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List of works by Peter L Turecek

A Flow-Cytometry-Based Approach to Facilitate Quantification, Size Estimation and Characterization of Sub-visible Particles in Protein Solutions

scientific article published on 19 March 2015

A bio-inspired method for direct measurement of local wall shear rates with micrometer localization using the multimeric protein von Willebrand factor as sensor molecule.

scientific article published in July 2017

A comparison of nano-electrospray gas-phase electrophoretic mobility macromolecular analysis and matrix-assisted laser desorption/ionization linear time-of-flight mass spectrometry for the characterization of the recombinant coagulation glycoprotein

scientific article

A fully recombinant partial prothrombin complex effectively bypasses fVIII in vitro and in vivo.

scientific article published in December 2002

ADAMTS13 autoantibody detection by quantitative immunoblotting

scientific article published on 01 September 2003

Activation and inactivation of human factor X by proteases derived from Ficus carica

scientific article published on 01 December 2002

Anti-ADAMTS13 IgG autoantibodies present in healthy individuals share linear epitopes with those in patients with thrombotic thrombocytopenic purpura.

scientific article published on 14 February 2014

Biochemical, molecular characterization, and glycoproteomic analyses of alpha(1)-proteinase inhibitor products used for replacement therapy.

scientific article

Biological mechanisms underlying inter-individual variation in factor VIII clearance in haemophilia

scientific article published on 28 June 2020

Ca(2+) concentration-dependent conformational change of FVIII B-domain observed by atomic force microscopy

scientific article published on 23 May 2015

Changes in ADAMTS13 (von-Willebrand-factor-cleaving protease) activity after induced release of von Willebrand factor during acute systemic inflammation

scientific article published on 01 March 2005

Changes in von Willebrand factor-cleaving protease (ADAMTS13) activity after infusion of desmopressin

scientific article published on 19 September 2002

Comparative study on collagen-binding enzyme-linked immunosorbent assay and ristocetin cofactor activity assays for detection of functional activity of von Willebrand factor

scientific article

Comparison of plasma-derived and recombinant von Willebrand factor by atomic force microscopy

scientific article published on 29 June 2010

Comprehensive glyco-proteomic analysis of human alpha1-antitrypsin and its charge isoforms

scientific article published in June 2006

Convenient high-resolution isoelectric focusing (IEF) method for the separation of alpha1-proteinase inhibitor (A1PI) isoforms in A1PI concentrates

scientific article published on 13 June 2007

Development of a lectin binding assay to differentiate between recombinant and endogenous proteins in pharmacokinetic studies of protein-biopharmaceuticals

scientific article published on 2 February 2015

Development, Validation, and Application of a Novel Ligand-Binding Assay to Selectively Measure PEGylated Recombinant Human Coagulation Factor VIII (BAX 855).

scientific article published on 3 September 2015

Ethanol dependence of alpha 1-antitrypsin C-terminal Lys truncation mediated by basic carboxypeptidases

scientific article published on 19 November 2007

Evaluation of Factor VIII Polysialylation: Identification of a Longer-Acting Experimental Therapy in Mice and Monkeys

scientific article published on 31 July 2019

Evaluation of the haemostatic potential of factor VIII‐heparin cofactor II hybrid proteins in a mouse model ⬇️

scientific article published on November 1, 2003

Evolution of replacement therapy for von Willebrand disease: From plasma fraction to recombinant von Willebrand factor

scientific article published on 03 April 2019

GEMMA and MALDI-TOF MS of reactive PEGs for pharmaceutical applications

scientific article

High prevalence of elevated clotting factor VIII in chronic thromboembolic pulmonary hypertension

scientific article published on 01 September 2003

High-dose factor VIII inhibits factor VIII-specific memory B cells in hemophilia A with factor VIII inhibitors

scientific article published on 9 August 2005

In vitro and in vivo anti-retroviral activity of the substance purified from the aqueous extract of Chelidonium majus L.

scientific article published on 18 April 2006

In vivo and in vitro processing of recombinant pro-von Willebrand factor

scientific article

Issues complicating precision dosing for factor VIII prophylaxis

scientific article published on 21 August 2018

Long-term persistence of anti-factor VIII antibody-secreting cells in hemophilic mice after treatment with human factor VIII

scientific article published on 01 May 2002

Low ADAMTS13 activity is associated with an increased risk of ischemic stroke.

