Search filters

List of works by Robert Tjian

3D ATAC-PALM: super-resolution imaging of the accessible genome

scientific article published on 16 March 2020

3D imaging of Sox2 enhancer clusters in embryonic stem cells

scientific article

A DNA repair complex functions as an Oct4/Sox2 coactivator in embryonic stem cells

scientific article

A dynamic interplay of enhancer elements regulates Klf4 expression in naïve pluripotency

scientific article published in September 2017

A dynamic mode of mitotic bookmarking by transcription factors

scientific article published on 18 November 2016

A new focus on plant sciences ⬇️

scientific article published on November 19, 2010

A specific E3 ligase/deubiquitinase pair modulates TBP protein levels during muscle differentiation

scientific article

A stable mode of bookmarking by TBP recruits RNA polymerase II to mitotic chromosomes

scientific article published on 25 June 2018

An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis

scientific article

Architectural Features of 3D Genome Organization Revealed by Counting CTCF and Cohesin Molecules

scholarly article published 17 July 2018

Architecture of the human XPC DNA repair and stem cell coactivator complex

scientific article

BRD2 compartmentalizes the accessible genome

scientific article published on 11 April 2022

Bromodomains mediate an acetyl-histone encoded antisilencing function at heterochromatin boundaries

scientific article

CASFISH: CRISPR/Cas9-mediated in situ labeling of genomic loci in fixed cells

scientific article

CTCF and cohesin regulate chromatin loop stability with distinct dynamics

scientific article

Cell-type-selective induction of c-jun by TAF4b directs ovarian-specific transcription networks

scientific article

Charting Brachyury-mediated developmental pathways during early mouse embryogenesis

scientific article

Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation

scientific article

Climate change and the integrity of science

scientific article

Coactivator cross-talk specifies transcriptional output

scientific article published on June 2006

Codependent activators direct myoblast-specific MyoD transcription

scientific article published on October 2008

Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway

scientific article

Control of embryonic stem cell lineage commitment by core promoter factor, TAF3.

scientific article

Core promoter factor TAF9B regulates neuronal gene expression

scientific article

Core promoter recognition complex changes accompany liver development ⬇️

scientific article published on February 22, 2011

Cryo-electron microscopy studies of human TFIID: conformational breathing in the integration of gene regulatory cues

scientific article

Daniel E. Koshland, Jr. (1920-2007).

scientific article

Daniel E. Koshland, Jr. 1902-2007.

scientific article

Determining cellular CTCF and cohesin abundances to constrain 3D genome models

scientific article published on 17 June 2019

Distinct conformational states of nuclear receptor-bound CRSP-Med complexes

scientific article

Diversified transcription initiation complexes expand promoter selectivity and tissue-specific gene expression

scientific article (publication date: June 2003)

Dual functions of TAF7L in adipocyte differentiation

scientific article published on 8 January 2013

Dynamics of CRISPR-Cas9 genome interrogation in living cells

scientific article published on November 2015

ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a

scientific journal article

Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation

scientific article published on 07 May 2019

Evidence for an Integrated Gene Repression Mechanism Based on mRNA Isoform Toggling in Human Cells

article

Evidence for an Integrated Gene Repression Mechanism based on mRNA Isoform Toggling in Human Cells

article

Functional and mechanistic studies of XPC DNA-repair complex as transcriptional coactivator in embryonic stem cells

scientific article published on 21 April 2015

Gene-specific transcriptional mechanisms at the histone gene cluster revealed by single-cell imaging

scientific article

Genomes in Focus: Development and Applications of CRISPR-Cas9 Imaging Technologies.

scientific article

Guided nuclear exploration increases CTCF target search efficiency

scientific article published on 02 December 2019

Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation

scientific article

IRES-mediated functional coupling of transcription and translation amplifies insulin receptor feedback

scientific article (publication date: 15 January 2007)

Imaging Transcription: Past, Present, and Future

scientific article

Imaging dynamic and selective low-complexity domain interactions that control gene transcription

scientific article published in Science

In vitro analysis of huntingtin-mediated transcriptional repression reveals multiple transcription factor targets

scientific article published on December 2005

Looping back to leap forward: transcription enters a new era

scientific article

MEF2C and EBF1 Co-regulate B Cell-Specific Transcription

scientific article published on 22 February 2016

Maintenance of spermatogenesis requires TAF4b, a gonad-specific subunit of TFIID.

scientific article

MeCP2 nuclear dynamics in live neurons results from low and high affinity chromatin interactions

scientific article published on 23 December 2019

Measuring dynamics of eukaryotic transcription initiation: Challenges, insights and opportunities

scientific article published on 18 September 2017

Myc-interacting protein 1 target gene profile: a link to microtubules, extracellular signal-regulated kinase, and cell growth

scholarly article

MyoD targets TAF3/TRF3 to activate myogenin transcription.

