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List of works by Margret Schottelius

"Luke! Luke! Don't! It's a trap!"-spotlight on bias in animal experiments in nuclear oncology

scientific article published on 10 February 2020

(18)F-Fluoroglucosylation of peptides, exemplified on cyclo(RGDfK).

scientific article

177Lu-Labeled Prostate-Specific Membrane Antigen Radioligand Therapy of Metastatic Castration-Resistant Prostate Cancer: Safety and Efficacy

scientific article

213Bi-Labeled Prostate-Specific Membrane Antigen-Targeting Agents Induce DNA Double-Strand Breaks in Prostate Cancer Xenografts

scientific article published on March 2017

68Ga- and 177Lu-Labeled PSMA I&T: Optimization of a PSMA-Targeted Theranostic Concept and First Proof-of-Concept Human Studies

scientific article

99mTechnetium-based Prostate-specific Membrane Antigen-radioguided Surgery in Recurrent Prostate Cancer

scientific article published on 3 April 2018

A conformationally frozen peptoid boosts CXCR4 affinity and anti-HIV activity

scientific article published on 3 July 2012

A new class of PentixaFor- and PentixaTher-based theranostic agents with enhanced CXCR4-targeting efficiency

scientific article published on 09 July 2020

Analyzing the Science Footprint of Richard P. Baum

At the bench: Pre-clinical evidence for multiple functions of CXCR4 in cancer

scientific article published on 26 October 2020

Biodistribution and radiation dosimetry for a probe targeting prostate-specific membrane antigen for imaging and therapy

scientific article published on 16 April 2015

Biodistribution and radiation dosimetry for the chemokine receptor CXCR4-targeting probe 68Ga-pentixafor

scientific article published on 19 February 2015

CXCR4 is a potential target for diagnostic PET/CT imaging in Barrett's dysplasia and esophageal adenocarcinoma.

scientific article published on 5 December 2017

CXCR4-directed endoradiotherapy induces high response rates in extramedullary relapsed Multiple Myeloma

scientific article

CXCR4-directed theranostics in oncology and inflammation

article published in 2018

Chemokine receptor - Directed imaging and therapy

scientific article published on 12 September 2017

Chemoselective hydrazone formation between HYNIC-functionalized peptides and 18F-fluorinated aldehydes

scientific article published on 01 February 2006

Chemoselective pre-conjugate radiohalogenation of unprotected mono- and multimeric peptides via oxime formation

Click Chemistry in the Design and Production of Hybrid Tracers

scientific article published on 22 July 2019

Comparison of radioiodinated TOC, TOCA and Mtr-TOCA: the effect of carbohydration on the pharmacokinetics

scientific article

Development of novel 68Ga- and 18F-labeled GnRH-I analogues with high GnRHR-targeting efficiency

scientific article

Disclosing the CXCR4 expression in lymphoproliferative diseases by targeted molecular imaging

scientific article

Dual Targeting of Acute Leukemia and Supporting Niche by CXCR4-Directed Theranostics.

scientific article published in January 2018

Effect of Carbohydration on the Theranostic Tracer PSMA I&T

scientific article published on 25 July 2018

Entering the era of molecular-targeted precision surgery in recurrent prostate cancer

scientific article published on 20 December 2018

First (18)F-labeled tracer suitable for routine clinical imaging of sst receptor-expressing tumors using positron emission tomography

scientific article published on June 2004

First 18F-Labeled Pentixafor-Based Imaging Agent for PET Imaging of CXCR4 Expression In Vivo

scientific article published on 01 June 2016

First-in-Human Experience of CXCR4-Directed Endoradiotherapy with 177Lu- and 90Y-Labeled Pentixather in Advanced-Stage Multiple Myeloma with Extensive Intra- and Extramedullary Disease.

