List of works - Vicente Planelles

A Conserved HIV-1-Derived Peptide Presented by HLA-E Renders Infected T-cells Highly Susceptible to Attack by NKG2A/CD94-Bearing Natural Killer Cells.

scientific article published in February 2016

Activation of the ATR pathway by human immunodeficiency virus type 1 Vpr involves its direct binding to chromatin in vivo

scientific article

Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy

scientific article

An HIV-encoded antisense long noncoding RNA epigenetically regulates viral transcription

scientific article

An Ounce of Tat Prevention Is Worth a Pound of Functional Cure

scientific article

An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients

scientific article (publication date: 2013)

BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency.

scientific article

Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation.

scientific article published in January 2017

CD155 on HIV-Infected Cells Is Not Modulated by HIV-1 Vpu and Nef but Synergizes with NKG2D Ligands to Trigger NK Cell Lysis of Autologous Primary HIV-Infected Cells

scientific article published on 13 June 2016

Characterization of the molecular determinants of primary HIV-1 Vpr proteins: impact of the Q65R and R77Q substitutions on Vpr functions

scientific article

Characterizing the anti-HIV activity of papuamide A

scientific article

Current status of gene therapy strategies to treat HIV/AIDS.

scientific article

Degranulation of Natural Killer Cells Following Interaction with HIV-1-Infected Cells Is Hindered by Downmodulation of NTB-A by Vpu ⬇️

scientific article published on November 18, 2010

Determinants for degradation of SAMHD1, Mus81 and induction of G2 arrest in HIV-1 Vpr and SIVagm Vpr.

scientific article published on 22 January 2015

Differential effects of Vpr on single-cycle and spreading HIV-1 infections in CD4+ T-cells and dendritic cells

scientific article

Downmodulation of CCR7 by HIV-1 Vpu results in impaired migration and chemotactic signaling within CD4⁺ T cells

scientific article published on 5 June 2014

Endostatin gene transfer inhibits joint angiogenesis and pannus formation in inflammatory arthritis

scientific article

Epigenetic regulation of HIV-1 latency by cytosine methylation

scientific article

Evaluation of a multiple-cycle, recombinant virus, growth competition assay that uses flow cytometry to measure replication efficiency of human immunodeficiency virus type 1 in cell culture

scientific article

Ex Vivo Bioactivity and HIV-1 Latency Reversal by Ingenol Dibenzoate and Panobinostat in Resting CD4(+) T Cells from Aviremic Patients

scientific article

HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay

scientific article

HIV-1 Vpr inhibits cytokinesis in human proximal tubule cells

scientific article

HIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage response

scientific article published on 2 October 2009

HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT

scientific article

HIV-1 Vpr: mechanisms of G2 arrest and apoptosis

scientific article published on 25 April 2008

HIV-1 Vpu utilizes both cullin-RING ligase (CRL) dependent and independent mechanisms to downmodulate host proteins

scientific article published on 28 July 2015

HIV-1-based defective lentiviral vectors efficiently transduce human monocytes-derived macrophages and suppress replication of wild-type HIV-1

scientific article

Homeostatic proliferation fails to efficiently reactivate HIV-1 latently infected central memory CD4+ T cells

scientific article

Host factors influencing susceptibility to HIV infection and AIDS progression

scientific article

Human immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation

scientific article published on 12 September 2007

Induction of G2 arrest and binding to cyclophilin A are independent phenotypes of human immunodeficiency virus type 1 Vpr

scientific article

Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells

scientific article published on 10 October 2008

Induction of cell cycle arrest by human T-cell lymphotropic virus type 1 Tax in hematopoietic progenitor (CD34+) cells: modulation of p21cip1/waf1 and p27kip1 expression

scientific article

Janus kinase inhibition suppresses PKC-induced cytokine release without affecting HIV-1 latency reversal ex vivo

scientific article published on 20 December 2016

Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase

scientific article

Modeling HIV-1 Latency in Primary T Cells Using a Replication-Competent Virus.

scientific article published on 14 July 2015

Neutralization Assay with SARS-CoV-1 and SARS-CoV-2 Spike Pseudotyped Murine Leukemia Virions

scientific article published on 21 September 2020

Reactivation of latent HIV-1 in central memory CD4⁺ T cells through TLR-1/2 stimulation

scientific article published on 24 October 2013

Recommendations for measuring HIV reservoir size in cure-directed clinical trials

scientific article published on 07 September 2020

Replication competent virus as an important source of bias in HIV latency models utilizing single round viral constructs

scientific article

Ruxolitinib and tofacitinib are potent and selective inhibitors of HIV-1 replication and virus reactivation in vitro.

scientific article

Stable integrant-specific differences in bimodal HIV-1 expression patterns revealed by high-throughput analysis

scientific article published on 04 October 2019

Sulfonation pathway inhibitors block reactivation of latent HIV-1.