scientific article

Near-atomic resolution visualization of human transcription promoter opening

scientific article

Neurodegeneration. A glutamine-rich trail leads to transcription factors

scientific article

Not just Salk

scientific article published in September 2017

Novel TRF1/BRF target genes revealed by genome-wide analysis of Drosophila Pol III transcription

scientific article published on 14 December 2006

Nucleosomes impede Cas9 access to DNA in vivo and in vitro

scientific article published on 17 March 2016

Nutrient availability and growth: regulation of insulin signaling by dFOXO/FOXO1.

scientific article

Open-source RNA extraction and RT-qPCR methods for SARS-CoV-2 detection

scientific article published in 2021

Polybromo protein BAF180 functions in mammalian cardiac chamber maturation

scientific journal article

Promoter-specific activation of RNA polymerase II transcription by Sp1

scientific article published in January 1986

Rapid dynamics of general transcription factor TFIIB binding during preinitiation complex assembly revealed by single-molecule analysis

scientific article

Real-time imaging of Huntingtin aggregates diverting target search and gene transcription

scientific article published on 3 August 2016

Recent evidence that TADs and chromatin loops are dynamic structures

scientific article

Redundant role of tissue-selective TAF(II)105 in B lymphocytes

scientific article

Regulating the regulators: lysine modifications make their mark

scientific article

Regulation of DNA demethylation by the XPC DNA repair complex in somatic and pluripotent stem cells

scientific article published on April 2017

Regulation of Viral Transcription and DNA Replication by the SV40 Large T Antigen ⬇️

scientific article published on January 1, 1981

Regulatory diversity among metazoan co-activator complexes

scientific article published on May 2004

Robust model-based analysis of single-particle tracking experiments with Spot-On.

scientific article published on 4 January 2018

Shifting players and paradigms in cell-specific transcription

scientific article published on December 2009

Single-molecule dynamics of enhanceosome assembly in embryonic stem cells

scientific article

Single-molecule tracking of the transcription cycle by sub-second RNA detection

scientific article published on 28 January 2014

Spot-On: robust model-based analysis of single-particle tracking experiments

Structural changes in TAF4b-TFIID correlate with promoter selectivity

scientific article

Structural studies of the human PBAF chromatin-remodeling complex

scientific article

Structure and function of CRSP/Med2; a promoter-selective transcriptional coactivator complex

scientific article published in June 2004

Structure of the human SAGA coactivator complex

scientific article published on 22 November 2021

Structure, function, and activator-induced conformations of the CRSP coactivator

scientific article

Structures of three distinct activator-TFIID complexes

scientific article published on July 2009

Sub-nuclear compartmentalization of core promoter factors and target genes ⬇️

scientific article published on August 1, 2011

Subnuclear segregation of genes and core promoter factors in myogenesis

scientific article published on 28 February 2011

Switching of the core transcription machinery during myogenesis

scientific journal article

TAF4 nucleates a core subcomplex of TFIID and mediates activated transcription from a TATA-less promoter

scholarly article

TAF7L modulates brown adipose tissue formation

scientific article

TBP, Mot1, and NC2 establish a regulatory circuit that controls DPE-dependent versus TATA-dependent transcription

scientific article published on 14 August 2008

TRF2 associates with DREF and directs promoter-selective gene expression in Drosophila

scientific article

Taf7l cooperates with Trf2 to regulate spermiogenesis

scientific article published on 30 September 2013

Targeting genes and transcription factors to segregated nuclear compartments

scientific article

The dyskerin ribonucleoprotein complex as an OCT4/SOX2 coactivator in embryonic stem cells

scientific article

The future for Howard Hughes. Interview by Erika Check Hayden

scientific article published in October 2008

The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans

scientific article

The intertwined roles of transcription and repair proteins

scientific article

The nucleosome remodeling factor (NURF) regulates genes involved in Drosophila innate immunity.

scientific article

Transcription initiation by human RNA polymerase II visualized at single-molecule resolution

scientific article

Transcription of histone gene cluster by differential core-promoter factors

scientific article

Transcriptional feedback control of insulin receptor by dFOXO/FOXO1.

scientific article

Transcriptional regulation by coactivators in embryonic stem cells

scientific article

Transient DNA Binding Induces RNA Polymerase II Compartmentalization During Herpesviral Infection Distinct From Phase Separation

Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection

scientific article published on 26 September 2016

Unexpected roles for core promoter recognition factors in cell-type-specific transcription and gene regulation

scientific article

Visualizing transcription factor dynamics in living cells.

scientific article

Wnt signaling targets ETO coactivation domain of TAF4/TFIID in vivo

scholarly article

dCas9-targeted locus-specific protein isolation method identifies histone gene regulators

scientific article published on 5 March 2018

Paulina is supported by:

About Paulina

Help