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List of works by Chi-Huey Wong

2G12-expressing B cell lines may aid in HIV carbohydrate vaccine design strategies

scientific article published on 5 December 2012

4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting the colchicine site of β-tubulin

scientific article published on 02 August 2019

6,8-Di-C-glycosyl flavonoids from Dendrobium huoshanense

scientific article published in February 2010

6-Alkynyl fucose is a bioorthogonal analog for O-fucosylation of epidermal growth factor-like repeats and thrombospondin Type-1 repeats by protein O-fucosyltransferases 1 and 2 ⬇️

scientific article published on October 8, 2012

A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2

scientific article published on 24 July 2020

A General Strategy toward S-Linked Glycopeptides

scientific article published on 01 July 2005

A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope.

scientific article published on 7 March 2018

A New Route to Deoxythio sugars Based on Aldolases

scientific article published in 1994

A New Synthetic Approach toward Bacterial Transglycosylase Substrates, Lipid II and Lipid IV ⬇️

scientific article published on July 28, 2011

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

scientific article

A Practical Synthesis of Zanamivir Phosphonate Congeners with Potent Anti-influenza Activity ⬇️

scientific article published on October 14, 2011

A Programmable One‐Pot Oligosaccharide Synthesis for Diversifying the Sugar Domains of Natural Products: A Case Study of Vancomycin ⬇️

scientific article published on October 6, 2003

A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans.

scientific article published on July 2016

A Weak Calcium Binding Site in Subtilisin BPN‘ Has a Dramatic Effect on Protein Stability

scientific article published in January 1996

A cell-permeable and triazole-forming fluorescent probe for glycoconjugate imaging in live cells.

scientific article published on 13 January 2017

A common glycan structure on immunoglobulin G for enhancement of effector functions

scientific article

A concise and flexible synthesis of the potent anti-influenza agents tamiflu and tamiphosphor.

scientific article published in January 2008

A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses

scientific article

A copper(I)-catalyzed 1,2,3-triazole azide-alkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variant

scientific article published on 30 September 2008

A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120

scientific article published on 23 April 2008

A glycolipid adjuvant, 7DW8-5, enhances CD8+ T cell responses induced by an adenovirus-vectored malaria vaccine in non-human primates

scientific article

A new reactivity-based one-pot synthesis of N-acetyllactosamine oligomers.

scientific article published in March 2003

A new strategy for glycoprotein synthesis: ligation of synthetic glycopeptides with truncated proteins expressed in E. coli as TEV protease cleavable fusion protein

scientific article

A pH sensitive colorometric assay for the high-throughput screening of enzyme inhibitors and substrates: a case study using kinases

scientific article published in March 2002

A quick diversity-oriented amide-forming reaction to optimize P-subsite residues of HIV protease inhibitors

scientific article

Acceptor specificity and inhibition of the bacterial cell-wall glycosyltransferase MurG.

scientific article

Acyl and Silyl Group Effects in Reactivity-Based One-Pot Glycosylation: Synthesis of Embryonic Stem Cell Surface Carbohydrates Lc4 and IV2Fuc-Lc4 ⬇️

scientific article published on 05 March 2012

Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins

scientific article published on 30 October 2009

Advances in glycoprotein synthesis

scientific article published on 23 November 2005

Affinity-Based Screen for Inhibitors of Bacterial Transglycosylase

scientific article published on 7 February 2018

Alkali-soluble polysaccharides of Rhizoclonium riparium alga induce IL-1 gene expression via protein kinase signaling pathways

scientific article published on May 2006

Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells.

scholarly article

Altered gag polyprotein cleavage specificity of feline immunodeficiency virus/human immunodeficiency virus mutant proteases as demonstrated in a cell-based expression system

scientific article

An Effective Bacterial Fucosidase for Glycoprotein Remodeling

scientific article

An Efficient Modular One-Pot Synthesis of Heparin-Based Anticoagulant Idraparinux

scientific article published on 19 June 2019

An azido-BODIPY probe for glycosylation: initiation of strong fluorescence upon triazole formation.

scientific article

Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses

scientific article published on 8 April 2010

Analysis of the class I aldolase binding site architecture based on the crystal structure of 2-deoxyribose-5-phosphate aldolase at 0.99A resolution

scientific article

Anti-carbohydrate antibodies elicited by polyvalent display on a viral scaffold

scientific article published on 01 August 2007

Antibody recognition of a carbohydrate epitope: a template for HIV vaccine design.

