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List of works by Toin H van Kuppevelt

'Immunosequencing' of heparan sulfate from human cell lines and rat kidney: the (GlcNS6S-IdoA2S)₃ motif, recognized by antibody NS4F5, is located towards the non-reducing end.

scientific article published on August 2014

A Comparison of Seven Methods to Analyze Heparin in Biomaterials: Quantification, Location, and Anticoagulant Activity

scientific article published on 10 April 2011

A biomaterial composed of collagen and solubilized elastin enhances angiogenesis and elastic fiber formation without calcification

scientific article published in March 2008

A developmentally regulated heparan sulfate epitope defines a subpopulation with increased blood potential during mesodermal differentiation

scientific article published on 11 September 2008

A versatile salt-based method to immobilize glycosaminoglycans and create growth factor gradients

scientific article published on 04 May 2019

Aberrant fibrillin-1 expression in early emphysematous human lung: a proposed predisposition for emphysema.

scientific article published on 14 December 2007

An Animal Model for Femoral Artery Pseudoaneurysms

scientific article published on 10 April 2010

Antibody GD3G7 selected against embryonic glycosaminoglycans defines chondroitin sulfate-E domains highly up-regulated in ovarian cancer and involved in vascular endothelial growth factor binding.

scientific article

Augmented cartilage regeneration by implantation of cellular versus acellular implants after bone marrow stimulation: a systematic review and meta-analysis of animal studies

scientific article published on 27 October 2017

Biodistribution of size-selected lyophilisomes in mice

scientific article published on 5 May 2015

Bladder Regeneration Using Multiple Acellular Scaffolds with Growth Factors in a Bladder

scientific article published on 21 March 2017

Bladder Regeneration Using a Smart Acellular Collagen Scaffold with Growth Factors VEGF, FGF2 and HB-EGF.

scientific article published on 6 October 2015

Changes in the Extracellular Matrix Are Associated With the Development of Serous Tubal Intraepithelial Carcinoma Into High-Grade Serous Carcinoma.

scientific article published on 23 March 2017

Characterization of the heparin/heparan sulfate binding site of the natural cytotoxicity receptor NKp46

scientific article

Characterization of the recognition of tumor cells by the natural cytotoxicity receptor, NKp44.

scientific article

Chemotherapeutic drug delivery by tumoral extracellular matrix targeting.

scientific article

Chondroitin sulfate E fragments enhance CD44 cleavage and CD44-dependent motility in tumor cells

scientific article

Cloning, large-scale production, and purification of active dimeric rat vascular endothelial growth factor (rrVEGF-164).

scientific article

Collagen hydrogels strengthened by biodegradable meshes are a basis for dermo-epidermal skin grafts intended to reconstitute human skin in a one-step surgical intervention.

scientific article

Collagen scaffolds implanted in the palatal mucosa

scientific article published on May 2008

Collagen-Vicryl scaffolds for reconstruction of the diaphragm in a large animal model

scientific article published in May 2014

Construction and evaluation of an antibody phage display library targeting heparan sulfate

scientific article published on 28 May 2020

Construction and in vivo evaluation of a dual layered collagenous scaffold with a radial pore structure for repair of the diaphragm

scientific article published on 14 March 2013

Construction of a Microstructured Collagen Membrane Mimicking the Papillary Dermis Architecture and Guiding Keratinocyte Morphology and Gene Expression

article

Construction of collagen scaffolds that mimic the three-dimensional architecture of specific tissues

scientific article published in October 2007

Cross-linked type I and type II collagenous matrices for the repair of full-thickness articular cartilage defects--a study in rabbits

scientific article published on 01 August 2003

Design of an elasticized collagen scaffold: A method to induce elasticity in a rigid protein

scientific article published on 21 August 2016

Detection of 2-O-sulfated iduronate and N-acetylglucosamine units in heparan sulfate by an antibody selected against acharan sulfate (IdoA2S-GlcNAc)n

scientific article

Differential Expression of Heparan Sulfate Domains in Rat Spleen ⬇️

scientific article published on June 1, 2003

Directing collagen fibers using counter-rotating cone extrusion

scientific article published on 16 October 2014

Drug delivery systems for ovarian cancer treatment: a systematic review and meta-analysis of animal studies.

scientific article

ERRATUM TO: Methods to Study the Role of the Glycocalyx in the Uptake of Cell-Penetrating Peptides

scientific article published on 01 January 2015

Enhanced cellular uptake of albumin-based lyophilisomes when functionalized with cell-penetrating peptide TAT in HeLa cells

scientific article

Essential alterations of heparan sulfate during the differentiation of embryonic stem cells to Sox1-enhanced green fluorescent protein-expressing neural progenitor cells

scientific article published on 26 April 2007

Evaluation of cultured human dermal- and dermo-epidermal substitutes focusing on extracellular matrix components: Comparison of protein and RNA analysis

scientific article published on 29 December 2016

Evaluation of methods for the construction of collagenous scaffolds with a radial pore structure for tissue engineering

