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List of works by Susan J Little

"My Death Will Not [Be] in Vain": Testimonials from Last Gift Rapid Research Autopsy Study Participants Living with HIV at the End of Life

scientific article published on 25 May 2020

"[It] is now my responsibility to fulfill that wish:" Clinical and rapid autopsy staff members' experiences and perceptions of HIV reservoir research at the end of life

scientific article published on 18 November 2020

1961. Grindr™ on Screen Activity on iPhones Correlates with HIV Risk and Substance Use in Men Who Have Sex with Men, San Diego

A Simple Symptom Score for Acute HIV Infection in a San Diego Community Based Screening Program

scientific article published on 25 December 2017

A combined screening platform for HIV treatment failure and resistance

scientific article

A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infection

scientific article published on 15 August 2006

A practical online tool to estimate antiretroviral coverage for HIV infected and susceptible populations needed to reduce local HIV epidemics.

scientific article published on 24 June 2016

A public health model for the molecular surveillance of HIV transmission in San Diego, California

scientific article published on January 2009

A randomized controlled clinical trial on the impact of CCR5 blockade with maraviroc in early infection on T-cell dynamics

scientific article

Addressing ethical challenges in US-based HIV phylogenetic research

scientific article published on 11 June 2020

Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement

scientific article published on 01 August 2018

Antiretroviral drug resistance and risk behavior among recently HIV-infected men who have sex with men.

scientific article

Antiretroviral therapy in acute and recent HIV infection: a prospective multicenter stratified trial of intentionally interrupted treatment

scientific article

Antiretroviral-drug resistance among patients recently infected with HIV.

scientific article published in August 2002

Associations between phylogenetic clustering and HLA profile among HIV-infected individuals in San Diego, California.

scientific article

Associations between substance use, erectile dysfunction medication and recent HIV infection among men who have sex with men.

scientific article published on 7 December 2007

Associations between virologic and immunologic dynamics in blood and in the male genital tract.

scientific article published on 23 November 2011

Asymptomatic CMV Replication During Early Human Immunodeficiency Virus (HIV) Infection Is Associated With Lower CD4/CD8 Ratio During HIV Treatment.

scientific article published on 6 September 2016

Attitudes and Preferences Regarding the Use of Rapid Self-Testing for Sexually Transmitted Infections and HIV in San Diego Area Men Who Have Sex With Men

article

Behaviors of Recently HIV-Infected Men Who Have Sex With Men in the Year Postdiagnosis: Effects of Drug Use and Partner Types ⬇️

scientific article published on February 1, 2011

Biometric Registration to an HIV Research Study may Deter Participation

scientific article published on 07 August 2020

CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1-infected individuals

scientific article published on 30 March 2008

CD4/CD8 Cell Ratio in Acute HIV Infection and the Impact of Early Antiretroviral Therapy

scientific article published on 3 May 2016

Can research at the end of life be a useful tool to advance HIV cure?

scientific article published on 14 October 2016

Cell-Associated Viral RNA Expression during Acute Infection with HIV Type 1 ⬇️

scientific article published on September 1, 1998

Characteristics of recently HIV-infected men who use the Internet to find male sex partners and sexual practices with those partners

scientific article published in December 2006

Characterization of HIV Transmission in South-East Austria

scientific article

Characterization of human immunodeficiency virus type 1 (HIV-1) envelope variation and neutralizing antibody responses during transmission of HIV-1 subtype B.

scientific article

Characterizing the multiplicity of HIV founder variants during sexual transmission among MSM.

scientific article

Clade B HIV-1 superinfection with wild-type virus after primary infection with drug-resistant clade B virus

scientific article published in May 2003

Clear Links Between Starting Methamphetamine and Increasing Sexual Risk Behavior: A Cohort Study Among Men Who Have Sex With Men.

scientific article published on 2 November 2015

Clinical management of acute HIV infection: best practice remains unknown

scientific article published on October 2010

Clinical utility of HIV standard genotyping among antiretroviral-naive individuals with unknown duration of infection.

scientific article published on 28 December 2006

Clinical, virologic, and immunologic correlates of HIV-1 intraclade B dual infection among men who have sex with men.

