List of works - Melissa C. Skala

Autofluorescence flow sorting of breast cancer cell metabolism

scientific article

Autofluorescence imaging of 3D tumor-macrophage microscale cultures resolves spatial and temporal dynamics of macrophage metabolism

scientific article published on 22 October 2020

Blind deconvolution estimation of fluorescence measurements through quadratic programming.

scientific article published on July 2015

Classification of T-cell activation via autofluorescence lifetime imaging

scientific article published on 27 July 2020

Classifying T cell activity in autofluorescence intensity images with convolutional neural networks

scientific article published on 15 December 2019

Collagen density and alignment in responsive and resistant trastuzumab-treated breast cancer xenografts

scientific article

Combined hyperspectral and spectral domain optical coherence tomography microscope for noninvasive hemodynamic imaging

scientific article

Comparison of a physical model and principal component analysis for the diagnosis of epithelial neoplasias in vivo using diffuse reflectance spectroscopy

scientific article published on June 2007

Copolymer-Mediated Cell Aggregation Promotes a Proangiogenic Stem Cell Phenotype In Vitro and In Vivo.

scientific article published on 26 September 2016

Cross-sectional tracking of particle motion in evaporating drops: flow fields and interfacial accumulation

scientific article

Deconvolution of fluorescence lifetime imaging microscopy by a library of exponentials

scientific article published on September 2015

Depth-resolved analytical model and correction algorithm for photothermal optical coherence tomography

scientific article published on 16 June 2016

Drug response in organoids generated from frozen primary tumor tissues

scientific article

Dual pH- and temperature-responsive microparticles for protein delivery to ischemic tissues

scientific article

Dual-modality photothermal optical coherence tomography and magnetic-resonance imaging of carbon nanotubes

scientific article published on March 2012

Dysfunctional BMPR2 signaling drives an abnormal endothelial requirement for glutamine in pulmonary arterial hypertension

scientific article

Effects of culture method on response to EGFR therapy in head and neck squamous cell carcinoma cells

scientific article published on 28 August 2019

Ex vivo optical metabolic measurements from cultured tissue reflect in vivo tissue status

scientific article

High-throughput measurements of the optical redox ratio using a commercial microplate reader

scientific article

In Vivo Autofluorescence Imaging of Tumor Heterogeneity in Response to Treatment.

scientific article published on December 2015

In vivo hyperspectral imaging of microvessel response to trastuzumab treatment in breast cancer xenografts.

scientific article

In vivo imaging of nanoparticle delivery and tumor microvasculature with multimodal optical coherence tomography

scientific article

In vivo multiphoton fluorescence lifetime imaging of protein-bound and free nicotinamide adenine dinucleotide in normal and precancerous epithelia

scientific article published on March 2007

In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia

scholarly article

In vivo photothermal optical coherence tomography of endogenous and exogenous contrast agents in the eye.

scientific article published on 23 August 2017

Innate immune cell response to host-parasite interaction in a human intestinal tissue microphysiological system

scientific article published on 06 May 2022

Investigation of fiber-optic probe designs for optical spectroscopic diagnosis of epithelial pre-cancers.

scientific article

Longitudinal optical imaging of tumor metabolism and hemodynamics

scientific article

Metabolic Imaging of Head and Neck Cancer Organoids

scientific article

Metabolomics revealed the influence of breast cancer on lymphatic endothelial cell metabolism, metabolic crosstalk, and lymphangiogenic signaling in co-culture

scientific article published on 04 December 2020

Microfluidic Tumor-on-a-Chip Model to Study Tumor Metabolic Vulnerability

scientific article published on 28 November 2020

Multiphoton microscopy of endogenous fluorescence differentiates normal, precancerous, and cancerous squamous epithelial tissues

scientific article

Multiphoton redox ratio imaging for metabolic monitoring in vivo

scientific article

Optical Imaging of Drug-Induced Metabolism Changes in Murine and Human Pancreatic Cancer Organoids Reveals Heterogeneous Drug Response.

scientific article published on 22 October 2015

Optical imaging of metabolism in HER2 overexpressing breast cancer cells

scientific article published on 9 December 2011

Optical metabolic imaging identifies glycolytic levels, subtypes, and early-treatment response in breast cancer

scientific article published on October 2013

Optical metabolic imaging of treatment response in human head and neck squamous cell carcinoma

scientific article (publication date: 2014)

Optical metabolic imaging quantifies heterogeneous cell populations

scientific article published on 15 January 2015

Patient-Derived Cancer Organoid Cultures to Predict Sensitivity to Chemotherapy and Radiation

scientific article published on 07 June 2019

Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.

scientific article published on 15 January 2018

Photothermal optical coherence tomography of epidermal growth factor receptor in live cells using immunotargeted gold nanospheres

scientific article

Photothermal optical lock-in optical coherence tomography for in vivo imaging

scientific article

Quantifying the vascular response to ischemia with speckle variance optical coherence tomography

scientific article

Quantitative Label-Free Imaging of 3D Vascular Networks Self-Assembled in Synthetic Hydrogels

scientific article published on 19 December 2018

Quantitative optical imaging of primary tumor organoid metabolism predicts drug response in breast cancer.

scientific article

Quantitative optical imaging of vascular response in vivo in a model of peripheral arterial disease

scientific article

ROS-responsive microspheres for on demand antioxidant therapy in a model of diabetic peripheral arterial disease.

scientific article

Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer.

