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List of works by Eric O Aboagye

3'-Deoxy-3'-[(18)F]Fluorothymidine Uptake Is Related to Thymidine Phosphorylase Expression in Various Experimental Tumor Models

scientific article published on 2 October 2017

3'-deoxy-3'-[18F]fluorothymidine as a new marker for monitoring tumor response to antiproliferative therapy in vivo with positron emission tomography.

scientific article

3-D Microvascular Imaging Using High Frame Rate Ultrasound and ASAP Without Contrast Agents: Development and Initial In Vivo Evaluation on Nontumor and Tumor Models

scientific article published on 21 March 2019

3D Growth of Cancer Cells Elicits Sensitivity to Kinase Inhibitors but Not Lipid Metabolism Modifiers

scientific article published on 26 November 2018

A mathematical-descriptor of tumor-mesoscopic-structure from computed-tomography images annotates prognostic- and molecular-phenotypes of epithelial ovarian cancer

scientific article published in Nature Communications

A multifractal approach to space-filling recovery for PET quantification ⬇️

scientific article published in November 2014

A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration

scientific article

A novel small molecule hydroxamate preferentially inhibits HDAC6 activity and tumour growth ⬇️

scientific article published on January 15, 2013

A phantom for diffusion-weighted MRI (DW-MRI) ⬇️

scientific article published on April 10, 2013

AKT activation controls cell survival in response to HDAC6 inhibition

scientific article published on 30 June 2016

Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress

scientific article

Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas

scientific article

Altered cytochrome 2E1 and 3A P450-dependent drug metabolism in advanced ovarian cancer correlates to tumour-associated inflammation

scientific article published on 05 August 2019

An open-label study of lapatinib in women with HER-2-negative early breast cancer: the lapatinib pre-surgical study (LPS study) ⬇️

scientific article published on December 11, 2012

Anti-nicastrin monoclonal antibodies elicit pleiotropic anti-tumour pharmacological effects in invasive breast cancer cells

scientific article

Antibody Fragment and Affibody ImmunoPET Imaging Agents: Radiolabelling Strategies and Applications

scientific article published on 15 November 2018

Apparent Diffusion Coefficient of Normal Abdominal Organs and Bone Marrow From Whole-Body DWI at 1.5 T: The Effect of Sex and Age.

scientific article published in August 2015

Bioorthogonal chemistry for pre-targeted molecular imaging – progress and prospects ⬇️

scientific article published on September 21, 2013

Bioreductive metabolism of the novel fluorinated 2-nitroimidazole hypoxia probe N-(2-hydroxy-3, 3,3-trifluoropropyl)-2-(2-nitroimidazolyl) acetamide (SR-4554) ⬇️

scientific article published on 01 December 1997

Caspase-Based PET for Evaluating Pro-Apoptotic Treatments in a Tuberculosis Mouse Model

scientific article published on 30 March 2020

Clinical translation of [F]ICMT-11 for measuring chemotherapy-induced caspase 3/7 activation in breast and lung cancer

scientific article published on 27 September 2018

Clinical translation of molecular imaging agents used in PET studies of cancer

scientific article published on January 2014

Correction to: The relationship between endogenous thymidine concentrations and [18F]FLT uptake in a range of preclinical tumour models

scientific article published on 15 December 2017

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

scientific article published on October 2013

Design of symmetrical and nonsymmetrical N,N-dimethylaminopyridine derivatives as highly potent choline kinase alpha inhibitors

scientific article published on April 2013

Design, synthesis and in vitro characterization of fluorescent and paramagnetic CXCR4-targeted imaging agents ⬇️

scientific article published on July 10, 2013

Design, synthesis, and biological characterization of a caspase 3/7 selective isatin labeled with 2-[18F]fluoroethylazide

scientific article

Detecting hypoxia using F-pretargeted IEDDA "click" chemistry in live cells

scientific article

Development and Evaluation of an F-Radiolabeled Monocyclam Derivative for Imaging CXCR4 Expression

