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List of works by Lucio Ildebrando Cocco

Advances in targeting signal transduction pathways

scientific article

Ankrd2/ARPP is a novel Akt2 specific substrate and regulates myogenic differentiation upon cellular exposure to H(2)O(2)

scientific article

Cell signaling pathways in autosomal-dominant leukodystrophy (ADLD): the intriguing role of the astrocytes

scientific article published on 09 October 2020

Clusterin enhances AKT2-mediated motility of normal and cancer prostate cells through a PTEN and PHLPP1 circuit

scientific article published on 22 November 2018

Critical Roles of EGFR Family Members in Breast Cancer and Breast Cancer Stem Cells: Targets for Therapy

scientific article published on 4 March 2016

Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention

scientific article

Diverse roles of GSK-3: tumor promoter-tumor suppressor, target in cancer therapy

scientific article published on 08 October 2013

Effects of mutations in Wnt/β-catenin, hedgehog, Notch and PI3K pathways on GSK-3 activity-Diverse effects on cell growth, metabolism and cancer

scientific article published on 06 September 2016

Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs

scientific article published on 12 June 2017

GSK-3 as potential target for therapeutic intervention in cancer

scientific article

Gingival Stromal Cells as an In Vitro Model: Cannabidiol Modulates Genes Linked With Amyotrophic Lateral Sclerosis

scientific article published on 7 October 2016

Impact of phospholipase C β1 in glioblastoma: a study on the main mechanisms of tumor aggressiveness

scientific article published on 18 March 2022

Involvement of Akt and mTOR in chemotherapeutic- and hormonal-based drug resistance and response to radiation in breast cancer cells

scientific article published on September 2011

Lamin A Ser404 is a nuclear target of Akt phosphorylation in C2C12 cells

scientific article published on 23 September 2008

Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response

scientific article published on September 2012

Novel approaches to target cancer initiating cells-eliminating the root of the cancer

scientific article published on January 2012

Novel roles of androgen receptor, epidermal growth factor receptor, TP53, regulatory RNAs, NF-kappa-B, chromosomal translocations, neutrophil associated gelatinase, and matrix metalloproteinase-9 in prostate cancer and prostate cancer stem cells

scientific article

Nuclear Phospholipase C isoenzyme imbalance leads to pathologies in brain, hematologic, neuromuscular and fertility disorders

scientific article published on 04 October 2018

Nuclear translocation of PKCα isoenzyme is involved in neurogenic commitment of human neural crest-derived periodontal ligament stem cells

scientific article published on 28 July 2016

Phosphoinositide-phospholipase C beta1 mono-allelic deletion is associated with myelodysplastic syndromes evolution into acute myeloid leukemia.

scientific article

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance

scientific article

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health

scientific article published on March 2011

Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS.

scientific article published on 10 September 2009

Roles of EGFR and KRAS and their downstream signaling pathways in pancreatic cancer and pancreatic cancer stem cells

scientific article published on 17 July 2015

Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells

scientific article

Roles of NGAL and MMP-9 in the tumor microenvironment and sensitivity to targeted therapy

scientific article published on 13 August 2015

Roles of signaling pathways in drug resistance, cancer initiating cells and cancer progression and metastasis

scientific article

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging

scientific article

Targeting breast cancer initiating cells: advances in breast cancer research and therapy

scientific article

Targeting the cancer initiating cell: the ultimate target for cancer therapy.

scientific article published on January 2012

The therapeutic potential of mTOR inhibitors in breast cancer

scientific article published on 5 April 2016

Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways.

scientific article

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