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List of works by Nader G Abraham

11,12-epoxyeicosatrienoic acid stimulates heme-oxygenase-1 in endothelial cells

scientific article published on 30 August 2006

12(R)-hydroxyeicosatrienoic acid: a vasodilator cytochrome P-450-dependent arachidonate metabolite from the bovine corneal epithelium

scientific article published on 01 November 1988

12(R)-hydroxyicosatetraenoic acid: a cytochrome-P450-dependent arachidonate metabolite that inhibits Na+,K+-ATPase in the cornea

scientific article

A closed eye contact lens model of corneal inflammation. Part 1: Increased synthesis of cytochrome P450 arachidonic acid metabolites

article

A closed eye contact lens model of corneal inflammation. Part 2: Inhibition of cytochrome P450 arachidonic acid metabolism alleviates inflammatory sequelae

article

A significant role for the heme oxygenase-1 gene in endothelial cell cycle progression

scientific article published in February 2002

Ablation of adipose-HO-1 expression increases white fat over beige fat through inhibition of mitochondrial fusion and of PGC1α in female mice

scientific article

Ablation of soluble epoxide hydrolase reprogram white fat to beige-like fat through an increase in mitochondrial integrity, HO-1-adiponectin in vitro and in vivo

scientific article published on 21 July 2018

Activation of nuclear factor kappa B and oncogene expression by 12(R)-hydroxyeicosatrienoic acid, an angiogenic factor in microvessel endothelial cells ⬇️

scientific article published on September 30, 1994

Additive effect of erythropoietin and heme on murine hematopoietic recovery after azidothymidine treatment.

scientific article

Adenoviral vector-mediated transfer of human heme oxygenase in rats decreases renal heme-dependent arachidonic acid epoxygenase activity

Adenovirus-mediated heme oxygenase-1 gene transfer into rabbit ocular tissues

scientific article published on 01 October 1995

Adipocyte Specific HO-1 Gene Therapy is Effective in Antioxidant Treatment of Insulin Resistance and Vascular Function in an Obese Mice Model

scientific article published on 01 January 2020

Adipocyte heme oxygenase-1 induction attenuates metabolic syndrome in both male and female obese mice

scientific article

Adiponectin is associated with abnormal lipid profile and coronary microvascular dysfunction in patients with dilated cardiomyopathy without overt heart failure

scientific article published on 04 March 2010

Age-related changes in renal cytochrome P-450 arachidonic acid metabolism in spontaneously hypertensive rats ⬇️

scientific article published on 01 January 1992

Agonists of epoxyeicosatrienoic acids reduce infarct size and ameliorate cardiac dysfunction via activation of HO-1 and Wnt1 canonical pathway.

scientific article published on January 2015

Allogeneic intra-bone marrow transplantation prevents rheumatoid arthritis in SKG/Jcl mice

scientific article published on 5 April 2009

Amelioration of cognitive ability in senescence-accelerated mouse prone 8 (SAMP8) by intra-bone marrow-bone marrow transplantation

scientific article published on 5 September 2009

Angiotensin II induces carbon monoxide production in the perfused kidney: relationship to protein kinase C activation

scientific article published on 13 July 2004

Antioxidant mechanism of heme oxygenase-1 involves an increase in superoxide dismutase and catalase in experimental diabetes

scientific article published on 8 April 2005

Antioxidants condition pleiotropic vascular responses to exogenous H(2)O(2): role of modulation of vascular TP receptors and the heme oxygenase system

scientific article published on 28 September 2012

Antiproliferative effect of oleuropein in prostate cell lines.

scientific article

Apo A1 Mimetic Rescues the Diabetic Phenotype of HO-2 Knockout Mice via an Increase in HO-1 Adiponectin and LKBI Signaling Pathway ⬇️

scientific article published on April 4, 2012

ApoA1: mimetic peptide reverses adipocyte dysfunction in vivo and in vitro via an increase in heme oxygenase (HO-1) and Wnt10b.

scientific article published on 15 February 2012

Apoptotic markers in a prostate cancer cell line: effect of ellagic acid

scientific article published on 30 September 2013

Arachidonic acid omega-hydroxylation and cytochrome P450 4A expression in the rat kidney

scientific article published on 01 January 1995

Attenuation of Na/K-ATPase Mediated Oxidant Amplification with pNaKtide Ameliorates Experimental Uremic Cardiomyopathy

scientific article published on 04 October 2016

Author Correction: The Adipocyte Na/K-ATPase Oxidant Amplification Loop is the Central Regulator of Western Diet-Induced Obesity and Associated Comorbidities

scientific article published on 05 November 2020

Beneficial Role of HO-1-SIRT1 Axis in Attenuating Angiotensin II-Induced Adipocyte Dysfunction

scientific article published on 29 June 2019

Beneficial effect of heme oxygenase-1 expression on myocardial ischemia-reperfusion involves an increase in adiponectin in mildly diabetic rats

scientific article published on 28 September 2007

Benzene modulation of liver cell structure and heme-cytochrome P-450 metabolism

scientific article

Bone marrow stem cell transplant into intra-bone cavity prevents type 2 diabetes: role of heme oxygenase-adiponectin.

