List of works - Michael J Overman

4-1BB Agonist Focuses CD8+ Tumor-Infiltrating T-Cell Growth into a Distinct Repertoire Capable of Tumor Recognition in Pancreatic Cancer.

scientific article

A Simplified Preoperative Assessment Predicts Complete Cytoreduction and Outcomes in Patients with Low-Grade Mucinous Adenocarcinoma of the Appendix

scientific article

A population-based comparison of adenocarcinoma of the large and small intestine: insights into a rare disease

scientific article published on 21 December 2011

A randomized, double-blind, 2-period, placebo-controlled crossover trial of a sustained-release methylphenidate in the treatment of fatigue in cancer patients

scientific article published in January 2014

ABO non-O type as a risk factor for thrombosis in patients with pancreatic cancer

scientific article published on 15 August 2015

ARID1A mutation may define an immunologically active subgroup in patients with microsatellite-stable colorectal cancer

scientific article published on 07 January 2021

Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies

scientific article published in May 2015

Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation.

scientific article published on 19 January 2016

Association of CHFR promoter methylation with disease recurrence in locally advanced colon cancer

scientific article published on 6 May 2011

Association of Clinical Factors With a Major Pathologic Response Following Preoperative Therapy for Pancreatic Ductal Adenocarcinoma

scientific article

Association of SMAD4 mutation with patient demographics, tumor characteristics, and clinical outcomes in colorectal cancer

scientific article

Beyond VEGF: inhibition of the fibroblast growth factor pathway and antiangiogenesis

scientific article

Cancer of Unknown Primary in Adolescents and Young Adults: Clinicopathological Features, Prognostic Factors and Survival Outcomes

scientific article

Clinicopathologic features and prognosis of duodenal adenocarcinoma and comparison with ampullary and pancreatic ductal adenocarcinoma

scientific article

Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer

scientific article published on 11 January 2019

DNA Sequencing of Small Bowel Adenocarcinomas Identifies Targetable Recurrent Mutations in the ERBB2 Signaling Pathway

scientific article published on 23 October 2018

Development and Validation of a Gene Signature Classifier for Consensus Molecular Subtyping of Colorectal Carcinoma in a CLIA-Certified Setting

scientific article published on 27 October 2020

Discrepancies in endpoints between clinical trial protocols and clinical trial registration in randomized trials in oncology

scientific article published on 12 December 2018

Does IGFR1 inhibition result in increased muscle mass loss in patients undergoing treatment for pancreatic cancer?

scientific article

EGFR-targeted therapies in colorectal cancer

scientific article published on August 2007

Epithelial-mesenchymal transitioned circulating tumor cells capture for detecting tumor progression

scientific article

FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma.

scientific article

Facile profiling of molecular heterogeneity by microfluidic digital melt

scientific article published on 28 September 2018

First-in-human trial of multikinase VEGF inhibitor regorafenib and anti-EGFR antibody cetuximab in advanced cancer patients

scientific article

From Protocols to Publications: A Study in Selective Reporting of Outcomes in Randomized Trials in Oncology

scientific article (publication date: November 2015)

Gene expression profiling of ampullary carcinomas classifies ampullary carcinomas into biliary-like and intestinal-like subtypes that are prognostic of outcome

scientific article published on 11 June 2013

Germline DNA Sequencing Reveals Novel Mutations Predictive of Overall Survival in a Cohort of Patients with Pancreatic Cancer

scientific article published on 23 December 2019

High survival rate after two-stage resection of advanced colorectal liver metastases: response-based selection and complete resection define outcome

scientific article

High-Grade Neuroendocrine Colorectal Carcinomas: A Retrospective Study of 100 Patients

scientific article published on 29 December 2015

High-level Microsatellite Instability in Appendiceal Carcinomas ⬇️

scientific article published on August 1, 2013

Imaging-based biomarkers: Changes in the tumor interface of pancreatic ductal adenocarcinoma on computed tomography scans indicate response to cytotoxic therapy

scientific article

Impact of hypofractionated and standard fractionated chemoradiation before pancreatoduodenectomy for pancreatic ductal adenocarcinoma

scientific article published on 31 May 2016

Influence of Preoperative Therapy on Short- and Long-Term Outcomes of Patients with Adenocarcinoma of the Ampulla of Vater

scientific article published on 25 January 2017

Is resection of colorectal liver metastases after a second-line chemotherapy regimen justified?