scientific article published on January 2012

Colorectal Disorders in Acute Human Immunodeficiency Virus Infection: A Case Series.

scientific article published on 29 January 2016

Comparison of algorithms that interpret genotypic HIV-1 drug resistance to determine the prevalence of transmitted drug resistance

scientific article published on April 2008

Comparison of methods to detect HIV dual infection

scientific article

Concurrency and HIV transmission network characteristics among MSM with recent HIV infection

scientific article published on 20 September 2016

Controlling the HIV epidemic, without a vaccine!

scientific article published in November 2008

Cost savings associated with testing of antibodies, antigens, and nucleic acids for diagnosis of acute HIV infection

scientific article

Costs per Diagnosis of Acute HIV Infection in Community-based Screening Strategies: A Comparative Analysis of Four Screening Algorithms

scientific article

Cytomegalovirus DNA in semen and blood is associated with higher levels of proviral HIV DNA.

scientific article published on 28 December 2012

Cytomegalovirus replication in semen is associated with higher levels of proviral HIV DNA and CD4+ T cell activation during antiretroviral treatment.

scientific article

Detection of minority resistance during early HIV-1 infection: natural variation and spurious detection rather than transmission and evolution of multiple viral variants.

scientific article

Developing and evaluating comprehensive HIV infection control strategies: issues and challenges

scientific article

Development and validation of the San Diego Early Test Score to predict acute and early HIV infection risk in men who have sex with men.

scientific article

Diagnostic, Infection Timing and Incidence Surveillance Applications of High Dynamic Range Chemiluminescent HIV Immuno-Assay Platforms

article

Differential gene expression in HIV-infected individuals following ART.

scientific article published on 06 August 2013

Distinct cytokine/chemokine network in semen and blood characterize different stages of HIV infection

scientific article published on 10 November 2015

Dual-mixed HIV-1 coreceptor tropism and HIV-associated neurocognitive deficits

scientific article published on October 2013

Dynamics and Dispersal of Local HIV Epidemics Within San Diego and Across The San Diego-Tijuana Border

scientific article published on 20 October 2020

Dynamics of T cell responses in HIV infection

scientific article published on 01 April 2002

Dynamics of total, linear nonintegrated, and integrated HIV-1 DNA in vivo and in vitro

scientific article

Dynamics of viral evolution and neutralizing antibody response after HIV-1 superinfection

scientific article published on 18 September 2013

Early Antiretroviral Therapy Is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations

scientific article

Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1.

scientific article

Emergence of individual HIV-specific CD8 T cell responses during primary HIV-1 infection can determine long-term disease outcome

scientific article

Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy

scientific article published on January 2013

Ensuring privacy in the study of pathogen genetics

scientific article

Ethical considerations for HIV cure-related research at the end of life

article

Ethical issues in HIV phylogenetics and molecular epidemiology

scientific article published on 01 May 2019

Evaluation of an HIV nucleic acid testing program with automated Internet and voicemail systems to deliver results.

scientific article

Evaluation of opt-out inpatient HIV screening at an urban teaching hospital.

scientific article published on 23 January 2017

Evaluation of pooled rapid HIV antibody screening of patients admitted to a San Diego Hospital.

scientific article

Evaluation of the Predictive Potential of the Short Acute Retroviral Syndrome Severity Score for HIV-1 Disease Progression in Individuals With Acute HIV Infection

scientific article published on April 2017

Evidence for Increased T Cell Turnover and Decreased Thymic Output in HIV Infection ⬇️

scientific article published on December 1, 2001

Gene expression before HAART initiation predicts HIV-infected individuals at risk of poor CD4+ T-cell recovery

scientific article

Genetic Network Analysis to Assess the Risk of Human Immunodeficiency Virus Transmission Among Men Who Have Sex With Men Seeking Partners on the Internet

scientific article published on 01 February 2020

Genetic basis of hypersusceptibility to protease inhibitors and low replicative capacity of human immunodeficiency virus type 1 strains in primary infection

scientific article published on March 2004

Greater CD4 T-cell gains after one year of antiretroviral therapy are associated with lower HIV-1 pol replication capacity

GrindrTM Users Take more Risks, but are more Open to HIV Pre-Exposure Prophylaxis: Could this Dating App Provide Platform for HIV Prevention Outreach?

