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List of works by Bruce N. Ames

'Spontaneous' genetic damage in man: evaluation of interindividual variability, relationship among markers of damage, and influence of nutritional status ⬇️

scientific article published on 01 June 1997

(R)-alpha-lipoic acid protects retinal pigment epithelial cells from oxidative damage

scientific article

(R)-alpha-lipoic acid reverses the age-associated increase in susceptibility of hepatocytes to tert-butylhydroperoxide both in vitro and in vivo

scientific article published on 01 January 2000

29 Detection of oxidative mutagens with a new Salmonella tester strain (TA102)

scientific article published on January 1, 1984

5-Chlorouracil, a marker of DNA damage from hypochlorous acid during inflammation. A gas chromatography-mass spectrometry assay

scientific article

5-Methyltetrahydrofolate inhibits photosensitization reactions and strand breaks in DNA.

scientific article published on 6 March 2007

7-Methylguanine adducts in DNA are normally present at high levels and increase on aging: analysis by HPLC with electrochemical detection

scientific article

8-Hydroxydeoxyguanosine and 8-hydroxyguanine as biomarkers of oxidative DNA damage

scientific article

A Series of Histidineless Mutants of Neurospora Crassa

scientific article published on May 1952

A Simple Method for the Detection of Mutagens in Urine: Studies with the Carcinogen 2-Acetylaminofluorene ⬇️

scientific article published on March 1, 1974

A combination of aspirin and gamma-tocopherol is superior to that of aspirin and alpha-tocopherol in anti-inflammatory action and attenuation of aspirin-induced adverse effects

scientific article

A combined bacterial and liver test system for detection and classification of carcinogens as mutagens ⬇️

scientific article published on September 1, 1974

A method for detecting abasic sites in living cells: age-dependent changes in base excision repair

scientific article

A modified nucleotide in tRNA as a possible regulator of aerobiosis: synthesis of cis-2-methyl-thioribosylzeatin in the tRNA of Salmonella

scientific article published in February 1984

A multicomponent nutrient bar promotes weight loss and improves dyslipidemia and insulin resistance in the overweight/obese: chronic inflammation blunts these improvements

scientific article published on 21 April 2015

A new Salmonella tester strain (TA102) with A X T base pairs at the site of mutation detects oxidative mutagens

scientific article

A new Salmonella tester strain, TA97, for the detection of frameshift mutagens. A run of cytosines as a mutational hot-spot

scientific article published in June 1982

A novel nutritional intervention improves lung function in overweight/obese adolescents with poorly controlled asthma: the Supplemental Nutrition in Asthma Control (SNAC) pilot study

scientific article published on 19 July 2018

A nutrient-dense, high-fiber, fruit-based supplement bar increases HDL cholesterol, particularly large HDL, lowers homocysteine, and raises glutathione in a 2-wk trial.

scientific article

A procedure for rapid extraction and high-pressure liquid chromatographic separation of the nucleotides and other small molecules from bacterial cells

scientific article published in June 1982

A role for supplements in optimizing health: the metabolic tune-up

scientific article published on March 2004

A simple assay for frequency of chromosome breaks and loss (micronuclei) by flow cytometry of human reticulocytes

scientific article published on 15 December 2004

A simple method for detecting environmental carcinogens as mutagens

scientific article published on January 1, 1976

A simpler, more robust method for the analysis of 8-oxoguanine in DNA

scientific article published on 01 August 2000

Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males

scientific article

Acetyl- l -carnitine fed to old rats partially restores mitochondrial function and ambulatory activity ⬇️

scientific article published on August 4, 1998

Acetyl-L-carnitine and alpha-lipoic acid supplementation of aged beagle dogs improves learning in two landmark discrimination tests

scientific article published on 10 July 2007

Acrolein, a toxicant in cigarette smoke, causes oxidative damage and mitochondrial dysfunction in RPE cells: protection by (R)-alpha-lipoic acid

scientific article published on January 2007

Adaptive dysfunction of selenoproteins from the perspective of the triage theory: why modest selenium deficiency may increase risk of diseases of aging ⬇️

scientific article published on March 14, 2011

Adenosine 3':5'-cyclic monophosphate concentration in the bacterial host regulates the viral decision between lysogeny and lysis

scientific article published on September 1971

Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes--reversal with (R)-alpha-lipoic acid supplementation.

scientific article published in September 1998

Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid

scientific article

Alterations in levels of 5'-adenyl dinucleotides following DNA damage in normal human fibroblasts and fibroblasts derived from patients with xeroderma pigmentosum.

scientific article published in June 1988

Alterations of NAD and adenylyl dinucleotide metabolism in Chediak-Higashi syndrome fibroblasts

scientific article

Ames agrees with mom's advice: eat your fruits and vegetables

scientific article published in April 1995

An Adduct between Peroxynitrite and 2‘-Deoxyguanosine: 4,5-Dihydro-5-hydroxy-4-(nitrosooxy)-2‘-deoxyguanosine

An HPLC-EC Assay for 1,N2-Propano Adducts of 2'-Deoxyguanosine with 4-Hydroxynonenal and Other .alpha.,.beta.-Unsaturated Aldehydes

article

An Improved Bacterial Test System for the Detection and Classification of Mutagens and Carcinogens ⬇️

scientific article published on March 1, 1973

An alkyl hydroperoxide reductase from Salmonella typhimurium involved in the defense of DNA against oxidative damage. Purification and properties

scientific article published in January 1989

An alkyl hydroperoxide reductase induced by oxidative stress in Salmonella typhimurium and Escherichia coli: genetic characterization and cloning of ahp

scientific article

An apaH mutation causes AppppA to accumulate and affects motility and catabolite repression in Escherichia coli

scientific article

An assay for uracil in human DNA at baseline: effect of marginal vitamin B6 deficiency

