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List of works by Rüdiger Hardeland

A Comparison of B16 Melanoma Cells and 3T3 Fibroblasts Concerning Cell Viability and ROS Production in the Presence of Melatonin, Tested Over a Wide Range of Concentrations

scientific article published on 14 February 2013

Activity of cathepsins during beef aging related to mutations in the myostatin gene

article

Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks ⬇️

scientific article published on 11 March 2019

Amphiphilic amide nitrones: a new class of protective agents acting as modifiers of mitochondrial metabolism

scientific article published in July 2010

Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages

scientific article published on August 2005

Antioxidant activity in Spalax ehrenbergi: a possible adaptation to underground stress.

scientific article published on 15 February 2006

Antioxidant properties of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK): scavenging of free radicals and prevention of protein destruction

scientific article published in January 2003

Antioxidative Protection by Melatonin: Multiplicity of Mechanisms from Radical Detoxification to Radical Avoidance

scientific article

C5a anaphylatoxin as a product of complement activation up-regulates the complement inhibitory factor H in rat Kupffer cells.

scientific article published in November 2004

Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger.

scientific article

Chronobiology of Melatonin beyond the Feedback to the Suprachiasmatic Nucleus-Consequences to Melatonin Dysfunction

scientific article published on 12 March 2013

Circadian rhythms, oxidative stress, and antioxidative defense mechanisms

scientific article published on November 2003

Depressive disorders: Processes leading to neurogeneration and potential novel treatments.

scientific article

Drug Insight: the use of melatonergic agonists for the treatment of insomnia-focus on ramelteon

scientific article published on April 2007

Effects of delta-aminolevulinic acid and melatonin in the harderian gland of female Syrian hamsters.

scientific article published in June 2002

Fine-tuning the amphiphilicity: a crucial parameter in the design of potent alpha-phenyl-N-tert-butylnitrone analogues

scientific article published on 25 July 2007

Fluorinated amphiphilic amino acid derivatives as antioxidant carriers: a new class of protective agents

scientific article published on 01 May 2006

Functional roles of melatonin in plants, and perspectives in nutritional and agricultural science ⬇️

scientific article published on October 20, 2011

Geschlechtsbedingte Unterschiede bei Tagesrhythmen von Insekten

scientific article published on 01 August 1969

Hydrogen therapy: a future option in critical care?

scientific article published in April 2012

Inflammaging, Metabolic Syndrome and Melatonin: A Call for Treatment Studies

scientific article published on 11 May 2016

Interactions of melatonin and its metabolites with the ABTS cation radical: extension of the radical scavenger cascade and formation of a novel class of oxidation products, C2-substituted 3-indolinones

scientific article published in November 2006

Investigational melatonin receptor agonists

scientific article published on June 2010

Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines

scientific article published on July 2009

Measurement of melatonin in body fluids: standards, protocols and procedures

scientific article

Mechanistic and comparative studies of melatonin and classic antioxidants in terms of their interactions with the ABTS cation radical.

scientific article published in May 2003

Melatonergic drugs in clinical practice

scientific article published on January 2008

Melatonin

scientific article published in 2006

Melatonin and Synthetic Melatoninergic Agonists in Psychiatric and Age-associated Disorders: Successful and Unsuccessful Approaches

scientific article published on 23 September 2014

Melatonin and brain inflammaging

scientific article

Melatonin and circadian oscillators in aging--a dynamic approach to the multiply connected players

scientific article

Melatonin and inflammation-Story of a double-edged blade

scientific article published on 12 October 2018

Melatonin and the electron transport chain

scientific article

Melatonin and the pathologies of weakened or dysregulated circadian oscillators

scientific article published on 20 October 2016

Melatonin and the theories of aging: a critical appraisal of melatonin's role in antiaging mechanisms

scientific article published on 23 September 2013

Melatonin antioxidative defense: therapeutical implications for aging and neurodegenerative processes

scientific article published on 28 June 2012

Melatonin as a candidate compound for neuroprotection in amyotrophic lateral sclerosis (ALS): high tolerability of daily oral melatonin administration in ALS patients

scientific article published in October 2002

Melatonin in aging and disease -multiple consequences of reduced secretion, options and limits of treatment ⬇️

scientific article published on February 10, 2011

Melatonin in macrophage biology: Current understanding and future perspectives

scientific article published on 21 January 2019

Melatonin in plants and other phototrophs: advances and gaps concerning the diversity of functions

scientific article

Melatonin metabolism in the central nervous system ⬇️

scientific article published on September 1, 2010

Melatonin overcomes MCR-mediated colistin resistance in Gram-negative pathogens

scientific article published on 29 August 2020

Melatonin protects against delta-aminolevulinic acid-induced oxidative damage in male Syrian hamster Harderian glands

scientific article published in May 2002

Melatonin receptor genes in vertebrates

scientific article published on 27 May 2013

Melatonin's unique radical scavenging properties - roles of its functional substituents as revealed by a comparison with its structural analogs

scientific article

Melatonin, a potent agent in antioxidative defense: actions as a natural food constituent, gastrointestinal factor, drug and prodrug

scientific article

Melatonin, noncoding RNAs, messenger RNA stability and epigenetics--evidence, hints, gaps and perspectives

scientific article

Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling.