scientific article published on 02 November 2019

Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection

scientific article

HIV Infection Rates and Risk Behavior among Young Men undergoing community-based Testing in San Diego

scientific article published on 16 May 2016

HIV Screening in Emergency Departments: Linkage Works but What About Retention?

scientific article published on 12 December 2020

HIV Transmission Networks in the San Diego-Tijuana Border Region

scientific article

HIV drug resistance acquired through superinfection

scientific article

HIV evolution and escape.

scientific article

HIV superinfection

scientific article

HIV treatment decisions and transmitted drug resistance.

scientific article

HIV-1 clade B pol evolution following primary infection

scientific article

HIV-specific cytotoxic T cells from long-term survivors select a unique T cell receptor

scientific article

Herd Immunity Likely Protected the Men who have Sex with Men in Recent Hepatitis A Outbreak in San Diego CA

scientific article published on 01 March 2019

Herpes simplex virus 2 serostatus and viral loads of HIV-1 in blood and semen as risk factors for HIV transmission among men who have sex with men.

scientific article published on August 2008

Herpes simplex virus type 2 acquisition during recent HIV infection does not influence plasma HIV levels

scientific article published on April 2008

Herpes simplex virus type 2 infection does not influence viral dynamics during early HIV-1 infection

scientific article published on 15 March 2007

Herpes viruses and HIV-1 drug resistance mutations influence the virologic and immunologic milieu of the male genital tract.

scientific article published on January 2013

High-risk behaviors associated with injection drug use among recently HIV-infected men who have sex with men in San Diego, CA.

scientific article

Higher HIV-1 genetic diversity is associated with AIDS and neuropsychological impairment

scientific article

How can we detect HIV during the acute or primary stage of infection?

scientific article published on 19 August 2016

Human APOBEC3 induced mutation of human immunodeficiency virus type-1 contributes to adaptation and evolution in natural infection

scientific article

Human immunodeficiency virus type 1 clade B superinfection: evidence for differential immune containment of distinct clade B strains

scientific article published on January 2005

Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells

scientific article published on 20 May 2009

I wanted it as soon as possible: a qualitative exploration of reactions to access to same-day ART start among participants in San Diego's ART-NET project

scientific article published on 12 November 2019

Identifying the early post-HIV antibody seroconversion period

scientific article

Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection

scientific article

Impact of seminal cytomegalovirus replication on HIV-1 dynamics between blood and semen

scientific article

Impaired Nef function is associated with early control of HIV-1 viremia

scientific article published on 25 June 2014

Impaired replication capacity of acute/early viruses in persons who become HIV controllers

scientific article

Incidence and prevalence of intrasubtype HIV-1 dual infection in at-risk men in the United States.

scientific article

Incidence of HIV superinfection following primary infection.

scientific article

Incorporating metadata in HIV transmission network reconstruction: A machine learning feasibility assessment

scientific article published on 22 September 2021

Increased HIV-1 superinfection risk in carriers of specific human leukocyte antigen alleles

scientific article

Independent assessment of candidate HIV incidence assays on specimens in the CEPHIA repository

scientific article

Infection Staging and Incidence Surveillance Applications of High Dynamic Range Diagnostic Immuno-Assay Platforms

scientific article published on 7 September 2017

Influence of the timing of antiretroviral therapy on the potential for normalization of immune status in human immunodeficiency virus 1-infected individuals

scientific article

Intrasubtype B HIV-1 Superinfection Correlates with Delayed Neutralizing Antibody Response

scientific article published on 14 June 2017

Lack of neutralizing antibody response to HIV-1 predisposes to superinfection.

scientific article published on 7 September 2006

Latently-infected CD4+ T cells are enriched for HIV-1 Tat variants with impaired transactivation activity

scientific article published on 5 March 2009

Lessons learned from the Last Gift study: ethical and practical challenges faced while conducting HIV cure-related research at the end of life

scientific article published in 2022

Long-term persistence of transmitted HIV drug resistance in male genital tract secretions: implications for secondary transmission.

scientific article published on 19 June 2007

Longitudinal Viral Dynamics in Semen During Early HIV Infection.