scientific article

An enthusiasm for metabolism

scientific article

An inexpensive luer-fitting chromatographic column ⬇️

scientific article published on 01 April 1967

An overview of evidence for a causal relation between iron deficiency during development and deficits in cognitive or behavioral function

scientific article published on April 2007

An overview of evidence for a causal relationship between dietary availability of choline during development and cognitive function in offspring

scientific article

Analysis of data integrity ⬇️

scientific article published on September 1, 2012

Analysis of plasma tocopherols alpha, gamma, and 5-nitro-gamma in rats with inflammation by HPLC coulometric detection

scientific article published in November 2002

Analysis of uracil in DNA by gas chromatography-mass spectrometry

scientific article

Animal cancer tests and cancer prevention

scientific article published on January 1, 1992

Another Flame Retardant, Tris-(1,3-Dichloro-2-Propyl)-Phosphate, and Its Expected Metabolites Are Mutagens ⬇️

scientific article published on May 19, 1978

Antioxidant activities of bile pigments: biliverdin and bilirubin

scientific article published on 01 January 1990

Antioxidant activity of albumin-bound bilirubin

scientific article

Antioxidant activity of carnosine, homocarnosine, and anserine present in muscle and brain ⬇️

scientific article published on May 1, 1988

Antioxidant activity of diethyldithiocarbamate.

scientific article published in June 1996

Antioxidant defenses and lipid peroxidation in human blood plasma

scientific article

Antioxidant status and indexes of oxidative stress during consecutive days of exercise ⬇️

scientific article published on August 1, 1993

Apoptosis of late-stage erythroblasts in megaloblastic anemia: association with DNA damage and macrocyte production

scientific article published on 01 June 1997

AppppA and related adenylylated nucleotides are synthesized as a consequence of oxidation stress ⬇️

scientific article published on May 1, 1984

AppppA, heat-shock stress, and cell oxidation ⬇️

scientific article published on December 1, 1983

Are vitamin and mineral deficiencies a major cancer risk?

scientific article

Ascorbate is an outstanding antioxidant in human blood plasma

scientific article

Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes.

scientific article published on February 2000

Ascorbate: the most effective antioxidant in human blood plasma

scientific article

Ascorbic acid protects against endogenous oxidative DNA damage in human sperm

scientific article published on December 1991

Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: decline with age.

scientific article published in January 1999

Assay of aldehydes from lipid peroxidation: gas chromatography-mass spectrometry compared to thiobarbituric acid

scientific article published on February 1997

Assay of excised oxidative DNA lesions: isolation of 8-oxoguanine and its nucleoside derivatives from biological fluids with a monoclonal antibody column ⬇️

scientific article published on April 15, 1992

Assay of lipid hydroperoxides using high-performance liquid chromatography with isoluminal chemiluminescence detection

scientific article published on 01 January 1990

Assay of malondialdehyde and other alkanals in biological fluids by gas chromatography-mass spectrometry.

scientific article published in January 1999

Assay of malondialdehyde in biological fluids by gas chromatography-mass spectrometry.

scientific article

Assays for 8-hydroxy-2′-deoxyguanosine: A biomarker of in vivo oxidative DNA damage ⬇️

scientific article published on January 1, 1991

Assays of oxidative DNA damage biomarkers 8-oxo-2'-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection

scientific article published in January 1994

Association of chromosome damage detected as micronuclei with hematological diseases and micronutrient status ⬇️

scientific article published on January 1, 2011

Background levels of DNA damage in the population

scientific article published on 01 January 1986

Bilirubin is an antioxidant of possible physiological importance

scientific article

Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning?

scientific article published on March 2005

Biomarkers of oxidative stress study III. Effects of the nonsteroidal anti-inflammatory agents indomethacin and meclofenamic acid on measurements of oxidative products of lipids in CCl4 poisoning.

scientific article

Biosynthesis of pseudouridine in transfer ribonucleic acid.

scientific article

Biotin deficiency inhibits heme synthesis and impairs mitochondria in human lung fibroblasts

scientific article published on 01 January 2007

Both iron deficiency and daily iron supplements increase lipid peroxidation in rats

scientific article published on March 2000

COORDINATE REPRESSION OF THE SYNTHESIS OF FOUR HISTIDINE BIOSYNTHETIC ENZYMES BY HISTIDINE.

scientific article published in October 1959

Cancer prevention and diet: help from single nucleotide polymorphisms

scientific article

Cancer prevention, rodent high-dose cancer tests, and risk assessment

scientific article published on 01 October 1996

Carcinogenesis debate.

scientific article

Carcinogens and anti-carcinogens

scientific article published on 01 January 1982

Carcinogens and anticarcinogens

scientific article

Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection

scientific article

Carcinogens are mutagens: their detection and classification

scientific article published on December 1973

Carcinogens as Frameshift Mutagens: Metabolites and Derivatives of 2-Acetylaminofluorene and Other Aromatic Amine Carcinogens ⬇️

scientific article published on November 1, 1972

Charles S. Mott prize. The detection of environmental mutagens and potential carcinogens ⬇️

scientific article published on May 15, 1984

Chemical carcinogenesis: too many rodent carcinogens

scientific article

Children absorb tris-BP flame retardant from sleepwear: urine contains the mutagenic metabolite, 2,3-dibromopropanol

scientific article published on September 15, 1978

Chromosomal alterations affecting the regulation of histidine biosynthetic enzymes in Salmonella

scientific article published in July 1963

Chronic ethanol perturbs testicular folate metabolism and dietary folate deficiency reduces sex hormone levels in the Yucatan micropig

scientific article

Chronically and acutely exercised rats: biomarkers of oxidative stress and endogenous antioxidants

scientific article published on July 2000

Chronological supplement to the Carcinogenic Potency Database: standardized results of animal bioassays published through December 1982.

