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List of works by Leo Heunks

Activation of the ubiquitin-proteasome pathway in the diaphragm in chronic obstructive pulmonary disease

scientific article published on 17 August 2006

Assembly 2: respiratory intensive care

scientific article

Assessment of dead-space ventilation in patients with acute respiratory distress syndrome: a prospective observational study.

scientific article published on 5 May 2016

Automated patient-ventilator interaction analysis during neurally adjusted non-invasive ventilation and pressure support ventilation in chronic obstructive pulmonary disease

scientific article

Bench-to-bedside review: Hypercapnic acidosis in lung injury - from 'permissive' to 'therapeutic'

scientific article published on November 3, 2010

Clinical review: The ABC of weaning failure - a structured approach

scientific article published on December 8, 2010

Clinical strategies for implementing lung and diaphragm-protective ventilation: avoiding insufficient and excessive effort

scientific article published on 02 November 2020

Correction to: Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study

scientific article published on 14 November 2017

Critical illness-associated diaphragm weakness

scientific article

Diaphragm Atrophy and Weakness in the Absence of Mitochondrial Dysfunction in the Critically Ill.

scientific article published on 8 August 2017

Diaphragm adaptations in patients with COPD.

scientific article published on 24 January 2008

Diaphragm dysfunction in chronic obstructive pulmonary disease.

scientific article published on 22 April 2005

Diaphragm fiber strength is reduced in critically ill patients and restored by a troponin activator.

scientific article published in April 2014

Diaphragm muscle fiber dysfunction in chronic obstructive pulmonary disease: toward a pathophysiological concept

scientific article published on 5 April 2007

Diaphragm muscle fiber weakness and ubiquitin-proteasome activation in critically ill patients

scientific article published on May 2015

Diaphragm single-fiber weakness and loss of myosin in congestive heart failure rats

scientific article published on 20 April 2007

EFFECTS OF EXPERIMENTAL HUMAN ENDOTOXEMIA ON DIAPHRAGM FUNCTION.

scientific article published on 18 July 2015

Effects of levosimendan on respiratory muscle function in patients weaning from mechanical ventilation

scientific article published on 01 October 2019

Effects of modulation of nitric oxide on rat diaphragm isotonic contractility during hypoxia

scientific article published on 18 October 2002

Efficacy of ventilator waveform observation for detection of patient-ventilator asynchrony during NIV: a multicentre study.

scientific article published on 4 October 2017

Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG SAFE prospective cohort study

scientific article published on 14 June 2017

How can you mend a broken heart?.

scientific article published in February 2012

Hypercapnia attenuates ventilator-induced diaphragm atrophy and modulates dysfunction.

scientific article

Hypoxia-induced dysfunction of rat diaphragm: role of peroxynitrite.

scientific article published on 10 September 2004

Hypoxia-induced skeletal muscle fiber dysfunction: role for reactive nitrogen species

scientific article

Impaired isotonic contractility and structural abnormalities in the diaphragm of congestive heart failure rats

scientific article published on 08 August 2007

Letter to the Editor.

scientific article published in August 2015

Levosimendan affects oxidative and inflammatory pathways in the diaphragm of ventilated endotoxemic mice

scientific article published on 2 March 2015

Levosimendan beyond inotropy and acute heart failure: Evidence of pleiotropic effects on the heart and other organs: An expert panel position paper

scientific article

Levosimendan enhances force generation of diaphragm muscle from patients with chronic obstructive pulmonary disease

scientific article

Low-tidal-volume mechanical ventilation induces a toll-like receptor 4-dependent inflammatory response in healthy mice

scientific article published on September 2008

Lung ultrasound findings in patients with novel SARS-CoV2

scientific article published on 21 May 2020

Mechanical ventilation induces a Toll/interleukin-1 receptor domain-containing adapter-inducing interferon beta-dependent inflammatory response in healthy mice

scientific article published on 01 October 2009

Monitoring and preventing diaphragm injury.

scientific article published on February 2015

Monitoring of the Respiratory Muscles in the Critically Ill

scientific article published on October 26, 2012

Nitric oxide modulates neuromuscular transmission during hypoxia in rat diaphragm.

scientific article

Non-invasive mechanical ventilation for diagnostic bronchoscopy using a new face mask: an observational feasibility study

scientific article

Noninvasive ventilation and the upper airway: should we pay more attention?

scientific article published on 05 December 2013

Novel insights in ICU-acquired respiratory muscle dysfunction: implications for clinical care

scientific article published on 21 March 2017

Oxidative and nitrosative stress in the diaphragm of patients with COPD.

scientific article published on January 2006

Oxygen-induced hypercapnia in COPD: myths and facts

scientific article published on October 29, 2012

Partial Neuromuscular Blockade during Partial Ventilatory Support in Sedated Patients with High Tidal Volumes

scientific article published on 17 October 2016

Plasma from septic shock patients induces loss of muscle protein.

scientific article published on 29 September 2011

Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study.

scientific article published on 18 October 2016

Proteasome inhibition improves diaphragm function in an animal model for COPD.

scientific article published in April 2011

Proteasome inhibition improves diaphragm function in congestive heart failure rats

scientific article

Recruitment pattern of the diaphragm and extradiaphragmatic inspiratory muscles in response to different levels of pressure support

scientific article published on 29 May 2020

Respiratory Muscle Effort during Expiration in Successful and Failed Weaning from Mechanical Ventilation

scientific article published on 01 September 2018

Respiratory muscle ultrasonography: methodology, basic and advanced principles and clinical applications in ICU and ED patients-a narrative review

scientific article published on 14 January 2020

Strategies to optimize respiratory muscle function in ICU patients

scientific article

Supplemental oxygen prevents exercise-induced oxidative stress in muscle-wasted patients with chronic obstructive pulmonary disease

scientific article published on 02 March 2006

The calcium sensitizer levosimendan improves human diaphragm function

scientific article published on 01 January 2012

The differential diagnosis for failure to wean from mechanical ventilation.

scientific article published on 5 February 2016

The impact of critical illness on the expiratory muscles and the diaphragm assessed by ultrasound in mechanical ventilated children

scientific article published on 27 August 2020

The role of calpains in ventilator-induced diaphragm atrophy

scientific article published on 14 March 2017

The role of poly (ADP-ribose) polymerase in ventilator-induced lung injury

scientific article published on 22 October 2008

Time course of diaphragm function recovery after controlled mechanical ventilation in rats

scientific article published on July 11, 2013

Titin and diaphragm dysfunction in chronic obstructive pulmonary disease

scientific article published on 09 December 2005

Titin and diaphragm dysfunction in mechanically ventilated rats

scientific article published on February 11, 2012

Titin-based mechanosensing and signaling: role in diaphragm atrophy during unloading?

scientific article published on November 12, 2010

Toll-like receptor 4 signaling in ventilator-induced diaphragm atrophy

scientific article published on 01 August 2012

Ultrasound to assess diaphragmatic function in the critically ill-a critical perspective

scientific article published on March 2017