scientific article published on February 2017

MSM: resurgent epidemics ⬇️

scientific article published on July 1, 2011

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

scientific article published in April 2002

Meta-analysis of the Cepheid Xpert® CT/NG assay for extragenital detection of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections

scientific article published on 01 August 2019

Methamphetamine Use in HIV-infected Individuals Affects T-cell Function and Viral Outcome during Suppressive Antiretroviral Therapy.

scientific article

Modeling the impact of post-diagnosis behavior change on HIV prevalence in Southern California men who have sex with men (MSM).

scientific article published on August 2014

Neurobehavioral Disturbances During Acute and Early HIV Infection

scientific article published on March 2016

Neurocognitive functioning in acute or early HIV infection

scientific article

Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection

scientific article

No Substantial Evidence for Sexual Transmission of Minority HIV Drug Resistance Mutations in Men Who Have Sex with Men.

scientific article

No evidence of posttreatment control after early initiation of antiretroviral therapy

scientific article

Optimizing peptide matrices for identifying T-cell antigens

scientific article published on November 2008

Partner services in adults with acute and early HIV infection

scientific article published on 7 November 2016

Perceptions of Next-of-Kin/Loved Ones about Last Gift Rapid Research Autopsy Study Enrolling People with HIV/AIDS at the End-of-Life: A Qualitative Interview Study

scientific article published on 25 May 2020

Perceptions of molecular epidemiology studies of HIV among stakeholders

scientific article published on 13 December 2017

Persistence of transmitted drug resistance among subjects with primary human immunodeficiency virus infection.

scientific article published on 19 March 2008

Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine

scientific article published on 29 September 2021

Phylogenetic Cluster Analysis: Persons with Undiagnosed Infection Drive HIV Transmission in a Population with High Levels of Virologic Suppression

scientific article published on 08 April 2020

Polyclonal proliferation and apoptosis of CCR5+ T lymphocytes during primary human immunodeficiency virus type 1 infection: regulation by interleukin (IL)-2, IL-15, and Bcl-2.

scientific article published on 15 May 2003

Pre-exposure prophylaxis accessibility research and evaluation (PrEPARE Study)

scientific article

Predictors of virologic response in persons who start antiretroviral therapy during recent HIV infection

scientific article

Prevalence of Transmitted HIV Drug Resistance Among Recently Infected Persons in San Diego, CA 1996-2013.

scientific article

Primary Incidence of Hepatitis C Virus Infection Among HIV-Infected Men Who Have Sex With Men in San Diego, 2000-2015

article

RETRACTED: Investigation of the GeneXpert® CT/NG assay for use with male pharyngeal and rectal swabs

retracted scientific article published on 10 August 2016

Rapid HIV Viral Load Suppression in those Initiating Antiretroviral Therapy at First Visit after HIV Diagnosis

scientific article published on 06 September 2016

Rapid antiretroviral therapy among individuals with acute and early HIV

scientific article published on 10 August 2020

Real-world impact of neurocognitive deficits in acute and early HIV infection

scientific article

Recognition of a defined region within p24 gag by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles

scientific article published on 9 May 2007

Repeat HIV-testing is associated with an increase in behavioral risk among men who have sex with men: a cohort study.

scientific article

Replication of Human Herpesviruses Is Associated with Higher HIV DNA Levels during Antiretroviral Therapy Started at Early Phases of HIV Infection.

scientific article published on 3 February 2016

Reply to Mounzer and DiNubile.

scientific article published on 10 May 2013

Response to Comment on "The Origins of Sexually Transmitted HIV Among Men Who Have Sex with Men"

scientific article

Risk Behavior and Sexually Transmitted Infections Among Transgender Women and Men Undergoing Community-Based Screening for Acute and Early HIV Infection in San Diego

scientific article

Risk Factors for Acute and Early HIV Infection Among Men Who Have Sex With Men (MSM) in San Diego, 2008 to 2014: A Cohort Study

scientific article

Risk profile and HIV testing outcomes of women undergoing community-based testing in San Diego 2008-2014.