scientific article published on 28 October 2011

Melatonin--a pleiotropic, orchestrating regulator molecule

scientific article published on 28 December 2010

Melatonin: a hormone, a tissue factor, an autocoid, a paracoid, and an antioxidant vitamin

scientific article

Melatonin: signaling mechanisms of a pleiotropic agent

scientific article published on March 2009

Mitochondrial medicine: neuroprotection and life extension by the new amphiphilic nitrone LPBNAH acting as a highly potent antioxidant agent.

scientific article published on 31 August 2005

NO scavenging by 3-hydroxyanthranilic acid and 3-hydroxykynurenine: N-nitrosation leads via oxadiazoles to o-quinone diazides

scientific article published on 17 July 2008

Neurobiology, Pathophysiology, and Treatment of Melatonin Deficiency and Dysfunction ⬇️

scientific article published on May 2, 2012

Neuroprotection by radical avoidance: search for suitable agents.

scientific article published on 07 December 2009

New approaches in the management of insomnia: weighing the advantages of prolonged-release melatonin and synthetic melatoninergic agonists

scientific article published on 10 June 2009

Non-vertebrate melatonin.

scientific article

Novel pathway for N1-acetyl-5-methoxykynuramine: UVB-induced liberation of carbon monoxide from precursor N1-acetyl-N2-formyl-5-methoxykynuramine

scientific article

On the Relationships between LncRNAs and Other Orchestrating Regulators: Role of the Circadian System

scientific article published on 31 May 2018

On the significance of an alternate pathway of melatonin synthesis via 5-methoxytryptamine: comparisons across species

scientific article published on 26 April 2016

Oxidation of melatonin by carbonate radicals and chemiluminescence emitted during pyrrole ring cleavage

scientific article

Pharmacotherapy of insomnia with ramelteon: safety, efficacy and clinical applications

scientific article published on 12 April 2011

Photocatalytic actions of the pesticide metabolite 2-hydroxyquinoxaline: destruction of antioxidant vitamins and biogenic amines - implications of organic redox cycling

scientific article published in January 2004

Photocatalytic mechanisms of indoleamine destruction by the quinalphos metabolite 2-hydroxyquinoxaline: a study on melatonin and its precursors serotonin and N-acetylserotonin

scientific article

Ramelteon: a review of its therapeutic potential in sleep disorders

scientific article published on 30 June 2009

Reactions of the NO redox forms NO+, *NO and HNO (protonated NO-) with the melatonin metabolite N1-acetyl-5-methoxykynuramine

scientific article published in November 2007

Reactions of the melatonin metabolite AMK (N1-acetyl-5-methoxykynuramine) with reactive nitrogen species: formation of novel compounds, 3-acetamidomethyl-6-methoxycinnolinone and 3-nitro-AMK.

scientific article

Reactions of the melatonin metabolite N(1)-acetyl-5-methoxykynuramine with carbamoyl phosphate and related compounds

scientific article published on 16 November 2009

Reactions of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK) with the ABTS cation radical: identification of new oxidation products

scientific article published on 01 January 2006

Reactions of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK) with the tyrosine side-chain fragment, 4-ethylphenol.

scientific article published in January 2008

Recent Findings in Melatonin Research and Their Relevance to the CNS

scientific article published on 01 January 2018

Reduced oxidative damage in ALS by high-dose enteral melatonin treatment

scientific article

Sleep, Melatonin, and the Menopausal Transition: What Are the Links?

scientific article published on January 2017

Sleep, melatonin, and the menopausal transition: What are the links?

retracted scientific article published in January 2017

Stunted Growth. Proceedings of the 23rd Aschauer Soiree, Held at Aschauhof, Germany, November 7th 2015.

scientific article

Targeting Host Defense System and Rescuing Compromised Mitochondria to Increase Tolerance against Pathogens by Melatonin May Impact Outcome of Deadly Virus Infection Pertinent to COVID-19

scientific article published on 25 September 2020

Tasimelteon, a melatonin agonist for the treatment of insomnia and circadian rhythm sleep disorders

scientific article

Taxon- and Site-Specific Melatonin Catabolism

scientific article

The changing biological roles of melatonin during evolution: from an antioxidant to signals of darkness, sexual selection and fitness

scientific article published on 21 December 2009

The melatonin metabolite N-acetyl-5-methoxykynuramine is a potent singlet oxygen scavenger

scientific article published on 28 June 2008

Therapeutic potential of melatonin and its analogs in Parkinson's disease: focus on sleep and neuroprotection

scientific article

Thymus-Pineal Gland Axis: Revisiting Its Role in Human Life and Ageing

scientific article published on 20 November 2020

Toxicity of the quinalphos metabolite 2-hydroxyquinoxaline: growth inhibition, induction of oxidative stress, and genotoxicity in test organisms

scientific article published in February 2007

When the circadian clock meets the melanin pigmentary system

scientific article published on April 2015

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