scientific article

Classification of aminotransferase (C gene) mutants in the histidine operon

scientific article published in November 1966

Classifying mutagens as to their specificity in causing the six possible transitions and transversions: a simple analysis using the Salmonella mutagenicity assay

scientific article published in January 1986

Clinical assay of four thiol amino acid redox couples by LC-MS/MS: utility in thalassemia

scientific article

Comparison of the effects of L-carnitine and acetyl-L-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats

scientific article

Compatibility of organic solvents with the Salmonella/microsome test

scientific article published in April 1981

Complete analysis of cellular nucleotides by two-dimensional thin layer chromatography ⬇️

scientific article published on August 25, 1982

Complete analysis of tRNA-modified nucleosides by high-performance liquid chromatography: The 29 modified nucleosides of Salmonella typhimurium and Escherichia coli tRNA ⬇️

scientific article published on February 15, 1983

Compounds Which Serve as the Sole Source of Carbon or Nitrogen for Salmonella typhimurium LT-2 ⬇️

scientific article

Concentration of mutagens from urine by absorption with the nonpolar resin XAD-2: cigarette smokers have mutagenic urine ⬇️

scientific article published on August 1, 1977

Cyclic 3', 5'-adenosine monophosphate phosphodiesterase mutants of Salmonella typhimurium ⬇️

scientific article published on June 1, 1975

Cytogenetic damage induced by folate deficiency in mice is enhanced by caffeine

scientific article

DNA damage from micronutrient deficiencies is likely to be a major cause of cancer

scientific article

DNA damage in folate deficiency

scientific article published on September 1995

DNA lesions, inducible DNA repair, and cell division: three key factors in mutagenesis and carcinogenesis

scientific article

DNA oxidation matters: The HPLC–electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine ⬇️

scientific article published on January 6, 1998

DOES THE OXIDATIVE STRESS AND CEREBRAL ATHEROSCLEROSIS INITIATE BRAIN HYPOPERFUSION AND THE DEVELOPMENT OF ALZHEIMER DISEASE?

Daily supplementation with iron increases lipid peroxidation in young women with low iron stores.

scientific article

Daniel e. Koshland, jr., new editor of science

scientific article

Decreases in tissue levels of ubiquinol-9 and -10, ascorbate and alpha-tocopherol following spinal cord impact trauma in rats

scientific article published on 01 January 1990

Delaying Aging with Mitochondrial Micronutrients and Antioxidants

scientific article published on 24 September 2001

Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites

scientific article

Delaying the mitochondrial decay of aging

scientific article published in June 2004

Delaying the mitochondrial decay of aging with acetylcarnitine

scientific article

Delaying the mitochondrial decay of aging-a metabolic tune-up.

scientific article

Design and Synthesis of Novel Non-nucleoside Anti-HCMV Agents

scientific article published in 2008

Detection and characterization of lipid hydroperoxides at picomole levels by high-performance liquid chromatography

scientific article published on 01 January 1987

Detection and classification of mutagens: a set of base-specific Salmonella tester strains

scientific article published in November 1994

Detection and quantification of oxidative adducts of mitochondrial DNA.

scientific article published in January 1996

Detection of DNA adducts by high-performance liquid chromatography with electrochemical detection

scientific article

Detection of DNA base damage by 32P-postlabelling: TLC separation of 5'-deoxynucleoside monophosphates

scientific article published on 01 January 1986

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals ⬇️

scientific article published on December 1, 1975

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion ⬇️

scientific article published on March 1, 1976

Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids ⬇️

scientific article published on March 1, 1975

Detection of lipid hydroperoxides and hydrogen peroxide at picomole levels by an HPLC and isoluminol chemiluminescence assay

scientific article published on January 1987

Detection of mutagenic activity in cigarette smoke condensates

scientific article

Detection of mutagenic impurities in carcinogens and noncarcinogens by high-pressure liquid chromatography and the Salmonella/microsome test ⬇️

scientific article published on February 1, 1978

Detection of phosphate esters on chromatograms: an improved reagent

scientific article published on 01 October 1981

Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay

scientific article published on 01 October 1983

Detection of picomole levels of lipid hydroperoxides using a dichlorofluorescein fluorescent assay

scientific article published on 01 January 1984

Determination of 8-hydroxydeoxyguanosine in human urine: a possible assay for in vivo oxidative DNA damage

scientific article published on 01 January 1988

Development of a sensitive assay for detection of uracil in DNA.

scientific article published in January 1993

Diadenosine 5',5"'-P1,P4-tetraphosphate and related adenylylated nucleotides in Salmonella typhimurium ⬇️

scientific article published on June 10, 1983

Dietary carcinogens and anti-carcinogens

scientific article published on 01 January 1984

Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases

scientific article

Dietary carcinogens, environmental pollution, and cancer: some misconceptions

scientific article published on January 1990

Dietary pesticides (99.99% all natural)

scientific article

Discussion paper: the detection of mutagenic metabolites of carcinogens in urine with the Salmonella/microsome test

scientific article published on December 31, 1975

Effect of ebselen on Ca2+ transport in mitochondria

scientific article

Effect of the α-Hydrazino Analogue of Histidine on Histidine Transport and Arginine Biosynthesis ⬇️

scientific article published in July 1966

Effects of a peroxisomal proliferator (PP) on plasma and tissue levels of coenzyme Q9 (CoQ), other antioxidants, and oxidative damage to DNA (oxo8dG): evidence that PPs deplete antioxidants and increase oxidative damage to DNA

scientific article published on 01 January 1994

Endogenous DNA damage as related to cancer and aging

scientific article published on September 1989

Endogenous mutagens and the causes of aging and cancer

scientific article

Endogenous oxidative DNA damage, aging, and cancer

scientific article published on January 1989

Endogenous oxidative damage of deoxycytidine in DNA.

scientific article published on April 1992

Endogenous oxidative damage of mtDNA.

