List of works - Michael Kahl

A graphical systems model to facilitate hypothesis-driven ecotoxicogenomics research on the teleost brain-pituitary-gonadal axis

scientific article

A study of temporal effects of the model anti-androgen flutamide on components of the hypothalamic-pituitary-gonadal axis in adult fathead minnows

scientific article published in October 2016

A time-course analysis of effects of the steroidogenesis inhibitor ketoconazole on components of the hypothalamic-pituitary-gonadal axis of fathead minnows

scientific article published on 22 February 2012

Adverse Outcome Pathway Network-Based Assessment of the Interactive Effects of an Androgen Receptor Agonist and an Aromatase Inhibitor on Fish Endocrine Function

scientific article published on 21 February 2020

An inexpensive, temporally integrated system for monitoring occurrence and biological effects of aquatic contaminants in the field

scientific article published on 20 May 2014

An integrated approach for identifying priority contaminant in the Great Lakes Basin - Investigations in the Lower Green Bay/Fox River and Milwaukee Estuary areas of concern

scientific article published on 17 November 2016

Case study in 21<sup>st</sup> century ecotoxicology: using in vitro aromatase inhibition data to predict short term in vivo responses in adult female fish

scientific article published on 17 December 2020

Cross-species sensitivity to a novel androgen receptor agonist of potential environmental concern, spironolactone

scientific article published on 6 September 2013

Derivation and Evaluation of Putative Adverse Outcome Pathways for the Effects of Cyclooxygenase Inhibitors on Reproductive Processes in Female Fish.

scientific article published on 13 February 2017

Development of quantitative real-time PCR assays for fathead minnow (Pimephales promelas) gonadotropin beta subunit mRNAs to support endocrine disruptor research

scientific article

Differential Sensitivity to In Vitro Inhibition of Cytochrome P450 Aromatase (CYP19) Activity Among 18 Freshwater Fishes

scientific article published on 01 August 2019

Direct effects, compensation, and recovery in female fathead minnows exposed to a model aromatase inhibitor

scientific article published on 12 December 2008

Dynamic nature of alterations in the endocrine system of fathead minnows exposed to the fungicide prochloraz

scientific article published on 18 September 2009

Ecotoxicogenomics to support ecological risk assessment: a case study with bisphenol A in fish

scientific article published on 5 August 2011

Effects of a 3beta-hydroxysteroid dehydrogenase inhibitor, trilostane, on the fathead minnow reproductive axis

scientific article published on 7 April 2008

Effects of a glucocorticoid receptor agonist, dexamethasone, on fathead minnow reproduction, growth, and development

scientific article published on 6 February 2012

Effects of a short-term exposure to the fungicide prochloraz on endocrine function and gene expression in female fathead minnows (Pimephales promelas).

scientific article published on 2 March 2011

Effects of gemfibrozil on lipid metabolism, steroidogenesis, and reproduction in the fathead minnow (Pimephales promelas)

scientific article published on 19 September 2012

Effects of the antimicrobial contaminant triclocarban, and co-exposure with the androgen 17β-trenbolone, on reproductive function and ovarian transcriptome of the fathead minnow (Pimephales promelas).

scientific article published on 17 June 2016

Effects of the insecticide fipronil on reproductive endocrinology in the fathead minnow

scientific article published on 21 June 2013

Effects of two fungicides with multiple modes of action on reproductive endocrine function in the fathead minnow (Pimephales promelas).

scientific article published on 18 May 2005

Evaluation of the methoxytriazine herbicide prometon using a short-term fathead minnow reproduction test and a suite of in vitro bioassays

scientific article published in August 2006

Hypoxia alters gene expression in the gonads of zebrafish (Danio rerio).

scientific article published on 19 September 2008

I. Effects of a dopamine receptor antagonist on fathead minnow, Pimephales promelas, reproduction

scientific article published on 26 September 2009

II: Effects of a dopamine receptor antagonist on fathead minnow dominance behavior and ovarian gene expression in the fathead minnow and zebrafish

scientific article published on 7 November 2009

Impacts of an anti-androgen and an androgen/anti-androgen mixture on the metabolite profile of male fathead minnow urine

scientific article

Impaired anterior swim bladder inflation following exposure to the thyroid peroxidase inhibitor 2-mercaptobenzothiazole part I: Fathead minnow.

