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List of works by Johan L M Bjorkegren

A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism.

scientific article published in May 2018

A plasma proteogenomic signature for fibromuscular dysplasia

scientific article published on 01 January 2020

ADAMTS-4 and -8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques

scientific article (publication date: February 2008)

Additional Candidate Genes for Human Atherosclerotic Disease Identified Through Annotation Based on Chromatin Organization

scientific article

An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease

scientific article published on 22 January 2021

ApoB100-LDL acts as a metabolic signal from liver to peripheral fat causing inhibition of lipolysis in adipocytes

scientific article

Association analyses based on false discovery rate implicate new loci for coronary artery disease ⬇️

scientific article published on 17 July 2017

Blood levels of dual-specificity phosphatase-1 independently predict risk for post-operative morbidities causing prolonged hospitalization after coronary artery bypass grafting

scientific article published on 17 March 2011

Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity.

scientific article published on 6 September 2017

Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases.

scientific article published on August 2016

Carotid plaque age is a feature of plaque stability inversely related to levels of plasma insulin

scientific article (publication date: 7 April 2011)

Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade

scientific article published on 15 June 2020

Contribution of Gene Regulatory Networks to Heritability of Coronary Artery Disease

scientific article published on 01 June 2019

Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease

scientific article published on 3 March 2016

DGAT1 participates in the effect of HNF4A on hepatic secretion of triglyceride-rich lipoproteins

scientific article published on 18 February 2010

Detecting multivariate differentially expressed genes

scientific article

Detection of compound mode of action by computational integration of whole-genome measurements and genetic perturbations

scientific article

Differences in apolipoprotein and lipid composition between human chylomicron remnants and very low density lipoproteins isolated from fasting and postprandial plasma ⬇️

scientific article published on July 1, 1998

EnsembleCNV: an ensemble machine learning algorithm to identify and genotype copy number variation using SNP array data

scholarly article by Zhongyang Zhang et al published 23 April 2019 in Nucleic Acids Research

Evidence of highly regulated genes (in-Hubs) in gene networks of Saccharomyces cerevisiae

scientific article published on 14 July 2008

Expression quantitative trait Loci acting across multiple tissues are enriched in inherited risk for coronary artery disease

scientific article

Functional and transcriptomic insights into pathogenesis of R9C phospholamban mutation using human induced pluripotent stem cell-derived cardiomyocytes

scientific article published on 09 May 2018

Functional investigation of the coronary artery disease gene SVEP1

scientific article published on 13 November 2020

Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus

scientific article published on 16 November 2018

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

scientific article published in Nature Communications

Genetic regulation of the placental transcriptome underlies birth weight and risk of childhood obesity

scientific article published on 31 December 2018

Global analysis of A-to-I RNA editing reveals association with common disease variants

scientific article published on 6 March 2018

HDL and atherosclerotic cardiovascular disease: genetic insights into complex biology

scientific article published on 10 August 2017

Hormonal regulation of circulating C-reactive protein in men.

scientific article published in May 2005

Human C-reactive protein slows atherosclerosis development in a mouse model with human-like hypercholesterolemia

scholarly article

Human Validation of Genes Associated With a Murine Atherosclerotic Phenotype

scientific article

Human Y Chromosome Exerts Pleiotropic Effects on Susceptibility to Atherosclerosis

scientific article published on 05 September 2019

Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes

scientific article published on 12 March 2021

Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci

scientific article published on 08 July 2016

Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits

scientific article published on 23 August 2019

JCAD Gene at the 10p11 Coronary Artery Disease Locus Regulates Hippo Signaling in Endothelial Cells.

