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List of works by Tuomo Laitinen

1,2,6-Thiadiazinones as Novel Narrow Spectrum Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) Inhibitors.

scientific article

Assessment of mutation probabilities of KRAS G12 missense mutants and their long-timescale dynamics by atomistic molecular simulations and Markov state modeling

scientific article published on 10 September 2018

Comparative and pharmacophore model for deacetylase SIRT1

scientific article published on 01 September 2006

DPD-Inspired Discovery of Novel LsrK Kinase Inhibitors: An Opportunity To Fight Antimicrobial Resistance

scientific article published on 04 March 2019

Design and Analysis of the 4-Anilinoquin(az)oline Kinase Inhibition Profiles of GAK/SLK/STK10 Using Quantitative Structure-Activity Relationships

scientific article published on 26 November 2019

Design of a Cyclin G Associated Kinase (GAK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Set to Interrogate the Relationship of EGFR and GAK in Chordoma

scientific article published on 19 April 2019

Development of Pharmacophore Model for Indeno[1,2-b]indoles as Human Protein Kinase CK2 Inhibitors and Database Mining

scientific article published on 9 January 2017

Identification of Key Amino Acids that Impact Organic Solute Transporter <i>α</i>/<i>β</i> (OSTα/β)

scientific article published on 01 October 2021

Identification of novel SIRT3 inhibitor scaffolds by virtual screening

scientific article published on 16 March 2013

In Vitro and in Silico Evaluation of Bikaverin as a Potent Inhibitor of Human Protein Kinase CK2

scientific article published on 08 April 2019

Integrative and personalized QSAR analysis in cancer by kernelized Bayesian matrix factorization

scientific article

Investigation of the Pentathiepin Functionality as an Inhibitor of Feline Immunodeficiency Virus (FIV) via a Potential Zinc Ejection Mechanism, as a Model for HIV Infection

scientific article published on 25 January 2019

MM-PBSA free energy analysis of endo-1,4-xylanase II (XynII)–substrate complexes: binding of the reactive sugar in a skew boat and chair conformation ⬇️

scientific article published on October 21, 2003

New Insights into 4-Anilinoquinazolines as Inhibitors of Cardiac Troponin I-Interacting Kinase (TNNi3K)

scientific article published on 07 April 2020

Novel epidithiodiketopiperazines as anti-viral zinc ejectors of the Feline Immunodeficiency Virus (FIV) nucleocapsid protein as a model for HIV infection

scientific article published on 30 July 2019

Peptides and Pseudopeptides as SIRT6 Deacetylation Inhibitors

scientific article

Quinazoline-Based Antivirulence Compounds Selectively Target Salmonella PhoP/PhoQ Signal Transduction System

scientific article published on 20 December 2019

SARS-CoV-2-host proteome interactions for antiviral drug discovery

scientific article published on 01 November 2021

Structure-Based Virtual Screening of LsrK Kinase Inhibitors to Target Quorum Sensing

scientific article published on 30 October 2018

Structure-function analysis indicates that sumoylation modulates DNA-binding activity of STAT1.

scientific article

Synthesis and comparison of substituted 1,2,3-dithiazole and 1,2,3-thiaselenazole as inhibitors of the feline immunodeficiency virus (FIV) nucleocapsid protein as a model for HIV infection

scientific article published on 09 May 2019

Targeting an EGFR Water Network with 4-Anilinoquin(az)oline Inhibitors for Chordoma

scientific article published on 23 September 2019

The Effects of Sequence Variation on Genome-wide NRF2 Binding--New Target Genes and Regulatory SNPs

scientific article

Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis.

scientific article published on 23 September 2015

Towards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK)

scientific article published on 06 November 2019

Whole grain intake associated molecule 5-aminovaleric acid betaine decreases β-oxidation of fatty acids in mouse cardiomyocytes

scientific article published in Scientific Reports

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