scientific article

Energy charge and protein synthesis. Control of aminoacyl transfer ribonucleic acid synthetases

scientific article published in January 1970

Enough is enough

scientific article published on 01 June 2014

Enriched selection of dominant mutations: histidine operator mutations

scientific article published on August 1971

Environmental Pollution, Pesticides, and the Prevention of Cancer: Misconceptions 1 ⬇️

scientific article published on November 1, 1997

Epoxides of Carcinogenic Polycyclic Hydrocarbons Are Frameshift Mutagens ⬇️

scientific article published on April 7, 1972

Erythrocyte glutamine depletion, altered redox environment, and pulmonary hypertension in sickle cell disease

scientific article

Evaluation of an isoluminol chemiluminescence assay for the detection of hydroperoxides in human blood plasma.

scientific article published in November 1988

Evidence-based decision making on micronutrients and chronic disease: long-term randomized controlled trials are not enough

scientific article published on 01 August 2007

Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma

scientific article

Extrapolation of carcinogenicity between species: qualitative and quantitative factors

scientific article published on December 1, 1992

Falsche Annahmen über die Zusammenhänge zwischen der Umweltverschmutzung und der Entstehung von Krebs

article

Fe(2+) induces a transient Ca(2+) release from rat liver mitochondria

scientific article published in February 2002

Fecalase: a model for activation of dietary glycosides to mutagens by intestinal flora

scientific article

Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress

scientific article

Flame-retardant additives as possible cancer hazards

scientific article published on January 7, 1977

Fluorescence detection of 8-oxoguanine in nuclear and mitochondrial DNA of cultured cells using a recombinant Fab and confocal scanning laser microscopy.

scientific article

Folate deficiency and ionizing radiation cause DNA breaks in primary human lymphocytes: a comparison

scientific article published on 3 November 2003

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage

scientific article

Folate deficiency inhibits the proliferation of primary human CD8+ T lymphocytes in vitro

scientific article

Food constituents as a source of mutagens, carcinogens, and anticarcinogens

scientific article published on January 1986

Frameshift mutagenesis in Salmonella

scientific article published in January 1966

Gamma-tocopherol attenuates ozone-induced exacerbation of allergic rhinosinusitis in rats

scientific article published on 23 April 2009

Gamma-tocopherol induces apoptosis in androgen-responsive LNCaP prostate cancer cells via caspase-dependent and independent mechanisms

scientific article

Gamma-tocopherol prevents airway eosinophilia and mucous cell hyperplasia in experimentally induced allergic rhinitis and asthma

scientific article published on 26 October 2007

Gamma-tocopherol supplementation inhibits protein nitration and ascorbate oxidation in rats with inflammation

scientific article published on December 2002

Gas phase oxidants of cigarette smoke induce lipid peroxidation and changes in lipoprotein properties in human blood plasma. Protective effects of ascorbic acid ⬇️

scientific article published on July 1, 1991

Guanosine 5'-diphosphate 3'-diphosphate (ppGpp): positive effector for histidine operon transcription and general signal for amino-acid deficiency ⬇️

scientific article published on November 1, 1975

Hair dyes are mutagenic: identification of a variety of mutagenic ingredients ⬇️

scientific article published on June 1, 1975

Heme deficiency may be a factor in the mitochondrial and neuronal decay of aging

scientific article

Heme deficiency selectively interrupts assembly of mitochondrial complex IV in human fibroblasts: revelance to aging

scientific article published on 11 October 2001

Heterocyclic amines formed by cooking food: comparison of bioassay results with other chemicals in the Carcinogenic Potency Database

scientific article published on August 1994

High-dose vitamin therapy stimulates variant enzymes with decreased coenzyme binding affinity (increased K(m)): relevance to genetic disease and polymorphisms

scientific article (publication date: April 2002)

Histidine regulation in Salmonella typhimurium. 8. Mutations of the hisT gene

scientific article published on October 1971

Histidine regulation in Salmonella typhimurium. IX. Histidine transfer ribonucleic acid of the regulatory mutants

scientific article published in February 1972

Histidine regulation in Salmonella typhimurium. VII. Purification and general properties of the histidyl transfer ribonucleic acid synthetase

scientific article

Histidine regulation in Salmonella typhimurium. X. Kinetic studies of mutant histidyl transfer ribonucleic acid synthetases.

scientific article published in April 1972

Histidine regulation in Salmonella typhimurium. XI. The percentage of transfer RNA His charged in vivo and its relation to the repression of the histidine operon

scientific article published in April 1972

Histidine regulation in Salmonella typhimurium. XVI. A sensitive radiochemical assay for histidinol dehydrogenase

scientific article published in January 1975

Histidine regulation in salmonella typhimurium. XIV. Interaction of the histidyl transfer ribonucleic acid synthetase with histidine transfer ribonucleic acid

scientific article published in July 1972

Histidine regulatory mutants in Salmonella typhimurium 3. A class of regulatory mutants deficient in tRNA for histidine

scientific article published in December 1966

Histidine regulatory mutants in Salmonella typhimurium II. Histidine regulatory mutants having altered histidyl-tRNA synthetase

scientific article published in December 1966

Histidine regulatory mutants in Salmonella typhimurium. IV. A positive selection for polar histidine-requiring mutants from histidine operator constitutive mutants

scientific article published in November 1967

Histidyl-transfer ribonucleic acid synthetase mutants requiring a high internal pool of histidine for growth

scientific article published on July 1973

Hydrogen peroxide-inducible proteins in Salmonella typhimurium overlap with heat shock and other stress proteins

scientific article

Hydroxymethyluracil DNA glycosylase in mammalian cells

scientific article

INTERMEDIATES IN THE EARLY STEPS OF HISTIDINE BIOSYNTHESIS

scientific article published in June 1964

Identification and molecular analysis of oxyR-regulated promoters important for the bacterial adaptation to oxidative stress

scientific article published in December 1989

Identifying Environmental Chemicals Causing Mutations and Cancer ⬇️

scientific article published on May 11, 1979

Illicit Transport: The Oligopeptide Permease ⬇️

scientific article published on February 1, 1973

Immobilization stress causes oxidative damage to lipid, protein, and DNA in the brain of rats

scientific article

Immunoaffinity isolation of urinary 8-hydroxy-2'-deoxyguanosine and 8-hydroxyguanine and quantitation of 8-hydroxy-2'-deoxyguanosine in DNA by polyclonal antibodies

scientific article published in May 1991

Immunochemical identification of a tRNA-independent cytokinin-like compound in Salmonella typhimurium

scientific article published in March 1989

Immunocompetence and oxidant defense during ascorbate depletion of healthy men.