scientific article

Autoreactivity to Sulfatide by Human Invariant NKT Cells

scientific article published on 19 May 2017

Avidity of CD1d-ligand-receptor ternary complex contributes to T-helper 1 (Th1) polarization and anticancer efficacy

scientific article

B-cell maturation antigen is modified by a single N-glycan chain that modulates ligand binding and surface retention

scientific article published on 17 June 2013

Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells

scientific article

Borate as a Phosphate Ester Mimic in Aldolase-Catalyzed Reactions: Practical Synthesis ofL-Fructose andL-Iminocyclitols

article

Broad neutralization coverage of HIV by multiple highly potent antibodies

scientific article (publication date: 22 September 2011)

Broadly neutralizing DNA vaccine with specific mutation alters the antigenicity and sugar-binding activities of influenza hemagglutinin ⬇️

scientific article published on February 14, 2011

Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers

scientific article published on 24 April 2014

CLEC4F is an inducible C-type lectin in F4/80-positive cells and is involved in alpha-galactosylceramide presentation in liver

scientific journal article

Carbohydrate microarray for profiling the antibodies interacting with Globo H tumor antigen

scholarly article

Carbohydrate microarrays - a new set of technologies at the frontiers of glycomics

scientific article published on October 2003

Carbohydrate-based vaccines with a glycolipid adjuvant for breast cancer

scientific article

Cell-permeable probe for identification and imaging of sialidases

scientific article published on 28 January 2013

Cell-wall engineering of living bacteria

scientific article published in August 2002

Characterization of a transglycosylase domain of Streptococcus pneumoniae PBP1b

scientific article published on 25 July 2006

Characterization of the sialic acid binding activity of influenza A viruses using soluble variants of the H7 and H9 hemagglutinins

scientific article

Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease

scientific article

Chemical constituents of Plectranthus amboinicus and the synthetic analogs possessing anti-inflammatory activity

scientific article published on 12 January 2014

Chemical probes for drug-resistance assessment by binding competition (RABC): oseltamivir susceptibility evaluation

scientific article published on 13 November 2012

Chemistry and glycobiology ⬇️

scientific article published on April 18, 2011

Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling

scientific article published on 5 February 2018

Chemoenzymatic synthesis of oligosaccharides and glycoproteins

scientific article

Chimeric hemagglutinin vaccine elicits broadly protective CD4 and CD8 T cell responses against multiple influenza strains and subtypes

scientific article published on 15 July 2020

Colocalization of a CD1d-Binding Glycolipid with a Radiation-Attenuated Sporozoite Vaccine in Lymph Node-Resident Dendritic Cells for a Robust Adjuvant Effect

scientific article

Concise synthesis of iminocyclitols via Petasis-type aminocyclization

scientific article

Conjugation of glycopeptide thioesters to expressed protein fragments: semisynthesis of glycosylated interleukin-2.

scientific article

Conserved and Heterogeneous Lipid Antigen Specificities of CD1d-Restricted NKT Cell Receptors

scientific article published on 01 March 2006

Convergent glycopeptide synthesis by traceless Staudinger ligation and enzymatic coupling

scientific article published in March 2006

Correction: Development of glycosynthases with broad glycan specificity for the efficient glyco-remodeling of antibodies

scientific article published on 01 July 2018

Corrigendum

scholarly article published in Journal of the Chemical Society. Perkin transactions 1

Covalent display of oligosaccharide arrays in microtiter plates

scientific article published in July 2004

Crystal Structure of a Homogeneous IgG-Fc Glycoform with the N-Glycan Designed to Maximize the Antibody Dependent Cellular Cytotoxicity.

scientific article

Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism

scientific article

Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli

scientific article

Cysteine-free peptide and glycopeptide ligation by direct aminolysis

scientific article published in January 2008

D-Fructose-6-phosphate aldolase-catalyzed one-pot synthesis of iminocyclitols.

scientific article published on 7 November 2007

Defining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds

scientific article

Dengue Virus Infection Is through a Cooperative Interaction between a Mannose Receptor and CLEC5A on Macrophage as a Multivalent Hetero-Complex.