scientific article

CD163-Mediated hemoglobin-heme uptake activates macrophage HO-1, providing an antiinflammatory function

scientific article published on 01 October 2006

CO modulates pulmonary vascular response to acute hypoxia: relation to endothelin

scientific article published on 11 September 2003

COX-2 lack of function in hypoxia-induced ocular surface inflammation ⬇️

scientific article published on June 15, 2003

CYP-450 Epoxygenase Derived Epoxyeicosatrienoic Acid Contribute To Reversal of Heart Failure in Obesity-Induced Diabetic Cardiomyopathy via PGC-1 α Activation.

scientific article published on 8 February 2018

CYP2J2 targeting to endothelial cells attenuates adiposity and vascular dysfunction in mice fed a high-fat diet by reprogramming adipocyte phenotype.

scientific article

CYP4A2-induced hypertension is 20-hydroxyeicosatetraenoic acid- and angiotensin II-dependent

scientific article

Caloric restriction ameliorates cardiomyopathy in animal model of diabetes

scientific article published on 21 November 2016

Can charcoal improve outcomes in COVID-19 infections?

scientific article published on 10 August 2020

Carbon monoxide and biliverdin prevent endothelial cell sloughing in rats with type I diabetes

scientific article published on 20 March 2006

Carbon monoxide signaling in promoting angiogenesis in human microvessel endothelial cells

scientific article published on 01 May 2005

Cardioprotective Heme Oxygenase-1-PGC1α Signaling in Epicardial Fat Attenuates Cardiovascular Risk in Humans as in Obese Mice

scientific article published on 23 August 2019

Central Role for Adipocyte Na,K-ATPase Oxidant Amplification Loop in the Pathogenesis of Experimental Uremic Cardiomyopathy

scientific article published on 25 June 2020

Change in renal heme oxygenase expression in cyclosporine A-induced injury

scientific article published in January 2005

Characterization of a 142-bp fragment of the murine c-fos oncogene promoter upstream of the SIF-binding element

scientific article published on May 1994

Characterization of a murine model of cardiorenal syndrome type 1 by high-resolution Doppler sonography.

scientific article published on 20 September 2014

Characterization of human liver and kidney cytochrome P-450-dependent arachidonic acid epoxygenase

Chronic CO levels have [corrected] a beneficial effect on vascular relaxation in diabetes

scientific article published on 27 December 2005

Circulating endothelial cells are elevated in patients with type 2 diabetes mellitus independently of HbA(1)c

scientific article published on 20 January 2005

Co-regulation of heme oxygenase and erythropoietin genes

article

Cobalt-Protoporphyrin Improves Heart Function by Blunting Oxidative Stress and Restoring NO Synthase Equilibrium in an Animal Model of Experimental Diabetes

scientific article

Coexpression of erythropoietin and heme oxygenase genes in Hep3B cells

scientific article published on 01 May 1993

Cold Press Pomegranate Seed Oil Attenuates Dietary-Obesity Induced Hepatic Steatosis and Fibrosis through Antioxidant and Mitochondrial Pathways in Obese Mice

scientific article published on 31 July 2020

Cold-Pressed Nigella Sativa Oil Standardized to 3% Thymoquinone Potentiates Omega-3 Protection against Obesity-Induced Oxidative Stress, Inflammation, and Markers of Insulin Resistance Accompanied with Conversion of White to Beige Fat in Mice

scientific article published on 04 June 2020

Comparative Effect of Heme Analogues on Hematopoiesis in Lymphoproliferative Disorders ⬇️

scientific article published on 01 January 1991

Comparative effects of heme and metalloporphyrins on interferon-gamma-mediated pathways in monocytic cells (THP-1).

scientific article published on April 1993

Comparative pharmacology of zinc mesoporphyrin and tin mesoporphyrin: toxic actions of zinc mesoporphyrin on hematopoiesis and progenitor cell mobilization

scientific article published on 01 January 1999

Comparison of Hemin Enhancement of Burst-Forming Units-Erythroid Clonal Efficiency by Progenitor Cells from Normal and HIV-Infected Patients ⬇️

scientific article published on 01 January 1991

Corneal arachidonate metabolism via cytochrome P450: characterization of two novel biologically active metabolites

scientific article published on 01 January 1989

Correction to: Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving 'SIRT1 and PGC-1α'

scholarly article published in Cardiovascular Diabetology

Corrigendum to “Chronic CO levels have a beneficial effect on vascular relaxation in diabetes” [Biochem. Biophys. Res. Commun. 340 (2005) 935–943]

scholarly article published in Biochemical and Biophysical Research Communications

Corrigendum: Attenuation of Na/K-ATPase Mediated Oxidant Amplification with pNaKtide Ameliorates Experimental Uremic Cardiomyopathy

scientific article published on 20 October 2017

Crosstalk between EET and HO-1 downregulates Bach1 and adipogenic marker expression in mesenchymal stem cell derived adipocytes.

