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List of works by Marjolijn N Lub-de Hooge

(111)In-trastuzumab scintigraphy in HER2-positive metastatic breast cancer patients remains feasible during trastuzumab treatment.

scientific article

(89)Zr-trastuzumab PET visualises HER2 downregulation by the HSP90 inhibitor NVP-AUY922 in a human tumour xenograft

scientific article

89Zr-Bevacizumab PET Visualizes Disease Manifestations in Patients with von Hippel-Lindau Disease.

scientific article published on 12 May 2016

89Zr-Bevacizumab PET: Potential Early Indicator of Everolimus Efficacy in Patients with Metastatic Renal Cell Carcinoma

scientific article published on 12 January 2017

89Zr-Lumretuzumab PET Imaging before and during HER3 Antibody Lumretuzumab Treatment in Patients with Solid Tumors.

scientific article published on 21 July 2017

89Zr-Onartuzumab PET imaging of c-MET receptor dynamics.

scientific article

89Zr-atezolizumab imaging as a non-invasive approach to assess clinical response to PD-L1 blockade in cancer

scientific article published on 26 November 2018

89Zr-bevacizumab PET imaging in primary breast cancer

scientific article published on 7 May 2013

89Zr-bevacizumab PET of early antiangiogenic tumor response to treatment with HSP90 inhibitor NVP-AUY922.

scientific article published on 15 April 2010

89Zr-bevacizumab PET visualizes heterogeneous tracer accumulation in tumor lesions of renal cell carcinoma patients and differential effects of antiangiogenic treatment.

scientific article published on 4 December 2014

89Zr-mAb3481 PET for HER3 tumor status assessment during lapatinib treatment

scientific article

89Zr-pembrolizumab biodistribution is influenced by PD-1-mediated uptake in lymphoid organs

scientific article published on 01 October 2020

89Zr-trastuzumab and 89Zr-bevacizumab PET to evaluate the effect of the HSP90 inhibitor NVP-AUY922 in metastatic breast cancer patients.

scientific article

Albumin-binding and tumor vasculature determine the antitumor effect of 15-deoxy-Delta-(12,14)-prostaglandin-J(2) in vivo

scientific article published on December 2009

Antibody positron emission tomography imaging in anticancer drug development.

scientific article published on 16 March 2015

Application of (99m)Technetium-HYNIC(tricine/TPPTS)-Aca-Bombesin(7-14) SPECT/CT in prostate cancer patients: a first-in-man study

scientific article published on 26 July 2013

Bevacizumab-induced normalization of blood vessels in tumors hampers antibody uptake

scientific article published on 11 April 2013

Biodistribution and PET Imaging of Labeled Bispecific T Cell-Engaging Antibody Targeting EpCAM.

scientific article published on 4 February 2016

Chemical modification of interleukin-10 with mannose 6-phosphate groups yields a liver-selective cytokine

scientific article published on 20 February 2007

Clinical validation of the analysis of fluconazole in oral fluid in hospitalized children

scientific article

Comparative biodistribution analysis across four different Zr-monoclonal antibody tracers-The first step towards an imaging warehouse

scientific article published on 30 July 2018

Development and characterization of clinical-grade 89Zr-trastuzumab for HER2/neu immunoPET imaging

scientific article

Development, preclinical safety, formulation, and stability of clinical grade bevacizumab-800CW, a new near infrared fluorescent imaging agent for first in human use

scientific article published on 12 May 2016

Enhanced antitumor efficacy of a DR5-specific TRAIL variant over recombinant human TRAIL in a bioluminescent ovarian cancer xenograft model.

scientific article published on 10 March 2009

Everolimus Reduces (89)Zr-Bevacizumab Tumor Uptake in Patients with Neuroendocrine Tumors

scientific article published on 01 May 2014

Extracellular domain shedding influences specific tumor uptake and organ distribution of the EGFR PET tracer 89Zr-imgatuzumab

scientific article published on 02 September 2016

Feasibility of vascular endothelial growth factor imaging in human atherosclerotic plaque using (89)Zr-bevacizumab positron emission tomography

scientific article published in June 2013

Harnessing Integrative Omics to Facilitate Molecular Imaging of the Human Epidermal Growth Factor Receptor Family for Precision Medicine.

scientific article

Human Epidermal Growth Factor Receptor 3-Specific Tumor Uptake and Biodistribution of 89Zr-MSB0010853 Visualized by Real-Time and Noninvasive PET Imaging

scientific article

Imaging the distribution of an antibody-drug conjugate constituent targeting mesothelin with ⁸⁹Zr and IRDye 800CW in mice bearing human pancreatic tumor xenografts.