scientific article

Design and synthesis of glyco-peptides as anti-cancer agents targeting thrombin-protease activated receptor-1 interaction

scientific article published on 24 April 2020

Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant

scientific article

Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d

scholarly article

Design, synthesis, and evaluation of trifluoromethyl ketones as inhibitors of SARS-CoV 3CL protease

scientific article published on 15 February 2008

Desorption ionization of biomolecules on metals

scientific article

Development of a universal influenza vaccine using hemagglutinin stem protein produced from Pichia pastoris

article

Development of glycosynthases with broad glycan specificity for the efficient glyco-remodeling of antibodies

scientific article published on 01 June 2018

Development of oseltamivir phosphonate congeners as anti-influenza agents

scientific article

Development of trifunctional probes for glycoproteomic analysis

scientific article

Different immunity elicited by recombinant H5N1 hemagglutinin proteins containing pauci-mannose, high-mannose, or complex type N-glycans

scientific article

Differential Receptor Binding Affinities of Influenza Hemagglutinins on Glycan Arrays ⬇️

scientific article published on October 27, 2010

Directed evolution of D-sialic acid aldolase to L-3-deoxy-manno-2-octulosonic acid (L-KDO) aldolase

scientific article

Directed evolution of N-acetylneuraminic acid aldolase to catalyze enantiomeric aldol reactions

scientific article

Directed evolution of aldolases

scientific article published in January 2004

Discovery of picomolar slow tight-binding inhibitors of alpha-fucosidase

scientific article published in September 2004

Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease

scientific article published in June 2005

Disrupting the Conserved Salt Bridge in the Trimerization of Influenza A Nucleoprotein

scientific article published on 17 December 2019

Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.

scientific article

Dual effect of synthetic aminoglycosides: antibacterial activity against Bacillus anthracis and inhibition of anthrax lethal factor

scientific article published in January 2005

E339...R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors

scientific article

Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch

scientific article published on May 2016

Effect of Reishi polysaccharides on human stem/progenitor cells

scientific article published on 04 November 2010

Effect of the Peptide Moiety of Lipid II on Bacterial Transglycosylase ⬇️

scientific article published on September 5, 2012

Effective sugar nucleotide regeneration for the large-scale enzymatic synthesis of Globo H and SSEA4

scientific article published on 17 September 2013

Effects of neighboring glycans on antibody-carbohydrate interaction

scientific article

Efficient and Stereoselective Synthesis of α(2→9) Oligosialic Acids: From Monomers to Dodecamers ⬇️

scientific article published on August 29, 2011

Efficient convergent synthesis of bi-, tri-, and tetra-antennary complex type N-glycans and their HIV-1 antigenicity

scientific article

Egg-based influenza split virus vaccine with monoglycosylation induces cross-strain protection against influenza virus infections

scientific article published on 19 February 2019

Engineering transaldolase in Pichia stipitis to improve bioethanol production

article

Enhanced anti-influenza agents conjugated with anti-inflammatory activity.

scientific article published on 20 September 2012

Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.

scientific article

Enzymatic synthesis of lipid II and analogues.

scientific article

Enzymes in organic synthesis: oxidoreductions

article

Enzymes in organic synthesis: synthesis of highly enantiomerically pure 1,2-epoxy aldehydes, epoxy alcohols, thiirane, aziridine, and glyceraldehyde 3-phosphate

scientific article published in August 1990

Epoxide opening in water and screening in situ for rapid discovery of enzyme inhibitors in microtiter plates

scientific article published on 4 November 2005

Evaluation of RNA-binding specificity of aminoglycosides with DNA microarrays

scholarly article

Evaluation of sulfatase-directed quinone methide traps for proteomics ⬇️

scientific article published on April 24, 2011

Expression of Globo H and SSEA3 in breast cancer stem cells and the involvement of fucosyl transferases 1 and 2 in Globo H synthesis

scholarly article

Extended sugar-assisted glycopeptide ligations: development, scope, and applications

scientific article published on 13 October 2007

Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways

scientific article

Extract of Reishi polysaccharides induces cytokine expression via TLR4-modulated protein kinase signaling pathways

scientific article

Fabrication of an Oriented Fc-Fused Lectin Microarray through Boronate Formation

scientific article published on 01 January 2008

Fabrication of an Oriented Fc-Fused Lectin Microarray through Boronate Formation

article

Facile synthesis of metal-chelating peptides on chip for protein array

scientific article published in April 2004

Free-electron-laser coherent diffraction images of individual drug-carrying liposome particles in solution

