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List of works by François Mach

"In vivo" imaging of atherosclerosis.

scientific article published on 08 May 2012

2016 European Guidelines on cardiovascular disease prevention in clinical practice

scientific article published on 27 June 2016

4D cardiac imaging at clinical 3.0T provides accurate assessment of murine myocardial function and viability

scientific article

A Short Intervention Followed by an Interactive E-Learning Module to Motivate Medical Students to Enlist as First Responders: Protocol for a Prospective Implementation Study

scientific article published on 06 November 2020

A Short Intervention and an Interactive e-Learning Module to Motivate Medical and Dental Students to Enlist as First Responders: Implementation Study

scientific article published on 18 May 2022

Acipimox reduces circulating levels of insulin and associated neutrophilic inflammation in metabolic syndrome.

scientific article published on 25 January 2011

Alamandine abrogates neutrophil degranulation in atherosclerotic mice

scientific article

Angiotensin II receptor antagonists in acute coronary syndromes

scientific article published on 02 December 2013

Anti-ApoA-1 IgG serum levels predict worse poststroke outcomes

scientific article published on 4 August 2016

Anti-Apolipoprotein A-1 IgG Influences Neutrophil Extracellular Trap Content at Distinct Regions of Human Carotid Plaques

scientific article published on 19 October 2020

Anti-Apolipoprotein A-1 auto-antibodies are active mediators of atherosclerotic plaque vulnerability

Anti-apoA-1 auto-antibodies increase mouse atherosclerotic plaque vulnerability, myocardial necrosis and mortality triggering TLR2 and TLR4

article published in 2015

Anti-apolipoprotein A-1 auto-antibodies as active modulators of atherothrombosis.

scientific article

Atherosclerotic plaque vulnerability is increased in mouse model of lupus

scientific article published on 27 October 2020

Atorvastatin Treatment and Vaccination Efficacy

scientific article published on 04 June 2007

Biological effect of increased maintenance dose of clopidogrel in cardiovascular outpatients and influence of the cytochrome P450 2C19*2 allele on clopidogrel responsiveness

scientific article published on 02 August 2007

CC and CXC chemokines are pivotal mediators of cerebral injury in ischaemic stroke

Cannabinoid receptor type 2 activation in atherosclerosis and acute cardiovascular diseases

scientific article published on January 2014

Cardiomyocyte-Specific JunD Overexpression Increases Infarct Size following Ischemia/Reperfusion Cardiac Injury by Downregulating Sirt3

scientific article published on 13 December 2019

Circulating FABP4 is a prognostic biomarker in patients with acute coronary syndrome but not in asymptomatic individuals

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Comparison of drug-eluting stents with bare metal stents in patients with ST-segment elevation myocardial infarction

scientific article published on 23 February 2012

Coronary artery calcification and cardiovascular risk: the role of RANKL/OPG signalling

scientific article published on 23 May 2010

Cysteine-rich angiogenic inducer 61 (Cyr61): a novel soluble biomarker of acute myocardial injury improves risk stratification after acute coronary syndromes

scientific article

Decreased phosphatidylcholine plasmalogens--A putative novel lipid signature in patients with stable coronary artery disease and acute myocardial infarction

scientific article published on 6 January 2016

Decreased serum PCSK9 levels after ischaemic stroke predict worse outcomes

scientific article published on 19 October 2016

Discovery and refinement of loci associated with lipid levels

scientific article

Effect of statins and non-statin LDL-lowering medications on cardiovascular outcomes in secondary prevention: a meta-analysis of randomized trials

scientific article published on 23 October 2017

Effectiveness, Adherence, and Safety of Evolocumab in a Swiss Multicenter Prospective Observational Study

scientific article published on 18 November 2021

Effects of statin therapy according to plasma high-sensitivity C-reactive protein concentration in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA): a retrospective analysis

scientific article

Eligibility for PCSK9 Inhibitors According to American College of Cardiology (ACC) and European Society of Cardiology/European Atherosclerosis Society (ESC/EAS) Guidelines After Acute Coronary Syndromes

scientific article

Expected impact of applying new 2013 AHA/ACC cholesterol guidelines criteria on the recommended lipid target achievement after acute coronary syndromes

scientific article

Gender and age differences in outcomes of patients with acute coronary syndromes referred for coronary angiography

scientific article published on 05 October 2018

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Gut microbiota-dependent trimethylamine N-oxide in acute coronary syndromes: a prognostic marker for incident cardiovascular events beyond traditional risk factors

scientific article published on 11 January 2017

Guía ESC 2016 sobre prevención de la enfermedad cardiovascular en la práctica clínica