scientific article published on 08 February 2011

Extraction and structural analysis of glycosaminoglycans from formalin-fixed, paraffin-embedded tissues

scientific article published on 02 August 2012

FGF-2-loaded collagen scaffolds attract cells and blood vessels in rat oral mucosa

scientific article

Fetal abdominal wall repair with a collagen biomatrix in an experimental sheep model for gastroschisis

scientific article published on 01 December 2008

Fetal bladder wall regeneration with a collagen biomatrix and histological evaluation of bladder exstrophy in a fetal sheep model

scientific article

Fibrillin-1 staining anomalies are associated with increased staining for TGF-beta and elastic fibre degradation; new clues to the pathogenesis of emphysema

scientific article published in August 2009

From molecules to matrix: construction and evaluation of molecularly defined bioscaffolds.

scientific article published on January 2006

Functions of chondroitin sulfate/dermatan sulfate chains in brain development. Critical roles of E and iE disaccharide units recognized by a single chain antibody GD3G7.

scientific article

Heparan sulfate proteoglycans containing a glypican 5 core and 2-O-sulfo-iduronic acid function as Sonic Hedgehog co-receptors to promote proliferation

scientific article published on 18 July 2013

Heparan sulfates in skeletal muscle development and physiology

scientific article

Heparan sulfates in the lung: structure, diversity, and role in pulmonary emphysema

scientific article published on June 2010

Heparinized collagen scaffolds with and without growth factors for the repair of diaphragmatic hernia: construction and in vivo evaluation.

scientific article published on 18 July 2013

Heterogeneity of heparan sulfates in human lung

scientific article

High density gene expression microarrays and gene ontology analysis for identifying processes in implanted tissue engineering constructs

scientific article published on 19 August 2010

Highly sulfated chondroitin sulfates, a novel class of prognostic biomarkers in ovarian cancer tissue

scientific article published on 23 June 2012

Human single-chain antibodies reactive with native chondroitin sulfate detect chondroitin sulfate alterations in melanoma and psoriasis

scientific article published on March 2004

Hypoxia-induced dysfunction of rat diaphragm: role of peroxynitrite.

scientific article published on 10 September 2004

Improved cartilage regeneration by implantation of acellular biomaterials after bone marrow stimulation: a systematic review and meta-analysis of animal studies.

scientific article published on 08 September 2016

Improving the cell distribution in collagen-coated poly-caprolactone knittings

scientific article published on 10 May 2012

In vitro and in vivo effects of deoxyribonucleic acid-based coatings funtionalized with vascular endothelial growth factor

scientific article published on April 2007

Increased angiogenesis and blood vessel maturation in acellular collagen-heparin scaffolds containing both FGF2 and VEGF.

scientific article published on 20 November 2006

Interferon-γ-loaded collagen scaffolds reduce myofibroblast numbers in rat palatal mucosa

scientific article

Intra-uterine tissue engineering of full-thickness skin defects in a fetal sheep model

scientific article

Introduction of Specific 3D Micromorphologies in Collagen Scaffolds Using Odd and Even Dicarboxylic Acids

scientific article published on 18 February 2020

Involvement of chondroitin sulfate E in the liver tumor focal formation of murine osteosarcoma cells

scientific article published on 17 March 2009

Involvement of highly sulfated chondroitin sulfate in the metastasis of the Lewis lung carcinoma cells

scientific article published on 16 October 2008

Is there a need for smooth muscle cell transplantation in urethral reconstruction?

scientific article published on 06 February 2014

Isolation of intact elastin fibers devoid of microfibrils

scientific article

Large, tissue-regulated domain diversity of heparan sulfates demonstrated by phage display antibodies

scientific article published in Journal of Biological Chemistry

Limited independent prognostic value of MMP-14 and MMP-2 expression in ovarian cancer

scientific article published on 2 April 2016

Localization and characterization of melanoma-associated glycosaminoglycans: differential expression of chondroitin and heparan sulfate epitopes in melanoma

scientific article

Lyophilisomes as a new generation of drug delivery capsules.

scientific article

MMP-14 and CD44 in Epithelial-to-Mesenchymal Transition (EMT) in ovarian cancer

scientific article published on 02 September 2016

Methods to Study the Role of the Glycocalyx in the Uptake of Cell-Penetrating Peptides.

scientific article published on January 2015

Micro-computed tomographical imaging of soft biological materials using contrast techniques.

scientific article published in September 2009

Microscale mechanical properties of single elastic fibers: the role of fibrillin-microfibrils

scientific article published on 13 February 2009

Monocyte cell surface glycosaminoglycans positively modulate IL-4-induced differentiation toward dendritic cells

scientific article published in March 2008

Morphological quantification of emphysema in small human lung specimens: comparison of methods and relation with clinical data

scientific article

Muscle fibrosis in the soft palate: Delivery of cells, growth factors and anti-fibrotics

scientific article published on 11 August 2018

Novel single-chain antibody GD3A10 defines a chondroitin sulfate biomarker for ovarian cancer.