scientific article published on 03 April 2019

Development of 68Ga-labelled ultrasound microbubbles for whole-body PET imaging

scientific article published on 01 May 2019

Development of a cyclin-dependent kinase inhibitor devoid of ABC transporter-dependent drug resistance

scientific article

Development of a new epidermal growth factor receptor positron emission tomography imaging agent based on the 3-cyanoquinoline core: Synthesis and biological evaluation ⬇️

scientific article published on August 6, 2010

Development of radiotracers for oncology--the interface with pharmacology

scientific article

Discovery of pre-therapy 2-deoxy-2-F-fluoro-D-glucose positron emission tomography-based radiomics classifiers of survival outcome in non-small-cell lung cancer patients ⬇️

scientific article published on 01 September 2018

Double-input compartmental modeling and spectral analysis for the quantification of positron emission tomography data in oncology

scientific article

Efficacy of systemic temozolomide-activated phage-targeted gene therapy in human glioblastoma

article

Erratum to: Anti-nicastrin monoclonal antibodies elicit pleiotropic anti-tumour pharmacological effects in invasive breast cancer cells.

scientific article published on 28 October 2014

Erratum to: Lapatinib access into normal brain and brain metastases in patients with Her-2 overexpressing breast cancer

scientific article published on 8 September 2017

Evaluation of 18F-fluorothymidine positron emission tomography ([18F]FLT-PET/CT) methodology in assessing early response to chemotherapy in patients with gastro-oesophageal cancer

scientific article

Evaluation of Lactate as a 1 H Nuclear Magnetic Resonance Spectroscopy Index for Noninvasive Prediction and Early Detection of Tumor Response to Radiation Therapy in EMT6 Tumors

scientific article published on 01 July 1998

Evaluation of apoptosis imaging biomarkers in a genetic model of cell death

scientific article published on 19 February 2019

Evaluation of deuterated 18F- and 11C-labeled choline analogs for cancer detection by positron emission tomography.

scientific article published on 10 January 2012

Evaluation of limited blood sampling population input approaches for kinetic quantification of [18F]fluorothymidine PET data

scientific article

Exploiting altered patterns of choline kinase-alpha expression on human prostate tissue to prognosticate prostate cancer

scientific article published on 3 June 2015

Fluorescence enhancement from single gold nanostars: towards ultra-bright emission in the first and second near-infrared biological windows

scientific article published on 01 August 2018

Fully automatic, multiorgan segmentation in normal whole body magnetic resonance imaging (MRI), using classification forests (CFs), convolutional neural networks (CNNs), and a multi-atlas (MA) approach

scientific article

Functional imaging of hepatocellular carcinoma

scientific article published on 29 March 2016

Glucose metabolism measured by [¹⁸F]fluorodeoxyglucose positron emission tomography is independent of PTEN/AKT status in human colon carcinoma cells

scientific article

Guidelines for the welfare and use of animals in cancer research

scientific article

Identification of ABC Transporter Interaction of a Novel Cyanoquinoline Radiotracer and Implications for Tumour Imaging by Positron Emission Tomography

scientific article

Imaging biomarker roadmap for cancer studies ⬇️

scientific article

Imaging the life and death of tumors in living subjects: Preclinical PET imaging of proliferation and apoptosis ⬇️

scientific article published on August 25, 2010

Importance of quantification for the analysis of PET data in oncology: review of current methods and trends for the future

scientific article

Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments.

scientific article

Integrated analysis of multiple receptor tyrosine kinases identifies Axl as a therapeutic target and mediator of resistance to sorafenib in hepatocellular carcinoma

scientific article published on 15 February 2019

Intratumoral conversion of 5-fluorocytosine to 5-fluorouracil by monoclonal antibody-cytosine deaminase conjugates: noninvasive detection of prodrug activation by magnetic resonance spectroscopy and spectroscopic imaging ⬇️

scientific article published on September 15, 1998

Introduction to the analysis of PET data in oncology

scientific article

Iodination of terminal alkynes using KI/CuSO4 - A facile method with potential for radio-iodination.