Health utility indexes in patients with acute coronary syndromes

scientific article published on 23 May 2016

Implementation strategies of Systems Medicine in clinical research and home care for cardiovascular disease patients

scientific article published on 03 October 2014

Improved risk stratification of patients with acute coronary syndromes using a combination of hsTnT, NT-proBNP and hsCRP with the GRACE score

scientific article

Incidence, Predictors, and Clinical Impact of Early Prasugrel Cessation in Patients With ST-Elevation Myocardial Infarction

scientific article published on 13 April 2018

Increased Proangiogenic Activity of Mobilized CD34+ Progenitor Cells of Patients With Acute ST-Segment-Elevation Myocardial Infarction: Role of Differential MicroRNA-378 Expression

scientific article published on 29 December 2016

Inferior vena cava parameters predict re-admission in ischaemic heart failure

Inhibition of nicotinamide phosphoribosyltransferase reduces neutrophil-mediated injury in myocardial infarction

scientific article published on 14 May 2012

Interleukin-1β Mediates Arterial Thrombus Formation via NET-Associated Tissue Factor

scientific article published on 26 November 2019

Intraplaque Expression of C-Reactive Protein Predicts Cardiovascular Events in Patients with Severe Atherosclerotic Carotid Artery Stenosis

scientific article published on 21 September 2016

Left atrial thrombosis in an anticoagulated patient after bioprosthetic valve replacement: Report of a case

scientific article published on January 2014

Leptin/adiponectin ratio predicts poststroke neurological outcome

scientific article published on 18 September 2015

Low statin use in adults hospitalized with acute coronary syndrome

scientific article

New evidence for nicotinic acid treatment to reduce atherosclerosis

scientific article published on October 2010

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice

scientific article published on 7 November 2013

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

scientific article

Occurrence and Impact of Time Delay to Primary Percutaneous Coronary Intervention in Patients With ST-Segment Elevation Myocardial Infarction

scientific article published on 27 October 2017

Optimal Timing of Invasive Coronary Angiography following NSTEMI

scientific article published on 03 March 2020

Oxaprozin-induced apoptosis on CD40 ligand-treated human primary monocytes is associated with the modulation of defined intracellular pathways

scientific article published on 10 August 2009

Pathophysiology and Treatments of Oxidative Injury in Ischemic Stroke: Focus on the Phagocytic NADPH Oxidase 2

scientific article

Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol

scientific article published on 28 April 2016

Platelet-to-lymphocyte ratio at the time of carotid endarterectomy is associated with acute coronary syndrome occurrence

scientific article published on 20 September 2019

Potential pathophysiological role for the vitamin D deficiency in essential hypertension.

scientific article

Pre-hospital alarm activation for STEMI patients undergoing primary percutaneous coronary intervention in the era of transradial procedures

scientific article published on 16 July 2016

Predictive value of the age, creatinine, and ejection fraction (ACEF) score in patients with acute coronary syndromes

scientific article published in November 2018

Prevalence and management of familial hypercholesterolaemia in patients with acute coronary syndromes

scientific article published on 4 July 2015

Profiling and validation of circulating microRNAs for cardiovascular events in patients presenting with ST-segment elevation myocardial infarction

scientific article published on 23 December 2016

Prognosis of Patients With Familial Hypercholesterolemia After Acute Coronary Syndromes

scientific article published on 26 July 2016

Prognosis of cardiovascular and non-cardiovascular multimorbidity after acute coronary syndrome.

scientific article

Prognostic Value of SYNTAX Score II in Patients with Acute Coronary Syndromes Referred for Invasive Management: A Subanalysis from the SPUM and COMFORTABLE AMI Cohorts

Prognostic value of PCSK9 levels in patients with acute coronary syndromes

scientific article

Quality of care after acute coronary syndromes in a prospective cohort with reasons for non-prescription of recommended medications

scientific article

Reasons for discontinuation of recommended therapies according to the patients after acute coronary syndromes

scientific article

Receptor activator of NF- κB ligand (RANKL) increases the release of neutrophil products associated with coronary vulnerability.

