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List of works by Aikaterini Kontrogianni-Konstantopoulos

A microfluidic assay for the quantification of the metastatic propensity of breast cancer specimens

scientific article published on 06 May 2019

Advances in Muscle Physiology and Pathophysiology ⬇️

scientific article published on July 27, 2010

Advances in Muscle Physiology and Pathophysiology 2011 ⬇️

scientific article published on January 15, 2012

Array lessons from the heart: focus on the genome and transcriptome of cardiomyopathies

scientific article

Characterization and Comparison of Two Binding Sites on Obscurin for Small Ankyrin 1 ⬇️

scientific article published on November 23, 2010

Competition through dimerization between antiapoptotic and proapoptotic HS-1-associated protein X-1 (Hax-1).

scientific article published on 17 December 2013

Correction: Obscurins: Goliaths and Davids Take over Non-Muscle Tissues

scientific article published on 3 January 2018

Corrigendum: The Phosphorylation Profile of Myosin Binding Protein-C Slow is Dynamically Regulated in Slow-Twitch Muscles in Health and Disease.

scientific article published on 11 May 2018

De novo myofibrillogenesis in C2C12 cells: evidence for the independent assembly of M bands and Z disks

scientific article published on 5 October 2005

Deletion of obscurin immunoglobulin domains Ig58/59 leads to age-dependent cardiac remodeling and arrhythmia

scientific article published on 10 September 2020

Deregulated Ca2+ cycling underlies the development of arrhythmia and heart disease due to mutant obscurin

scientific article

Different obscurin isoforms localize to distinct sites at sarcomeres

scientific article

Double the trouble: giant proteins with dual kinase activity in the heart

scientific article published on 08 July 2020

Dynamics of obscurin localization during differentiation and remodeling of cardiac myocytes: obscurin as an integrator of myofibrillar structure

scientific article

Electrostatic interactions mediate binding of obscurin to small ankyrin 1: biochemical and molecular modeling studies.

scientific article

Essential role of obscurin in cardiac myofibrillogenesis and hypertrophic response: evidence from small interfering RNA-mediated gene silencing.

scientific article

Giant obscurins regulate the PI3K cascade in breast epithelial cells via direct binding to the PI3K/p85 regulatory subunit

scientific article published on 13 June 2016

HAX-1: A multifaceted antiapoptotic protein localizing in the mitochondria and the sarcoplasmic reticulum of striated muscle cells

scientific article published on 11 November 2009

HAX‐1: A family of apoptotic regulators in health and disease ⬇️

scientific article published on November 1, 2011

Heterozygous variants in MYBPC1 are associated with an expanded neuromuscular phenotype beyond arthrogryposis

scientific article published on 05 May 2019

Histidine-rich Ca-binding protein interacts with sarcoplasmic reticulum Ca-ATPase

scientific article

Integrity of the network sarcoplasmic reticulum in skeletal muscle requires small ankyrin 1 ⬇️

scientific article published on November 1, 2011

Loss of actomyosin regulation in distal arthrogryposis myopathy due to mutant myosin binding protein‐C slow ⬇️

scientific article published on May 8, 2013

Loss of giant obscurins alters breast epithelial cell mechanosensing of matrix stiffness

scientific article published on August 2016

Loss of giant obscurins promotes breast epithelial cell survival through apoptotic resistance ⬇️

scientific article published on March 21, 2012

Loss of the obscurin-RhoGEF downregulates RhoA signaling and increases microtentacle formation and attachment of breast epithelial cells

scientific article

MYBPC1, an Emerging Myopathic Gene: What We Know and What We Need to Learn

scientific article

Mapping the binding site on small ankyrin 1 for obscurin

scientific article

Muscle giants: molecular scaffolds in sarcomerogenesis

scientific article

Myosin Binding Protein-C Slow Phosphorylation is Altered in Duchenne Dystrophy and Arthrogryposis Myopathy in Fast-Twitch Skeletal Muscles

scientific article

Myosin Binding Protein-C Slow is a Novel Substrate for Protein Kinase A (PKA) and C (PKC) in Skeletal Muscle ⬇️

scientific article published on September 22, 2011

Myosin Binding Protein‐C: A Regulator of Actomyosin Interaction in Striated Muscle ⬇️

scientific article published on October 16, 2011

Myosin binding protein-C slow: a multifaceted family of proteins with a complex expression profile in fast and slow twitch skeletal muscles

scientific article published on 25 December 2013

Myosin binding protein-C slow: an intricate subfamily of proteins

scientific article

Novel mutations in MYBPC1 are associated with myogenic tremor and mild myopathy

scientific article published on 17 May 2019

Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway

scientific article published on 4 August 2017

Obscurin interacts with a novel isoform of MyBP-C slow at the periphery of the sarcomeric M-band and regulates thick filament assembly

scientific article published on 29 April 2009

Obscurin is a ligand for small ankyrin 1 in skeletal muscle

scientific article

Obscurin is required for the lateral alignment of striated myofibrils in zebrafish.

scientific article published in August 2006

Obscurin modulates the assembly and organization of sarcomeres and the sarcoplasmic reticulum

scientific journal article

Obscurin regulates the organization of myosin into A bands

scientific article

Obscurin: a multitasking muscle giant

scientific journal article

Obscurins: Goliaths and Davids take over non-muscle tissues

scientific article

Obscurins: Unassuming giants enter the spotlight ⬇️

scientific article published on March 20, 2013

Phospholamban interacts with HAX-1, a mitochondrial protein with anti-apoptotic function

scientific article published on 21 October 2006

Proteomic Analysis of Myocardia Containing the Obscurin R4344Q Mutation Linked to Hypertrophic Cardiomyopathy

scientific article published on 18 May 2020

Rapid response of cardiac obscurin gene cluster to aortic stenosis: differential activation of Rho-GEF and MLCK and involvement in hypertrophic growth ⬇️

scientific article published on October 24, 2003

Regulation of myofilament force and loaded shortening by skeletal myosin binding protein C

scientific article published on 31 January 2019

Resisting resistin; it's good for the heart ⬇️

scientific article published on May 24, 2011

Sarcomeric myopathies associated with tremor: new insights and perspectives

scientific article published on 16 October 2019

Structure before function: myosin binding protein-C slow is a structural protein with regulatory properties

scientific article published on 06 June 2018

The Phosphorylation Profile of Myosin Binding Protein-C Slow is Dynamically Regulated in Slow-Twitch Muscles in Health and Disease.

scientific article

The Ser96Ala variant in histidine-rich calcium-binding protein is associated with life-threatening ventricular arrhythmias in idiopathic dilated cardiomyopathy

scientific article

The anti-apoptotic protein HAX-1 interacts with SERCA2 and regulates its protein levels to promote cell survival

scientific article published on 29 October 2008

The anti-apoptotic protein HAX-1 is a regulator of cardiac function

scientific journal article

The hydrophilic domain of small ankyrin-1 interacts with the two N-terminal immunoglobulin domains of titin

scientific article

The kinase domains of obscurin interact with intercellular adhesion proteins

scientific journal article

The rho-guanine nucleotide exchange factor domain of obscurin regulates assembly of titin at the Z-disk through interactions with Ran binding protein 9

scientific article published on 25 June 2008

The sarcomeric M-region: a molecular command center for diverse cellular processes

scientific article published on 15 April 2015

Thick Filament Protein Network, Functions, and Disease Association

scientific article published on 13 March 2018

Unraveling obscurins in heart disease

scientific article published on 11 August 2018

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