scientific article published on 24 January 2018

Fucosyltransferase 8 as a functional regulator of nonsmall cell lung cancer ⬇️

scientific article published on December 24, 2012

Galectin-3 Binding Protein and Galectin-1 Interaction in Breast Cancer Cell Aggregation and Metastasis

scientific article published on 22 July 2015

Ganoderma lucidum Polysaccharides Induce Macrophage-Like Differentiation in Human Leukemia THP-1 Cells via Caspase and p53 Activation

scientific article

Ganoderma lucidum polysaccharides enhance CD14 endocytosis of LPS and promote TLR4 signal transduction of cytokine expression

scientific article published on 01 August 2007

Ganoderma lucidum polysaccharides in human monocytic leukemia cells: from gene expression to network construction ⬇️

scientific article

Gaucher disease-associated glucocerebrosidases show mutation-dependent chemical chaperoning profiles

scientific article published in November 2005

Glucosamine‐6‐sulfamate Analogues of Heparan Sulfate as Inhibitors of Endosulfatases ⬇️

scientific article published on November 22, 2010

Glycan Array on Aluminum Oxide-Coated Glass Slides through Phosphonate Chemistry ⬇️

scientific article published on September 29, 2010

Glycan arrays on aluminum-coated glass slides

scientific article

Glycan arrays: biological and medical applications

scientific article published on February 2008

Glycan microarray of Globo H and related structures for quantitative analysis of breast cancer

scholarly article

Glycans Function as Anchors for Antibodies and Help Drive HIV Broadly Neutralizing Antibody Development

scientific article published on 8 September 2017

Glycans Function as Anchors for Antibodies and Help Drive HIV Broadly Neutralizing Antibody Development

scientific article published in November 2017

Glycans on influenza hemagglutinin affect receptor binding and immune response

scientific article

Glycoengineering of antibody (Herceptin) through yeast expression and in vitro enzymatic glycosylation

scientific article published on 8 January 2018

Glycolipid GD3 and GD3 synthase are key drivers for glioblastoma stem cells and tumorigenicity

scientific article published on 03 May 2016

Glycolipids as immunostimulating agents

scientific article published on 13 October 2007

Glycopeptide mimetics recapitulate high-mannose-type oligosaccharide binding and function.

scientific article published on 16 March 2015

Glycoprotein B7-H3 overexpression and aberrant glycosylation in oral cancer and immune response

scientific article

HA-pseudotyped retroviral vectors for influenza antagonist screening

scientific article

HIV-1 protease: mechanism and drug discovery

scientific article (publication date: 7 January 2003)

Hemagglutinin-neuraminidase balance confers respiratory-droplet transmissibility of the pandemic H1N1 influenza virus in ferrets

scientific article

Hierarchical and Programmable One-Pot Oligosaccharide Synthesis

scientific article published on 06 September 2019

Hierarchical and programmable one-pot synthesis of oligosaccharides

scientific article published in Nature Communications

High-throughput identification of antibacterials against methicillin-resistant Staphylococcus aureus (MRSA) and the transglycosylase

scientific article

High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity

scientific article

High-throughput identification of fucosyltransferase inhibitors using carbohydrate microarrays

scientific article

Highly alpha-selective sialyl phosphate donors for efficient preparation of natural sialosides

scientific article published in February 2010

Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity

scientific article

Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design

scientific article published on November 2015

Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia.

scientific article published on 30 April 2007

Identification of novel anthrax lethal factor inhibitors generated by combinatorial Pictet-Spengler reaction followed by screening in situ

scientific article published on 01 June 2005

Iminosugar C-glycoside analogues of α-D-GlcNAc-1-phosphate: synthesis and bacterial transglycosylase inhibition

scientific article

Immunization of fucose-containing polysaccharides from Reishi mushroom induces antibodies to tumor-associated Globo H-series epitopes

scientific article published on August 2013

Immunogenicity study of Globo H analogues with modification at the reducing or nonreducing end of the tumor antigen

scientific article published on 20 November 2014

In vitro evaluation of neuraminidase inhibitors using the neuraminidase-dependent release assay of hemagglutinin-pseudotyped viruses.

scientific article

In vivo selection for the directed evolution of L-rhamnulose aldolase from L-rhamnulose-1-phosphate aldolase (RhaD).

