery From Influenza and Acute Respiratory Illness in Older Adults

scientific article published on 09 March 2020

Generation and characterization of recombinant influenza A (H1N1) viruses harboring amantadine resistance mutations

scientific article

Generation and characterization of recombinant pandemic influenza A(H1N1) viruses resistant to neuraminidase inhibitors

scientific article

Genetic diversity and molecular evolution of the major human metapneumovirus surface glycoproteins over a decade.

scientific article published on 4 September 2013

Genetic diversity between human metapneumovirus subgroups ⬇️

scientific article published on October 10, 2003

Global genetic diversity of human metapneumovirus fusion gene

scientific article published in June 2004

Herpes simplex encephalitis in adult patients with MASP-2 deficiency

scientific article published on 23 December 2019

Herpes simplex virus isolates with reduced adefovir susceptibility selected in vivo by foscarnet therapy

scientific article published in May 2002

Herpesvirus DNA polymerases: Structures, functions and inhibitors

scientific article published on 30 January 2017

Heterosubtypic protection conferred by the human monoclonal antibody PN-SIA28 against influenza A virus lethal infections in mice

scientific article

Host and viral factors affecting clinical performance of a rapid diagnostic test for respiratory syncytial virus in hospitalized children

scientific article published on 30 April 2013

Household transmission of the 2009 pandemic A/H1N1 influenza virus: elevated laboratory‐confirmed secondary attack rates and evidence of asymptomatic infections.

scientific article

Human Respiratory Syncytial Virus-induced immune signature of infection revealed by transcriptome analysis of clinical pediatric nasopharyngeal swab samples

scientific article published on 29 July 2020

Human bocavirus infections in hospitalized children and adults

scientific article published on February 2008

Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice

scientific article published on 09 April 2019

Human metapneumovirus genetic variability, South Africa

scientific article

Human metapneumovirus infection in immunocompromised child

scientific article published in May 2008

Human metapneumovirus infection induces long-term pulmonary inflammation associated with airway obstruction and hyperresponsiveness in mice.

scientific article published on 11 May 2006

Human metapneumovirus infections in hospitalized children

scientific article

Human metapneumovirus viral load is an important risk factor for disease severity in young children

scientific article published on 12 March 2014

Human metapneumovirus, Peru

scientific article

Human metapneumovirus-associated lower respiratory tract infections among hospitalized human immunodeficiency virus type 1 (HIV-1)-infected and HIV-1-uninfected African infants

scientific article published on 19 November 2003

Human metapneumovirus.

scientific article

Human metapneumovirus: a new player among respiratory viruses

scientific article published on 15 March 2004

Human metapneumovirus: a ubiquitous and long-standing respiratory pathogen

scientific article

Human metapneumovirus: enhanced pulmonary disease in cotton rats immunized with formalin-inactivated virus vaccine and challenged.

scientific article published on 15 May 2007

Human parainfluenza type 4 infections, Canada

scientific article

Human parechovirus 3 and neonatal infections

scientific article published on January 2005

Human parechovirus causes encephalitis with white matter injury in neonates

scientific article published on September 2008

Human parechovirus types 1, 2 and 3 infections in Canada

scientific article

Human respiratory syncytial virus and other viral infections in infants receiving palivizumab

scientific article

Hydroxyurea enhances the activity of acyclovir and cidofovir against herpes simplex virus type 1 resistant strains harboring mutations in the thymidine kinase and/or the DNA polymerase genes

scientific article published on 17 September 2007

Hypersusceptibility of Human Cytomegalovirus to Foscarnet Induced by Mutations in Helices K and P of the Viral DNA Polymerase

scientific article published on 24 March 2020

Identification and evaluation of a highly effective fusion inhibitor for human metapneumovirus

scientific article

Immunogenicity Is Not Improved by Increased Antigen Dose or Booster Dosing of Seasonal Influenza Vaccine in a Randomized Trial of HIV Infected Adults ⬇️

scientific article published on March 25, 2011

Immunogenicity and tolerability of an inactivated and adjuvanted pandemic H1N1 influenza vaccine, in HIV-1-infected patients

scientific article

Immunomodulatory Strategies in Herpes Simplex Virus Encephalitis

scientific article published on 12 February 2020

Impact of Antivirals in the Prevention of Serious Outcomes Associated with Influenza in Hospitalized Canadian Adults: A Pooled Analysis from the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN).