scientific article

The ataxia telangiectasia-mutated and Rad3-related protein is dispensable for retroviral integration

scientific article

The role of Vpr in HIV-1 pathogenesis

scientific article

Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model.

scientific article

Understanding the molecular manipulation of DCAF1 by the lentiviral accessory proteins Vpr and Vpx.

scientific article

Vectors derived from the human immunodeficiency virus HIV-1

scientific article published on May 1, 2003

List of works by Vicente Planelles

A Conserved HIV-1-Derived Peptide Presented by HLA-E Renders Infected T-cells Highly Susceptible to Attack by NKG2A/CD94-Bearing Natural Killer Cells.

Activation of the ATR pathway by human immunodeficiency virus type 1 Vpr involves its direct binding to chromatin in vivo

Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy

An HIV-encoded antisense long noncoding RNA epigenetically regulates viral transcription

An Ounce of Tat Prevention Is Worth a Pound of Functional Cure

An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients

BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency.

Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation.

CD155 on HIV-Infected Cells Is Not Modulated by HIV-1 Vpu and Nef but Synergizes with NKG2D Ligands to Trigger NK Cell Lysis of Autologous Primary HIV-Infected Cells

Characterization of the molecular determinants of primary HIV-1 Vpr proteins: impact of the Q65R and R77Q substitutions on Vpr functions

Characterizing the anti-HIV activity of papuamide A

Current status of gene therapy strategies to treat HIV/AIDS.

Degranulation of Natural Killer Cells Following Interaction with HIV-1-Infected Cells Is Hindered by Downmodulation of NTB-A by Vpu ⬇️

Determinants for degradation of SAMHD1, Mus81 and induction of G2 arrest in HIV-1 Vpr and SIVagm Vpr.

Differential effects of Vpr on single-cycle and spreading HIV-1 infections in CD4+ T-cells and dendritic cells

Downmodulation of CCR7 by HIV-1 Vpu results in impaired migration and chemotactic signaling within CD4⁺ T cells

Endostatin gene transfer inhibits joint angiogenesis and pannus formation in inflammatory arthritis

Epigenetic regulation of HIV-1 latency by cytosine methylation

Evaluation of a multiple-cycle, recombinant virus, growth competition assay that uses flow cytometry to measure replication efficiency of human immunodeficiency virus type 1 in cell culture

Ex Vivo Bioactivity and HIV-1 Latency Reversal by Ingenol Dibenzoate and Panobinostat in Resting CD4(+) T Cells from Aviremic Patients

HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay

HIV-1 Vpr inhibits cytokinesis in human proximal tubule cells

HIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage response

HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT

HIV-1 Vpr: mechanisms of G2 arrest and apoptosis

HIV-1 Vpu utilizes both cullin-RING ligase (CRL) dependent and independent mechanisms to downmodulate host proteins

HIV-1-based defective lentiviral vectors efficiently transduce human monocytes-derived macrophages and suppress replication of wild-type HIV-1

Homeostatic proliferation fails to efficiently reactivate HIV-1 latently infected central memory CD4+ T cells

Host factors influencing susceptibility to HIV infection and AIDS progression

Human immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation

Induction of G2 arrest and binding to cyclophilin A are independent phenotypes of human immunodeficiency virus type 1 Vpr

Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells

Induction of cell cycle arrest by human T-cell lymphotropic virus type 1 Tax in hematopoietic progenitor (CD34+) cells: modulation of p21cip1/waf1 and p27kip1 expression

Janus kinase inhibition suppresses PKC-induced cytokine release without affecting HIV-1 latency reversal ex vivo

Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase

Modeling HIV-1 Latency in Primary T Cells Using a Replication-Competent Virus.

Neutralization Assay with SARS-CoV-1 and SARS-CoV-2 Spike Pseudotyped Murine Leukemia Virions

Reactivation of latent HIV-1 in central memory CD4⁺ T cells through TLR-1/2 stimulation

Recommendations for measuring HIV reservoir size in cure-directed clinical trials

Replication competent virus as an important source of bias in HIV latency models utilizing single round viral constructs

Ruxolitinib and tofacitinib are potent and selective inhibitors of HIV-1 replication and virus reactivation in vitro.

Stable integrant-specific differences in bimodal HIV-1 expression patterns revealed by high-throughput analysis

Sulfonation pathway inhibitors block reactivation of latent HIV-1.

The ataxia telangiectasia-mutated and Rad3-related protein is dispensable for retroviral integration

The role of Vpr in HIV-1 pathogenesis

Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model.

Understanding the molecular manipulation of DCAF1 by the lentiviral accessory proteins Vpr and Vpx.

Vectors derived from the human immunodeficiency virus HIV-1