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List of works by Tarjei S Mikkelsen

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

scientific article (publication date: 21 April 2006)

A distant trophoblast-specific enhancer controls HLA-G expression at the maternal-fetal interface

scientific article published on 13 April 2016

A human-specific gene in microglia.

scientific article published in September 2005

A second fatty acid amide hydrolase with variable distribution among placental mammals

scientific article

A unique regulatory phase of DNA methylation in the early mammalian embryo ⬇️

scientific article published on March 28, 2012

Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome

scientific article published on 05 September 2018

Altered chromatin occupancy of master regulators underlies evolutionary divergence in the transcriptional landscape of erythroid differentiation

scientific article published on 18 December 2014

Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling

scientific article

Brief report: importance of SOX8 for in vitro chondrogenic differentiation of human mesenchymal stromal cells.

scientific article

Cellular source and mechanisms of high transcriptome complexity in the mammalian testis

scientific article published on 20 June 2013

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

scientific article (publication date: 12 March 2009)

Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing

scientific article published on 30 March 2020

Comparative Epigenomic Analysis of Murine and Human Adipogenesis ⬇️

scientific article published on October 1, 2010

Comprehensive mutational scanning of a kinase in vivo reveals substrate-dependent fitness landscapes

scientific article published on 9 June 2014

Convergent and divergent evolution of genomic imprinting in the marsupial Monodelphis domestica

scientific article

DNA sequence and analysis of human chromosome 18

scientific article

DNA sequence and analysis of human chromosome 8

scientific article

Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN

scientific article published in Science

Direct Identification of Hundreds of Expression-Modulating Variants using a Multiplexed Reporter Assay

scientific article

Direct Identification of Hundreds of Expression-Modulating Variants using a Multiplexed Reporter Assay

scientific article published on 01 February 2018

Dissecting neural differentiation regulatory networks through epigenetic footprinting

scientific article published on 24 December 2014

Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells

scientific article

Early B-cell factor-1 (EBF1) is a key regulator of metabolic and inflammatory signaling pathways in mature adipocytes

scientific article published on 30 October 2013

Enhanced methods for unbiased deep sequencing of Lassa and Ebola RNA viruses from clinical and biological samples

scientific article

Erratum: Corrigendum: DNA sequence and analysis of human chromosome 18

scientific article published in Nature

FOSL2 promotes leptin gene expression in human and mouse adipocytes

scientific article published on 13 February 2012

Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

scientific article

Genome sequence, comparative analysis and haplotype structure of the domestic dog

scientific article

Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution

scientific article published on 10 January 2010

Genome-scale DNA methylation maps of pluripotent and differentiated cells

scientific article

Genome-scale high-resolution mapping of activating and repressive nucleotides in regulatory regions

scientific article published on 3 October 2016

Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells

scientific article

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

scientific article

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

scientific article published in October 2008

High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosis

scientific article

Identification of Functional Variants in the FAM13A Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Locus by Massively Parallel Reporter Assays

scientific article published on 01 January 2019

Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis.

scientific article

Improving genome annotations using phylogenetic profile anomaly detection

scientific article

Initial sequencing and analysis of the human genome

scientific article published on 15 February 2001

Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency

scientific article published in July 2015

Integrative genomics identifies the corepressor SMRT as a gatekeeper of adipogenesis through the transcription factors C/EBPβ and KAISO.

scientific article published on 19 April 2012

Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity

scientific article published in July 2017

LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency

scientific article

Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci

scientific article published in April 2017

Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression

scientific article published on 12 September 2019

Massively parallel digital transcriptional profiling of single cells

scientific article

Massively parallel reporter assays in cultured mammalian cells

scientific article

Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning

scientific article

Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal

scientific article

Open source handheld-based EMR for paramedics working in rural areas.

scientific article

Organism-Level Analysis of Vaccination Reveals Networks of Protection across Tissues.

scientific article published on 4 September 2017

Parallel derivation of isogenic human primed and naive induced pluripotent stem cells

scientific article published on 24 January 2018

Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites

scientific article

Phenotypic Characterization of a Comprehensive Set of MAPK1/ERK2 Missense Mutants

scientific article published on October 2016

Progenitor identification and SARS-CoV-2 infection in human distal lung organoids

scientific article published on 25 November 2020

Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures

scientific article published on 27 July 2020

Prospective functional classification of all possible missense variants in PPARG.

scientific article published on 17 October 2016

Registry in a tube: multiplexed pools of retrievable parts for genetic design space exploration

scientific article published on 01 February 2017

Registry in a tube: multiplexed pools of retrievable parts for genetic design space exploration.

scientific article

Simultaneous Pathway Activity Inference and Gene Expression Analysis Using RNA Sequencing

scientific article published on 19 May 2016

Solving nonlinear polynomial systems in the barycentric Bernstein basis

System-wide genomic and biochemical comparisons of sialic acid biology among primates and rodents: Evidence for two modes of rapid evolution

scientific article published on 12 June 2006

Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits

scientific article

Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites

scientific article

Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay

scientific article

Systematic dissection of genomic features determining transcription factor binding and enhancer function

scientific article published on 30 January 2017

Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay

scientific article published on 19 March 2013

The DAILY (Daily Automated Intensive Log for Youth) trial: a wireless, portable system to improve adherence and glycemic control in youth with diabetes

scientific article

The NIH Roadmap Epigenomics Mapping Consortium

scientific article (publication date: October 2010)

The case for selection at CCR5-Delta32

scientific article published in November 2005

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

scientific article published on 23 March 2014

The regulatory landscape of osteogenic differentiation

scientific article published in October 2014

What makes us human?

scientific article

ZBED6 modulates the transcription of myogenic genes in mouse myoblast cells

scientific article

ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth

scientific article

microRNA-140 targets RALA and regulates chondrogenic differentiation of human mesenchymal stem cells by translational enhancement of SOX9 and ACAN.

scientific article published on 7 November 2013

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