scientific article published on 6 August 2015

Temporal binning of time-correlated single photon counting data improves exponential decay fits and imaging speed

scientific article

The NADH oxidase ENOX1, a critical mediator of endothelial cell radiosensitization, is crucial for vascular development

scientific article

The novel antiangiogenic VJ115 inhibits the NADH oxidase ENOX1 and cytoskeleton-remodeling proteins

scientific article published on 9 October 2012

Three-dimensional molecular imaging with photothermal optical coherence tomography

scientific article

Uncoupling angiogenesis and inflammation in peripheral artery disease with therapeutic peptide-loaded microgels

scientific article published on 22 August 2014

Visualizing Cancer

scientific article published on 01 December 2020

List of works by Melissa C. Skala

Autofluorescence flow sorting of breast cancer cell metabolism

Autofluorescence imaging of 3D tumor-macrophage microscale cultures resolves spatial and temporal dynamics of macrophage metabolism

Blind deconvolution estimation of fluorescence measurements through quadratic programming.

Classification of T-cell activation via autofluorescence lifetime imaging

Classifying T cell activity in autofluorescence intensity images with convolutional neural networks

Collagen density and alignment in responsive and resistant trastuzumab-treated breast cancer xenografts

Combined hyperspectral and spectral domain optical coherence tomography microscope for noninvasive hemodynamic imaging

Comparison of a physical model and principal component analysis for the diagnosis of epithelial neoplasias in vivo using diffuse reflectance spectroscopy

Copolymer-Mediated Cell Aggregation Promotes a Proangiogenic Stem Cell Phenotype In Vitro and In Vivo.

Cross-sectional tracking of particle motion in evaporating drops: flow fields and interfacial accumulation

Deconvolution of fluorescence lifetime imaging microscopy by a library of exponentials

Depth-resolved analytical model and correction algorithm for photothermal optical coherence tomography

Drug response in organoids generated from frozen primary tumor tissues

Dual pH- and temperature-responsive microparticles for protein delivery to ischemic tissues

Dual-modality photothermal optical coherence tomography and magnetic-resonance imaging of carbon nanotubes

Dysfunctional BMPR2 signaling drives an abnormal endothelial requirement for glutamine in pulmonary arterial hypertension

Effects of culture method on response to EGFR therapy in head and neck squamous cell carcinoma cells

Ex vivo optical metabolic measurements from cultured tissue reflect in vivo tissue status

High-throughput measurements of the optical redox ratio using a commercial microplate reader

In Vivo Autofluorescence Imaging of Tumor Heterogeneity in Response to Treatment.

In vivo hyperspectral imaging of microvessel response to trastuzumab treatment in breast cancer xenografts.

In vivo imaging of nanoparticle delivery and tumor microvasculature with multimodal optical coherence tomography

In vivo multiphoton fluorescence lifetime imaging of protein-bound and free nicotinamide adenine dinucleotide in normal and precancerous epithelia

In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia

In vivo photothermal optical coherence tomography of endogenous and exogenous contrast agents in the eye.

Innate immune cell response to host-parasite interaction in a human intestinal tissue microphysiological system

Investigation of fiber-optic probe designs for optical spectroscopic diagnosis of epithelial pre-cancers.

Longitudinal optical imaging of tumor metabolism and hemodynamics

Metabolic Imaging of Head and Neck Cancer Organoids

Metabolomics revealed the influence of breast cancer on lymphatic endothelial cell metabolism, metabolic crosstalk, and lymphangiogenic signaling in co-culture

Microfluidic Tumor-on-a-Chip Model to Study Tumor Metabolic Vulnerability

Multiphoton microscopy of endogenous fluorescence differentiates normal, precancerous, and cancerous squamous epithelial tissues

Multiphoton redox ratio imaging for metabolic monitoring in vivo

Optical Imaging of Drug-Induced Metabolism Changes in Murine and Human Pancreatic Cancer Organoids Reveals Heterogeneous Drug Response.

Optical imaging of metabolism in HER2 overexpressing breast cancer cells

Optical metabolic imaging identifies glycolytic levels, subtypes, and early-treatment response in breast cancer

Optical metabolic imaging of treatment response in human head and neck squamous cell carcinoma

Optical metabolic imaging quantifies heterogeneous cell populations

Patient-Derived Cancer Organoid Cultures to Predict Sensitivity to Chemotherapy and Radiation

Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.

Photothermal optical coherence tomography of epidermal growth factor receptor in live cells using immunotargeted gold nanospheres

Photothermal optical lock-in optical coherence tomography for in vivo imaging

Quantifying the vascular response to ischemia with speckle variance optical coherence tomography

Quantitative Label-Free Imaging of 3D Vascular Networks Self-Assembled in Synthetic Hydrogels

Quantitative optical imaging of primary tumor organoid metabolism predicts drug response in breast cancer.

Quantitative optical imaging of vascular response in vivo in a model of peripheral arterial disease

ROS-responsive microspheres for on demand antioxidant therapy in a model of diabetic peripheral arterial disease.

Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer.

Temporal binning of time-correlated single photon counting data improves exponential decay fits and imaging speed

The NADH oxidase ENOX1, a critical mediator of endothelial cell radiosensitization, is crucial for vascular development

The novel antiangiogenic VJ115 inhibits the NADH oxidase ENOX1 and cytoskeleton-remodeling proteins

Three-dimensional molecular imaging with photothermal optical coherence tomography

Uncoupling angiogenesis and inflammation in peripheral artery disease with therapeutic peptide-loaded microgels

Visualizing Cancer