scientific article published in December 1991

Immunodetection of 3-nitrotyrosine in the liver of zymosan-treated rats with a new monoclonal antibody: comparison to analysis by HPLC.

scientific article published in December 2001

In reply: cancer and diet

scientific article published on 01 May 1984

In reply: carcinogenic risk estimation.

scientific article

In reply: carcinogens and human health: part 1

scientific article published on 01 December 1990

In vivo oxidative DNA damage: measurement of 8-hydroxy-2'-deoxyguanosine in DNA and urine by high-performance liquid chromatography with electrochemical detection

scientific article published on 01 January 1990

Increased leucocyte apoptosis in transfused β‐thalassaemia patients ⬇️

scientific article published on December 6, 2012

Increasing longevity by tuning up metabolism. To maximize human health and lifespan, scientists must abandon outdated models of micronutrients

scientific article

Induction of cytochrome P4501A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin or indolo(3,2-b)carbazole is associated with oxidative DNA damage

scientific article

Inflammation and NO(X)-induced nitration: assay for 3-nitrotyrosine by HPLC with electrochemical detection

scientific article

Inhibition of simian virus 40 DNA replication in vitro by poly(ADP-ribosyl)ated diadenosine tetraphosphate

scientific article

International Commission for Protection Against Environmental Mutagens and Carcinogens. ICPEMC Publication No. 12. Inhibitors of mutagenesis and their relevance to carcinogenesis. Report by ICPEMC Expert Group on Antimutagens and Desmutagens

scientific article

Intestinal cell proliferation is influenced by intakes of protein and energy, aflatoxin, and whole-body radiation

scientific article published in January 1994

Iron Accumulation During Cellular Senescence in Human FibroblastsIn Vitro ⬇️

scientific article published on October 1, 2003

Iron Transport in Salmonella typhimurium: Mutants Blocked in the Biosynthesis of Enterobactin ⬇️

scientific article published on November 1, 1970

Iron Uptake in Salmonella typhimurium : Utilization of Exogenous Siderochromes as Iron Carriers ⬇️

scientific article published on September 1, 1972

Iron accumulation during cellular senescence

scientific article published in June 2004

Iron deficiency and iron excess damage mitochondria and mitochondrial DNA in rats.

scientific article

Is docosahexaenoic acid, an n-3 long-chain polyunsaturated fatty acid, required for development of normal brain function? An overview of evidence from cognitive and behavioral tests in humans and animals

scientific article

Is oxidative stress an initiator of mitochondrial failure and vascular hypoperfusion during aging and Alzheimer disease? Present and future

Is there convincing biological or behavioral evidence linking vitamin D deficiency to brain dysfunction?

scientific article published on 04 December 2007

Isolation and characterization of a selenium metabolism mutant of Salmonella typhimurium

scientific article

Leukemia in twins: antenatal and postnatal factors

scientific article published on 01 January 1976

Lipoic acid and acetyl-carnitine reverse iron-induced oxidative stress in human fibroblasts

scientific article published on January 2008

Localized mutagenesis of any specific small region of the bacterial chromosome

scientific article published on December 1971

Low intracellular zinc induces oxidative DNA damage, disrupts p53, NFkappa B, and AP1 DNA binding, and affects DNA repair in a rat glioma cell line

scientific article

Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage

scholarly article

Low seminal plasma folate concentrations are associated with low sperm density and count in male smokers and nonsmokers

scientific article

Magnesium deficiency accelerates cellular senescence in cultured human fibroblasts

scholarly article

Maternal dietary zinc influences DNA strand break and 8-hydroxy-2'-deoxyguanosine levels in infant rhesus monkey liver

scientific article published in September 1993

Measurement of antioxidants in human blood plasma

scientific article published in January 1994

Measuring chromosome breaks in patients with thalassemia

scientific article published in January 2005

Measuring oxidative damage in humans: relation to cancer and ageing.

scientific article

Mechanisms of mutagenicity and toxicity of sodium selenite (Na2SeO3) in Salmonella typhimurium

scientific article

Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid

scientific article

Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test

scientific article published on December 1, 1975

Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways

scientific article

Methylenetetrahydrofolate reductase C677T polymorphism does not alter folic acid deficiency-induced uracil incorporation into primary human lymphocyte DNA in vitro

scientific article published in July 2001

Micronutrient deficiencies. A major cause of DNA damage

scientific article

Micronutrients prevent cancer and delay aging

scientific article

Mineral and vitamin deficiencies can accelerate the mitochondrial decay of aging

scientific article

Mitochondrial aging: open questions.

scientific article published in November 1998

Mitochondrial decay in aging ⬇️

scientific article published on May 24, 1995

Mitochondrial decay in aging. Reversal through supplementation of acetyl-L-carnitine and N-tert-butyl-alpha-phenyl-nitrone

scientific article

Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase

scientific article

Mitochondrial decay in the brains of old rats: ameliorating effect of alpha-lipoic acid and acetyl-L-carnitine

scientific article published on 10 October 2008

Mitochondrial decay, a major cause of aging, can be delayed.