scientific article

Cyclooxygenase Activity is Regulated by the Heme Oxygenase System in Microvessel Endothelial Cells ⬇️

scientific article published on 01 January 2003

Cyclooxygenase-2 dependent metabolism of 20-HETE increases adiposity and adipocyte enlargement in mesenchymal stem cell-derived adipocytes ⬇️

scientific article published on January 4, 2013

Cytochrome P450 dependent metabolism of arachidonic acid in bovine corneal epithelium

scientific article published on 01 October 1985

Cytochrome P450, drug metabolizing enzymes and arachidonic acid metabolism in bovine ocular tissues

scientific article published on 01 April 1987

Cytochrome P450-dependent arachidonate metabolism in corneal epithelium: formation of biologically active compounds

scientific article published on 01 January 1987

Cytochrome P450-dependent arachidonic acid metabolism in human kidney

scientific article published in January 1990

D-4F induces heme oxygenase-1 and extracellular superoxide dismutase, decreases endothelial cell sloughing, and improves vascular reactivity in rat model of diabetes

scientific article published on 6 June 2005

Development of NASH in Obese Mice is Confounded by Adipose Tissue Increase in Inflammatory NOV and Oxidative Stress

article

Development of a cytochrome P-450 monooxygenase system in clonogenic hemopoietic cells

scientific article published on 01 April 1987

Diabetes impairs the vascular recruitment of normal stem cells by oxidant damage, reversed by increases in pAMPK, heme oxygenase-1, and adiponectin

scientific article published on February 2009

Differential effect of cobalt protoporphyrin on distributions of heme oxygenase in renal structure and on blood pressure in SHR.

scientific article published in December 2002

Differential effect of heme oxygenase-1 in endothelial and smooth muscle cell cycle progression

scientific article published on 01 September 2002

Differential effects of heme oxygenase isoforms on heme mediation of endothelial intracellular adhesion molecule 1 expression

scientific article published on 01 October 1999

Differential effects of partial hepatectomy on hepatic and renal heme and cytochrome P450 metabolism

scientific article published on 01 December 1988

Differential heme oxygenase induction by stannous and stannic ions in the heart

scientific article published on 01 March 1995

Differential induction of heme oxygenase in the hepatocarcinoma cell line (Hep3B) by environmental agents

scientific article published on July 1, 1992

Diminished Heme Oxygenase Potentiates Cell Death: Pyrrolidinedithiocarbamate Mediates Oxidative Stress ⬇️

scientific article published on May 1, 2003

Diminished heme oxygenase-1 mRNA expression in RPE cells from diabetic donors as quantitated by competitive RT/PCR

scientific article published on 01 April 1997

Direct stimulation of limbal microvessel endothelial cell proliferation and capillary formation in vitro by a corneal-derived eicosanoid

scientific article published on January 1996

Downregulation of PGC-1α Prevents the Beneficial Effect of EET-Heme Oxygenase-1 on Mitochondrial Integrity and Associated Metabolic Function in Obese Mice

scientific article published on 20 December 2016

Downregulation of the human heme oxygenase gene by glucocorticoids and identification of 56b regulatory elements

scientific article published in January 1996

Dual role of heme oxygenase in epithelial cell injury: contrasting effects of short-term and long-term exposure to oxidant stress

scientific article published on September 1996

Dysglycemia induces abnormal circadian blood pressure variability ⬇️

scientific article published on November 22, 2011

EET agonist prevents adiposity and vascular dysfunction in rats fed a high fat diet via a decrease in Bach 1 and an increase in HO-1 levels

scientific article published on 24 December 2011

EET enhances renal function in obese mice resulting in restoration of HO-1-Mfn1/2 signaling, and decrease in hypertension through inhibition of sodium chloride co-transporter

scientific article published on 19 May 2018

EET intervention on Wnt1, NOV, and HO-1 signaling prevents obesity-induced cardiomyopathy in obese mice.

scientific article published on 2 June 2017

Eclectic mechanisms of heme regulation of hematopoiesis

scientific article published on May 1991

Effect of acute and chronic treatment of tin on blood pressure in spontaneously hypertensive rats.

scientific article published in January 1992

Effect of age on rat liver heme and drug metabolism

scientific article published on January 1985

Effect of heme arginate administration on blood pressure in spontaneously hypertensive rats

scientific article

Effects of Heme Oxygenase-1 Upregulation on Blood Pressure and Cardiac Function in an Animal Model of Hypertensive Myocardial Infarction ⬇️

scientific article published on January 28, 2013

Effects of ellagic Acid on angiogenic factors in prostate cancer cells

scientific article published on 19 June 2013

Effects of iron deficiency and chronic iron overloading on mitochondrial heme biosynthetic enzymes in rat liver

scientific journal article

Elevated level of pro-inflammatory eicosanoids and EPC dysfunction in diabetic patients with cardiac ischemia ⬇️

scientific article published on January 3, 2013

Elevated levels of heme oxygenase-1 activity and mRNA in peripheral blood adherent cells of acquired immunodeficiency syndrome patients

scientific article

Ellagic acid: cytodifferentiating and antiproliferative effects in human prostatic cancer cell lines.