scientific article

Lim domain binding 2: a key driver of transendothelial migration of leukocytes and atherosclerosis

scientific article

Macrophage Trafficking, Inflammatory Resolution, and Genomics in Atherosclerosis: JACC Macrophage in CVD Series (Part 2)

scientific article published on 01 October 2018

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci ⬇️

scientific article

Model-based clustering of multi-tissue gene expression data

scientific article published on 01 March 2020

Multi-organ expression profiling uncovers a gene module in coronary artery disease involving transendothelial migration of leukocytes and LIM domain binding 2: the Stockholm Atherosclerosis Gene Expression (STAGE) study

scientific article

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 12 March 2018

Multiple independent mechanisms link gene polymorphisms in the region of ZEB2 with risk of coronary artery disease

scientific article published on 29 August 2020

Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets

scientific article published on 21 February 2018

Network analysis reveals a causal role of mitochondrial gene activity in atherosclerotic lesion formation

scientific article

On reliable discovery of molecular signatures

scientific article

Opportunities and challenges for transcriptome-wide association studies

scientific article published on 29 March 2019

PanglaoDB: a web server for exploration of mouse and human single-cell RNA sequencing data

research article

Pericyte-specific vascular expression of SARS-CoV-2 receptor ACE2 – implications for microvascular inflammation and hypercoagulopathy in COVID-19 patients

scientific article published on 13 May 2020

Plasma cholesterol-induced lesion networks activated before regression of early, mature, and advanced atherosclerosis

scientific article

Poliovirus Receptor-Related 2: A Cholesterol-Responsive Gene Affecting Atherosclerosis Development by Modulating Leukocyte Migration

scientific article published on 5 January 2017

Postprandial enrichment of remnant lipoproteins with apoC-I in healthy normolipidemic men with early asymptomatic atherosclerosis

scientific article published in September 2002

Prediction of Causal Candidate Genes in Coronary Artery Disease Loci

scientific article

Preservation Analysis of Macrophage Gene Coexpression Between Human and Mouse Identifies PARK2 as a Genetically Controlled Master Regulator of Oxidative Phosphorylation in Humans

scientific article

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 01 July 2019

Publisher Correction: Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination

scientific article published on 03 September 2020

Reverse engineering of gene networks with LASSO and nonlinear basis functions

scientific article published in March 2009

Sex differences in human adipose tissue gene expression and genetic regulation involve adipogenesis

scientific article published on 23 September 2020

Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination

scientific article published on 07 August 2020

Single-cell immune landscape of human atherosclerotic plaques

scientific article published on 07 October 2019

Smoking is Associated to DNA Methylation in Atherosclerotic Carotid Lesions

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease ⬇️

scientific article published on February 2017

Systematic analysis of chromatin interactions at disease associated loci links novel candidate genes to inflammatory bowel disease

scientific article published on 30 November 2016

Systems Pharmacology Identifies an Arterial Wall Regulatory Gene Network Mediating Coronary Artery Disease Side Effects of Antiretroviral Therapy

scientific article published on 06 May 2019

Systems and genome-wide approaches unite to provide a route to personalized medicine

scientific article (publication date: 2012)

Systems biology of innate immunity

scientific article

The Low Density Lipoprotein Receptor Prevents Secretion of Dense ApoB100-containing Lipoproteins from the Liver ⬇️

scientific article published on October 28, 2003

The State of Systems Genetics in 2017.

scientific article

The Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis

scientific article published on 17 July 2020

The apolipoprotein CI content of triglyceride-rich lipoproteins independently predicts early atherosclerosis in healthy middle-aged men.

scientific article

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line.

scientific article

Thematic review series: systems biology approaches to metabolic and cardiovascular disorders. Multi-organ whole-genome measurements and reverse engineering to uncover gene networks underlying complex traits

scientific article published on December 2006

Transcription Regulatory Networks Analysis Using CAGE

Transcriptional network dynamics in macrophage activation

scientific article published on 12 May 2006

Transcriptional profiling uncovers a network of cholesterol-responsive atherosclerosis target genes

scientific article

Transcriptome-wide association studies: opportunities and challenges

Transient triglyceridemia in healthy normolipidemic men increases cellular processing of large very low density lipoproteins by fibroblasts in vitro ⬇️

scientific article published on February 1, 1998

Variants in ALOX5, ALOX5AP and LTA4H are not associated with atherosclerotic plaque phenotypes: the Athero-Express Genomics Study

scientific article published on 20 January 2015

alona: a web server for single cell RNA-seq analysis

scientific article published on 23 April 2020

kruX: matrix-based non-parametric eQTL discovery

scientific article published on 14 January 2014

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