scientific article

Mismatch Repair-Proficient Colorectal Cancer: Finding the Right TiME to Respond

scientific article published on 01 July 2019

Oxaliplatin-mediated increase in spleen size as a biomarker for the development of hepatic sinusoidal injury

scientific article

Palliative Venting Gastrostomy in Patients with Malignant Bowel Obstruction and Ascites ⬇️

scientific article published on September 11, 2012

Performance and prognostic utility of the 92-gene assay in the molecular subclassification of ampullary adenocarcinoma

scientific article

Phase II study of capecitabine and oxaliplatin for advanced adenocarcinoma of the small bowel and ampulla of Vater.

scientific article

Phase II trial of infusional fluorouracil, irinotecan, and bevacizumab for metastatic colorectal cancer: efficacy and circulating angiogenic biomarkers associated with therapeutic resistance

scientific article

Portal hypertension associated with oxaliplatin administration: clinical manifestations of hepatic sinusoidal injury

scientific article

Preoperative Therapy and Pancreatoduodenectomy for Pancreatic Ductal Adenocarcinoma: a 25-Year Single-Institution Experience

scientific article published on 24 October 2016

Progression-free survival remains poor over sequential lines of systemic therapy in patients with BRAF-mutated colorectal cancer

scientific article

Recent advances in the management of adenocarcinoma of the small intestine.

scientific article

Retrospective analysis of systemic chemotherapy and total parenteral nutrition for the treatment of malignant small bowel obstruction

scientific article published on 29 December 2015

Retrospective study of nonmucinous appendiceal adenocarcinomas: role of systemic chemotherapy and cytoreductive surgery

scientific article

Second-line chemotherapy use in metastatic colon cancer varies by disease responsiveness.

scientific article published on January 2008

Src activity is modulated by oxaliplatin and correlates with outcomes after hepatectomy for metastatic colorectal cancer.

scientific article

Systematic survey of therapeutic trials for metastatic colorectal cancer: room for improvement in the critical pathway

scientific article published on April 2008

Target-based therapeutic matching in early-phase clinical trials in patients with advanced colorectal cancer and PIK3CA mutations

scientific article

The association of alternate VEGF ligands with resistance to anti-VEGF therapy in metastatic colorectal cancer

scientific article

The expression of PTEN is associated with improved prognosis in patients with ampullary adenocarcinoma after pancreaticoduodenectomy

scientific article

The impact of stage, grade, and mucinous histology on the efficacy of systemic chemotherapy in adenocarcinomas of the appendix: Analysis of the National Cancer Data Base

scientific article

Worsening of thrombotic thromboctyopenic purpura symptoms associated with desmopressin administration

scientific article

List of works by Michael J Overman

4-1BB Agonist Focuses CD8+ Tumor-Infiltrating T-Cell Growth into a Distinct Repertoire Capable of Tumor Recognition in Pancreatic Cancer.

A Simplified Preoperative Assessment Predicts Complete Cytoreduction and Outcomes in Patients with Low-Grade Mucinous Adenocarcinoma of the Appendix

A population-based comparison of adenocarcinoma of the large and small intestine: insights into a rare disease

A randomized, double-blind, 2-period, placebo-controlled crossover trial of a sustained-release methylphenidate in the treatment of fatigue in cancer patients

ABO non-O type as a risk factor for thrombosis in patients with pancreatic cancer

ARID1A mutation may define an immunologically active subgroup in patients with microsatellite-stable colorectal cancer

Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies

Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation.

Association of CHFR promoter methylation with disease recurrence in locally advanced colon cancer

Association of Clinical Factors With a Major Pathologic Response Following Preoperative Therapy for Pancreatic Ductal Adenocarcinoma

Association of SMAD4 mutation with patient demographics, tumor characteristics, and clinical outcomes in colorectal cancer

Beyond VEGF: inhibition of the fibroblast growth factor pathway and antiangiogenesis

Cancer of Unknown Primary in Adolescents and Young Adults: Clinicopathological Features, Prognostic Factors and Survival Outcomes

Clinicopathologic features and prognosis of duodenal adenocarcinoma and comparison with ampullary and pancreatic ductal adenocarcinoma

Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer

DNA Sequencing of Small Bowel Adenocarcinomas Identifies Targetable Recurrent Mutations in the ERBB2 Signaling Pathway

Development and Validation of a Gene Signature Classifier for Consensus Molecular Subtyping of Colorectal Carcinoma in a CLIA-Certified Setting

Discrepancies in endpoints between clinical trial protocols and clinical trial registration in randomized trials in oncology

Does IGFR1 inhibition result in increased muscle mass loss in patients undergoing treatment for pancreatic cancer?

