List of works - Hiroto Furuta

A Case of Liver Abscess Caused by Edwardsiella tardaa ⬇️

scientific article published on January 1, 2011

A case report of autoimmune pancreatitis with Mikulicz' s disease and diabetes mellitus

scientific article published in February 2006

A family in which people with a heterozygous ABCC8 gene mutation (p.Lys1385Gln) have progressed from hyperinsulinemic hypoglycemia to hyperglycemia

scientific article published on 21 October 2019

A functional variant in the human betacellulin gene promoter is associated with type 2 diabetes

scientific article

A novel immunopathological association of IgG4-RD and vasculitis with Hashimoto's thyroiditis

scientific article

Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects

scientific article

Atypical pituitary adenoma with MEN1 somatic mutation associated with abnormalities of DNA mismatch repair genes; MLH1 germline mutation and MSH6 somatic mutation

scientific article published on 13 July 2017

Cardio-ankle vascular index measures arterial wall stiffness independent of blood pressure

scientific article

Clinical and functional characterization of the Pro1198Leu ABCC8 gene mutation associated with permanent neonatal diabetes mellitus

scientific article

Clinical polyneuropathy does not increase with prediabetes or metabolic syndrome in the Japanese general population

scientific article published on 14 May 2019

Construction of a prediction model for type 2 diabetes mellitus in the Japanese population based on 11 genes with strong evidence of the association

scientific article published on 27 February 2009

Defective PAX4 R192H transcriptional repressor activities associated with maturity onset diabetes of the young and early onset-age of type 2 diabetes ⬇️

scientific article published on April 20, 2012

Des-acyl ghrelin protects microvascular endothelial cells from oxidative stress-induced apoptosis through sirtuin 1 signaling pathway

scientific article published on 28 December 2013

Early detection of euglycemic ketoacidosis during thoracic surgery associated with empagliflozin in a patient with type 2 diabetes: A case report

scientific article published on 19 July 2020

Effect of anti-oxidants, Ricetrienol and α-tocopherol, on adipocytokine abnormalities and fatty liver in Otsuka Long-Evans Tokushima Fatty diabetic rats

scientific article published on June 2011

Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese

scientific article published on 20 January 2014

Ferulic acid prevents pathological and functional abnormalities of the kidney in Otsuka Long-Evans Tokushima Fatty diabetic rats

scientific article published on 25 September 2007

Functional defect of truncated hepatocyte nuclear factor-1alpha (G554fsX556) associated with maturity-onset diabetes of the young

scientific article

Functional variants in the glutathione peroxidase-1 (GPx-1) gene are associated with increased intima-media thickness of carotid arteries and risk of macrovascular diseases in japanese type 2 diabetic patients

scientific article

Genetic associations of type 2 diabetes with islet amyloid polypeptide processing and degrading pathways in asian populations

scientific article

Ghrelin inhibits insulin secretion through the AMPK-UCP2 pathway in beta cells

scientific article

Graves' Disease in Pediatric and Elderly Patients with 22q11.2 Deletion Syndrome.

scientific article

History of obesity as a risk factor for both carotid atherosclerosis and microangiopathy

scientific article

Hypersecretion of ACTH and PRL from pituitary adenoma in MEN1, adequately managed by medical therapy

scientific article published on 6 April 2017

IA-2beta, but not IA-2, is induced by ghrelin and inhibits glucose-stimulated insulin secretion

scientific article

IL-1β directly suppress ghrelin mRNA expression in ghrelin-producing cells.