scientific article published on 29 October 2015

Immuno-PET: a navigator in monoclonal antibody development and applications.

scientific article published on December 2007

ImmunoPET and biodistribution with human epidermal growth factor receptor 3 targeting antibody ⁸⁹Zr-RG7116

scientific article

ImmunoPET with Anti-Mesothelin Antibody in Patients with Pancreatic and Ovarian Cancer before Anti-Mesothelin Antibody-Drug Conjugate Treatment.

scientific article

Immunoscintigraphy as potential tool in the clinical evaluation of HER2/neu targeted therapy

scientific article published on January 2008

In vivo VEGF imaging with radiolabeled bevacizumab in a human ovarian tumor xenograft.

scientific article

In vivo visualization of MET tumor expression and anticalin biodistribution with the MET-specific anticalin 89Zr-PRS-110 PET tracer.

scientific article published on 10 March 2014

Indium-111-labeled trastuzumab scintigraphy in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer.

scientific article published in May 2006

Lapatinib and 17AAG reduce 89Zr-trastuzumab-F(ab')2 uptake in SKBR3 tumor xenografts.

scientific article

Measurement of tumor VEGF-A levels with 89Zr-bevacizumab PET as an early biomarker for the antiangiogenic effect of everolimus treatment in an ovarian cancer xenograft model

scientific article

Molecular Imaging in Cancer Drug Development

scientific article published on 25 January 2018

Molecular Imaging of Radiolabeled Bispecific T-Cell Engager Zr-AMG211 Targeting CEA-Positive Tumors

scientific article published on 06 July 2018

Molecular imaging biomarkers for immune checkpoint inhibitor therapy

scientific article published on 01 January 2020

Molecular imaging of PD-L1 expression and dynamics with the adnectin-based PET tracer 18F-BMS-986192

scientific article published on 01 May 2020

Multidrug resistance in oncology and beyond: from imaging of drug efflux pumps to cellular drug targets

scientific article published in January 2010

PET with the 89Zr-labeled transforming growth factor-β antibody fresolimumab in tumor models

scientific article

Placental growth factor (PlGF)-specific uptake in tumor microenvironment of 89Zr-labeled PlGF antibody RO5323441.

scientific article published on 26 April 2013

Preclinical PET imaging of bispecific antibody ERY974 targeting CD3 and glypican 3 reveals that tumor uptake correlates to T cell infiltrate

scientific article published on 01 March 2020

Preclinical characterisation of 111In-DTPA-trastuzumab.

scientific article

Probody therapeutic design of 89Zr-CX-072 promotes accumulation in PD-L1 expressing tumors compared to normal murine lymphoid tissue

scientific article published on 17 January 2020

Rapid optical imaging of human breast tumour xenografts using anti-HER2 VHHs site-directly conjugated to IRDye 800CW for image-guided surgery

scientific article published on 19 June 2013

TGF-β Antibody Uptake in Recurrent High-Grade Glioma Imaged with 89Zr-Fresolimumab PET.

scientific article

Theranostics Using Antibodies and Antibody-Related Therapeutics.

scientific article published on September 2017

Threshold Analysis and Biodistribution of Fluorescently Labeled Bevacizumab in Human Breast Cancer

scientific article published on 22 November 2016

Transforming growth factor (TGF)-β expression and activation mechanisms as potential targets for anti-tumor therapy and tumor imaging.

scientific article published on 12 May 2012

Translation of New Molecular Imaging Approaches to the Clinical Setting: Bridging the Gap to Implementation.

scientific article published on February 2016

Trastuzumab pharmacokinetics influenced by extent human epidermal growth factor receptor 2-positive tumor load.

scientific article published on 10 May 2010

Tumor-Specific Uptake of Fluorescent Bevacizumab-IRDye800CW Microdosing in Patients with Primary Breast Cancer: A Phase I Feasibility Study

scientific article published on 9 November 2016

VEGF-PET imaging is a noninvasive biomarker showing differential changes in the tumor during sunitinib treatment

scientific article published on 17 November 2010

VEGF-SPECT with ¹¹¹In-bevacizumab in stage III/IV melanoma patients.

scientific article

Visualising dual downregulation of insulin-like growth factor receptor-1 and vascular endothelial growth factor-A by heat shock protein 90 inhibition effect in triple negative breast cancer.

scientific article

Zirconium-89-trastuzumab positron emission tomography as a tool to solve a clinical dilemma in a patient with breast cancer.

scientific article

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