scientific article published on 24 November 2011

Receptor activator of nuclear factor kappa B ligand/osteoprotegerin pathway is a promising target to reduce atherosclerotic plaque calcification

scientific article

Resistin exerts a beneficial role in atherosclerotic plaque inflammation by inhibiting neutrophil migration

scientific article published on 24 July 2018

Role of mitogen-activated protein kinase pathways in multifactorial adverse cardiac remodeling associated with metabolic syndrome

scientific article published on 9 January 2013

Rosuvastatin in older patients with systolic heart failure

scientific article

Safety of Prasugrel Loading Doses in Patients Pre-Loaded With Clopidogrel in the Setting of Primary Percutaneous Coronary Intervention: Results of a Nonrandomized Observational Study

scientific article published in July 2015

Safety profile of prasugrel and clopidogrel in patients with acute coronary syndromes in Switzerland

scientific article

Serum PCSK9 levels predict the occurrence of acute coronary syndromes in patients with severe carotid artery stenosis

scientific article published on 01 July 2018

Serum adiponectin levels predict acute coronary syndrome (ACS) in patients with severe carotid stenosis

scientific article published on 2 January 2018

Serum levels of anti-apolipoprotein A-1 auto-antibodies and myeloperoxidase as predictors of major adverse cardiovascular events after carotid endarterectomy

scholarly article by Giovanni Spinella et al published 2013 in Thrombosis and Haemostasis

Serum levels of osteopontin predict major adverse cardiovascular events in patients with severe carotid artery stenosis

scientific article published on 5 January 2018

Serum lipoprotein (a) predicts acute coronary syndromes in patients with severe carotid stenosis

scientific article

Serum osteopontin levels are upregulated and predict disability after an ischaemic stroke

scientific article published on 24 April 2015

Statin treatment is associated with reduction in serum levels of receptor activator of NF-κB ligand and neutrophil activation in patients with severe carotid stenosis.

scientific article

Systemic and intraplaque mediators of inflammation are increased in patients symptomatic for ischemic stroke

scientific article

The activation of the cannabinoid receptor type 2 reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques.

scientific article

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The liver and the kidney: two critical organs influencing the atherothrombotic risk in metabolic syndrome

The role of adipocytokines in atherogenesis and atheroprogression

scientific article

Thrombus aspiration in acute coronary syndromes: prevalence, procedural success, change in serial troponin T levels and clinical outcomes in a contemporary Swiss cohort

scientific article published in April 2017

Treatment with Angiotensin-(1–7) reduces inflammation in carotid atherosclerotic plaques

scientific article published on 06 February 2014

Treatment with Evasin-3 abrogates neutrophil-mediated inflammation in mouse acute pancreatitis

scientific article

Treatment with Evasin-3 reduces atherosclerotic vulnerability for ischemic stroke, but not brain injury in mice

scientific article published on 19 December 2012

Treatment with KLEPTOSE® CRYSMEB reduces mouse atherogenesis by impacting on lipid profile and Th1 lymphocyte response

scientific article published on 25 April 2015

Treatment with anti-RANKL antibody reduces infarct size and attenuates dysfunction impacting on neutrophil-mediated injury

scientific article published on 4 April 2016

Treatment with recombinant tissue plasminogen activator (r-TPA) induces neutrophil degranulation in vitro via defined pathways

scientific article published on 18 December 2014

Treatment with sulphated galactan inhibits macrophage chemotaxis and reduces intraplaque macrophage content in atherosclerotic mice

scientific article

Treatment with the GPR55 antagonist CID16020046 increases neutrophil activation in mouse atherogenesis.

scientific article published on 28 July 2016

Tumor necrosis factor-alpha (TNF-α) induces integrin CD11b/CD18 (Mac-1) up-regulation and migration to the CC chemokine CCL3 (MIP-1α) on human neutrophils through defined signalling pathways

article

Update on evidence for treatment with ranolazine in stable angina

scientific article

Update on selective treatments targeting neutrophilic inflammation in atherogenesis and atherothrombosis

scientific article published on 28 November 2013

Update on the efficacy of statin treatment in acute coronary syndromes

scientific article

Update on the pathophysiological activities of the cardiac molecule cardiotrophin-1 in obesity

scientific article published on 10 April 2013

Update on the protective molecular pathways improving pancreatic beta-cell dysfunction

scientific article published on 2 May 2013

Update on the role of neutrophils in atherosclerotic plaque vulnerability

scientific article

Vitamin D receptor is expressed within human carotid plaques and correlates with pro-inflammatory M1 macrophages

scientific article published on 20 August 2016

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