scientific article published on 12 November 2015

From Theranostics to Immunotheranostics: the Concept

scientific article published on 08 April 2020

Fusion of a recombinant antibody fragment with a homo-amino-acid polymer: effects on biophysical properties and prolonged plasma half-life

scientific article published on 26 June 2007

Gluc-Lys([18F]FP)-TOCA PET in patients with SSTR-positive tumors: biodistribution and diagnostic evaluation compared with [111In]DTPA-octreotide.

scientific article

Hybrid Tracers Based on Cyanine Backbones Targeting Prostate-Specific Membrane Antigen: Tuning Pharmacokinetic Properties and Exploring Dye-Protein Interaction

scientific article published on 03 September 2019

Image-Guided Surgery: Are We Getting the Most Out of Small-Molecule Prostate-Specific-Membrane-Antigen-Targeted Tracers?

scientific article published on 06 January 2020

Imaging the Cytokine Receptor CXCR4 in Atherosclerotic Plaques with the Radiotracer 68Ga-Pentixafor for PET.

scientific article published on 27 October 2016

Improvement of pharmacokinetics of radioiodinated Tyr(3)-octreotide by conjugation with carbohydrates

scientific article published in September 2002

In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma

scientific article

Intrapatient Comparison of 111In-PSMA I&T SPECT/CT and Hybrid 68Ga-HBED-CC PSMA PET in Patients With Early Recurrent Prostate Cancer.

scientific article published on 6 June 2016

Ligands for mapping alphavbeta3-integrin expression in vivo.

scientific article published in July 2009

Modulation of pharmacokinetics of radioiodinated sugar-conjugated somatostatin analogues by variation of peptide net charge and carbohydration chemistry

scientific article

Molecular imaging targeting peptide receptors

scientific article published on 24 March 2009

N-terminal sugar conjugation and C-terminal Thr-for-Thr(ol) exchange in radioiodinated Tyr3-octreotide: effect on cellular ligand trafficking in vitro and tumor accumulation in vivo

scientific article

New Developments in Peptide Receptor Radionuclide Therapy

scientific article published on 20 December 2018

Novel Peptide-Based PET Probe for Non-invasive Imaging of C-X-C Chemokine Receptor Type 4 (CXCR4) in Tumors

scientific article published in 2021

Orthogonally protected artificial amino acid as tripod ligand for automated peptide synthesis and labeling with [(99m)Tc(OH(2))(3)(CO)(3)](+).

scientific article published on 26 December 2012

PET of CXCR4 expression by a (68)Ga-labeled highly specific targeted contrast agent

scientific article published in November 2011

PSMA Theranostics Using PET and Subsequent Radioguided Surgery in Recurrent Prostate Cancer

scientific article published on 27 May 2016

PSMA-Targeted Radiopharmaceuticals for Imaging and Therapy

scientific article published on 30 April 2019

Peptide-Receptor Radiotherapy with CXCR4-Targeting Pentixather Reduces Leukemia Burden in Acute Leukemia PDX and Patients ⬇️

scholarly article

Perspectives on translational molecular imaging and therapy: an overview of key questions to be addressed

scientific article published on 02 June 2022

Pharmacophoric modifications lead to superpotent αvβ3 integrin ligands with suppressed α5β1 activity

scientific article

Preclinical Evaluation and First Patient Application of 99mTc-PSMA-I&S for SPECT Imaging and Radioguided Surgery in Prostate Cancer

scientific article

Preclinical evaluation of [(68)Ga]NOTA-pentixafor for PET imaging of CXCR4 expression in vivo - a comparison to [(68)Ga]pentixafor.

scientific article published on 21 September 2016

Prostate-specific membrane antigen-radioguided surgery for metastatic lymph nodes in prostate cancer

scientific article published on 6 May 2015

Radiolabeled carbohydrated somatostatin analogs: a review of the current status

scientific article published on April 2004

Rapid and high-yield solution-phase synthesis of DOTA-Tyr3-octreotide and DOTA-Tyr3-octreotate using unprotected DOTA