scientific article published on 7 January 2016

Impaired swim bladder inflation in early life stage fathead minnows exposed to a deiodinase inhibitor, iopanoic acid

scientific article published on 10 May 2017

Influence of ovarian stage on transcript profiles in fathead minnow (Pimephales promelas) ovary tissue

scientific article

Integrated assessment of runoff from livestock farming operations: Analytical chemistry, in vitro bioassays, and in vivo fish exposures

scientific article published on 27 June 2014

Ketoconazole in the fathead minnow (Pimephales promelas): reproductive toxicity and biological compensation.

scientific article published in June 2007

Linkage of biochemical responses to population-level effects: a case study with vitellogenin in the fathead minnow (Pimephales promelas).

scientific article published in March 2007

Linking field-based metabolomics and chemical analyses to prioritize contaminants of emerging concern in the Great Lakes basin

scientific article

Metabolite profiles of repeatedly sampled urine from male fathead minnows (Pimephales promelas) contain unique lipid signatures following exposure to anti-androgens

scientific article

Pathway-based approaches for assessment of real-time exposure to an estrogenic wastewater treatment plant effluent on fathead minnow reproduction

scientific article

Prioritization of Contaminants of Emerging Concern in Wastewater Treatment Plant Discharges Using Chemical:Gene Interactions in Caged Fish.

scientific article

Propiconazole inhibits steroidogenesis and reproduction in the fathead minnow (Pimephales promelas).

scientific article published on 20 January 2013

Quantitative Response-Response Relationships Linking Aromatase Inhibition to Decreased Fecundity are Conserved Across Three Fishes with Asynchronous Oocyte Development

scientific article published on 14 August 2019

Rapid effects of the aromatase inhibitor fadrozole on steroid production and gene expression in the ovary of female fathead minnows (Pimephales promelas).

scientific article

Re-evaluating the Significance of Estrone as an Environmental Estrogen.

scientific article published on 22 March 2017

Relationship between brain and ovary aromatase activity and isoform-specific aromatase mRNA expression in the fathead minnow (Pimephales promelas).

scientific article published on 2 December 2005

Reproductive toxicity of vinclozolin in the fathead minnow: confirming an anti-androgenic mode of action

scientific article

Resilience and cortical thickness: a MRI study

scientific article published on 12 December 2018

Screening complex effluents for estrogenic activity with the T47D-KBluc cell bioassay: assay optimization and comparison with in vivo responses in fish

scientific article published on February 2011

Short-term study investigating the estrogenic potency of diethylstilbesterol in the fathead minnow (Pimephales promelas).

scientific article

Temporal evaluation of effects of a model 3β-hydroxysteroid dehydrogenase inhibitor on endocrine function in the fathead minnow.

scientific article published on 9 July 2011

Use of chemical mixtures to differentiate mechanisms of endocrine action in a small fish model

scientific article published on 4 June 2010

Use of gene expression, biochemical and metabolite profiles to enhance exposure and effects assessment of the model androgen 17β-trenbolone in fish

scientific article

List of works by Michael Kahl

A graphical systems model to facilitate hypothesis-driven ecotoxicogenomics research on the teleost brain-pituitary-gonadal axis

A study of temporal effects of the model anti-androgen flutamide on components of the hypothalamic-pituitary-gonadal axis in adult fathead minnows

A time-course analysis of effects of the steroidogenesis inhibitor ketoconazole on components of the hypothalamic-pituitary-gonadal axis of fathead minnows

Adverse Outcome Pathway Network-Based Assessment of the Interactive Effects of an Androgen Receptor Agonist and an Aromatase Inhibitor on Fish Endocrine Function

An inexpensive, temporally integrated system for monitoring occurrence and biological effects of aquatic contaminants in the field

An integrated approach for identifying priority contaminant in the Great Lakes Basin - Investigations in the Lower Green Bay/Fox River and Milwaukee Estuary areas of concern

Case study in 21<sup>st</sup> century ecotoxicology: using in vitro aromatase inhibition data to predict short term in vivo responses in adult female fish

Cross-species sensitivity to a novel androgen receptor agonist of potential environmental concern, spironolactone

Derivation and Evaluation of Putative Adverse Outcome Pathways for the Effects of Cyclooxygenase Inhibitors on Reproductive Processes in Female Fish.