scientific article published on 4 October 2017

Impact of Prior Season Influenza Vaccination on Seasonal Influenza Vaccine Effectiveness: An Analysis over Four Consecutive Seasons from the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN).

scientific article

Impact of R152K and R368K neuraminidase catalytic substitutions on in vitro properties and virulence of recombinant A(H1N1)pdm09 viruses.

scientific article published on 16 April 2018

Impact of a large deletion in the neuraminidase protein identified in a laninamivir-selected influenza A/Brisbane/10/2007 (H3N2) variant on viral fitness in vitro and in ferrets

scientific article

Impact of deficiency in CCR2 and CX3CR1 receptors on monocytes trafficking in herpes simplex virus encephalitis

scientific article published on 29 February 2012

Impact of mutations at residue I223 of the neuraminidase protein on the resistance profile, replication level, and virulence of the 2009 pandemic influenza virus

scientific article

Impact of neuraminidase mutations conferring influenza resistance to neuraminidase inhibitors in the N1 and N2 genetic backgrounds.

scientific article published on January 2006

Impact of potential permissive neuraminidase mutations on viral fitness of the H275Y oseltamivir-resistant influenza A(H1N1)pdm09 virus in vitro, in mice and in ferrets.

scientific article

Impact of the Baloxavir-Resistant Polymerase Acid I38T Substitution on the Fitness of Contemporary Influenza A(H1N1)pdm09 and A(H3N2) Strains

scientific article published on 01 January 2020

Impact of the H275Y and I223V Mutations in the Neuraminidase of the 2009 Pandemic Influenza Virus In Vitro and Evaluating Experimental Reproducibility

scientific article

Importance of viral and bacterial infections in chronic obstructive pulmonary disease exacerbations

scientific article published on 7 August 2009

In Vitro Combinations of Baloxavir Acid and Other Inhibitors against Seasonal Influenza A Viruses

scientific article published on 08 October 2020

In Vitro Properties and Virulence of Contemporary Recombinant Influenza B Viruses Harboring Mutations of Cross-Resistance to Neuraminidase Inhibitors

scientific article published in 2018

In vitro activity of letermovir against human cytomegalovirus isolates with different drug susceptibility phenotypes

scientific article published in 2022

In vitro and in vivo evidence of a potential A(H1N1)pdm09 antigenic drift mediated by escape mutations in the haemagglutinin Sa antigenic site

scientific article published on 20 June 2017

In vitro susceptibility of geographically and temporally distinct zika viruses to favipiravir and ribavirin

scientific article published on 11 July 2017

Incidence and characterization of cytomegalovirus resistance mutations among pediatric solid organ transplant patients who received valganciclovir prophylaxis

scientific article published on 6 February 2010

Incidence of cytomegalovirus UL97 and UL54 amino acid substitutions detected after 100 or 200 days of valganciclovir prophylaxis

scientific article

Infection with human metapneumovirus predisposes mice to severe pneumococcal pneumonia

scientific article

Infections by human coronavirus-NL in hospitalized children

scientific article

Infiltration Pattern of Blood Monocytes into the Central Nervous System during Experimental Herpes Simplex Virus Encephalitis

scientific article published on 23 December 2015

Influenza drug resistance

scientific article published on 19 August 2011

Influenza vaccine effectiveness against influenza-related hospitalization during a season with mixed outbreaks of four influenza viruses: a test-negative case-control study in adults in Canada

scientific article published on 29 December 2017

Influenza vaccine effectiveness to prevent influenza-related hospitalizations and serious outcomes in Canadian adults over the 2011/12 through 2013/14 influenza seasons: A pooled analysis from the Canadian Immunization Research Network (CIRN) Seriou

scientific article published on 13 March 2018

Influenza virus activates human immunodeficiency virus type-1 gene expression in human CD4-expressing T cells through an NF-kappaB-dependent pathway

scientific article published in February 2005

Influenza virus epidemiology: a permanent vaccine challenge

scientific article published on 01 October 2019

Influenza virus resistance to neuraminidase inhibitors.