scientific article published in April 2004

Mitogenesis, mutagenesis, and animal cancer tests

scientific article published on January 1991

Mode of action of the herbicide, 3-amino-1,2,4-triazole(amitrole): inhibition of an enzyme of histidine biosynthesis

scientific article

Moderate antioxidant supplementation has no effect on biomarkers of oxidant damage in healthy men with low fruit and vegetable intakes.

scientific article

Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication ⬇️

scientific article published on May 15, 1998

Multidegenerate DNA recognition by the OxyR transcriptional regulator ⬇️

scientific article published on January 25, 1992

Mutagenesis and carcinogenesis: endogenous and exogenous factors

scientific article published on January 1989

Mutagenicity of cancer chemotherapeutic agents in the Salmonella/microsome test ⬇️

scientific article published on July 1, 1977

Mutagenicity of chloroacetaldehyde, a possible metabolic product of 1,2-dichloroethane (ethylene dichloride), chloroethanol (ethylene chlorohydrin), vinyl chloride, and cyclophosphamide ⬇️

scientific article published on August 1, 1975

Mutagenicity of nitric oxide in base pair-specific Salmonella tester strains: TA7000 series

scientific article published on January 1996

Mutagenicity of quinones: pathways of metabolic activation and detoxification

scientific article

Mutagens and carcinogens

scientific article published on 01 October 1976

Mutagens, carcinogens, and anti-carcinogens.

scientific article published in January 1982

Mutant tRNAHis Ineffective in Repression and Lacking Two Pseudouridine Modifications ⬇️

scientific article published on July 19, 1972

N-t-butyl hydroxylamine, a hydrolysis product of alpha-phenyl-N-t-butyl nitrone, is more potent in delaying senescence in human lung fibroblasts

scientific article published on March 2000

N-tert-butyl hydroxylamine, a mitochondrial antioxidant, protects human retinal pigment epithelial cells from iron overload: relevance to macular degeneration.

scientific article published on 26 July 2007

N2-methyl-8-oxoguanine: a tRNA urinary metabolite--role of xanthine oxidase

scientific article published in January 1996

Natural carcinogens and dioxin

scientific article published on May 1991

Natural chemicals, synthetic chemicals, risk assessment, and cancer

scientific article published on 01 January 1990

Naturally occurring carbonyl compounds are mutagens in Salmonella tester strain TA104.

scientific article published in January 1985

Nature's chemicals and synthetic chemicals: comparative toxicology

scientific article

Nature's pesticides

scientific article published on 01 January 1992

Near-UV stress in Salmonella typhimurium: 4-thiouridine in tRNA, ppGpp, and ApppGpp as components of an adaptive response

scientific article

Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats

scientific article published on 28 March 2008

Normal oxidative damage to mitochondrial and nuclear DNA is extensive ⬇️

scientific article published on September 1, 1988

N‐ t ‐Butyl hydroxylamine is an antioxidant that reverses age‐related changes in mitochondria in vivo and in vitro ⬇️

scientific article published on October 1, 2001

Optimal micronutrients delay mitochondrial decay and age-associated diseases

scientific article published on 24 April 2010

Oxidants and mitogenesis as causes of mutation and cancer: the influence of diet.

scientific article published on January 1993

Oxidants are a major contributor to aging

scientific article published on November 21, 1992

Oxidants, antioxidants, and the degenerative diseases of aging

scientific article

Oxidative DNA damage and senescence of human diploid fibroblast cells.

scientific article

Oxidative DNA damage as related to cancer and aging.

scientific article

Oxidative Decay of DNA ⬇️

scientific article published on August 8, 1997

Oxidative damage and mitochondrial decay in aging

scientific article

Oxidative damage increases with age in a canine model of human brain aging

scientific article

Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine

scientific article

Oxidative damage to DNA: relation to species metabolic rate and life span

scientific article

Oxidative damage to plasma constituents by ozone

scientific article published on 01 February 1992

Oxidative mechanisms of toxicity of low-intensity near-UV light in Salmonella typhimurium

scientific article

Oxidative stress and abnormal cholesterol metabolism in patients with adult respiratory distress syndrome.

scientific article published in April 1990

Oxidative susceptibility of low density lipoprotein subfractions is related to their ubiquinol-10 and alpha-tocopherol content

scientific article published on February 1994

OxyR, a positive regulator of hydrogen peroxide-inducible genes in Escherichia coli and Salmonella typhimurium, is homologous to a family of bacterial regulatory proteins

scientific article

Oxygen radicals and 8-hydroxyguanine in DNA

scientific article published on December 1, 1991

Oxygen radicals and human disease

scientific article published on October 1987

Ozone enhancement of lower airway allergic inflammation is prevented by gamma-tocopherol

scientific article published on 20 July 2007

PHOSPHORIBOSYLADENOSINE MONOPHOSPHATE, AN INTERMEDIATE IN HISTIDINE BIOSYNTHESIS

scientific article (publication date: July 1965)

Paracelsus to parascience: the environmental cancer distraction

scientific article

Part 2-Unusual clustering of coefficients of variation in published articles from a medical biochemistry department in India

scientific article published in March 2009

Pesticide residues in food: investigation of disparities in cancer risk estimates ⬇️

scientific article published on August 19, 1997

Pesticides, risk, and applesauce

scientific article published on 01 May 1989

Pleiotropy of hisT mutants blocked in pseudouridine synthesis in tRNA: leucine and isoleucine-valine operons

scientific article published on May 1974

Positive control of a regulon for defenses against oxidative stress and some heat-shock proteins in Salmonella typhimurium

scientific article published on July 1985

Positive selection for loss of tetracycline resistance.