scientific article published on 22 February 2017

Identification of a compound heterozygous inactivating ABCC8 gene mutation responsible for young-onset diabetes with exome sequencing

scientific article published on 19 September 2019

Identification of a variant-associated with early-onset diabetes in the intron of INS gene with exome sequencing

article

Increased arterial stiffness is closely associated with hyperglycemia and improved by glycemic control in diabetic patients

scientific article

Increased gene expression of antioxidant enzymes in KKAy diabetic mice but not in STZ diabetic mice

scientific article published in August 2005

Kir6.2 E23K polymorphism is related to secondary failure of sulfonylureas in non-obese patients with type 2 diabetes

scientific article

Molecular scanning of the betacellulin gene for mutations in type 2 diabetic patients

scientific article

Negative pressure suction during blood sampling may reduce the difference in self-monitoring of blood glucose results between fingertip pricking and forearm pricking

scientific article published in June 2004

Neonatal diabetes caused by the heterozygous Pro1198Leu mutation in the ABCC8 gene in a male infant: 6-year clinical course

scientific article published on 27 August 2019

Neurosarcoidosis with spinal root pain as the first symptom

scientific article published in September 2004

Nicotinic acetylcholine receptor signaling regulates inositol-requiring enzyme 1α activation to protect β-cells against terminal unfolded protein response under irremediable endoplasmic reticulum stress

scientific article published on 10 January 2020

Nonsense and missense mutations in the human hepatocyte nuclear factor-1 beta gene (TCF2) and their relation to type 2 diabetes in Japanese

scientific article

Numbness and paresthesia in bilateral toes and soles, and disproportional sweating restricted to face and trunk are suitable symptoms useful for the diagnosis of diabetic symmetric polyneuropathy

scientific article

Oncostatin M is a potential agent for the treatment of obesity and related metabolic disorders: a study in mice

scientific article published on 14 May 2015

Pro198Leu missense polymorphism of the glutathione peroxidase 1 gene might be a common genetic predisposition of distal symmetric polyneuropathy and macrovascular disease in Japanese type 2 diabetic patients

scientific article

Regulation of AMP-activated Protein Kinase Signaling by AFF4 Protein, Member of AF4 (ALL1-fused Gene from Chromosome 4) Family of Transcription Factors, in Hypothalamic Neurons ⬇️

scientific article published on April 23, 2012

Regulation of Ghrelin Signaling by a Leptin-induced Gene, Negative Regulatory Element-binding Protein, in the Hypothalamic Neurons ⬇️

scientific article published on September 28, 2010

Rice bran extract prevents the elevation of plasma peroxylipid in KKAy diabetic mice

scientific article published in December 2004

SUMO4 Met55Val polymorphism is associated with coronary heart disease in Japanese type 2 diabetes individuals.

scientific article published in May 2009

Truncal pruritus of unknown origin may be a symptom of diabetic polyneuropathy

scientific article

Uncoupling protein 2 promoter polymorphism -866G/A affects its expression in beta-cells and modulates clinical profiles of Japanese type 2 diabetic patients

scientific article published on February 2004

List of works by Hiroto Furuta

A Case of Liver Abscess Caused by Edwardsiella tardaa ⬇️

A case report of autoimmune pancreatitis with Mikulicz' s disease and diabetes mellitus

A family in which people with a heterozygous ABCC8 gene mutation (p.Lys1385Gln) have progressed from hyperinsulinemic hypoglycemia to hyperglycemia

A functional variant in the human betacellulin gene promoter is associated with type 2 diabetes

A novel immunopathological association of IgG4-RD and vasculitis with Hashimoto's thyroiditis

Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects

Atypical pituitary adenoma with MEN1 somatic mutation associated with abnormalities of DNA mismatch repair genes; MLH1 germline mutation and MSH6 somatic mutation

Cardio-ankle vascular index measures arterial wall stiffness independent of blood pressure

Clinical and functional characterization of the Pro1198Leu ABCC8 gene mutation associated with permanent neonatal diabetes mellitus

Clinical polyneuropathy does not increase with prediabetes or metabolic syndrome in the Japanese general population

Construction of a prediction model for type 2 diabetes mellitus in the Japanese population based on 11 genes with strong evidence of the association

Defective PAX4 R192H transcriptional repressor activities associated with maturity onset diabetes of the young and early onset-age of type 2 diabetes ⬇️

Des-acyl ghrelin protects microvascular endothelial cells from oxidative stress-induced apoptosis through sirtuin 1 signaling pathway

