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List of works by Kyu-Yup Lee

A Case of Cochlear Implantation in a Postligual Deaf Patient with Osteogenesis Imperfecta

scientific article published in 2009

A Case of Pulsatile Tinnitus Related to Idiopathic Intracranial Hypertension

scientific article published in 2020

A Case of Sensorineural Hearing Loss Caused by Neurosyphilis in Patient Who Is Treated by Anti-Interleukin 17A Monoclonal Antibody

scientific article published in 2022

A Family of H723R Mutation for SLC26A4 Associated with Enlarged Vestibular Aqueduct Syndrome

scientific article published on 29 June 2009

A Noncoding Point Mutation of Zeb1 Causes Multiple Developmental Malformations and Obesity in Twirler Mice ⬇️

scientific article published on September 29, 2011

A Novel Frameshift Mutation of SLC26A4 in a Korean Family With Nonsyndromic Hearing Loss and Enlarged Vestibular Aqueduct

scientific article published on 07 July 2016

A missense variant of the ATP1A2 gene is associated with a novel phenotype of progressive sensorineural hearing loss associated with migraine

scientific article

A novel COCH mutation associated with autosomal dominant nonsyndromic hearing loss disrupts the structural stability of the vWFA2 domain

scientific article

A novel frameshift mutation of POU4F3 gene associated with autosomal dominant non-syndromic hearing loss

scientific article published on 29 April 2010

A novel insertion-induced frameshift mutation of the SLC26A4 gene in a Korean family with Pendred syndrome ⬇️

scientific article published on August 4, 2012

A novel missense variant in the DIAPH1 gene in a Korean family with autosomal dominant nonsyndromic hearing loss

scientific article published on 21 December 2016

A rapid method for simultaneous screening of multi-gene mutations associated with hearing loss in the Korean population

scientific article

A1555G homoplasmic mutation from A1555G heteroplasmic mother with Pendred syndrome

scientific article published on 17 August 2014

Alpha-lipoic acid protects against cisplatin-induced ototoxicity via the regulation of MAPKs and proinflammatory cytokines

scientific article published on 2 May 2014

Application of allele-specific primer extension-based microarray for simultaneous multi-gene mutation screening in patients with non-syndromic hearing loss

scientific article published in March 2010

Association Between HbA1c Level and Hearing Impairment in a Nondiabetic Adult Population

scientific article published on 7 January 2016

Association Between Hearing Impairment and Albuminuria With or Without Diabetes Mellitus

scientific article published on 23 December 2016

Association between a High-Potassium Diet and Hearing Thresholds in the Korean Adult Population

scientific article published on 04 July 2019

Association of Bone Mineral Density With Hearing Impairment in Postmenopausal Women in Korea

scientific article published on 02 May 2016

CRISPR/Cas9-mediated genome editing of splicing mutation causing congenital hearing loss

scientific article published on 18 March 2019

Clinical Aspects and Surgical Outcomes of Congenital Cholesteatoma in 93 Children: Increasing Trends of Congenital Cholesteatoma from 1997 through 2012.

scientific article

Clinical and molecular characterizations of novel POU3F4 mutations reveal that DFN3 is due to null function of POU3F4 protein.

scientific article

Clinical outcomes of otogenic skull base osteomyelitis

scientific article published on 22 September 2020

Cochlear Implant in Patients with Incomplete Partition Type III

scientific article published in 2009

Comparison among Three Different Steroid Therapies for Idiopathic Sudden Sensorineural Hearing Loss

scientific article published in 2020

Comparison of Various Anthropometric Indices as Risk Factors for Hearing Impairment in Asian Women

scientific article published on 17 November 2015

Comparison of auditory responses determined by acoustic stimulation and by mechanical round window stimulation at equivalent stapes velocities

scientific article published on 24 April 2014

Conductive hearing loss with an intact tympanic membrane due to non-inflammatory causes

scientific article published on 8 July 2015

Correction to: Exocyst Complex Member EXOC5 Is Required for Survival of Hair Cells and Spiral Ganglion Neurons and Maintenance of Hearing

scientific article published on 01 March 2019

Dexamethasone Is One of the Factors Minimizing the Inner Ear Damage from Electrode Insertion in Cochlear Implantation

scientific article published on 28 May 2016

Different functional consequences of two missense mutations in the GJB2 gene associated with non-syndromic hearing loss.