scientific article

Positive selection of mutants with deletions of the gal-chl region of the Salmonella chromosome as a screening procedure for mutagens that cause deletions ⬇️

scientific article published on January 1, 1975

Possible Obstetric Factors Effecting Leukemia in Twins ⬇️

scientific article published on 01 October 1975

Potential role of conjugated bilirubin and copper in the metabolism of lipid peroxides in bile

scientific article

Pre-treatment with R-lipoic acid alleviates the effects of GSH depletion in PC12 cells: implications for Parkinson's disease therapy

scientific article published in October 2002

Presence of polyamines in certain bacterial viruses

scientific article published on 01 April 1958

Preventative effect of mitochondrial antioxidants in apoe deficiency mouse model of brain hypoperfusion

Prevention of Mutation, Cancer, and Other Age‐Associated Diseases by Optimizing Micronutrient Intake ⬇️

scientific article published on September 22, 2010

Procedure for Identifying Nonsense Mutations ⬇️

scientific article

Proceedings: carcinogens are mutagens: a simple test system

scientific article published on November 1, 1975

Prolonging healthy aging: Longevity vitamins and proteins

article published in the Proceedings of the National Academy of Sciences of the United States of America

Properties of two phosphatases and a cyclic phosphodiesterase of Salmonella typhimurium ⬇️

scientific article published on April 1, 1977

Protein oxidation associated with aging is reduced by dietary restriction of protein or calories

scientific article published on October 1992

Pseudouridylation of tRNAs and its role in regulation in Salmonella typhimurium ⬇️

scientific article published on June 25, 1979

Quantitation of age-related mitochondrial DNA deletions in rat tissues shows that their pattern of accumulation differs from that of humans ⬇️

scientific article published on March 16, 1998

Randomized nutrient bar supplementation improves exercise-associated changes in plasma metabolome in adolescents and adult family members at cardiometabolic risk

scientific article published on 20 October 2020

Ranking possible carcinogenic hazards

scientific article

Re: E. Farber, Cell proliferation as a major risk factor for cancer: a concept of doubtful validity. Cancer Res., 55: 3759-3762, 1995

Reducing mitochondrial decay with mitochondrial nutrients to delay and treat cognitive dysfunction, Alzheimer's disease, and Parkinson's disease

scientific article

Regulation of nonspecific acid phosphatase in Salmonella: phoN and phoP genes ⬇️

scientific article published on April 1, 1979

Regulation of two phosphatases and a cyclic phosphodiesterase of Salmonella typhimurium ⬇️

scientific article published on April 1, 1977

Resolution and purification of three periplasmic phosphatases of Salmonella typhimurium ⬇️

scientific article published on April 1, 1977

Response

scientific article published on 01 February 1991

Response

article published in 1991

Response: paleolithic diet, evolution, and carcinogens

scientific article published on 01 December 1987

Revised methods for the Salmonella mutagenicity test ⬇️

scientific article published on May 1, 1983

Rodent carcinogens: setting priorities

scientific article published on October 9, 1992

Salmonella typhimurium mutants with alternate requirements for vitamin B 6 or isoleucine

scientific article published on October 1971

Screening for mutagenic activity of some molluscicides ⬇️

scientific article published on January 1, 1975

Second chronological supplement to the Carcinogenic Potency Database: standardized results of animal bioassays published through December 1984 and by the National Toxicology Program through May 1986.

scientific article

Selective precipitation orthophosphate from mixtures containing labile phosphorylated metabolites

scientific article published in May 1982

Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.

scientific article

Sensitive fluorographic detection of 3H and 14C on chromatograms using methyl anthranilate as a scintillant

scientific article published on 01 June 1983

Sequence specificity of tRNA-modifying enzymes. An analysis of 258 tRNA sequences

scientific article published in November 1983

Six common errors relating to environmental pollution

scientific article published in December 1987

Sixth plot of the carcinogenic potency database: results of animal bioassays published in the General Literature 1989 to 1990 and by the National Toxicology Program 1990 to 1993.

scientific article

Smoking and low antioxidant levels increase oxidative damage to sperm DNA.

scientific article

Some tautologous aspects of the comparison of carcinogenic potency in rats and mice

scientific article published on 01 February 1985

Spontaneous and mutagen-induced deletions: mechanistic studies in Salmonella tester strain TA102

scientific article

Spontaneous mutagenesis and oxidative damage to DNA in Salmonella typhimurium

scientific article

Sunlight Ultraviolet and Bacterial DNA Base Ratios ⬇️

scientific article published on November 20, 1970

Supplementation of postmenopausal women with fish oil rich in eicosapentaenoic acid and docosahexaenoic acid is not associated with greater in vivo lipid peroxidation compared with oils rich in oleate and linoleate as assessed by plasma malondialdeh

scientific article published on 01 September 2000

Supplements and tuning up metabolism

scientific article published on 01 November 2004

THE EFFECT OF POLYAMINES AND OF POLY U SIZE ON PHENYLALANINE INCORPORATION.

scientific article

Target sequences for mutagenesis in Salmonella histidine-requiring mutants.

scientific article

The Carcinogenic Potency Database: analyses of 4000 chronic animal cancer experiments published in the general literature and by the U.S. National Cancer Institute/National Toxicology Program

scientific article

The Detection of Chemical Mutagens with Enteric Bacteria

scholarly article published 1971

The Free Radical Theory of Aging Matures ⬇️

scientific article (publication date: April 1998)

The Metabolic Tune-Up: Metabolic Harmony and Disease Prevention ⬇️

scientific article published on May 1, 2003

The OxyR regulon

scientific article published on October 1990

The Role of Polyamines in the Neutralization of Bacteriophage Deoxyribonucleic Acid

scientific article published on 06 January 2021

The TD50: a proposed general convention for the numerical description of the carcinogenic potency of chemicals in chronic-exposure animal experiments

scientific article published in December 1984

The biosynthesis of histidine: imidazoleacetol phosphate transaminase

scientific article published in May 1956

The biosynthesis of histidine; D-erythro-imidazoleglycerol phosphate dehydrase

scientific article (publication date: September 1957)