Single Lesion on Prostate-specific Membrane Antigen-ligand Positron Emission Tomography and Low Prostate-specific Antigen Are Prognostic Factors for a Favorable Biochemical Response to Prostate-specific Membrane Antigen-targeted Radioguided Surgery

scientific article published on 12 April 2019

Synthesis and Preclinical Characterization of the PSMA-Targeted Hybrid Tracer PSMA-I&F for Nuclear and Fluorescence Imaging of Prostate Cancer

Synthesis and in vitro and in vivo evaluation of urea-based PSMA inhibitors with increased lipophilicity

scientific article published on 22 August 2018

Synthesis and preclinical evaluation of DOTAGA-conjugated PSMA ligands for functional imaging and endoradiotherapy of prostate cancer

scientific article published on 25 November 2014

Synthesis and preclinical evaluation of novel 18F-labeled Glu-urea-Glu-based PSMA inhibitors for prostate cancer imaging: a comparison with 18F-DCFPyl and 18F-PSMA-1007.

scientific article published on 12 April 2018

Synthesis of novel 1,4,7,10-tetraazacyclodecane-1,4,7,10-tetraacetic acid (DOTA) derivatives for chemoselective attachment to unprotected polyfunctionalized compounds

scientific article

Systemic Radioligand Therapy with (177)Lu Labeled Prostate Specific Membrane Antigen Ligand for Imaging and Therapy in Patients with Metastatic Castration Resistant Prostate Cancer

scientific article published on 7 March 2016

Targeted positron emission tomography imaging of CXCR4 expression in patients with acute myeloid leukemia

scientific article published on 12 May 2016

The influence of different metal-chelate conjugates of pentixafor on the CXCR4 affinity

scientific article published on 26 April 2016

Towards Personalized Treatment of Prostate Cancer: PSMA I&T, a Promising Prostate-Specific Membrane Antigen-Targeted Theranostic Agent

scientific article published on 12 April 2016

Trending: Radioactive and Fluorescent Bimodal/Hybrid Tracers as Multiplexing Solutions for Surgical Guidance

scientific article published on 11 November 2019

Twins in spirit - episode I: comparative preclinical evaluation of [(68)Ga]DOTATATE and [(68)Ga]HA-DOTATATE

scientific article

Twins in spirit part II: DOTATATE and high-affinity DOTATATE--the clinical experience

scientific article published on 15 February 2014

Twins in spirit part IV - [177Lu] high affinity DOTATATE. A promising new tracer for peptide receptor radiotherapy?

scientific article published on 31 January 2017

Twins in spirit: DOTATATE and high-affinity DOTATATE.

scientific article published on 21 August 2013

Two-step methodology for high-yield routine radiohalogenation of peptides: (18)F-labeled RGD and octreotide analogs

scientific article

Validation of [125I]CPCR4.3 as an investigative tool for the sensitive and specific detection of hCXCR4 and mCXCR4 expression in vitro and in vivo

scientific article published on 13 August 2019

Value of 111 In-prostate-specific membrane antigen (PSMA)-radioguided surgery for salvage lymphadenectomy in recurrent prostate cancer: correlation with histopathology and clinical follow-up.

scientific article published on 10 November 2016

[(111)In]PSMA-I&T: expanding the spectrum of PSMA-I&T applications towards SPECT and radioguided surgery

scientific article

[123I]Mtr-TOCA, a radioiodinated and carbohydrated analogue of octreotide: scintigraphic comparison with [111In]octreotide

scientific article

[177Lu]pentixather: Comprehensive Preclinical Characterization of a First CXCR4-directed Endoradiotherapeutic Agent.

scientific article published on 11 June 2017

[99cmTc]Tc-PSMA-I&S-SPECT/CT: experience in prostate cancer imaging in an outpatient center

scientific article published on 07 May 2020

[Cu]NOTA-pentixather enables high resolution PET imaging of CXCR4 expression in a preclinical lymphoma model

scientific article published on 19 January 2017

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