scientific article published in July 2009

Effect of bimodal hearing in Korean children with profound hearing loss

scientific article published in November 2008

Effect of prehydration solution on hearing threshold after chemotherapy in patients with head and neck cancers: a retrospective study

scientific article published in 2022

Effective PEI-mediated delivery of CRISPR-Cas9 complex for targeted gene therapy

scientific article published on 30 June 2018

Evaluating protective and therapeutic effects of alpha-lipoic acid on cisplatin-induced ototoxicity

scientific article published on 01 August 2018

Evaluation of the contribution of the EYA4 and GRHL2 genes in Korean patients with autosomal dominant non-syndromic hearing loss

scientific article

Evaluation of the pathogenicity of GJB3 and GJB6 variants associated with nonsyndromic hearing loss ⬇️

scientific article published on May 19, 2012

Evaluation of white matter structures in patients with tinnitus using diffusion tensor imaging

scientific article published on 23 March 2007

Exocyst Complex Member EXOC5 Is Required for Survival of Hair Cells and Spiral Ganglion Neurons and Maintenance of Hearing.

scientific article

Functional activity mapping of rat auditory pathway after intratympanic manganese administration

scientific article published on 17 January 2012

Functional evaluation of GJB2 variants in nonsyndromic hearing loss.

scientific article

Functional mapping of the auditory tract in rodent tinnitus model using manganese-enhanced magnetic resonance imaging

scientific article published on 28 June 2014

Fursultiamine Prevents Drug-Induced Ototoxicity by Reducing Accumulation of Reactive Oxygen Species in Mouse Cochlea

scientific article published in 2021

Galangin prevents aminoglycoside-induced ototoxicity by decreasing mitochondrial production of reactive oxygen species in mouse cochlear cultures

scientific article

Gene therapy for hereditary hearing loss by SLC26A4 mutations in mice reveals distinct functional roles of pendrin in normal hearing

scientific article published on 23 September 2019

Genetic analysis of COL11A2 in Korean patients with autosomal dominant non-syndromic hearing loss

Genetic analysis of TMPRSS3 gene in the Korean population with autosomal recessive nonsyndromic hearing loss

scientific article

Genetic analysis of auditory neuropathy spectrum disorder in the Korean population

scientific article published on 4 April 2013

Genetic analysis of genes related to tight junction function in the Korean population with non-syndromic hearing loss

scientific article

Genetic association of MYH genes with hereditary hearing loss in Korea

scientific article published on 5 July 2016

Identification and functional characterization of novel compound heterozygotic mutations in the TECTA gene ⬇️

scientific article published on October 20, 2011

Identification of a nonsense mutation in the STRC gene in a Korean family with moderate hearing loss

scientific article published on 23 November 2015

Identification of a novel nonsynonymous mutation of EYA1 disrupting splice site in a Korean patient with BOR syndrome

scientific article published on 4 March 2014

Identification of a novel splicing mutation within SLC17A8 in a Korean family with hearing loss by whole-exome sequencing.

scientific article

Identification of causative mutation in a Korean family with Crouzon syndrome using whole exome sequencing

scientific article

Identification of pathogenic mechanisms of COCH mutations, abolished cochlin secretion, and intracellular aggregate formation: genotype-phenotype correlations in DFNA9 deafness and vestibular disorder

scientific article

Intratympanic manganese administration revealed sound intensity and frequency dependent functional activity in rat auditory pathway

scientific article published on 6 May 2013

Is Body Mass Index Associated With the Development of Age-Related Hearing Impairment in Koreans? The Korean National Health and Nutrition Examination Survey 2009-2012.

scientific article published on 19 April 2016

KL1333, a derivative of β-lapachone, protects against cisplatin-induced ototoxicity in mouse cochlear cultures

scientific article published on 20 March 2020

Language Development in Profoundly Prelingually Deaf Children with Cochlear Implantation: Long-Term Outcomes

scientific article published in 2016

Mechanism of Tinnitus Generation

scientific article published in 2014

Methionine Sulfoxide Reductase B3-Targeted In Utero Gene Therapy Rescues Hearing Function in a Mouse Model of Congenital Sensorineural Hearing Loss.

scientific article

Methionine sulfoxide reductase A, B1 and B2 are likely to be involved in the protection against oxidative stress in the inner ear.

scientific article published on 13 December 2014

Methionine sulfoxide reductase B3 deficiency causes hearing loss due to stereocilia degeneration and apoptotic cell death in cochlear hair cells.