scientific article

MALDI linear TOF mass spectrometry of PEGylated (glyco)proteins

scientific article

Maintenance and break of immune tolerance against human factor VIII in a new transgenic hemophilic mouse model

scientific article published on 24 June 2011

Microchip capillary gel electrophoresis of multiply PEGylated high-molecular-mass glycoproteins

scientific article published in May 2012

Mutation of the surface-exposed amino acid Trp to Ala in the FVIII C2 domain results in defective secretion of the otherwise functional protein

scientific article published on June 2004

Nonacog gamma, a novel recombinant factor IX with low factor IXa content for treatment and prophylaxis of bleeding episodes

scientific article

Origins, Development, Current Challenges and Future Directions with Activated Prothrombin Complex Concentrate for the Treatment of Patients with Congenital Haemophilia with Inhibitors

scientific article published on 27 July 2020

PEGylated Biopharmaceuticals: Current Experience and Considerations for Nonclinical Development

scientific article

PEGylation of Biopharmaceuticals: A Review of Chemistry and Nonclinical Safety Information of Approved Drugs

scientific article published on February 2016

Persistence of circulating ADAMTS13-specific immune complexes in patients with acquired thrombotic thrombocytopenic purpura

scientific article

Pharmacokinetics and safety of a novel recombinant human von Willebrand factor manufactured with a plasma-free method: a prospective clinical trial ⬇️

scientific article published on June 18, 2013

Polyethylene Glycol Exposure with Antihemophilic Factor (Recombinant), PEGylated (rurioctocog alfa pegol) and Other Therapies Indicated for the Pediatric Population: History and Safety

scientific article published on 26 July 2018

Polysialic Acid-Mediated Activity Measurement of Polysialylated Recombinant Coagulation Factor VIII

scientific article published on 16 October 2019

Preclinical safety and efficacy of a new recombinant FIX drug product for treatment of hemophilia B.

scientific article published on 24 September 2013

Preclinical testing of human recombinant von Willebrand factor: ADAMTS13 cleavage capacity in animals as criterion for species suitability

scientific article published on 14 July 2010

Preventing restimulation of memory B cells in hemophilia A: a potential new strategy for the treatment of antibody-dependent immune disorders

scientific article published on 4 March 2004

Proteomic analysis of UVC irradiation-induced damage of plasma proteins: Serum amyloid P component as a major target of photolysis

scientific article published on 06 May 2006

Recombinant factor VIII and factor VIII-von Willebrand factor complex do not present danger signals for human dendritic cells

scientific article published in September 2006

Recombinant von Willebrand factor-insight into structure and function through infusion studies in animals with severe von Willebrand disease

scientific article published on 01 April 2002

Selective functional activity measurement of a PEGylated protein with a modification-dependent activity assay

scientific article

Sensitive and specific assessment of recombinant von Willebrand factor in platelet function analyzer

scientific article

Shear-Dependent Interactions of von Willebrand Factor with Factor VIII and Protease ADAMTS 13 Demonstrated at a Single Molecule Level by Atomic Force Microscopy

scientific article published on 14 September 2015

Single cell analysis of factor VIII-specific T cells in hemophilic mice after treatment with human factor VIII

scientific article published on 01 February 2002

Structural analysis of the recombinant therapeutic product rFVIII and its PEGylated variants using 2‐D DIGE ⬇️

scientific article published on April 26, 2011

Structure and function of a recombinant von Willebrand factor drug candidate

scientific article published on 15 July 2010

Successful treatment of patients with von Willebrand disease using a high-purity double-virus inactivated factor VIII/von Willebrand factor concentrate (Immunate).

scientific article

The 1st International Standard for von Willebrand Factor concentrate: more to come?

scientific article published on 01 September 2002

The role of ultralarge multimers in recombinant human von Willebrand factor - a review of physico-and biochemical studies and findings in in vivo models and in humans with von Willebrand disease

scientific article published on 28 December 2017

Update on the mechanism of action and future of activated prothrombin complex concentrates.

scientific article published in September 2004

Visualization of a protein-protein interaction at a single-molecule level by atomic force microscopy.

scientific article

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