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List of works by Erik Laurini

2-Difluoromethylene-4-methylenepentanoic Acid, A Paradoxical Probe Able To Mimic the Signaling Role of 2-Oxoglutaric Acid in Cyanobacteria

scientific article published on 05 May 2011

3-Aryl-2-[1H-benzotriazol-1-yl]acrylonitriles: a novel class of potent tubulin inhibitors

scientific article published on 8 July 2011

3D Homology Model of Sigma1 Receptor

scientific article published in July 2017

A 3D-pharmacophore model for sigma2 receptors based on a series of substituted benzo[d]oxazol-2(3H)-one derivatives

scientific article published on 4 March 2010

A dual targeting dendrimer-mediated siRNA delivery system for effective gene silencing in cancer therapy

article

A self-assembling amphiphilic dendrimer nanotracer for SPECT imaging

scientific article published on 01 December 2019

Another brick in the wall. Validation of the σ1 receptor 3D model by computer-assisted design, synthesis, and activity of new σ1 ligands

scientific article published on 12 October 2012

Antimycobacterial activity of new 3,5-disubstituted 1,3,4-oxadiazol-2(3H)-one derivatives. Molecular modeling investigations.

scientific article published on 3 May 2009

Are two better than one? A novel double-mutant KIT in GIST that responds to Imatinib

scientific article published on 21 March 2013

Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds: promising neuroprotective agents acting as σ₁ receptor agonists

scientific article published on 5 July 2013

Copper(ii) binding to flexible triethanolamine-core PAMAM dendrimers: a combined experimental/in silico approach

scientific article published on 01 January 2014

Direct Identification of α-Bisabolol Enantiomers in an Essential Oil Using a Combined Ion Mobility-Mass Spectrometry/Quantum Chemistry Approach

scientific article published on 26 March 2020

Evolution from Covalent to Self-Assembled PAMAM-Based Dendrimers as Nanovectors for siRNA Delivery in Cancer by Coupled In Silico-Experimental Studies. Part I: Covalent siRNA Nanocarriers

scientific article published on 18 July 2019

Evolution from Covalent to Self-Assembled PAMAM-Based Dendrimers as Nanovectors for siRNA Delivery in Cancer by Coupled in Silico-Experimental Studies. Part II: Self-Assembled siRNA Nanocarriers

scientific article published on 10 July 2019

Hitting the right spot: Mechanism of action of OPB-31121, a novel and potent inhibitor of the Signal Transducer and Activator of Transcription 3 (STAT3)

scientific article

Homology Model and Docking-Based Virtual Screening for Ligands of the σ1 Receptor.

scientific article published on 27 August 2011

Identification of RC-33 as a potent and selective σ1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-Scale synthesis, physicochemical characterization and in vitro metabolic stability

scientific article published on 26 February 2013

Identification, pharmacological evaluation and binding mode analysis of novel chromene and chromane based σ1 receptor ligands

scientific article published on 26 June 2014

Imatinib response in two GIST patients carrying two hitherto functionally uncharacterized PDGFRA mutations: an imaging, biochemical and molecular modeling study

scientific article published in February 2011

Impact of siRNA overhangs for dendrimer-mediated siRNA delivery and gene silencing.

scientific article published on 25 July 2013

Improving selectivity preserving affinity: New piperidine-4-carboxamide derivatives as effective sigma-1-ligands

scientific article published on 12 December 2014

In vitro and in silico studies of MDM2/MDMX isoforms predict Nutlin-3A sensitivity in well/de-differentiated liposarcomas.

scientific article published on 9 September 2013

Mimicking the 2-oxoglutaric acid signalling function using molecular probes: insights from structural and functional investigations

scientific article published on 01 July 2014

Mitochondrial dysfunction induced by a SH2 domain-targeting STAT3 inhibitor leads to metabolic synthetic lethality in cancer cells

scientific article published on 5 June 2017

Mix and Match: Coassembly of Amphiphilic Dendrimers and Phospholipids Creates Robust, Modular, and Controllable Interfaces

scientific article

Molecular dynamics reveal BCR-ABL1 polymutants as a unique mechanism of resistance to PAN-BCR-ABL1 kinase inhibitor therapy.

scientific article published on 18 February 2014

Nanomechanical DNA resonators for sensing and structural analysis of DNA-ligand complexes

scientific article published on 12 April 2019

New flavonoid – N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer´s disease endowed with neurogenic properties

scientific article published on 01 December 2019

Perceptions and Misconceptions in Molecular Recognition: Key Factors in Self-Assembling Multivalent (SAMul) Ligands/Polyanions Selectivity

scientific article published on 24 February 2020

Quinolizidine-Derived Lucanthone and Amitriptyline Analogues Endowed with Potent Antileishmanial Activity

scientific article published on 25 October 2020

Rationalizing the F⋯S interaction discovered within a tetrafluorophenylazido-containing bola-phospholipid

scientific article published on 08 February 2012

Self-Assembled Nanomicelles as Curcumin Drug Delivery Vehicles: Impact on Solitary Fibrous Tumor Cell Protein Expression and Viability

scientific article published on 17 September 2018

Self-assembled multivalent (SAMul) ligand systems with enhanced stability in the presence of human serum

scientific article published on 01 August 2019

Self-assembling supramolecular dendrimer nanosystem for PET imaging of tumors

article published in the Proceedings of the National Academy of Sciences of the United States of America

Smoothened (SMO) receptor mutations dictate resistance to vismodegib in basal cell carcinoma.

scientific article published on 26 September 2014

Structural Requirements of 2-Oxoglutaric Acid Analogues To Mimic Its Signaling Function

scientific article published on 29 August 2013

Synergistic experimental/computational studies on arylazoenamine derivatives that target the bovine viral diarrhea virus RNA-dependent RNA polymerase.

scientific article published on 25 June 2010

Synthesis and Structure-Affinity Relationships of Spirocyclic Benzopyrans with Exocyclic Amino Moiety

scientific article published on 12 April 2019

Synthesis and receptor binding studies of some new arylcarboxamide derivatives as sigma-1 ligands

scientific article

Synthesis, biological evaluation, and three-dimensional in silico pharmacophore model for sigma(1) receptor ligands based on a series of substituted benzo[d]oxazol-2(3H)-one derivatives

scientific article published in September 2009

Through the open door: Preferential binding of dasatinib to the active form of BCR-ABL unveiled by in silico experiments

scientific article published on 15 June 2013

Unchain My Blood: Lessons Learned from Self-Assembled Dendrimers as Nanoscale Heparin Binders

scientific article published on 20 August 2019

β-Catenin in desmoid-type fibromatosis: deep insights into the role of T41A and S45F mutations on protein structure and gene expression.

scientific article published on 19 June 2017

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