scientific article published on 06 February 2017

Role of seminal shedding of herpesviruses in HIV Type 1 Transmission

scientific article

Safety and immunogenicity of therapeutic DNA vaccination in individuals treated with antiretroviral therapy during acute/early HIV-1 infection ⬇️

scientific article

Salvage Antiretroviral Therapy: Time for "DeNUKElearization"?

scientific article published on 01 April 2020

Screening for acute HIV infection in community-based settings: Cost-effectiveness and impact on transmissions.

scientific article published on 10 August 2016

Seminal Shedding of CMV and HIV Transmission among Men Who Have Sex with Men.

scientific article published on 7 July 2015

Sex, race, and geographic region influence clinical outcomes following primary HIV-1 infection

scientific article

Sexual Partner Concurrency Among Partners Reported by MSM with Recent HIV Infection

scientific article published on 12 July 2017

Sexual transmission of predicted CXCR4-tropic HIV-1 likely originating from the source partner's seminal cells.

scientific article

Shedding of HIV and human herpesviruses in the semen of effectively treated HIV-1-infected men who have sex with men.

scientific article published on 17 April 2013

Signs or Symptoms of Acute HIV Infection in a Cohort Undergoing Community-Based Screening.

scientific article published on February 2016

Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc.

scientific article

Substance use is a risk factor for neurocognitive deficits and neuropsychiatric distress in acute and early HIV infection

scientific article published on 19 December 2012

Switching to Tenofovir Alafenamide in Elvitegravir-Based Regimens: Pharmacokinetics and Antiviral Activity in Cerebrospinal Fluid

scientific article published on 27 September 2019

Temporal variation in HIV-specific IgG subclass Abs during acute infection differentiates spontaneous controllers from chronic progressors.

scientific article published on 12 December 2017

The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies

scientific article published on 01 November 2018

The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate

scientific article published in PLoS ONE

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

scientific article

The origins of sexually transmitted HIV among men who have sex with men.

scientific article

The prostate as a reservoir for HIV-1.

scientific article published in July 2004

The setpoint study (ACTG A5217): effect of immediate versus deferred antiretroviral therapy on virologic set point in recently HIV-1-infected individuals

scientific article published on 15 December 2011

The use of pooled viral load testing to identify antiretroviral treatment failure

scientific article

The virologic and immunologic effects of cyclosporine as an adjunct to antiretroviral therapy in patients treated during acute and early HIV-1 infection

scientific article

Tolerability and efficacy of PI versus NNRTI-based regimens in subjects receiving HAART during acute or early HIV infection

scientific article

Transmission behaviors of recently HIV-infected men who have sex with men.

scientific article

Transmission fitness of drug-resistant human immunodeficiency virus and the prevalence of resistance in the antiretroviral-treated population

scientific article published on 29 January 2003

Treatment of Acute HIV Infection and the Potential Role of Acutely HIV-Infected Persons in Cure Studies.

scientific article

Treatment of acute HIV-1 infection: are we getting there?

scientific article published on January 2008

Trust and Expectations of Researchers and Public Health Departments for the Use of HIV Molecular Epidemiology

scientific article published on 03 May 2019

Universal HIV and Birth Cohort HCV Screening in San Diego Emergency Departments

scientific article published on 09 October 2019

Unprotected anal intercourse and substance use among men who have sex with men with recent HIV infection.

scientific article published in November 2006

Unprotected anal intercourse and substance use before and after HIV diagnosis among recently HIV-infected men who have sex with men.

scientific article published in June 2007

Upregulation of BST-2/Tetherin by HIV Infection In Vivo.

scientific article published in December 2012

Upregulation of BST-2/Tetherin by HIV infection in vivo

scientific article

Using HIV Sequence and Epidemiologic Data to Assess the Effect of Self-referral Testing for Acute HIV Infection on Incident Diagnoses in San Diego, California

scientific article

Using HIV networks to inform real time prevention interventions

scientific article

Using HIV transmission networks to investigate community effects in HIV prevention trials

scientific article

Using ultradeep pyrosequencing to study HIV-1 coreceptor usage in primary and dual infection.

scientific article published on 18 April 2013

Viral load criteria and threshold optimization to improve HIV incidence assay characteristics

scientific article published on 22 July 2016

Virologic correlates of anti-CMV IgG levels in HIV-1-infected men.

scientific article published on 20 August 2013

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