scientific article

Endothelial dysfunction and hypertension in rats transduced with CYP4A2 adenovirus

scientific article

Endothelial progenitor cell function inversely correlates with long-term glucose control in diabetic patients: association with the attenuation of the heme oxygenase-adiponectin axis

scientific article published on 23 March 2012

Endothelial-specific CYP4A2 overexpression leads to renal injury and hypertension via increased production of 20-HETE. ⬇️

scientific article published on 12 August 2009

Epoxyeicosatrienoic Acid as Therapy for Diabetic and Ischemic Cardiomyopathy

scientific article published on 12 September 2016

Epoxyeicosatrienoic Acids Regulate Adipocyte Differentiation of Mouse 3T3 Cells, Via PGC-1α Activation, Which Is Required for HO-1 Expression and Increased Mitochondrial Function

scientific article published on 25 May 2016

Epoxyeicosatrienoic acid agonist regulates human mesenchymal stem cell-derived adipocytes through activation of HO-1-pAKT signaling and a decrease in PPARγ

scientific article

Epoxyeicosatrienoic acid agonist rescues the metabolic syndrome phenotype of HO-2-null mice

scientific article

Epoxyeicosatrienoic acids and heme oxygenase-1 interaction attenuates diabetes and metabolic syndrome complications ⬇️

scientific article published on November 15, 2011

Epoxyeicosatrienoic intervention improves NAFLD in leptin receptor deficient mice by an increase in PGC1α-HO-1-PGC1α-mitochondrial signaling

scientific article published on 27 April 2019

Erythroid colony development as a function of age: the role of marrow cellular heme

scientific article published on 01 January 1983

Erythropoietin controls heme metabolic enzymes in normal human bone marrow culture

scientific article published on 01 September 1989

Existence of a Strong Correlation of Biomarkers and miRNA in Females with Metabolic Syndrome and Obesity in a Population of West Virginia

scientific article

Expression of Heme Oxygenase-1 in Thick Ascending Loop of Henle Attenuates Angiotensin II-Dependent Hypertension ⬇️

scientific article published on February 9, 2012

Expression of heme oxygenase gene in rat and human liver

scientific article published in January 1988

Expression of heme oxygenase in hemopoiesis.

scientific article

Expression of human heme oxygenase-1 in the thick ascending limb attenuates angiotensin II-mediated increase in oxidative injury

scientific article published in May 2004

Formation of biologically active cytochrome P450-arachidonate metabolites in renomedullary cells

scientific article published on 01 January 1987

Functional Expression of Human Heme Oxygenase-1 Gene in Renal Structure of Spontaneously Hypertensive Rats ⬇️

scientific article published on May 1, 2003

Functional expression of human heme oxygenase-1 (HO-1) driven by HO-1 promoter in vitro and in vivo

scientific article

Genetic Polymorphisms Complicate COVID-19 Therapy: Pivotal Role of HO-1 in Cytokine Storm

scientific article published on 18 July 2020

Genetic suppression of HO-1 exacerbates renal damage: reversed by an increase in the antiapoptotic signaling pathway

scientific article published on 29 August 2006

HO-1 Induction Improves The Type-1 Cardiorenal Syndrome in Mice With Impaired Angiotensin II–Induced Lymphocyte Activation ⬇️

scientific article published on June 10, 2013

HO-1 Upregulation Attenuates Adipocyte Dysfunction, Obesity, and Isoprostane Levels in Mice Fed High Fructose Diets

scientific article

HO-1 expression increases mesenchymal stem cell-derived osteoblasts but decreases adipocyte lineage

scientific article

HO-1 overexpression and underexpression: Clinical implications

scientific article published on 16 August 2019

Heme Oxygenase Attenuates Angiotensin II-Mediated Increase in Cyclooxygenase-2 Activity in Human Femoral Endothelial Cells

scientific article published on 30 December 2002

Heme Oxygenase-1 Gene Expression Attenuates Angiotensin II-Mediated DNA Damage in Endothelial Cells ⬇️

scientific article published on May 1, 2003

Heme Oxygenase-1 Upregulation: A Novel Approach in the Treatment of Cardiovascular Disease

scientific article published on 10 February 2020

Heme induced oxidative stress attenuates sirtuin1 and enhances adipogenesis in mesenchymal stem cells and mouse pre-adipocytes

scientific article

Heme inhibits human immunodeficiency virus 1 replication in cell cultures and enhances the antiviral effect of zidovudine

scientific article (publication date: March 1991)

Heme metabolism and erythropoiesis in abnormal iron states: role of delta-aminolevulinic acid synthase and heme oxygenase

scientific article published on 01 September 1985

Heme metabolism and in vitro erythropoiesis in anemia associated with hypochromic microcytosis

scientific article published on 01 January 1988

Heme metabolism in erythroid and hepatic cells

scientific article published on January 1, 1983

Heme oxygenase (HO-1) rescue of adipocyte dysfunction in HO-2 deficient mice via recruitment of epoxyeicosatrienoic acids (EETs) and adiponectin

scientific article published on March 2012

Heme oxygenase -1 gene therapy: recent advances and therapeutic applications

scientific article published on April 2007

Heme oxygenase and the cardiovascular-renal system

scientific article

Heme oxygenase gene targeting to adipocytes attenuates adiposity and vascular dysfunction in mice fed a high-fat diet

scientific article

Heme oxygenase induction with attenuation of experimentally induced corneal inflammation

scientific article published on April 1997

Heme oxygenase overexpression attenuates glucose-mediated oxidative stress in quiescent cell phase: linking heme to hyperglycemia complications.