scientific article

Novel tubular constructs for urinary diversion: a biocompatibility study in pigs

scientific article

Organ-Specific Tubular and Collagen-Based Composite Scaffolds

scientific article published on 16 January 2011

Phage display-derived human antibodies against specific glycosaminoglycan epitopes

scientific article

Polymorphisms in MMP-14 and MMP-2 genes and ovarian cancer survival

scientific article published on 01 January 2019

Prenatal coverage of experimental gastroschisis with a collagen scaffold to protect the bowel

scientific article published on 01 March 2013

Preparation and characterization of injectable fibrillar type I collagen and evaluation for pseudoaneurysm treatment in a pig model

scientific article published on 3 August 2010

Preparation of differently sized injectable collagen micro-scaffolds

scientific article published on 29 December 2010

Primary Ovarian Tumors With Lymphogenic and Hematogenic Metastasis Express High MMP-14, Which Colocalizes With Highly Sulfated Chondroitin Sulfate in the Stroma

scientific article published on 01 March 2020

Primary ovarian carcinomas and abdominal metastasis contain 4,6-disulfated chondroitin sulfate rich regions, which provide adhesive properties to tumour cells

scientific article

Prognostic significance of highly sulfated chondroitin sulfates in ovarian cancer defined by the single chain antibody GD3A11.

scientific article published on 28 December 2015

Providing direction improves function: Comparison of a radial pore-orientated acellular collagen scaffold to clinical alternatives in a surgically induced rabbit diaphragmatic tissue defect model

scientific article published on 12 September 2018

Regenerative medicine for the respiratory system: distant future or tomorrow's treatment?

scientific article published on 6 December 2012

Repair of surgically created diaphragmatic defect in rat with use of a crosslinked porous collagen scaffold

scientific article published on 15 May 2012

Scaffolds for whole organ tissue engineering: Construction and in vitro evaluation of a seamless, spherical and hollow collagen bladder construct with appendices

scientific article published on 13 July 2016

Seamless vascularized large-diameter tubular collagen scaffolds reinforced with polymer knittings for esophageal regenerative medicine

scientific article published on 28 February 2014

Self-expandable tubular collagen implants

scientific article published on 15 May 2018

Sequencing of glycosaminoglycans with potential to interrogate sequence-specific interactions

scientific article published in November 2017

Similar hyaline-like cartilage repair of osteochondral defects in rabbits using isotropic and anisotropic collagen scaffolds

scientific article published on 19 October 2013

Spatiotemporal distribution of heparan sulfate epitopes during myogenesis and synaptogenesis: a study in developing mouse intercostal muscle

scientific article

Specific targeting of tumor cells by lyophilisomes functionalized with antibodies

scientific article published on 23 January 2014

Sulfated sugars in the extracellular matrix orchestrate ovarian cancer development: 'when sweet turns sour'.

scientific article

Sustained Postnatal Skin Regeneration Upon Prenatal Application of Functionalized Collagen Scaffolds

scientific article published on 22 January 2020

Targeting the extracellular matrix of ovarian cancer using functionalized, drug loaded lyophilisomes.

scientific article published on 26 December 2016

The performance of human dental pulp stem cells on different three-dimensional scaffold materials

scientific article published on 17 August 2006

The polybasic insertion in autotaxin α confers specific binding to heparin and cell surface heparan sulfate proteoglycans

scientific article published on 13 November 2012

The stoichiometry of peptide-heparan sulfate binding as a determinant of uptake efficiency of cell-penetrating peptides

scientific article published on 24 November 2013

Tissue Engineering of Diseased Bladder using a Collagen Scaffold in a Bladder Exstrophy Model

scholarly article by Luc A.J. Roelofs et al published December 2013 in BJU International

Tissue Engineering of the Urethra: A Systematic Review and Meta-analysis of Preclinical and Clinical Studies

scientific article published on 3 April 2017

Tissue engineering of blood vessels: characterization of smooth-muscle cells for culturing on collagen-and-elastin-based scaffolds

scientific article published in April 2004

Tissue engineering of diseased bladder using a collagen scaffold in a bladder exstrophy model

scientific article published on 01 September 2014

Tissue reactions to collagen scaffolds in the oral mucosa and skin of rats: environmental and mechanical factors

scientific article published on 21 February 2008

Tubular collagen scaffolds with radial elasticity for hollow organ regeneration.

scientific article published on 4 February 2017

Unidirectional BMP2-loaded collagen scaffolds induce chondrogenic differentiation

scientific article published on 22 November 2017

Urethral Reconstruction of Critical Defects in Rabbits Using Molecularly Defined Tubular Type I Collagen Biomatrices: Key Issues in Growth Factor Addition

scientific article published on 27 July 2010

Versatile Wedge-Based System for the Construction of Unidirectional Collagen Scaffolds by Directional Freezing: Practical and Theoretical Considerations

scientific article published on 14 April 2015

Visualisation of newly synthesised collagen in vitro and in vivo

scientific article

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