scientific article published on 3 November 2013

Mitochondrial redox system: A key target of antioxidant therapy to prevent acquired sensorineural hearing loss

scientific article published in 2023

Modified U1 snRNA and antisense oligonucleotides rescue splice mutations in SLC26A4 that cause hereditary hearing loss

scientific article published on 21 May 2019

Molecular analysis of mitochondrial gene mutations in Korean patients with nonsyndromic hearing loss.

scientific article

Molecular and Clinical Characterization of the Variable Phenotype in Korean Families with Hearing Loss Associated with the Mitochondrial A1555G Mutation ⬇️

scientific article published on August 6, 2012

Molecular cloning, characterization, and expression of pannexin genes in chicken

scientific article

Mouse model of enlarged vestibular aqueducts defines temporal requirement of Slc26a4 expression for hearing acquisition

scientific article

Nonsyndromic X-linked hearing loss

scientific article published on January 2012

Novel EYA1 mutation in a Korean branchio-oto-renal syndrome family

scientific article published on 17 October 2006

Novel therapy for hearing loss: delivery of insulin-like growth factor 1 to the cochlea using gelatin hydrogel

scientific article published in October 2007

Pannexin 3 is required for normal progression of skeletal development in vertebrates

scientific article published on 16 July 2015

Pathogenic effects of a novel mutation (c.664_681del) in KCNQ4 channels associated with auditory pathology ⬇️

scientific article published on September 9, 2010

Prediction of Cochlear Implant Outcomes in Patients With Prelingual Deafness

scientific article published on 25 June 2016

Prediction of hearing outcomes in chronic otitis media patients underwent tympanoplasty using ossiculoplasty outcome parameter staging or middle ear risk indices

scientific article published in 2021

Protective effects of 1,2,3-triazole derivative KPR-A020 against cisplatin-induced ototoxicity in murine cochlear cultures

scientific article

Red cell distribution width is associated with hearing impairment in chronic kidney disease population: a retrospective cross-sectional study

scientific article published on 19 March 2020

Results of Active Middle Ear Implantation in Patients With Mixed Hearing Loss After Middle Ear Surgery: A Prospective Multicenter Study (the ROMEO Study)

scientific article published in 2022

Revealing the function of a novel splice-site mutation of CHD7 in CHARGE syndrome

scientific article published on 6 November 2015

Reversible Sensorineural Hearing Loss due to Pachymeningitis Associated with Elevated Serum MPO-ANCA ⬇️

scientific article published on February 7, 2011

SLC26A4 mutation testing for hearing loss associated with enlargement of the vestibular aqueduct

scientific article published on May 2013

Screening of the SLC17A8 gene as a causative factor for autosomal dominant non-syndromic hearing loss in Koreans

scientific article published on 22 January 2016

Sound Processor Replacement in Patients with Cochlear Implant: Analysis of a 30-Year Single-Institutional Experience

scientific article published in 2021

Surgical invasiveness of cell transplantation into the guinea pig cochlear modiolus

scientific article published on 30 October 2008

Surgical outcomes of early congenital cholesteatoma: minimally invasive transcanal approach

scientific article published on 19 September 2013

Targeted massive parallel sequencing: the effective detection of novel causative mutations associated with hearing loss in small families ⬇️

scientific article published on September 3, 2012

The Influence of Education Level on Tinnitus and Quality of Life in Korean Adults

scientific article published in 2019

The effect of novel mutations on the structure and enzymatic activity of unconventional myosins associated with autosomal dominant non-syndromic hearing loss.

scientific article

The efficacy of combination therapy for idiopathic sudden sensorineural hearing loss

scientific article published on 12 March 2016

The pathological effects of connexin 26 variants related to hearing loss by in silico and in vitro analysis

scientific article published on 9 January 2016

Therapeutic potential of the mitochondria-targeted antioxidant MitoQ in mitochondrial-ROS induced sensorineural hearing loss caused by Idh2 deficiency

scientific article published on 20 November 2018

Two novel missense mutations in the TECTA gene in Korean families with autosomal dominant nonsyndromic hearing loss ⬇️

scientific article published on January 1, 2010

Visceral Fat Area Determined Using Bioimpedance Analysis Is Associated with Hearing Loss

scientific article

Voxel-wise analysis of diffusion tensor imaging for clinical outcome of cochlear implantation: retrospective study

scientific article

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