EGFR-targeted therapies in colorectal cancer

Epithelial-mesenchymal transitioned circulating tumor cells capture for detecting tumor progression

FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma.

Facile profiling of molecular heterogeneity by microfluidic digital melt

First-in-human trial of multikinase VEGF inhibitor regorafenib and anti-EGFR antibody cetuximab in advanced cancer patients

From Protocols to Publications: A Study in Selective Reporting of Outcomes in Randomized Trials in Oncology

Gene expression profiling of ampullary carcinomas classifies ampullary carcinomas into biliary-like and intestinal-like subtypes that are prognostic of outcome

Germline DNA Sequencing Reveals Novel Mutations Predictive of Overall Survival in a Cohort of Patients with Pancreatic Cancer

High survival rate after two-stage resection of advanced colorectal liver metastases: response-based selection and complete resection define outcome

High-Grade Neuroendocrine Colorectal Carcinomas: A Retrospective Study of 100 Patients

High-level Microsatellite Instability in Appendiceal Carcinomas ⬇️

Imaging-based biomarkers: Changes in the tumor interface of pancreatic ductal adenocarcinoma on computed tomography scans indicate response to cytotoxic therapy

Impact of hypofractionated and standard fractionated chemoradiation before pancreatoduodenectomy for pancreatic ductal adenocarcinoma

Influence of Preoperative Therapy on Short- and Long-Term Outcomes of Patients with Adenocarcinoma of the Ampulla of Vater

Is resection of colorectal liver metastases after a second-line chemotherapy regimen justified?

Mismatch Repair-Proficient Colorectal Cancer: Finding the Right TiME to Respond

Oxaliplatin-mediated increase in spleen size as a biomarker for the development of hepatic sinusoidal injury

Palliative Venting Gastrostomy in Patients with Malignant Bowel Obstruction and Ascites ⬇️

Performance and prognostic utility of the 92-gene assay in the molecular subclassification of ampullary adenocarcinoma

Phase II study of capecitabine and oxaliplatin for advanced adenocarcinoma of the small bowel and ampulla of Vater.

Phase II trial of infusional fluorouracil, irinotecan, and bevacizumab for metastatic colorectal cancer: efficacy and circulating angiogenic biomarkers associated with therapeutic resistance

Portal hypertension associated with oxaliplatin administration: clinical manifestations of hepatic sinusoidal injury

Preoperative Therapy and Pancreatoduodenectomy for Pancreatic Ductal Adenocarcinoma: a 25-Year Single-Institution Experience

Progression-free survival remains poor over sequential lines of systemic therapy in patients with BRAF-mutated colorectal cancer

Recent advances in the management of adenocarcinoma of the small intestine.

Retrospective analysis of systemic chemotherapy and total parenteral nutrition for the treatment of malignant small bowel obstruction

Retrospective study of nonmucinous appendiceal adenocarcinomas: role of systemic chemotherapy and cytoreductive surgery

Second-line chemotherapy use in metastatic colon cancer varies by disease responsiveness.

Src activity is modulated by oxaliplatin and correlates with outcomes after hepatectomy for metastatic colorectal cancer.

Systematic survey of therapeutic trials for metastatic colorectal cancer: room for improvement in the critical pathway

Target-based therapeutic matching in early-phase clinical trials in patients with advanced colorectal cancer and PIK3CA mutations

The association of alternate VEGF ligands with resistance to anti-VEGF therapy in metastatic colorectal cancer

The expression of PTEN is associated with improved prognosis in patients with ampullary adenocarcinoma after pancreaticoduodenectomy

The impact of stage, grade, and mucinous histology on the efficacy of systemic chemotherapy in adenocarcinomas of the appendix: Analysis of the National Cancer Data Base

Worsening of thrombotic thromboctyopenic purpura symptoms associated with desmopressin administration