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List of works by Takashi Matsuzaka

A new perspective on type 2 diabetes, dyslipidemia, and non-alcoholic fatty liver disease

scientific article published on 30 March 2020

Ablation of Elovl6 protects pancreatic islets from high-fat diet-induced impairment of insulin secretion

scientific article published on 02 June 2014

Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr(-/-) mouse model

scientific article

CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα.

scientific article published on 16 December 2016

Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs.

scientific article

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of L

scientific article published in May 2003

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling

scientific article published on May 2003

Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance.

scientific article published on 30 September 2007

Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice

scientific article

Dual regulation of mouse Delta(5)- and Delta(6)-desaturase gene expression by SREBP-1 and PPARalpha

scientific article published in January 2002

Elovl6 Deficiency Improves Glycemic Control in Diabetic db/db Mice by Expanding β-Cell Mass and Increasing Insulin Secretory Capacity.

scientific article

Elovl6 promotes nonalcoholic steatohepatitis

scientific article published on 01 December 2012

Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice

scientific journal article

Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes.

scientific article published on 18 September 2014

Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system

scientific article published on 13 June 2016

Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice

scientific article published on 12 September 2011

Insulin-independent induction of sterol regulatory element-binding protein-1c expression in the livers of streptozotocin-treated mice

scientific article published in March 2004

Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression.

scientific article published on 17 September 2016

Macrophage Elovl6 Deficiency Ameliorates Foam Cell Formation and Reduces Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice

scientific article published on 04 August 2011

Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets

scientific article published on 5 May 2008

Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements

scientific article

Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver

scientific article published on 12 February 2007

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.

scientific article

SREBPs suppress IRS-2-mediated insulin signalling in the liver

scientific article published on 14 March 2004

Skeletal muscle-specific HMG-CoA reductase knockout mice exhibit rhabdomyolysis: A model for statin-induced myopathy

scientific article published on 14 September 2015

Sterol Regulatory Element–Binding Protein-1 Determines Plasma Remnant Lipoproteins and Accelerates Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

scientific article published on 05 May 2011

Sterol regulatory element-binding proteins activate insulin gene promoter directly and indirectly through synergy with BETA2/E47.

scientific article published on 29 July 2005

TFE3 controls lipid metabolism in adipose tissue of male mice by suppressing lipolysis and thermogenesis

scientific article published on 24 July 2013

TFE3 inhibits myoblast differentiation in C2C12 cells via down-regulating gene expression of myogenin.

scientific article published on 2 December 2012

TFE3 regulates muscle metabolic gene expression, increases glycogen stores, and enhances insulin sensitivity in mice

scientific article

TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes

scientific article published on 4 December 2005