scientific article

Infection of Differentiated Porcine Airway Epithelial Cells by Influenza Virus: Differential Susceptibility to Infection by Porcine and Avian Viruses ⬇️

scientific article published on December 9, 2011

Influenza A surface glycosylation and vaccine design

scientific article published on 27 December 2016

Influenza virus neuraminidase regulates host CD8+ T-cell response in mice

scientific article published on 08 December 2020

Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters

scientific article published in September 2005

Intramolecular ion-pair prodrugs of zanamivir and guanidino-oseltamivir

scientific article

Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria

scientific article

Investigation of SSEA-4 Binding Protein in Breast Cancer Cells ⬇️

scientific article published on April 12, 2013

Iron oxide/gold core/shell nanoparticles for ultrasensitive detection of carbohydrate-protein interactions

scientific article published in September 2009

Isofagomine- and 2,5-anhydro-2,5-imino-D-glucitol-based glucocerebrosidase pharmacological chaperones for Gaucher disease intervention.

scientific article published on January 2007

Latifolicinin A from a Fermented Soymilk Product and the Structure-Activity Relationship of Synthetic Analogues as Inhibitors of Breast Cancer Cell Growth

scientific article published on 24 October 2015

Matrix-assisted laser desorption/ionization mass spectrometry of polysaccharides with 2',4',6'-trihydroxyacetophenone as matrix

scientific article

Mechanistic studies of beta-arylsulfotransferase IV

scientific article

Microtiter plate based chemistry and in situ screening: a useful approach for rapid inhibitor discovery

scientific article published on 22 March 2006

Model system for high-throughput screening of novel human immunodeficiency virus protease inhibitors in Escherichia coli

scientific article published in July 2004

Modular synthesis of N-glycans and arrays for the hetero-ligand binding analysis of HIV antibodies

scientific article published on 7 March 2016

Modulation of Substrate Specificities of d-Sialic Acid Aldolase through Single Mutations of Val-251 ⬇️

scientific article published on January 26, 2011

N-glycosylation of enhanced aromatic sequons to increase glycoprotein stability

scientific article published on 3 February 2012

NKT cells prevent chronic joint inflammation after infection with Borrelia burgdorferi

scholarly article

Natural Sphingomonas glycolipids vary greatly in their ability to activate natural killer T cells

scientific article

Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria

scientific article published on 20 August 2006

New continuous fluorometric assay for bacterial transglycosylase using Förster resonance energy transfer.

scientific article

New development of glycan arrays.

scientific article

Novel efficient routes to heparin monosaccharides and disaccharides achieved via regio- and stereoselective glycosidation

scientific article published on 01 March 2004

Novel five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: new structures for antivirals and osteoarthritis.

scientific article published on January 2006

O-GlcNAcylation regulates EZH2 protein stability and function

scientific article

O-GlcNAcylation regulates the stability and enzymatic activity of the histone methyltransferase EZH2.

scientific article published on 25 June 2018

Oligosaccharide Synthesis and Translational Innovation

scientific article published on 18 February 2019

One-pot synthesis of L-Fructose using coupled multienzyme systems based on rhamnulose-1-phosphate aldolase

scientific article published in August 2003

Oseltamivir hydroxamate and acyl sulfonamide derivatives as influenza neuraminidase inhibitors

scientific article published on December 2014

Peramivir Phosphonate Derivatives as Influenza Neuraminidase Inhibitors

scientific article published on 11 May 2016

Phenyl Glycolipids with Different Glycosyl Groups Exhibit Marked Differences in Murine and Human iNKT Cell Activation

scientific article published on 26 October 2016

Plasma proteome of severe acute respiratory syndrome analyzed by two-dimensional gel electrophoresis and mass spectrometry

scholarly article

Polysaccharides of Ganoderma lucidum alter cell immunophenotypic expression and enhance CD56+ NK-cell cytotoxicity in cord blood

scientific article

Potent adjuvant effects of novel NKT stimulatory glycolipids on hemagglutinin based DNA vaccine for H5N1 influenza virus.

scientific article

Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids

scholarly article

Preparation of Aluminum Oxide-Coated Glass Slides for Glycan Microarrays.