scientific article published in March 2019

IκΒα inhibits apoptosis at the outer mitochondrial membrane independently of NF-κB retention.

scientific article

LARP1 post-transcriptionally regulates mTOR and contributes to cancer progression

scientific article published on 22 December 2014

Luciferase fragment complementation imaging in preclinical cancer studies

scientific article

Machine learning in whole-body MRI: experiences and challenges from an applied study using multicentre data

scientific article published on 23 February 2019

Metabolic activation of temozolomide measured in vivo using positron emission tomography ⬇️

scientific article published on May 15, 2003

Metabolically active tumour volume segmentation from dynamic [(18)F]FLT PET studies in non-small cell lung cancer

scientific article published on 23 April 2015

Microwave gallium-68 radiochemistry for kinetically stable bis(thiosemicarbazone) complexes: structural investigations and cellular uptake under hypoxia

scientific article published on 19 November 2015

Mn-salen catalysed benzylic C-H activation for the synthesis of aryl [(18)F]CF3-containing PET probes

scientific article published in May 2015

Molecular mechanisms of hypoxia in cancer

scientific article

Monitoring Early Response to Taxane Therapy in Advanced Breast Cancer with Circulating Tumor Cells and [ 18 F] 3´-deoxy-3´-Fluorothymidine PET: A Pilot Study ⬇️

scientific article published on April 1, 2012

New Frontiers in the Design and Synthesis of Imaging Probes for PET Oncology: Current Challenges and Future Directions ⬇️

scientific article published on December 1, 2012

Novel PET biomarkers for breast cancer imaging ⬇️

scientific article published on 01 May 2011

One-Pot Radiosynthesis and Biological Evaluation of a Caspase-3 Selective 5-[123,125I]iodo-1,2,3-triazole derived Isatin SPECT Tracer

scientific article published on 17 December 2019

PET for in vivo pharmacokinetic and pharmacodynamic measurements

scientific article

Parametric imaging of ¹⁸F-fluoro-3-deoxy-3-L-fluorothymidine PET data to investigate tumour heterogeneity.

scientific article

Pharmacokinetic evaluation of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide in patients by positron emission tomography

scientific article

Pharmacokinetics of radiolabelled anticancer drugs for positron emission tomography

scientific article

Phosphatidylcholine Metabolic Transformation and Progression Signature as a Pharmacodynamic Biomarker ⬇️

scientific article published on July 1, 2010

Phosphorylation status of thymidine kinase 1 following antiproliferative drug treatment mediates 3'-deoxy-3'-[18F]-fluorothymidine cellular retention

scientific article (publication date: 2014)

Positron Emission Tomography Imaging of Tumor Cell Metabolism and Application to Therapy Response Monitoring

scientific article

Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [18F]-labeled isatin sulfonamide

scientific article published on 3 September 2009

Preclinical Applications of 3'-Deoxy-3'-[18F]Fluorothymidine in Oncology - A Systematic Review

scientific article published on January 2017

Preclinical assessment of carboplatin treatment efficacy in lung cancer by 18F-ICMT-11-positron emission tomography

scientific article (publication date: 2014)

Preclinical development and current status of the fluorinated 2-nitroimidazole hypoxia probe N-(2-hydroxy-3,3,3-trifluoropropyl)-2-(2-nitro-1-imidazolyl) acetamide (SR 4554, CRC 94/17): a non-invasive diagnostic probe for the measurement of tumor hy

scientific article

Preclinical evaluation of 3-18F-fluoro-2,2-dimethylpropionic acid as an imaging agent for tumor detection

scientific article

Preclinical evaluation of the fluorinated 2-nitroimidazole N-(2-hydroxy-3,3,3-trifluoropropyl)-2-(2-nitro-1-imidazolyl) acetamide (SR-4554) as a probe for the measurement of tumor hypoxia ⬇️

scientific article published on 01 August 1997

Prediction of Deep Myometrial Infiltration, Clinical Risk Category, Histological Type, and Lymphovascular Space Invasion in Women with Endometrial Cancer Based on Clinical and T2-Weighted MRI Radiomic Features

scientific article published in 2023

Preliminary clinical assessment of the relationship between tumor alphavbeta3 integrin and perfusion in patients studied with [(18)F]fluciclatide kinetics and [ (15)O]H 2O PET.

