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Authors whose works are in public domain in at least one jurisdiction

List of works by Robert Häsler

A combined epigenome- and transcriptome-wide association study of the oral masticatory mucosa assigns CYP1B1 a central role for epithelial health in smokers

scientific article published on 22 July 2019

A functional EXO1 promoter variant is associated with prolonged life expectancy in centenarians

scientific article published on 19 August 2009

A functional methylome map of ulcerative colitis

scientific article

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

scientific article (publication date: February 2007)

A model of cigarette smoke induced COPD identifies Nrf2 signaling as an expedient target for intervention

scientific article published on 01 August 2018

A tissue-specific landscape of sense/antisense transcription in the mouse intestine

scientific article

ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING

scientific article published on 25 September 2018

Alterations of pre-mRNA splicing in human inflammatory bowel disease

article

Analysis of NOD2-mediated proteome response to muramyl dipeptide in HEK293 cells

scientific article published on 28 October 2005

Anti-TNF-α antibodies improve intestinal barrier function in Crohn's disease

article

Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies

scientific article published on 25 April 2013

Atopobium and Fusobacterium as novel candidates for sarcoidosis-associated microbiota

scientific article published on 14 December 2017

Cell-autonomous hepatocyte-specific GP130 signalling is sufficient to trigger a robust innate immune response in mice

scientific article published on 25 September 2020

Characteristic changes in microbial community composition and expression of innate immune genes in acute appendicitis.

scientific article

Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype

scientific article published on 8 November 2011

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

scientific article

DNA methylation QTL analysis identifies new regulators of human longevity

scientific article published on 11 March 2020

DNA methylation analysis in nonalcoholic fatty liver disease suggests distinct disease-specific and remodeling signatures after bariatric surgery

scientific article published on August 2013

Decreased sigmoidal ABCB1 (P-glycoprotein) expression in ulcerative colitis is associated with disease activity.

scientific article

Disease-associated miRNA-mRNA networks in oral lichen planus.

scientific article

Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays

scientific article

Downregulation of TRAIL-Receptor 1 Increases TGFβ Type II Receptor Expression and TGFβ Signalling Via MicroRNA-370-3p in Pancreatic Cancer Cells

scientific article published on 25 October 2018

Epigenetics of Inflammatory Bowel Disease

article

Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation

scientific article

From model cell line to in vivo gene expression: disease-related intestinal gene expression in IBD.

scientific article

G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation

scientific article published on 16 November 2009

Gene expression analysis in untreated absence epilepsy demonstrates an inconsistent pattern

scientific article published on 28 February 2017

Gene expression profiling of head and neck squamous cell carcinoma using cDNA microarrays.

scientific article

Genetic control of global gene expression levels in the intestinal mucosa: a human twin study

scientific article published on 10 March 2009

Genetic interplay between human longevity and metabolic pathways - a large-scale eQTL study

scientific article published on 19 April 2017

Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.

scientific article

Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).

scientific article

Genome-wide expression profiling identifies an impairment of negative feedback signals in the Crohn's disease-associated NOD2 variant L1007fsinsC.

scientific article published on 18 February 2011

Genome-wide rare copy number variation screening in ulcerative colitis identifies potential susceptibility loci.

scientific article

Host-Microbe Interactions in the Chemosynthetic Riftia pachyptila Symbiosis

scientific article published on 17 December 2019

Identification and characterization of two functional variants in the human longevity gene FOXO3.

scientific article published on 12 December 2017

Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases

scientific article

Increased intestinal permeability and tight junction disruption by altered expression and localization of occludin in a murine graft versus host disease model

scientific article published on 06 October 2011

Initial symbiont contact orchestrates host-organ-wide transcriptional changes that prime tissue colonization

scientific article published on August 2013

Linear isoforms of the long noncoding RNA CDKN2B-AS1 regulate the c-myc-enhancer binding factor RBMS1

scientific article published on 14 August 2018

Metastasis of pancreatic cancer: An uninflamed liver micromilieu controls cell growth and cancer stem cell properties by oxidative phosphorylation in pancreatic ductal epithelial cells

scientific article published on 28 March 2019

Microbial pattern recognition causes distinct functional micro-RNA signatures in primary human monocytes

scientific article (publication date: 2012)

NOD2 influences trajectories of intestinal microbiota recovery after antibiotic perturbation

scientific article published on 11 April 2020

Nod2 is essential for temporal development of intestinal microbial communities.

scientific article

Non-response to antiepileptic pharmacotherapy is associated with the ABCC2 -24C>T polymorphism in young and adult patients with epilepsy.

scientific article published in May 2009

Nuclear death receptor TRAIL-R2 inhibits maturation of let-7 and promotes proliferation of pancreatic and other tumor cells

scientific article

On a Western diet, APOEɛ4 is associated with low innate immune sensing, but not APOEɛ3

scientific article published on 19 June 2018

Oral glutamine supplementation improves intestinal permeability dysfunction in a murine acute graft-vs.-host disease model

scientific article published on 31 January 2013

Peri-implantitis versus periodontitis: functional differences indicated by transcriptome profiling

scientific article published on 11 September 2012

Publisher Correction: Identification and characterization of two functional variants in the human longevity gene FOXO3.

scientific article published on 17 January 2018

RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition

scientific article published on 3 December 2012

Role of CCL20 mediated immune cell recruitment in NF-κB mediated TRAIL resistance of pancreatic cancer

scientific article published on 7 February 2017

SETDB1 is required for intestinal epithelial differentiation and the prevention of intestinal inflammation

scientific article published on 05 June 2020

Systematic association mapping identifies NELL1 as a novel IBD disease gene

scientific article published in 2007

Targeting gene expression during the early bone healing period in the mandible: A base for bone tissue engineering.

scientific article published on 23 June 2015

Tethering soluble meprin α in an enzyme complex to the cell surface affects IBD-associated genes

scientific article published on 27 March 2019

The antibiotic resistome and microbiota landscape of refugees from Syria, Iraq and Afghanistan in Germany.

scientific article published on 20 February 2018

The large non-coding RNA ANRIL, which is associated with atherosclerosis, periodontitis and several forms of cancer, regulates ADIPOR1, VAMP3 and C11ORF10.

scientific article published on 27 June 2013

The level of secretory leukocyte protease inhibitor is decreased in metastatic head and neck squamous cell carcinoma

scientific article

The nucleotide-binding oligomerization domain-like receptor NLRC5 is involved in IFN-dependent antiviral immune responses

scientific article

Transcriptome and genome sequencing uncovers functional variation in humans

scientific article

Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis

scientific article

Two different epigenetic information channels in wild three-spined sticklebacks are involved in salinity adaptation

scientific article published on 20 March 2020

Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease.

scientific article

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