scientific article published in April 2005

Heme oxygenase-1 accelerates tumor angiogenesis of human pancreatic cancer

scientific article published on January 1, 2003

Heme oxygenase-1 attenuates glucose-mediated cell growth arrest and apoptosis in human microvessel endothelial cells

scientific article published on 21 August 2003

Heme oxygenase-1 enhances renal mitochondrial transport carriers and cytochrome C oxidase activity in experimental diabetes

scientific article published on 04 April 2006

Heme oxygenase-1 gene expression modulates angiotensin II-induced increase in blood pressure

scientific article

Heme oxygenase-1 induction improves cardiac function following myocardial ischemia by reducing oxidative stress

scientific article

Heme oxygenase-1 induction modulates hypoxic pulmonary vasoconstriction through upregulation of ecSOD.

scientific article published on 07 August 2009

Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats

scientific article published on 26 January 2009

Heme oxygenase-1 inhibition of Nox oxidase activation is a microvascular endothelial antioxidant effect of NO

scientific article published on 18 September 2006

Heme oxygenase-1 modulates fetal growth in the rat.

scientific article

Heme oxygenase-1 prevents superoxide anion-associated endothelial cell sloughing in diabetic rats

scientific article published in March 2004

Heme oxygenase-1 protects against radiocontrast-induced acute kidney injury by regulating anti-apoptotic proteins

scientific article published on 01 August 2007

Heme oxygenase-2 deficiency contributes to diabetes-mediated increase in superoxide anion and renal dysfunction

scientific article published on 8 March 2006

Heme oxygenase-2 deletion impairs macrophage function: implication in wound healing

scientific article

Heme oxygenase-2 is a critical determinant for execution of an acute inflammatory and reparative response

scientific article published on November 2006

Heme oxygenase-2/adiponectin protein-protein interaction in metabolic syndrome.

scientific article published on 21 February 2013

Heme oxygenase-derived carbon monoxide restores vascular function in type 1 diabetes

scientific article

Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells

scientific article published on 11 March 2008

Heme oxygenase: a target gene for anti-diabetic and obesity

scientific article published on January 2008

Heme oxygenase: the key to renal function regulation

scientific article published on July 2009

Hemin and L-arginine regulation of blood pressure in spontaneous hypertensive rats ⬇️

scientific article published on December 1, 1991

Hemin stimulation of hemopoiesis in murine long-term bone marrow culture

scientific article published on October 1, 1991

High fat diet enhances cardiac abnormalities in SHR rats: Protective role of heme oxygenase-adiponectin axis ⬇️

scientific article published on December 23, 2011

High-fat diet-induced obesity and insulin resistance in CYP4a14-/- mice is mediated by 20-HETE

scientific article published on 08 August 2018

High‐Fat Diet Exacerbates Renal Dysfunction in SHR: Reversal by Induction of HO‐1–Adiponectin Axis ⬇️

scientific article published on December 22, 2011

Human heme oxygenase-1 gene transfer lowers blood pressure and promotes growth in spontaneously hypertensive rats

scientific article

Human heme oxygenase: cell cycle-dependent expression and DNA microarray identification of multiple gene responses after transduction of endothelial cells.

scientific article published in December 2003

Identification and purification of mesodermal progenitor cells from human adult bone marrow.

scientific article published on July 2009

Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 gene

scientific article published on June 1994

Identification of heme oxygenase and cytochrome P-450 in the rabbit heart

scientific article published on 01 January 1987

Immunochemical studies on the contribution of NADPH cytochrome P-450 reductase to the cytochrome P-450-dependent metabolism of arachidonic acid

scientific article published on 01 February 1987

Immunocytochemical localization and expression of heme oxygenase-1 in primary astroglial cell cultures during differentiation: effect of glutamate

scientific journal article

Impact of silencing HO-2 on EC-SOD and the mitochondrial signaling pathway

scientific article

Improved Expression of Sirt1 on Thymic Epithelial Cells of SAMP10 after Intrabone Marrow–Bone Marrow Transplantation ⬇️

scientific article published on February 26, 2013

Improved myocardial perfusion in chronic diabetic mice by the up-regulation of pLKB1 and AMPK signaling.

scientific article published on April 2010

Increase in heme oxygenase-1 levels ameliorates renovascular hypertension

scientific article published in December 2005

Increased HO-1 levels ameliorate fatty liver development through a reduction of heme and recruitment of FGF21.

scientific article published on 02 December 2013

Increased heme-oxygenase 1 expression in mesenchymal stem cell-derived adipocytes decreases differentiation and lipid accumulation via upregulation of the canonical Wnt signaling cascade.