The biosynthesis of histidine; L-histidinol phosphate phosphatase

scientific article (publication date: June 1957)

The biosynthesis of histidine; imidazoleglycerol phosphate, imidazoleacetol phosphate, and histidinol phosphate ⬇️

scientific article published on 01 February 1955

The case for strategic international alliances to harness nutritional genomics for public and personal health

scientific article published in November 2005

The causes and prevention of cancer

scientific article

The causes and prevention of cancer: gaining perspective ⬇️

scientific article published on June 1, 1997

The causes and prevention of cancer: the role of environment

scientific article published on January 1, 1998

The effect of acetyl-L-carnitine and R-alpha-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimer's disease

scientific article published on April 2009

The effect of folic acid deficiency and MTHFR C677T polymorphism on chromosome damage in human lymphocytes in vitro.

scientific article

The fifth plot of the Carcinogenic Potency Database: results of animal bioassays published in the general literature through 1988 and by the National Toxicology Program through 1989.

scientific article

The genetic control of the enzymes of histidine biosynthesis in Salmonella typhimurium

scientific article published in April 1960

The importance of ranking possible carcinogenic hazards using HERP.

scientific article published on December 1990

The leader mRNA of the histidine attenuator region resembles tRNAHis: possible general regulatory implications ⬇️

scientific article published on September 1, 1983

The operon concept in bacteria and in higher organisms

scientific article published on 01 November 1967

The oxidation of blood plasma and low density lipoprotein components by chemically generated singlet oxygen.

scientific article published in September 1993

The prevention of cancer

scientific article published on 01 May 1998

The primary pathogenetic role of vascular contains vasoactive substances, hypoperfusion, mitochondria failure and oxidative stress in aging and Alzheimer disease

The role of Fe2+-induced lipid peroxidation in the initiation of the mitochondrial permeability transition.

scientific article

The role of heme and iron-sulfur clusters in mitochondrial biogenesis, maintenance, and decay with age.

scientific article

Thiol/redox metabolomic profiling implicates GSH dysregulation in early experimental graft versus host disease (GVHD).

scientific article

Third chronological supplement to the carcinogenic potency database: standardized results of animal bioassays published through December 1986 and by the National Toxicology Program through June 1987.

scientific article

Thymine glycol and thymidine glycol in human and rat urine: a possible assay for oxidative DNA damage

scientific article

Time to talk SENS: critiquing the immutability of human aging.

scientific article

Too many rodent carcinogens: mitogenesis increases mutagenesis

scientific article

Toxaphene, a Complex Mixture of Polychloroterpenes and a Major Insecticide, Is Mutagenic ⬇️

scientific article published on August 10, 1979

Toxic hydroperoxides in intravenous lipid emulsions used in preterm infants.

scientific article published in January 1993

Toxicity and carcinogenic potency.

scientific article

Transfer RNA and the control of the histidine operon

scientific article published in January 1966

Transport of antibiotics and metabolite analogs by systems under cyclic AMP control: positive selection of Salmonella typhimurium cya and crp mutants ⬇️

scientific article published on January 1, 1978

Ubiquinol-10 is an effective lipid-soluble antioxidant at physiological concentrations

scientific article

Understanding the causes of aging and cancer

scientific article published on September 1, 1995

Unusual clustering of coefficients of variation in published articles from a medical biochemistry department in India

scientific article published on 21 October 2008

Uracil in DNA, determined by an improved assay, is increased when deoxynucleosides are added to folate-deficient cultured human lymphocytes

scientific article

Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis

scientific article

Urinary 8-hydroxy-2'-deoxyguanosine as a biological marker of in vivo oxidative DNA damage

scientific journal article

Use of intravenous lipids in neonates

scientific article published on 01 May 1995

Validation of the Salmonella test: a reply to Rinkus and Legator.

scientific article published in October 1981

Vitamin D and the omega-3 fatty acids control serotonin synthesis and action, part 2: relevance for ADHD, bipolar disorder, schizophrenia, and impulsive behavior

scientific article

Vitamin D hormone regulates serotonin synthesis. Part 1: relevance for autism

scientific article

Vitamin E forms inhibit IL-13/STAT6-induced eotaxin-3 secretion by up-regulation of PAR4, an endogenous inhibitor of atypical PKC in human lung epithelial cells ⬇️

scientific article published on July 20, 2011

Vitamin K, an example of triage theory: is micronutrient inadequacy linked to diseases of aging?

scientific article published on 19 August 2009

What are the major carcinogens in the etiology of human cancer? Environmental pollution, natural carcinogens, and the causes of human cancer: six errors

scientific article published in January 1989

What do Animal Cancer Tests Tell us About Human Cancer Risk?: Overview of Analyses of the Carcinogenic Potency Database ⬇️

scientific article published on May 1, 1998

ZTP (5-amino 4-imidazole carboxamide riboside 5′-triphosphate): A proposed alarmone for 10-formyl-tetrahydrofolate deficiency ⬇️

scientific article published on July 1, 1982

Zinc deficiency induces oxidative DNA damage and increases p53 expression in human lung fibroblasts

scientific article published in August 2003

[8] Singlet oxygen DNA damage: Chromatographic and mass spectrometric analysis of damage products

scientific article published in 1994

cis 2-Methylthio-ribosylzeatin (ms2io6A) is present in the transfer RNA of Salmonella typhimurium, but not Escherichia coli.

scientific article published on September 1982

gamma-Tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis

scholarly article

gamma-tocopherol and its major metabolite, in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells

scientific article

gamma-tocopherol traps mutagenic electrophiles such as NO(X) and complements alpha-tocopherol: physiological implications

scientific article

gamma-tocopherol, the major form of vitamin E in the US diet, deserves more attention

scientific article

γ‐Tocopherol, but not α‐tocopherol, decreases proinflammatory eicosanoids and inflammation damage in rats ⬇️

scientific article published on May 1, 2003

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