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List of works by Saadia A Karim

CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma

scientific article

CXCR2 inhibition suppresses acute and chronic pancreatic inflammation

scientific article published on 4 June 2015

Dasatinib inhibits mammary tumour development in a genetically engineered mouse model

scientific article published on August 2013

Dasatinib inhibits the development of metastases in a mouse model of pancreatic ductal adenocarcinoma

scientific article published on 17 March 2010

FLIM-FRET imaging in vivo reveals 3D-environment spatially regulates RhoGTPase activity during cancer cell invasion

scientific article

Genomic instability in mutant p53 cancer cells upon entotic engulfment

scientific article published in Nature Communications

Intravital FLIM-FRET imaging reveals dasatinib-induced spatial control of src in pancreatic cancer

scientific article published on 7 June 2013

Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue

scientific article published on 22 December 2015

LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest

scientific article published on 06 May 2010

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

scientific article

Publisher Correction: Genomic instability in mutant p53 cancer cells upon entotic engulfment

scientific article published in Nature Communications

Repression of the Type I Interferon pathway underlies MYC & KRAS-dependent evasion of NK & B cells in Pancreatic Ductal Adenocarcinoma

scientific article published on 21 March 2020

Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53

scientific article

Targeting mTOR dependency in pancreatic cancer

scientific article

Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy.

scientific article published on 15 June 2015

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