scientific article published on 12 March 2013

Induction of heme oxygenase-1 in renovascular hypertension is associated with inhibition of apoptosis

scientific article published on 15 May 2007

Influence of Heme and Heme Oxygenase-1 Transfection of Pulmonary Microvascular Endothelium on Oxidant Generation and cGMP ⬇️

scientific article published on May 1, 2003

Inhibition of erythropoiesis in chronic renal failure: the role of parathyroid hormone

scientific article published on 01 March 1984

Inhibition of human adult and fetal heme oxygenase by new synthetic heme analogues

scientific article published on 01 September 1988

Inhibition of human immunodeficiency virus-1 reverse transcriptase by heme and synthetic heme analogs

scientific article published on January 1996

Interdiction of the diabetic state in NOD mice by sustained induction of heme oxygenase: possible role of carbon monoxide and bilirubin

scientific article published on 01 July 2007

Involvement of reactive oxygen species in a feed-forward mechanism of Na/K-ATPase-mediated signaling transduction

scientific article published on 11 October 2013

Isolation and purification of erythropoiesis inhibitory activity from uremic sera

scientific article published on 01 January 1988

Kavain Reduces Porphyromonas gingivalis-Induced Adipocyte Inflammation: Role of PGC-1α Signaling

scientific article published on 23 July 2018

Kinetic properties of the membrane-bound human liver mitochondrial protoporphyrinogen oxidase

article by Jean-Michel Camadro et al published 1 October 1985 in Archives of Biochemistry and Biophysics

Kinetic studies of human liver ferrochelatase. Role of endogenous metals

scientific article published on 01 May 1984

L-4F treatment reduces adiposity, increases adiponectin levels, and improves insulin sensitivity in obese mice

scientific article published on 19 April 2008

Lentiviral-human heme oxygenase targeting endothelium improved vascular function in angiotensin II animal model of hypertension

scientific article

Localization of erythropoietin mRNA in the rat kidney by polymerase chain reaction

scientific article published on 01 February 1994

Long-Term Treatment with the Apolipoprotein A1 Mimetic Peptide Increases Antioxidants and Vascular Repair in Type I Diabetic Rats

scientific article published on 08 May 2007

Long-lasting expression of HO-1 delays progression of type I diabetes in NOD mice

scientific article published on 29 March 2007

Long-term bone marrow stromal and hemopoietic toxicity to AZT: protective role of heme and IL-1

scientific article published on February 1, 1993

Long-term effects of heme oxygenase 1 overexpression on post-infarction heart function in diabetic rats

scientific article published on September 2014

Manipulation of cytochrome P-450 dependent renal thromboxane synthase activity in spontaneously hypertensive rats

scientific article published on 01 January 1989

Mechanism of Heme-Heme Oxygenase System Impairment of Endothelium Contraction in the Spontaneously Hypertensive Rat ⬇️

scientific article published on September 26, 2011

Methods for measurements of heme oxygenase (HO) isoforms-mediated synthesis of carbon monoxide and HO-1 and HO-2 proteins

scientific article published on 01 January 2003

Microenvironmental cytokines and expression of erythroid heme metabolic enzymes

scientific article published on 01 January 1987

Microenvironmental toxicity of azidothymidine: partial sparing with hemin

scientific article published on 01 July 1989

Milk thistle seed cold press oil attenuates markers of the metabolic syndrome in a mouse model of dietary-induced obesity

scientific article published on 12 October 2020

Modulation of cGMP by human HO-1 retrovirus gene transfer in pulmonary microvessel endothelial cells

scientific article

Modulation of corneal heme oxygenase expression by oxidative stress agents

scientific article published on January 1995

Modulation of erythropoiesis by novel human bone marrow cytochrome P450-dependent metabolites of arachidonic acid

scientific article published on 01 September 1991

Negative regulation of human heme oxygenase in microvessel endothelial cells by dexamethasone

scientific article published on 01 November 1999

Novel regulatory sites of the human heme oxygenase-1 promoter region

scientific article published on 01 October 1993

OX-HDL: A Starring Role in Cardiorenal Syndrome and the Effects of Heme Oxygenase-1 Intervention

scientific article published on 20 November 2020

Overexpression of heme oxygenase-1 increases human osteoblast stem cell differentiation.

scientific article

Overexpression of human heme oxygenase-1 attenuates endothelial cell sloughing in experimental diabetes

scientific article

Overexpression of the heme oxygenase gene in renal cell carcinoma

scientific article published on 01 January 1997

Oxidant-Induced Alterations in the Adipocyte Transcriptome: Role of the Na,K-ATPase Oxidant Amplification Loop

scientific article published on 18 August 2020

Oxidative Stress and Heme Oxygenase-1 Regulated Human Mesenchymal Stem Cells Differentiation ⬇️

scientific article published on February 26, 2012

Oxidized HDL and Isoprostane Exert a Potent Adipogenic Effect on Stem Cells: Where in the Lineage?

scientific article published on 27 April 2016

Oxidized HDL is a potent inducer of adipogenesis and causes activation of the Ang-II and 20-HETE systems in human obese females

scientific article published on 11 May 2016

Oxidized HDL, Adipokines, and Endothelial Dysfunction: A Potential Biomarker Profile for Cardiovascular Risk in Women with Obesity

scientific article published on 01 January 2019

PARP-1 inhibition protects the diabetic heart through activation of SIRT1-PGC-1α axis

scientific article published on 23 October 2018

PGC-1 alpha regulates HO-1 expression, mitochondrial dynamics and biogenesis: Role of epoxyeicosatrienoic acid

scientific article published on 11 July 2016

Pharmacologic effects of the red blood cell substitutes cross-linked and non-cross-linked hemoglobins on hematopoiesis in rabbits

scientific article published on 01 June 1999

Pharmacologic toxicity of cimetidine on hepatic and renal drug metabolism.