scientific article published on 3 November 2016

Printed covalent glycan array for ligand profiling of diverse glycan binding proteins

scientific article

Programmable One-Pot Glycosylation ⬇️

scientific article published on January 1, 2011

Programmable One-Pot Synthesis of Heparin Pentasaccharide Fondaparinux

scientific article published on 04 June 2020

Programmable One-Pot Synthesis of Oligosaccharides

scientific article published on 06 September 2019

Programmable one-pot synthesis of heparin pentasaccharides enabling access to regiodefined sulfate derivatives

scientific article published on 03 July 2018

Programmable reactivity-based one-pot oligosaccharide synthesis

scientific article

Protein microarray using alpha-amino acids as metal tags on chips

scientific article published in March 2005

Protein native-state stabilization by placing aromatic side chains in N-glycosylated reverse turns

scientific article published on February 2011

Purine-Type Compounds Induce Microtubule Fragmentation and Lung Cancer Cell Death through Interaction with Katanin.

scientific article

Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: determination of surface and solution dissociation constants

scientific article

Quantitative microarray analysis of intact glycolipid-CD1d interaction and correlation with cell-based cytokine production

scientific article published on 20 August 2008

Rapid characterization of sugar-binding specificity by in-solution proximity binding with photosensitizers

scientific article published on 16 February 2011

Rapid discovery of potent sulfotransferase inhibitors by diversity-oriented reaction in microplates followed by in situ screening

scientific article

Rapid diversity-oriented synthesis in microtiter plates for in situ screening: discovery of potent and selective alpha-fucosidase inhibitors.

scientific article published in October 2003

Rapid preparation of mycobacterium N-glycolyl Lipid I and Lipid II derivatives: a biocatalytic approach.

scientific article

Reactivity-based one-pot synthesis of a Lewis Y carbohydrate hapten: a colon-rectal cancer antigen determinant

scientific article published on 01 November 2002

Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody

scientific article published on February 2004

Reactivity-based one-pot total synthesis of fucose GM1 oligosaccharide: a sialylated antigenic epitope of small-cell lung cancer

scientific article

Recognition of bacterial glycosphingolipids by natural killer T cells

scientific article published in March 2005

Regioselective glycosylation of neamine core: a facile entry to kanamycin B related analogues.

scientific article

Regioselective synthesis of di-C-glycosylflavones possessing anti-inflammation activities.

scientific article published on 19 August 2010

Reishi Polysaccharides Induce Immunoglobulin Production through the TLR4/TLR2-mediated Induction of Transcription Factor Blimp-1

scientific article published on 23 June 2006

Residues Comprising the Enhanced Aromatic Sequon Influence Protein N-glycosylation Efficiency.

scientific article

Reversible and in situ formation of organic arsenates and vanadates as organic phosphate mimics in enzymatic reactions: mechanistic investigation of aldol reactions and synthetic applications

article

Role of N-linked glycans in the interactions of recombinant HCV envelope glycoproteins with cellular receptors

scientific article published on 15 May 2014

Screening for HIV protease inhibitors by protection against activity-mediated cytotoxicity in Escherichia coli.

scientific article

Second-generation sugar-assisted ligation: a method for the synthesis of cysteine-containing glycopeptides

scientific article published on 01 January 2007

Sequence-constructive SELEX: a new strategy for screening DNA aptamer binding to Globo H.

scientific article

Signaling pathway of globo-series glycosphingolipids and β1,3-galactosyltransferase V (β3GalT5) in breast cancer

scientific article published on 11 February 2019

Small molecules targeting severe acute respiratory syndrome human coronavirus

scholarly article

Solid-phase synthesis of peptide and glycopeptide thioesters through side-chain-anchoring strategies

scientific article

Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses

scientific article published on 6 November 2005

Stable Benzotriazole Esters as Mechanism-Based Inactivators of the Severe Acute Respiratory Syndrome 3CL Protease

scientific article published on 01 March 2006

Stage-specific embryonic antigen-3 (SSEA-3) and β3GalT5 are cancer specific and significant markers for breast cancer stem cells

scientific article published on 17 December 2015

Stage-specific embryonic antigen-4 as a potential therapeutic target in glioblastoma multiforme and other cancers

scientific article published on 03 February 2014

Strategies for the preparation of homogenous glycoproteins

scientific article published on 13 October 2006

Structural Evaluation of Potent NKT Cell Agonists: Implications for Design of Novel Stimulatory Ligands

scientific article

Structural and Energetic Basis of Carbohydrate–Aromatic Packing Interactions in Proteins

scientific article

Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity

scientific article

Structure and bioactivity of the polysaccharides in medicinal plant Dendrobium huoshanense.