scientific article

Influenza virus shedding: excretion patterns and effects of antiviral treatment

scientific article published on 09 March 2009

Influenza virus susceptibility and resistance to oseltamivir.

scientific article published on January 2007

Influenzavirus infection is a primary cause of febrile respiratory illness in HIV-infected adults, despite vaccination

scientific article

Inhibition of human metapneumovirus replication by small interfering RNA.

scientific article published on January 2008

Innate immune response during herpes simplex virus encephalitis and development of immunomodulatory strategies

scientific article published on 23 July 2015

Intrahost dynamics of antiviral resistance in influenza A virus reflect complex patterns of segment linkage, reassortment, and natural selection

scientific article published on 7 April 2015

Intranasal herpes simplex virus type 2 inoculation causes a profound thymidine kinase dependent cerebral inflammatory response in the mouse hindbrain

scientific article published in July 2002

Lack of Emergence of Cytomegalovirus UL97 Mutations Conferring Ganciclovir (GCV) Resistance following Preemptive GCV Therapy in Allogeneic Stem Cell Transplant Recipients ⬇️

scientific article published on December 1, 2001

Long-term impairment of Streptococcus pneumoniae lung clearance is observed after initial infection with influenza A virus but not human metapneumovirus in mice

scientific article published on 16 March 2011

Longitudinal evaluation of herpes simplex virus DNA load during episodes of herpes labialis

scientific article published on December 2006

Low systemic ganciclovir exposure and preemptive treatment failure of cytomegalovirus reactivation in a transplanted child

scientific article published on 10 May 2011

Management and prevention of herpes zoster: A Canadian perspective

scientific article

Mapping and characterization of the primary and anamnestic H-2(d)-restricted cytotoxic T-lymphocyte response in mice against human metapneumovirus

scientific article

Microglia are involved in phagocytosis and extracellular digestion during Zika virus encephalitis in young adult immunodeficient mice

scientific article

Modified cyclodextrins as broad-spectrum antivirals

scientific article published on 29 January 2020

Modulation of TLR9 response in a mouse model of herpes simplex virus encephalitis ⬇️

scientific article published on October 6, 2012

Modulation of protease activated receptor 1 influences human metapneumovirus disease severity in a mouse model

scientific article

Molecular and antigenic evolution of human influenza A/H3N2 viruses in Quebec, Canada, 2009-2011.

scientific article published on 28 October 2011

Molecular and epidemiologic investigation of a rhinovirus outbreak in a neonatal intensive care unit

scientific article published on 05 December 2018

Molecular characterization of a Canadian human parechovirus (HPeV)-3 isolate and its relationship to other HPeVs

scientific article published in December 2005

Molecular characterization of viruses from clinical respiratory samples producing unidentified cytopathic effects in cell culture

scientific article

Molecular evolution of respiratory syncytial virus fusion gene, Canada, 2006-2010.

scientific article published in January 2012

Molecular pathway of influenza pan-neuraminidase inhibitor resistance in an immunocompromised patient

scientific article published on 07 February 2020

Multi-year study of human metapneumovirus infection at a large US Midwestern Medical Referral Center

scientific article published on 27 September 2006

Multiplex real-time PCR assay for detection of influenza and human respiratory syncytial viruses.

scientific article

Mutations in the fusion protein heptad repeat domains of human metapneumovirus impact on the formation of syncytia

scientific article

Neuraminidase-inhibitor resistance testing for pandemic influenza A (H1N1) 2009 in Ontario, Canada

scientific article

Neurovirulence and latency of drug-resistant clinical herpes simplex viruses in animal models

scientific article published in May 2010

New Saffold cardioviruses in 3 children, Canada

scientific article (publication date: May 2008)

