List of works - Christopher A Lazarski

A population of innate myelolymphoblastoid effector cell expanded by inactivation of mTOR complex 1 in mice.

scientific article published on 5 December 2017

A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy

scientific article published on 22 February 2018

An aptamer-based targeted delivery of miR-26a protects mice against chemotherapy toxicity while suppressing tumor growth

scientific article published on 22 June 2017

Antiviral T-Cells for Adenovirus in the Pre-Transplant Period: a Bridge Therapy for Severe Combined Immunodeficiency.

scientific article

Critical requirement for the Wiskott-Aldrich syndrome protein in Th2 effector function

scientific article

Direct ex vivo analyses of HLA-DR1 transgenic mice reveal an exceptionally broad pattern of immunodominance in the primary HLA-DR1-restricted CD4 T-cell response to influenza virus hemagglutinin

scientific article

High-Intensity Focused Ultrasound (HIFU) Triggers Immune Sensitization of Refractory Murine Neuroblastoma to Checkpoint Inhibitor Therapy

scientific article published on 15 October 2019

IL-4 attenuates Th1-associated chemokine expression and Th1 trafficking to inflamed tissues and limits pathogen clearance

scientific article

Identification of new cytokine combinations for antigen-specific T-cell therapy products via a high-throughput multi-parameter assay

scientific article published on 10 September 2020

Immunodominance in CD4 T-cell responses: implications for immune responses to influenza virus and for vaccine design

scientific article published on June 2007

Immunodominance of CD4 T cells to foreign antigens is peptide intrinsic and independent of molecular context: implications for vaccine design

scientific article published on September 2008

Profiling the Targets of Protective CD8+ T Cell Responses to Infection

scientific article published on 18 August 2017

Regulating Treg cells at sites of inflammation

scientific article published on 01 October 2008

Regulation of immunity at tissue sites of inflammation

scientific article published on 31 January 2009

T-Cell Therapeutics Targeting Human Parainfluenza Virus 3 Are Broadly Epitope Specific and Are Cross Reactive With Human Parainfluenza Virus 1

scientific article published on 05 October 2020

T-cell receptor sequencing demonstrates persistence of virus-specific T cells after antiviral immunotherapy

scientific article published on 20 June 2019

The impact of DM on MHC class II-restricted antigen presentation can be altered by manipulation of MHC-peptide kinetic stability

scientific article

The kinetic stability of MHC class II:peptide complexes is a key parameter that dictates immunodominance

scientific article published on 01 July 2005

The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes

scientific article

Transcriptomic analysis reveals optimal cytokine combinations for SARS-CoV-2-specific T cell therapy products

scientific article published on 29 April 2022

List of works by Christopher A Lazarski

A population of innate myelolymphoblastoid effector cell expanded by inactivation of mTOR complex 1 in mice.

A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy

An aptamer-based targeted delivery of miR-26a protects mice against chemotherapy toxicity while suppressing tumor growth

Antiviral T-Cells for Adenovirus in the Pre-Transplant Period: a Bridge Therapy for Severe Combined Immunodeficiency.

Critical requirement for the Wiskott-Aldrich syndrome protein in Th2 effector function

Direct ex vivo analyses of HLA-DR1 transgenic mice reveal an exceptionally broad pattern of immunodominance in the primary HLA-DR1-restricted CD4 T-cell response to influenza virus hemagglutinin

High-Intensity Focused Ultrasound (HIFU) Triggers Immune Sensitization of Refractory Murine Neuroblastoma to Checkpoint Inhibitor Therapy

IL-4 attenuates Th1-associated chemokine expression and Th1 trafficking to inflamed tissues and limits pathogen clearance

Identification of new cytokine combinations for antigen-specific T-cell therapy products via a high-throughput multi-parameter assay

Immunodominance in CD4 T-cell responses: implications for immune responses to influenza virus and for vaccine design

Immunodominance of CD4 T cells to foreign antigens is peptide intrinsic and independent of molecular context: implications for vaccine design

Profiling the Targets of Protective CD8+ T Cell Responses to Infection

Regulating Treg cells at sites of inflammation

Regulation of immunity at tissue sites of inflammation

T-Cell Therapeutics Targeting Human Parainfluenza Virus 3 Are Broadly Epitope Specific and Are Cross Reactive With Human Parainfluenza Virus 1

T-cell receptor sequencing demonstrates persistence of virus-specific T cells after antiviral immunotherapy

The impact of DM on MHC class II-restricted antigen presentation can be altered by manipulation of MHC-peptide kinetic stability

The kinetic stability of MHC class II:peptide complexes is a key parameter that dictates immunodominance

The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes

Transcriptomic analysis reveals optimal cytokine combinations for SARS-CoV-2-specific T cell therapy products