scientific article published on 24 April 2008

Structure-based design and synthesis of highly potent SARS-CoV 3CL protease inhibitors

scientific article published on 01 September 2007

Structure-based discovery of glycolipids for CD1d-mediated NKT cell activation: tuning the adjuvant versus immunosuppression activity

scientific article published on July 2006

Structure-based mutagenesis approaches toward expanding the substrate specificity of D-2-deoxyribose-5-phosphate aldolase

scientific article published on January 2003

Structure-guided development of purine amide, hydroxamate, and amidoxime for the inhibition of non-small cell lung cancer

scientific article published on 22 July 2019

Studies on the immuno-modulating and anti-tumor activities of Ganoderma lucidum (Reishi) polysaccharides

scientific article published on 01 November 2004

Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities

scientific article published on April 2002

Substrate Preference and Interplay of Fucosyltransferase 8 and N-Acetylglucosaminyltransferases

scientific article

Subtilisin-catalyzed glycopeptide condensation

scientific article published on 01 January 2004

Sugar arrays in microtiter plates

scientific article published in January 2003

Sugar-assisted glycopeptide ligation

scientific article published in May 2006

Sugar-assisted glycopeptide ligation with complex oligosaccharides: scope and limitations

scientific article published on 13 August 2008

Sugar-assisted ligation in glycoprotein synthesis

scientific article published on 25 May 2007

Sugar-assisted ligation of N-linked glycopeptides with broad sequence tolerance at the ligation junction

scientific article

Sulfatases: structure, mechanism, biological activity, inhibition, and synthetic utility

scientific article published in November 2004

Sulfotransferases: structure, mechanism, biological activity, inhibition, and synthetic utility

scientific article

Suppression of Drug-Resistant Non-Small-Cell Lung Cancer with Inhibitors Targeting Minichromosomal Maintenance Protein

scientific article published on 17 March 2020

Survey of immune-related, mannose/fucose-binding C-type lectin receptors reveals widely divergent sugar-binding specificities ⬇️

scientific article published on November 26, 2010

Synergistic effect of zanamivir-porphyrin conjugates on inhibition of neuraminidase and inactivation of influenza virus

scientific article published in August 2009

Synthesis and bioactivity of β-(1→4)-linked oligomannoses and partially acetylated derivatives.

scientific article published on 18 June 2013

Synthesis and evaluation of a new fluorescent transglycosylase substrate: lipid II-based molecule possessing a dansyl-C20 polyprenyl moiety

scientific article published in April 2010

Synthesis and evaluation of acyl-chain- and galactose-6''-modified analogues of α-GalCer for NKT cell activation

scientific article

Synthesis and evaluation of general mechanism-based inhibitors of sulfatases based on (difluoro)methyl phenyl sulfate and cyclic phenyl sulfamate motifs

scientific article published on 11 October 2006

Synthesis and high-throughput screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritis

scientific article

Synthesis and human NKT cell stimulating properties of 3-O-sulfo-alpha/beta-galactosylceramides

scientific article published in April 2005

Synthesis and vaccine evaluation of the tumor-associated carbohydrate antigen RM2 from prostate cancer

scientific article published on 17 July 2013

Synthesis of Modular Building Blocks using Glycosyl Phosphate Donors for the Construction of Asymmetric N-Glycans

scientific article published on 27 August 2018

Synthesis of N-acetyllactosamine derivatives with variation in the aglycon moiety for the study of inhibition of sialyl Lewis x expression

scientific article published on September 2003

Synthesis of Neisseria meningitidis serogroup W135 capsular oligosaccharides for immunogenicity comparison and vaccine development

scientific article published on 10 July 2013

Synthesis of Sialidase-Resistant Oligosaccharide and Antibody Glycoform Containing α2,6-Linked 3Fax-Neu5Ac

scientific article published on 15 April 2019

Synthesis of alpha-galactosyl ceramide, a potent immunostimulatory agent

scientific article

Synthesis of sugar arrays in microtiter plate

scientific article

Synthesis of tamiflu and its phosphonate congeners possessing potent anti-influenza activity.