scientific article published on 8 August 2014

RGD-targeted MnO nanoparticles as T1 contrast agents for cancer imaging - the effect of PEG length in vivo

scientific article published on 23 December 2013

Radiolabeled RGD tracer kinetics annotates differential αvβ 3 integrin expression linked to cell intrinsic and vessel expression

scientific article published on 6 December 2013

Radiolabelled Tracers and Anticancer Drugs for Assessment of Therapeutic Efficacy Using PET ⬇️

scientific article published on December 1, 2001

Radiolabelling an <sup>18</sup>F biologic <i>via</i> facile IEDDA “click” chemistry on the GE FASTLab™ platform

scientific article published in 2021

Radiological assessment of Peritoneal Cancer Index on preoperative CT in ovarian cancer is related to surgical outcome and survival

scientific article published on 01 April 2020

Radiosynthesis and in vivo tumor uptake of 2-deoxy-2-[18F]fluoro-myo-inositol ⬇️

scientific article published on August 11, 2012

Reliability of dynamic contrast-enhanced magnetic resonance imaging data in primary brain tumours: a comparison of Tofts and shutter speed models

scientific article published on 07 August 2019

Scavenging strategy for specific activity improvement: application to a new CXCR4-specific cyclopentapeptide positron emission tomography tracer

scientific article published on 16 July 2013

Small-animal imaging of tumour proliferation with PET.

scientific article published on February 2004

Synthesis and evaluation of 3'-[<sup>18</sup>F]fluorothymidine-5'-squaryl as a bioisostere of 3'-[<sup>18</sup>F]fluorothymidine-5'-monophosphate

scientific article published on 29 March 2021

Synthesis and evaluation of nucleoside radiotracers for imaging proliferation ⬇️

scientific article published on February 10, 2012

Temporal and Spatial Evolution of Therapy-Induced Tumor Apoptosis Detected by Caspase-3–Selective Molecular Imaging ⬇️

scientific article published on May 31, 2013

The HDAC6 inhibitor C1A modulates autophagy substrates in diverse cancer cells and induces cell death

scientific article published on 15 October 2018

The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis

scientific article

The development of a selective cyclin-dependent kinase inhibitor that shows antitumor activity

scientific article

The novel fluorinated 2-nitroimidazole hypoxia probe SR-4554: reductive metabolism and semiquantitative localisation in human ovarian cancer multicellular spheroids as measured by electron energy loss spectroscopic analysis ⬇️

scientific article published on August 1, 1995

The physiological environment in cancer vascularization, invasion and metastasis.

scientific article

The relationship between tumour oxygenation determined by oxygen electrode measurements and magnetic resonance spectroscopy of the fluorinated 2-nitroimidazole SR-4554 ⬇️

scientific article published on January 1, 1998

Towards an MMP-2-activated molecular agent for cancer imaging

scientific article published on 10 January 2018

Towards multiplexed near-infrared cellular imaging using gold nanostar arrays with tunable fluorescence enhancement

scientific article published on 01 January 2019

Tracing Nutrient Flux Following Monocarboxylate Transporter-1 Inhibition with AZD3965

scientific article published on 26 June 2020

Use of positron emission tomography in anticancer drug development

scientific article

Visualising androgen receptor activity in male and female mice

scientific article

[18F]Fluciclatide PET as a biomarker of response to combination therapy of pazopanib and paclitaxel in platinum-resistant/refractory ovarian cancer

scientific article published on 21 November 2019

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