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List of works by Qiang Zhang

A bistable switch underlying B-cell differentiation and its disruption by the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin

scientific article

A deterministic map of Waddington's epigenetic landscape for cell fate specification

scientific article

A systems biology perspective on Nrf2-mediated antioxidant response

scientific article

Activation of Nrf2-mediated oxidative stress response in macrophages by hypochlorous acid

scientific article published on 26 September 2007

Adaptive Posttranslational Control in Cellular Stress Response Pathways and Its Relationship to Toxicity Testing and Safety Assessment

scientific article

Adipocyte-specific deficiency of Nfe2l1 disrupts plasticity of white adipose tissues and metabolic homeostasis in mice

scientific article published on 25 June 2018

Adipose deficiency of Nrf2 in ob/ob mice results in severe metabolic syndrome

scientific article published on 13 December 2012

All-or-none suppression of B cell terminal differentiation by environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin

scientific article published on 26 January 2013

An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy

scientific article published on 12 September 2016

Association between arsenic suppression of adipogenesis and induction of CHOP10 via the endoplasmic reticulum stress response

scientific article published on 5 December 2012

Binary gene induction and protein expression in individual cells

scientific article

CNC-bZIP protein Nrf1-dependent regulation of glucose-stimulated insulin secretion

scientific article

Computational systems biology and dose-response modeling in relation to new directions in toxicity testing

scientific article published in February 2010

Cross-regulations among NRFs and KEAP1 and effects of their silencing on arsenic-induced antioxidant response and cytotoxicity in human keratinocytes

scientific article published on 3 January 2012

Deficiency in the nuclear factor E2-related factor 2 renders pancreatic β-cells vulnerable to arsenic-induced cell damage

scientific article

Divergent effects of sulforaphane on basal and glucose-stimulated insulin secretion in β-cells: role of reactive oxygen species and induction of endogenous antioxidants

scientific article published on 07 March 2013

Dose response relationship in anti-stress gene regulatory networks

scientific article

Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages

scientific article published on 17 April 2009

Dose-response modeling of etoposide-induced DNA damage response

scientific article published on 16 November 2013

Embracing Systems Toxicology at Single-Cell Resolution

scientific article published on 19 April 2019

Flutamide Induces Hepatic Cell Death and Mitochondrial Dysfunction via Inhibition of Nrf2-Mediated Heme Oxygenase-1

scientific article published on 02 July 2018

Hepatocyte-specific Nrf2 deficiency mitigates high-fat diet-induced hepatic steatosis: Involvement of reduced PPARγ expression

scientific article published on 23 December 2019

Hormesis and adaptive cellular control systems

scientific article published on 19 March 2008

Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment

scientific article published on 25 February 2014

Iodoacetic Acid Activates Nrf2-Mediated Antioxidant Response in Vitro and in Vivo

article

Isoniazid suppresses antioxidant response element activities and impairs adipogenesis in mouse and human preadipocytes

scientific article published on 12 October 2013

Keap1 silencing boosts lipopolysaccharide-induced transcription of interleukin 6 via activation of nuclear factor κB in macrophages

scientific article published on 29 July 2013

Long isoforms of NRF1 negatively regulate adipogenesis via suppression of PPARγ expression

scientific article published on 28 December 2019

Low-level arsenic impairs glucose-stimulated insulin secretion in pancreatic beta cells: involvement of cellular adaptive response to oxidative stress

scientific article

Mathematical modeling reveals quantitative properties of KEAP1-NRF2 signaling

scientific article published in 2021

Molecular signaling network motifs provide a mechanistic basis for cellular threshold responses

scientific article

Non-monotonic dose-response relationship in steroid hormone receptor-mediated gene expression

scientific article published in May 2007

Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis

scientific article published on 28 October 2011

Phase I to II cross-induction of xenobiotic metabolizing enzymes: a feedforward control mechanism for potential hormetic responses

scientific article

Prolonged inorganic arsenite exposure suppresses insulin-stimulated AKT S473 phosphorylation and glucose uptake in 3T3-L1 adipocytes: involvement of the adaptive antioxidant response

scientific article

ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function

scientific article

Reactive oxygen species as a signal in glucose-stimulated insulin secretion

scientific article

Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small-cell lung carcinoma cells

scientific article

Stochastic modeling of B lymphocyte terminal differentiation and its suppression by dioxin

scientific article

Suppression of NRF2-ARE activity sensitizes chemotherapeutic agent-induced cytotoxicity in human acute monocytic leukemia cells

scientific article published on 18 December 2015

Toxicity testing in the 21 century: defining new risk assessment approaches based on perturbation of intracellular toxicity pathways

scientific article

Ultrasensitive response motifs: basic amplifiers in molecular signalling networks

scientific article

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