List of works - Oscar L Lopez

18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

scientific article published in February 2018

3D mapping of ventricular and corpus callosum abnormalities in HIV/AIDS.

scientific article published on 19 January 2006

3D pattern of brain atrophy in HIV/AIDS visualized using tensor-based morphometry

scientific article

A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly

scientific article

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

scientific article published on 02 August 2019

Association of Alzheimer's disease GWAS loci with MRI markers of brain aging

scientific article

Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals

scientific article

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans

scientific article published on 16 February 2012

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

scientific article published on 01 May 2019

Brain structure and obesity

scientific article

Cerebral small vessel disease genomics and its implications across the lifespan

scientific article published on 08 December 2020

Cerebral ventricular changes associated with transitions between normal cognitive function, mild cognitive impairment, and dementia

scientific article

Common folate gene variant, MTHFR C677T, is associated with brain structure in two independent cohorts of people with mild cognitive impairment

scientific article published on 04 October 2012

Common variants at 12q14 and 12q24 are associated with hippocampal volume

scientific article

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

scientific article (publication date: May 2011)

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

scientific article

Correction: Genetic data and cognitively defined late-onset Alzheimer's disease subgroups

scientific article published on 15 January 2019

Developing a national strategy to prevent dementia: Leon Thal Symposium 2009.

scientific article

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

scientific article

Estrogen, brain structure, and cognition in postmenopausal women

scientific article published on 10 September 2020

Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease

scientific article published on 18 June 2016

Fast 3D Fluid Registration of Brain Magnetic Resonance Images.

scientific article

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

scientific article

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

scholarly article published 28 August 2017

Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium

article published in 2018

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Genetic architecture of subcortical brain structures in 38,851 individuals

scientific article published on 21 October 2019

Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults

scientific article published on 22 September 2020

Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.

scientific article published on 4 December 2018

Genetic data and cognitively-defined late-onset Alzheimer's disease subgroups

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD

scientific article published on 09 February 2019

Genome-wide analysis of genetic loci associated with Alzheimer disease

scientific article

Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium

scientific article

Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium

scientific article

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

scientific article published in Nature Communications

Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium

scientific article

Genomewide association studies of stroke

scientific article published on 15 April 2009

Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk

scientific article

Hippocampal sclerosis, TDP-43, and the duration of the symptoms of dementia of AD patients

scientific article published on 31 July 2020

Hippocampal volume is related to body mass index in Alzheimer's disease

scientific article

Joint effect of mid- and late-life blood pressure on the brain: the AGES-Reykjavik study

scientific article

Mapping cerebellar degeneration in HIV/AIDS

scientific article

Mean template for tensor-based morphometry using deformation tensors

scientific article published on 01 January 2007

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 12 March 2018

Multivariate statistics of the Jacobian matrices in tensor based morphometry and their application to HIV/AIDS

article

Multivariate tensor-based morphometry on surfaces: application to mapping ventricular abnormalities in HIV/AIDS.

scientific article published on 6 November 2009

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis ⬇️

scientific article published on 19 October 2020

Novel genetic loci associated with hippocampal volume

scientific article published on 18 January 2017

Novel genetic loci underlying human intracranial volume identified through genome-wide association

scientific article (publication date: 3 October 2016)

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

scientific article

Obesity is linked with lower brain volume in 700 AD and MCI patients

scientific article

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

scientific article

Pulmonary function impairment may be an early risk factor for late-life cognitive impairment

scientific article published on January 2013

Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease

scientific article

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease

scientific article

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

scientific article

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

scientific article published on 29 May 2018

The effect of midlife physical activity on cognitive function among older adults: AGES--Reykjavik Study

scientific article

The effects of physical activity, education, and body mass index on the aging brain

scientific article

The genetic architecture of the human cerebral cortex

scientific article

Thinning of the cerebral cortex visualized in HIV/AIDS reflects CD4+ T lymphocyte decline

scientific article

Three-dimensional Patterns of Hippocampal Atrophy in Mild Cognitive Impairment

scientific article published on 01 January 2006

Tracking Alzheimer's disease

scientific article

Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans

scientific article

Ventricular volume and dementia progression in the Cardiovascular Health Study

scientific article

List of works by Oscar L Lopez

18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

3D mapping of ventricular and corpus callosum abnormalities in HIV/AIDS.

3D pattern of brain atrophy in HIV/AIDS visualized using tensor-based morphometry

A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

Association of Alzheimer's disease GWAS loci with MRI markers of brain aging

Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

Brain structure and obesity

Cerebral small vessel disease genomics and its implications across the lifespan

Cerebral ventricular changes associated with transitions between normal cognitive function, mild cognitive impairment, and dementia

Common folate gene variant, MTHFR C677T, is associated with brain structure in two independent cohorts of people with mild cognitive impairment

Common variants at 12q14 and 12q24 are associated with hippocampal volume

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

Correction: Genetic data and cognitively defined late-onset Alzheimer's disease subgroups

Developing a national strategy to prevent dementia: Leon Thal Symposium 2009.

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

Estrogen, brain structure, and cognition in postmenopausal women

Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease

Fast 3D Fluid Registration of Brain Magnetic Resonance Images.

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Genetic architecture of subcortical brain structures in 38,851 individuals

Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults

Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.

Genetic data and cognitively-defined late-onset Alzheimer's disease subgroups

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD

Genome-wide analysis of genetic loci associated with Alzheimer disease

Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium

Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium

Genomewide association studies of stroke

Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk

Hippocampal sclerosis, TDP-43, and the duration of the symptoms of dementia of AD patients

Hippocampal volume is related to body mass index in Alzheimer's disease

Joint effect of mid- and late-life blood pressure on the brain: the AGES-Reykjavik study

Mapping cerebellar degeneration in HIV/AIDS

Mean template for tensor-based morphometry using deformation tensors

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Multivariate statistics of the Jacobian matrices in tensor based morphometry and their application to HIV/AIDS

Multivariate tensor-based morphometry on surfaces: application to mapping ventricular abnormalities in HIV/AIDS.

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis ⬇️

Novel genetic loci associated with hippocampal volume

Novel genetic loci underlying human intracranial volume identified through genome-wide association

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

Obesity is linked with lower brain volume in 700 AD and MCI patients

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

Pulmonary function impairment may be an early risk factor for late-life cognitive impairment

Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

The effect of midlife physical activity on cognitive function among older adults: AGES--Reykjavik Study

The effects of physical activity, education, and body mass index on the aging brain

The genetic architecture of the human cerebral cortex

The genetic architecture of the human cerebral cortex

Thinning of the cerebral cortex visualized in HIV/AIDS reflects CD4+ T lymphocyte decline

Three-dimensional Patterns of Hippocampal Atrophy in Mild Cognitive Impairment

Tracking Alzheimer's disease

Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans

Ventricular volume and dementia progression in the Cardiovascular Health Study