Early detection of euglycemic ketoacidosis during thoracic surgery associated with empagliflozin in a patient with type 2 diabetes: A case report

Effect of anti-oxidants, Ricetrienol and α-tocopherol, on adipocytokine abnormalities and fatty liver in Otsuka Long-Evans Tokushima Fatty diabetic rats

Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese

Ferulic acid prevents pathological and functional abnormalities of the kidney in Otsuka Long-Evans Tokushima Fatty diabetic rats

Functional defect of truncated hepatocyte nuclear factor-1alpha (G554fsX556) associated with maturity-onset diabetes of the young

Functional variants in the glutathione peroxidase-1 (GPx-1) gene are associated with increased intima-media thickness of carotid arteries and risk of macrovascular diseases in japanese type 2 diabetic patients

Genetic associations of type 2 diabetes with islet amyloid polypeptide processing and degrading pathways in asian populations

Ghrelin inhibits insulin secretion through the AMPK-UCP2 pathway in beta cells

Graves' Disease in Pediatric and Elderly Patients with 22q11.2 Deletion Syndrome.

History of obesity as a risk factor for both carotid atherosclerosis and microangiopathy

Hypersecretion of ACTH and PRL from pituitary adenoma in MEN1, adequately managed by medical therapy

IA-2beta, but not IA-2, is induced by ghrelin and inhibits glucose-stimulated insulin secretion

IL-1β directly suppress ghrelin mRNA expression in ghrelin-producing cells.

Identification of a compound heterozygous inactivating ABCC8 gene mutation responsible for young-onset diabetes with exome sequencing

Identification of a variant-associated with early-onset diabetes in the intron of INS gene with exome sequencing

Increased arterial stiffness is closely associated with hyperglycemia and improved by glycemic control in diabetic patients

Increased gene expression of antioxidant enzymes in KKAy diabetic mice but not in STZ diabetic mice

Kir6.2 E23K polymorphism is related to secondary failure of sulfonylureas in non-obese patients with type 2 diabetes

Molecular scanning of the betacellulin gene for mutations in type 2 diabetic patients

Negative pressure suction during blood sampling may reduce the difference in self-monitoring of blood glucose results between fingertip pricking and forearm pricking

Neonatal diabetes caused by the heterozygous Pro1198Leu mutation in the ABCC8 gene in a male infant: 6-year clinical course

Neurosarcoidosis with spinal root pain as the first symptom

Nicotinic acetylcholine receptor signaling regulates inositol-requiring enzyme 1α activation to protect β-cells against terminal unfolded protein response under irremediable endoplasmic reticulum stress

Nonsense and missense mutations in the human hepatocyte nuclear factor-1 beta gene (TCF2) and their relation to type 2 diabetes in Japanese

Numbness and paresthesia in bilateral toes and soles, and disproportional sweating restricted to face and trunk are suitable symptoms useful for the diagnosis of diabetic symmetric polyneuropathy

Oncostatin M is a potential agent for the treatment of obesity and related metabolic disorders: a study in mice

Pro198Leu missense polymorphism of the glutathione peroxidase 1 gene might be a common genetic predisposition of distal symmetric polyneuropathy and macrovascular disease in Japanese type 2 diabetic patients

Regulation of AMP-activated Protein Kinase Signaling by AFF4 Protein, Member of AF4 (ALL1-fused Gene from Chromosome 4) Family of Transcription Factors, in Hypothalamic Neurons ⬇️

Regulation of Ghrelin Signaling by a Leptin-induced Gene, Negative Regulatory Element-binding Protein, in the Hypothalamic Neurons ⬇️

Rice bran extract prevents the elevation of plasma peroxylipid in KKAy diabetic mice

SUMO4 Met55Val polymorphism is associated with coronary heart disease in Japanese type 2 diabetes individuals.

Truncal pruritus of unknown origin may be a symptom of diabetic polyneuropathy

Uncoupling protein 2 promoter polymorphism -866G/A affects its expression in beta-cells and modulates clinical profiles of Japanese type 2 diabetic patients