scientific article published on 12 September 2007

Synthesis of α-galactosyl ceramide and the related glycolipids for evaluation of their activities on mouse splenocytes

article published in 2005

Synthetic Carbohydrate Chemistry and Translational Medicine

scientific article published on 30 October 2020

Tailored glycoproteomics and glycan site mapping using saccharide-selective bioorthogonal probes

scientific article

Tamiphosphor monoesters as effective anti-influenza agents

scientific article published on 2 May 2014

Targeting RNAs with tobramycin analogues

scientific article published in December 2004

Targeting the Bacterial Transglycosylase: Antibiotic Development from a Structural Perspective

scientific article published on 08 July 2019

Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN

scientific article

Tetrabutylammonium fluoride-assisted rapid N9-alkylation on purine ring: application to combinatorial reactions in microtiter plates for the discovery of potent sulfotransferase inhibitors in situ

scientific article published in August 2005

Tetrabutylammonium fluoride-mediated rapid alkylation reaction in microtiter plates for the discovery of enzyme inhibitors in situ

scientific article published in December 2005

The 2-anilino-4-amino-5-aroylthiazole-type compound AS7128 inhibits lung cancer growth through decreased iASPP and p53 interaction.

scientific article published on 29 December 2017

The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate

scientific article published on June 2016

The Immunologically Active Oligosaccharides Isolated from Wheatgrass Modulate Monocytes via Toll-like Receptor-2 Signaling ⬇️

scientific article published on April 29, 2013

The Thioglycoside and Glycosyl Phosphite of 5-Azido Sialic Acid: Excellent Donors for the alpha-Glycosylation of Primary Hydroxy Groups This research was supported by Academia Sinica (Taipei) and the NIH (USA)

scientific article published on 01 August 2001

The Thioglycoside and Glycosyl Phosphite of 5-Azido Sialic Acid: Excellent Donors for the α-Glycosylation of Primary Hydroxy Groups

scientific article published in August 2001

The core trisaccharide of an N-linked glycoprotein intrinsically accelerates folding and enhances stability

scholarly article

The immunologically active oligosaccharides isolated from wheatgrass modulate monocytes via Toll-like receptor-2 signaling

scientific article published on May 2015

The interaction of lipopolysaccharide with membrane receptors on macrophages pretreated with extract of Reishi polysaccharides measured by optical tweezers

scientific article published in August 2007

The lifespan-promoting effect of acetic acid and Reishi polysaccharide

scientific article published on 6 September 2009

The multifaceted effects of polysaccharides isolated from Dendrobium huoshanense on immune functions with the induction of interleukin-1 receptor antagonist (IL-1ra) in monocytes

scientific article

The surface carbohydrates of the Echinococcus granulosus larva interact selectively with the rodent Kupffer cell receptor

scientific article published in November 2013

Three-Step Synthesis of Sialic Acids and Derivatives

scientific article (publication date: 13 November 2006)

Total synthesis of polyprenyl N-glycolyl lipid II as a mycobacterial transglycosylase substrate

article by Fan-Chun Meng et al published 13 September 2011 in Organic Letters

Toward Automated Oligosaccharide Synthesis ⬇️

scientific article published on November 30, 2011

Toward a Carbohydrate-Based HIV-1 Vaccine

article

Towards new antibiotics targeting bacterial transglycosylase: Synthesis of a Lipid II analog as stable transition-state mimic inhibitor

scientific article published on 15 March 2018

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

scientific article

Trisaccharide Sulfate and Its Sulfonamide as an Effective Substrate and Inhibitor of Human Endo-O-sulfatase-1

scientific article published on 04 March 2020

Undecaprenyl Phosphate Phosphatase Activity of Undecaprenol Kinase Regulates the Lipid Pool in Gram-Positive Bacteria.

scientific article published on 5 September 2017

Unprecedented Role of Hybrid N-Glycans as Ligands for HIV-1 Broadly Neutralizing Antibodies

scientific article published on 26 March 2018

Vaccination of monoglycosylated hemagglutinin induces cross-strain protection against influenza virus infections.

scientific article

Vaccine design of hemagglutinin glycoprotein against influenza ⬇️

scientific article published on September 1, 2011

Vancomycin analogues containing monosaccharides exhibit improved antibiotic activity: a combined one-pot enzymatic glycosylation and chemical diversification strategy

scientific article published in September 2006

α-Galactosylceramide but not phenyl-glycolipids induced NKT cell anergy and IL-33-mediated myeloid-derived suppressor cell accumulation via upregulation of egr2/3.

scientific article published on 24 January 2014

α-Glycosylation byd-Glucosamine-Derived Donors: Synthesis of Heparosan and Heparin Analogues That Interact with Mycobacterial Heparin-Binding Hemagglutinin ⬇️

scientific article published on May 15, 2012

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