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List of works by Fumiyuki Shirai

Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen

scientific article published on 16 June 2017

Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer

scientific article published on 01 April 2020

Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors

scientific article published on 01 April 2019

Identification of pyrrolo[2,3-d]pyrimidines as potent HCK and FLT3-ITD dual inhibitors

scientific article published on 7 October 2017

Optimization of 2,4-diamino-5-fluoropyrimidine derivatives as protein kinase C theta inhibitors with mitigated time-dependent drug-drug interactions and P-gp liability

scientific article

RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model.

scientific article published on 20 October 2018

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