Novel Method Based on Real-Time Cell Analysis for Drug Susceptibility Testing of Herpes Simplex Virus and Human Cytomegalovirus

scientific article published on June 2016

Novel antiviral compounds and combination therapy for influenza viruses

scientific article published on 01 December 2019

Novel antiviral compounds and combination therapy for influenza viruses

scientific article published in December 2019

Novel calixarene-based surfactant enables low dose split inactivated vaccine protection against influenza infection

scientific article published on 18 October 2019

Novel method based on "en passant" mutagenesis coupled with a gaussia luciferase reporter assay for studying the combined effects of human cytomegalovirus mutations

scientific article published on 17 July 2013

OVX836 a recombinant nucleoprotein vaccine inducing cellular responses and protective efficacy against multiple influenza A subtypes

article

Opposite effect of two cytomegalovirus DNA polymerase mutations on replicative capacity and polymerase activity

scientific article published in January 2010

Optimization of Droplet Digital PCR from RNA and DNA extracts with direct comparison to RT-qPCR: Clinical implications for quantification of Oseltamivir-resistant subpopulations.

scientific article

Oseltamivir-resistant pandemic A/H1N1 virus is as virulent as its wild-type counterpart in mice and ferrets

scientific article

Oseltamivir-zanamivir combination therapy is not superior to zanamivir monotherapy in mice infected with influenza A(H3N2) and A(H1N1)pdm09 viruses.

scientific article published on 28 February 2014

Parenteral peramivir treatment for Oseltamivir-resistant 2009 pandemic influenza A H1N1 viruses

scientific article published on 23 September 2011

Pathogenesis of human metapneumovirus lung infection in BALB/c mice and cotton rats

scientific article published on July 2005

Pathogenicity and response to topical antiviral therapy in a murine model of acyclovir-sensitive and acyclovir-resistant herpes simplex viruses isolated from the same patient

scientific article published on 16 June 2006

Peramivir susceptibilities of recombinant influenza A and B variants selected with various neuraminidase inhibitors

scientific article published on 22 March 2017

Permissive changes in the neuraminidase play a dominant role in improving the viral fitness of oseltamivir-resistant seasonal influenza A(H1N1) strains.

scientific article published on 12 December 2014

Phenotypic and Genotypic Characterization of Acyclovir-Resistant Herpes Simplex Viruses from Immunocompromised Patients ⬇️

scientific article published on August 1, 1998

Phenotypic evaluation of previously uncharacterized cytomegalovirus DNA polymerase sequence variants detected in a valganciclovir treatment trial

scientific article

Plastic polymers for efficient DNA microarray hybridization: application to microbiological diagnostics

scientific article published on 10 September 2008

Predominant role of IPS-1 over TRIF adaptor proteins in early innate immune response against Zika virus in mice

scientific article published on 3 January 2018

Presence of oseltamivir-resistant pandemic A/H1N1 minor variants before drug therapy with subsequent selection and transmission.

scientific article

Prolonged excretion of amantadine-resistant influenza a virus quasi species after cessation of antiviral therapy in an immunocompromised patient

scientific article published on 23 January 2002

Prophylactic activity of intramuscular peramivir in mice infected with a recombinant influenza A/WSN/33 (H1N1) virus containing the H274Y neuraminidase mutation

scientific article published on 19 April 2010

Prophylactic and therapeutic benefits of a monoclonal antibody against the fusion protein of human metapneumovirus in a mouse model.

scientific article

Protease-activated receptor 1 inhibition protects mice against thrombin-dependent respiratory syncytial virus and human metapneumovirus infections

scientific article published on 4 November 2017

Protective role of CX3CR1 signalling in resident cells of the central nervous system during experimental herpes simplex virus encephalitis

scientific article published on 30 November 2016

Quantification of human herpesvirus 8 by real-time PCR in blood fractions of AIDS patients with Kaposi's sarcoma and multicentric Castleman's disease

scientific article published in November 2002

Quantification of the influenza virus load by real-time polymerase chain reaction in nasopharyngeal swabs of patients treated with oseltamivir

scientific article published on 5 August 2003

Quantitation of Cytomegalovirus: Methodologic Aspects and Clinical Applications ⬇️