scientific article published on July 1984

Pharmacological and clinical aspects of heme oxygenase

scientific article

Physiologic role of heme and cytochrome P-450 in hematopoietic cells

scientific article published on March 1991

Physiological significance of heme oxygenase in hypertension

scientific article

Positive Effects of Heme Oxygenase Upregulation on Adiposity and Vascular Dysfunction: Gene Targeting vs. Pharmacologic Therapy.

scientific article published on 22 May 2019

Presence of cytochrome P-450-dependent monooxygenase in intimal cells of the hog aorta

scientific article published in November 1985

Presence of heme oxygenase and NADPH cytochrome P-450 (c) reductase in human corneal epithelium

scientific article published on 01 September 1987

Prevention of premature ovarian failure and osteoporosis induced by irradiation using allogeneic ovarian/bone marrow transplantation

scientific article published in February 2010

Properties of human kidney heme oxygenase: inhibition by synthetic heme analogues and metalloporphyrins

scientific article published on 01 December 1988

Protective effect of HO-1 against oxidative stress in human hepatoma cell line (HepG2) is independent of telomerase enzyme activity

scientific article published on December 2002

Protoporphyrin IX generation from delta-aminolevulinic acid elicits pulmonary artery relaxation and soluble guanylate cyclase activation

scientific article published on 01 September 2006

Purification and characterization of cytochrome P-450-dependent arachidonic acid epoxygenase from human liver

scientific article published on 01 February 1988

Quantitation of Human Heme Oxygenase (HO‐1) Copies by Competitive RT‐PCR ⬇️

scientific article published on 01 January 2002

Quantitative measurement of heme oxygenase-1 in the human renal adenocarcinoma.

scientific article

RETRACTED ARTICLE: The Adipocyte Na/K-ATPase Oxidant Amplification Loop is the Central Regulator of Western Diet-Induced Obesity and Associated Comorbidities

retracted scholarly article

Rat mesenteric arterial dilator response to 11,12-epoxyeicosatrienoic acid is mediated by activating heme oxygenase

scientific article published on 23 June 2006

Reciprocal Effects of Oxidative Stress on Heme Oxygenase Expression and Activity Contributes to Reno-Vascular Abnormalities in EC-SOD Knockout Mice ⬇️

scientific article published on January 12, 2012

Regulation of Cyclooxygenase by the Heme-Heme Oxygenase System in Microvessel Endothelial Cells ⬇️

scientific article published on January 1, 2002

Regulation of arachidonic acid metabolism by cytochrome P-450 in rabbit kidney

scientific article published on August 1986

Regulation of cyclooxygenase- and cytochrome p450-derived eicosanoids by heme oxygenase in the rat kidney

scientific article published in February 2002

Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving 'SIRT1 and PGC-1α'

Regulation of human heme oxygenase in endothelial cells by using sense and antisense retroviral constructs

scientific article

Relationship between dietary sodium and sugar intake: A cross-sectional study of the National Health and Nutrition Examination Survey 2001-2016

scientific article published on 06 August 2020

Renal cytochrome P-450-arachidonic acid metabolism: localization and hormonal regulation in SHR

scientific article published on 01 April 1992

Renal cytochrome P-450-dependent metabolism of arachidonic acid in cirrhotic rats

scientific article published on 01 March 1991

Renal cytochrome P450-dependent oxygenation of arachidonic acid

scientific article published on 01 January 1987

Retracted: Fructose Mediated Non-Alcoholic Fatty Liver Is Attenuated by HO-1-SIRT1 Module in Murine Hepatocytes and Mice Fed a High Fructose Diet

retracted article

Retrovirus-mediated HO gene transfer into endothelial cells protects against oxidant-induced injury

scientific article published in July 1999

Role of heme metabolism in AZT-induced bone marrow toxicity

scientific article published on 01 September 1990

Role of heme oxygenase in heme-mediated inhibition of rat brain Na+-K+-ATPase: protection by tin-protoporphyrin

scientific article published on 01 September 1989

Role of human heme oxygenase-1 in attenuating TNF-alpha-mediated inflammation injury in endothelial cells

scientific article published in January 2002

Role of the heme oxygenases in abnormalities of the mesenteric circulation in cirrhotic rats.

scientific article published on 4 November 2003

Roles of renal cytochrome P450-dependent arachidonic acid metabolites in hypertension

scientific article published on January 1, 1992

Sensitivity of human tissue heme oxygenase to a new synthetic metalloporphyrin

scientific article published on 01 September 1989

Sideroblastic anemia: differences in bone marrow erythroid colony (CFUE) growth responses to erythropoietin in plasma clot and methylcellulose cultures

scientific article published on 01 April 1984

Significance of heme oxygenase in prolactin-mediated cell proliferation and angiogenesis in human endothelial cells

scientific article

Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis.

scientific article published on 18 December 2003

Smooth muscle--specific expression of CYP4A1 induces endothelial sprouting in renal arterial microvessels

scientific article published on 11 December 2003

Soluble epoxide hydrolase null mice exhibit female and male differences in regulation of vascular homeostasis

scientific article

Specific inhibition of c-fos proto-oncogene expression by triple-helix-forming oligonucleotides

scientific article

Specificity of heme for hemopoietic recovery from AZT toxicity

scientific article published on 01 January 1992

Successful modulation of type 2 diabetes in db/db mice with intra-bone marrow--bone marrow transplantation plus concurrent thymic transplantation

scientific article published on December 2010

Synergistic effect of heme and IL-1 on hematopoietic stromal regeneration after radiation

scientific article published on 01 November 1993

TNF-alpha-mediated cell death is attenuated by retrovirus delivery of human heme oxygenase-1 gene into human microvessel endothelial cells

article by T Kushida et al published 1 November 2002 in Transplantation Proceedings