Development of quantitative real-time PCR assays for fathead minnow (Pimephales promelas) gonadotropin beta subunit mRNAs to support endocrine disruptor research

Differential Sensitivity to In Vitro Inhibition of Cytochrome P450 Aromatase (CYP19) Activity Among 18 Freshwater Fishes

Direct effects, compensation, and recovery in female fathead minnows exposed to a model aromatase inhibitor

Dynamic nature of alterations in the endocrine system of fathead minnows exposed to the fungicide prochloraz

Ecotoxicogenomics to support ecological risk assessment: a case study with bisphenol A in fish

Effects of a 3beta-hydroxysteroid dehydrogenase inhibitor, trilostane, on the fathead minnow reproductive axis

Effects of a glucocorticoid receptor agonist, dexamethasone, on fathead minnow reproduction, growth, and development

Effects of a short-term exposure to the fungicide prochloraz on endocrine function and gene expression in female fathead minnows (Pimephales promelas).

Effects of gemfibrozil on lipid metabolism, steroidogenesis, and reproduction in the fathead minnow (Pimephales promelas)

Effects of the antimicrobial contaminant triclocarban, and co-exposure with the androgen 17β-trenbolone, on reproductive function and ovarian transcriptome of the fathead minnow (Pimephales promelas).

Effects of the insecticide fipronil on reproductive endocrinology in the fathead minnow

Effects of two fungicides with multiple modes of action on reproductive endocrine function in the fathead minnow (Pimephales promelas).

Evaluation of the methoxytriazine herbicide prometon using a short-term fathead minnow reproduction test and a suite of in vitro bioassays

Hypoxia alters gene expression in the gonads of zebrafish (Danio rerio).

I. Effects of a dopamine receptor antagonist on fathead minnow, Pimephales promelas, reproduction

II: Effects of a dopamine receptor antagonist on fathead minnow dominance behavior and ovarian gene expression in the fathead minnow and zebrafish

Impacts of an anti-androgen and an androgen/anti-androgen mixture on the metabolite profile of male fathead minnow urine

Impaired anterior swim bladder inflation following exposure to the thyroid peroxidase inhibitor 2-mercaptobenzothiazole part I: Fathead minnow.

Impaired swim bladder inflation in early life stage fathead minnows exposed to a deiodinase inhibitor, iopanoic acid

Influence of ovarian stage on transcript profiles in fathead minnow (Pimephales promelas) ovary tissue

Integrated assessment of runoff from livestock farming operations: Analytical chemistry, in vitro bioassays, and in vivo fish exposures

Ketoconazole in the fathead minnow (Pimephales promelas): reproductive toxicity and biological compensation.

Linkage of biochemical responses to population-level effects: a case study with vitellogenin in the fathead minnow (Pimephales promelas).

Linking field-based metabolomics and chemical analyses to prioritize contaminants of emerging concern in the Great Lakes basin

Metabolite profiles of repeatedly sampled urine from male fathead minnows (Pimephales promelas) contain unique lipid signatures following exposure to anti-androgens

Pathway-based approaches for assessment of real-time exposure to an estrogenic wastewater treatment plant effluent on fathead minnow reproduction

Prioritization of Contaminants of Emerging Concern in Wastewater Treatment Plant Discharges Using Chemical:Gene Interactions in Caged Fish.

Propiconazole inhibits steroidogenesis and reproduction in the fathead minnow (Pimephales promelas).

Quantitative Response-Response Relationships Linking Aromatase Inhibition to Decreased Fecundity are Conserved Across Three Fishes with Asynchronous Oocyte Development

Rapid effects of the aromatase inhibitor fadrozole on steroid production and gene expression in the ovary of female fathead minnows (Pimephales promelas).

Re-evaluating the Significance of Estrone as an Environmental Estrogen.

Relationship between brain and ovary aromatase activity and isoform-specific aromatase mRNA expression in the fathead minnow (Pimephales promelas).

Reproductive toxicity of vinclozolin in the fathead minnow: confirming an anti-androgenic mode of action

Resilience and cortical thickness: a MRI study

Screening complex effluents for estrogenic activity with the T47D-KBluc cell bioassay: assay optimization and comparison with in vivo responses in fish

Short-term study investigating the estrogenic potency of diethylstilbesterol in the fathead minnow (Pimephales promelas).

Temporal evaluation of effects of a model 3β-hydroxysteroid dehydrogenase inhibitor on endocrine function in the fathead minnow.

Use of chemical mixtures to differentiate mechanisms of endocrine action in a small fish model

Use of gene expression, biochemical and metabolite profiles to enhance exposure and effects assessment of the model androgen 17β-trenbolone in fish