scientific article published on July 1, 1998

Randomized controlled ferret study to assess the direct impact of 2008-09 trivalent inactivated influenza vaccine on A(H1N1)pdm09 disease risk

scientific article

Recent developments with live-attenuated recombinant paramyxovirus vaccines

scientific article published on 08 May 2012

Recombinant Phenotyping of Cytomegalovirus Sequence Variants Detected After 200 or 100 Days of Valganciclovir Prophylaxis ⬇️

scientific article published on December 27, 2010

Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet

scientific article

Reduced Susceptibility to Neuraminidase Inhibitors in Influenza B Isolate, Canada

article

Reduced airborne transmission of oseltamivir-resistant pandemic A/H1N1 virus in ferrets

scientific article

Reply to "Calibration technologies for correct determination of Epstein-Barr Virus, human herpesvirus 6 (HHV-6), and HHV-8 antiviral drug susceptibilities by use of real-time-PCR-based assays".

scientific article published in June 2013

Repurposing of Drugs as Novel Influenza Inhibitors From Clinical Gene Expression Infection Signatures

article

Resistance of herpes simplex viruses to nucleoside analogues: mechanisms, prevalence, and management

scientific article

Resistance of herpesviruses to antiviral drugs: clinical impacts and molecular mechanisms

scientific article

Resource utilization and cost of influenza requiring hospitalization in Canadian adults: A study from the serious outcomes surveillance network of the Canadian Immunization Research Network

scientific article published on 10 November 2017

Respiratory tract reinfections by the new human Metapneumovirus in an immunocompromised child

scientific article published on September 2002

Risk factors for hospitalization and severe outcomes of 2009 pandemic H1N1 influenza in Quebec, Canada.

scientific article

Role of helix P of the human cytomegalovirus DNA polymerase in resistance and hypersusceptibility to the antiviral drug foscarnet

scientific article

Role of permissive neuraminidase mutations in influenza A/Brisbane/59/2007-like (H1N1) viruses

scientific article

Role of picornaviruses in flu-like illnesses of adults enrolled in an oseltamivir treatment study who had no evidence of influenza virus infection

scientific article

Sequence analysis of the N, P, M and F genes of Canadian human metapneumovirus strains.

scientific article published in May 2003

Sequence polymorphism of the predicted human metapneumovirus G glycoprotein

scientific article published on March 2004

Seroconversion to seasonal influenza viruses after A(H1N1)pdm09 virus infection, Quebec, Canada

scientific article

Single-cell transcriptomics of the ventral posterolateral nucleus-enriched thalamic regions from HSV-1-infected mice reveal a novel microglia/microglia-like transcriptional response

scientific article published on 06 April 2022

Standardization of Hemagglutination Inhibition Assay for Influenza Serology Allows for High Reproducibility between Laboratories

scientific article published on 27 January 2016

Strain-Dependent Impact of G and SH Deletions Provide New Insights for Live-Attenuated HMPV Vaccine Development

scientific article published on 30 October 2019

Streptococcus pneumoniae serotype 3 is masking PCV13-mediated herd immunity in Canadian adults hospitalized with community acquired pneumonia: A study from the Serious Outcomes Surveillance (SOS) Network of the Canadian immunization research Network

scientific article published on 23 July 2019

Structural Insight into NS5 of Zika Virus Leading to the Discovery of MTase Inhibitors

scientific article (publication date: 21 December 2016)

Susceptibility of recent Canadian influenza A and B virus isolates to different neuraminidase inhibitors

scientific article published in June 2002

Syncytium formation and HIV-1 replication are both accentuated by purified influenza and virus-associated neuraminidase

scientific article published on 7 January 2002

Synergistic PA and HA mutations confer mouse adaptation of a contemporary A/H3N2 influenza virus

scientific article published on 12 November 2019

Systematic review of influenza resistance to the neuraminidase inhibitors

scientific article

Targeted Proteomics of Human Metapneumovirus in Clinical Samples and Viral Cultures.