Targeting Heme Oxygenase-1 in Cardiovascular and Kidney Disease

scientific article published on 18 June 2019

Targeting endothelial cells with heme oxygenase-1 gene using VE-cadherin promoter attenuates hyperglycemia-mediated cell injury and apoptosis

scientific article

Targeting heme oxygenase: therapeutic implications for diseases of the cardiovascular system

scientific article published on May 2009

Targeting the Heme-Heme Oxygenase System to Prevent Severe Complications Following COVID-19 Infections

scientific article published on 19 June 2020

The Biological Significance and Physiological Role of Heme Oxygenase

scientific article published in 1996

The DDAH/NOS pathway in human prostatic cancer cell lines: Antiangiogenic effect of L-NAME ⬇️

scientific article published on June 30, 2011

The L-4F mimetic peptide prevents insulin resistance through increased levels of HO-1, pAMPK, and pAKT in obese mice

scientific article published on 17 February 2009

The Na/K-ATPase Oxidant Amplification Loop Regulates Aging.

scientific article published on 26 June 2018

The Peroxisome Proliferator-Activated Receptor-Gamma Coactivator-1α-Heme Oxygenase 1 Axis, a Powerful Antioxidative Pathway with Potential to Attenuate Diabetic Cardiomyopathy

scientific article published on 25 March 2020

The Pivotal Role of Adipocyte-Na K peptide in Reversing Systemic Inflammation in Obesity and COVID-19 in the Development of Heart Failure

scientific article published on 14 November 2020

The association of NOV/CCN3 with obstructive sleep apnea (OSA): preliminary evidence of a novel biomarker in OSA.

scientific article published on September 2017

The bone marrow as a metabolic organ

scientific article published on 01 November 1982

The cytochrome P450 metabolic pathway of arachidonic acid in the cornea

scientific article published on January 1, 1991

The emerging role of heme oxygenase and its metabolites in the regulation of cardiovascular function.

scientific article published on 21 October 2012

The hematopoietic stromal microenvironment promotes retrovirus-mediated gene transfer into hematopoietic stem cells

scientific article published in May 1993

The physiological significance of heme oxygenase

scientific article published on January 1988

The pivotal role of heme Oxygenase-1 in reversing the pathophysiology and systemic complications of NAFLD

scientific article published on 26 November 2020

The renal cytochrome P-450 arachidonic acid system

scientific article published on September 1, 1992

The role of NF-kappaB in the angiogenic response of coronary microvessel endothelial cells

scientific article published on April 1996

The toxic effects of heavy metals on rat bone marrow in vitro erythropoiesis: protective role of hemin and zinc

scientific article published on 01 October 1984

Therapeutic approaches to diabetic cardiomyopathy: Targeting the antioxidant pathway

scientific article published on 12 May 2020

Tin-mediated heme oxygenase gene activation and cytochrome P450 arachidonate hydroxylase inhibition in spontaneously hypertensive rats

scientific article published on 01 March 1994

Tissue transglutaminase expression during neural differentiation of human mesenchymal stem cells

scientific article published on 01 January 2015

Transfection and functional expression of CYP4A1 and CYP4A2 using bicistronic vectors in vascular cells and tissues

scientific article

Transfection of the human heme oxygenase gene into rabbit coronary microvessel endothelial cells: protective effect against heme and hemoglobin toxicity

scientific article

Transfer of human adenine deaminase gene into murine hematopoietic stem cells: sequential study of spleen colony-forming units from bone marrow of living mice and the requirement of the microenvironment

scientific article published in January 1996

Translational Significance of Heme Oxygenase in Obesity and Metabolic Syndrome

scientific article

Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance

scientific article

Treatment with tin prevents the development of hypertension in spontaneously hypertensive rats.

scientific article

Up-regulation of heme oxygenase provides vascular protection in an animal model of diabetes through its antioxidant and antiapoptotic effects

scientific article published on 07 September 2006

Up-regulation of heme oxygenase-1 after infarct initiation reduces mortality, infarct size and left ventricular remodeling: experimental evidence and proof of concept

scientific article

Uric Acid-Induced Adipocyte Dysfunction Is Attenuated by HO-1 Upregulation: Potential Role of Antioxidant Therapy to Target Obesity

scientific article

Usefulness of clopidogrel to protect against diabetes-induced vascular damage

scientific article published on April 2010

Zinc porphyrins: potent inhibitors of hematopoieses in animal and human bone marrow

scientific article

pNaKtide Attenuates Steatohepatitis and Atherosclerosis by Blocking Na/K-ATPase/ROS Amplification in C57Bl6 and ApoE Knockout Mice Fed a Western Diet.

scientific article

pNaKtide inhibits Na/K-ATPase reactive oxygen species amplification and attenuates adipogenesis

scientific article

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