scientific article published on 16 September 2015

The 2009 pandemic H1N1 D222G hemagglutinin mutation alters receptor specificity and increases virulence in mice but not in ferrets

scientific article

The E119D neuraminidase mutation identified in a multidrug-resistant influenza A(H1N1)pdm09 isolate severely alters viral fitness in vitro and in animal models

scientific article published on 13 May 2016

The H275Y neuraminidase mutation of the pandemic A/H1N1 influenza virus lengthens the eclipse phase and reduces viral output of infected cells, potentially compromising fitness in ferrets.

scientific article

The I222V neuraminidase mutation has a compensatory role in replication of an oseltamivir-resistant influenza virus A/H3N2 E119V mutant

scientific article published on 24 November 2010

The I427T neuraminidase (NA) substitution, located outside the NA active site of an influenza A(H1N1)pdm09 variant with reduced susceptibility to NA inhibitors, alters NA properties and impairs viral fitness.

scientific article published on 9 November 2016

The Importance of Frailty in the Assessment of Influenza Vaccine Effectiveness Against Influenza-Related Hospitalization in Elderly People

article

The Nonstructural NS1 Protein of Influenza Viruses Modulates TP53 Splicing through Host Factor CPSF4

scientific article published on 21 March 2019

The Val430Ile neuraminidase (NA) substitution, identified in influenza B virus isolates, impacts the catalytic 116Arg residue causing reduced susceptibility to NA inhibitors

scientific article published on 16 July 2019

The combination of oseltamivir with azithromycin does not show additional benefits over oseltamivir monotherapy in mice infected with influenza A(H1N1)pdm2009 virus.

scientific article published on 9 August 2017

The combination of valacyclovir with an anti-TNF alpha antibody increases survival rate compared to antiviral therapy alone in a murine model of herpes simplex virus encephalitis

scientific article published on December 2013

The distinguishing features of human metapneumovirus and respiratory syncytial virus

scientific article published on July 2010

The need for validation of statistical methods for estimating respiratory virus-attributable hospitalization

scientific article published on 13 August 2009

The prophylactic administration of a monoclonal antibody against human metapneumovirus attenuates viral disease and airways hyperresponsiveness in mice

scientific article published on 01 January 2008

The quest for a nanoparticle-based vaccine inducing broad protection to influenza viruses

scientific article published on 05 September 2018

The recruitment of peripheral blood leukocytes to the brain is delayed in susceptible BALB/c compared to resistant C57BL/6 mice during herpes simplex virus encephalitis

scientific article published on 13 February 2019

Therapeutic activity of intramuscular peramivir in mice infected with a recombinant influenza A/WSN/33 (H1N1) virus containing the H275Y neuraminidase mutation

scientific article

Three-dimensional modeling of cytomegalovirus DNA polymerase and preliminary analysis of drug resistance

scientific article published on 01 August 2006

Thymidine kinase mutations conferring acyclovir resistance in herpes simplex type 1 recombinant viruses

scientific article published on 18 September 2006

Treatment of respiratory virus infections

scientific article

Treatment with a novel topical nanoemulsion (NB-001) speeds time to healing of recurrent cold sores

scientific article published on August 1, 2012

Tumor necrosis factor-alpha and interleukin-1 beta play a critical role in the resistance against lethal herpes simplex virus encephalitis

scientific article

Valacyclovir combined with artesunate or rapamycin improves the outcome of herpes simplex virus encephalitis in mice compared to antiviral therapy alone

scientific article published on 13 September 2015

Viral pathogens including human metapneumovirus are the primary cause of febrile respiratory illness in HIV-infected adults receiving antiretroviral therapy

scientific article published on January 2010

Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groups

scientific article published on 8 October 2002

Virus-like particle vaccine induces cross-protection against human metapneumovirus infections in mice

scientific article published on 11 April 2013

WU polyomavirus in children, Canada

scientific article

Whole-genome characterization and genotyping of global WU polyomavirus strains

scientific article published on 31 March 2010

Zika-Induced Male Infertility in Mice Is Potentially Reversible and Preventable by Deoxyribonucleic Acid Immunization

article

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