Search filters

List of works by William P. Tansey

6-Azauracil Sensitivity Assay for Yeast ⬇️

scientific article published on 01 December 2006

A common functional consequence of tumor-derived mutations within c-MYC.

scientific article

A conserved element in Myc that negatively regulates its proapoptotic activity

scientific article

A nonconserved surface of the TFIIB zinc ribbon domain plays a direct role in RNA polymerase II recruitment

scientific article published on April 2004

Adenoviral E1A function through Myc.

scientific article published on January 2009

Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc

scholarly article

An MBoC Favorite: Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes

scientific article published in May 2012

Antagonistic roles for the ubiquitin ligase Asr1 and the ubiquitin-specific protease Ubp3 in subtelomeric gene silencing

scientific article published on 19 January 2016

Chromatin immunoprecipitation to study protein-DNA interactions in budding yeast

scientific article published in January 2006

Combined chemical and genetic approach to inhibit proteolysis by the proteasome.

scientific article published on November 2010

Crashing waves of destruction: the cell cycle and APC(Cdh1) regulation of SCF(Skp2).

scientific article

Damage control: DNA repair, transcription, and the ubiquitin-proteasome system

scientific article published on 09 March 2009

Denaturing Protein Immunoprecipitation from Mammalian Cells ⬇️

scientific article published on 01 January 2007

Denaturing Protein Immunoprecipitation from Yeast ⬇️

scientific article published on 01 January 2007

Detection of Ubiquitylated Proteins in Yeast ⬇️

scientific article published on 01 December 2006

Detection of ubiquitylated proteins in mammalian cells

scientific article published on 01 November 2006

Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction

scientific article published on 05 December 2019

Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core

scientific article published on 07 January 2020

Discovery of Potent 2-Aryl-6,7-dihydro-5H-pyrrolo[1,2-a]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design

scientific article published on 29 June 2018

Discovery of WD Repeat-Containing Protein 5 (WDR5)-MYC Inhibitors Using Fragment-Based Methods and Structure-Based Design

scientific article published on 09 April 2020

Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity

scientific article published on 01 March 2019

Do changes in the c-MYC coding sequence contribute to tumorigenesis?

scientific article published on 30 October 2014

Effectiveness of water soluble poly(L-glutamic acid)-camptothecin conjugate against resistant human lung cancer xenografted in nude mice.

scientific article

Epithelial Cell Organization Suppresses Myc Function by Attenuating Myc Expression ⬇️

scientific article published on May 24, 2011

Evaluation of [131I]iodoerythronitroimidazole as a predictor for the radiosensitizing effect

scientific article published on 01 November 1996

Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants

scientific article

Formation and characterization of cisplatin-loaded poly(benzyl l-glutamate) microspheres for chemoembolization

scientific article published on 01 December 1994

Freeze-Thaw Lysis for Extraction of Proteins from Mammalian Cells ⬇️

scientific article published on 01 December 2006

From silencing to gene expression: real-time analysis in single cells

scientific article

Functional overlap of sequences that activate transcription and signal ubiquitin-mediated proteolysis

scholarly article

Functions of the proteasome on chromatin

scientific article

Gal4 turnover and transcription activation.

scientific article published on October 2009

Gene-specific quantification of nascent transcription following targeted degradation of endogenous proteins in cultured cells

scientific article published on 08 December 2021

HAM: a new epitope-tag for in vivo protein labeling

scientific article

Halogenated analogues of tamoxifen: synthesis, receptor assay, and inhibition of MCF7 cells

scientific article published on July 1, 1992

Histone H2B ubiquitylation and H3 lysine 4 methylation prevent ectopic silencing of euchromatic loci important for the cellular response to heat.

scientific article

How cells use proteolysis to control their growth.

scientific article

How the ubiquitin-proteasome system controls transcription

scientific article

Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication

scientific article

Imaging, biodistribution and therapy potential of halogenated tamoxifen analogues

scientific article published on 01 January 1994

In vivo and in vitro measurement of apoptosis in breast cancer cells using 99mTc-EC-annexin V.

scientific article

Inference of cell cycle-dependent proteolysis by laser scanning cytometry

scientific article

Inhibition of MYC by the SMARCB1 tumor suppressor

scientific article published on 01 May 2019

Integrative network analysis identifies key genes and pathways in the progression of hepatitis C virus induced hepatocellular carcinoma

scientific article published on 8 August 2011

Interaction of Gcn4 with target gene chromatin is modulated by proteasome function

scientific article published on 06 July 2016

Interaction of MYC with host cell factor-1 is mediated by the evolutionarily conserved Myc box IV motif

scientific article published on 2 November 2015

Interaction of the oncoprotein transcription factor MYC with its chromatin cofactor WDR5 is essential for tumor maintenance

scientific article published on 25 November 2019

Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC

scientific article

Letter to the editor. Chemical-genetic strategy for inhibiting proteasome function in Saccharomyces cerevisiae.

scientific article published on 8 December 2011

MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor-1

scientific article published on 08 January 2021

Mammalian MYC Proteins and Cancer

article

Multiple cell-type-specific elements regulate Myc protein stability

scientific article published in May 2004

Multiple interactions of the oncoprotein transcription factor MYC with the SWI/SNF chromatin remodeler

scientific article published on 30 April 2021

Multiple regions of TBP participate in the response to transcriptional activators in vivo

scientific article

Mutations in the carboxy-terminal domain of TBP affect the synthesis of human immunodeficiency virus type 1 full-length and short transcripts similarly

scientific article

Myc-mediated transcriptional repression by recruitment of histone deacetylase.

scientific article published in May 2008

Nondenaturing protein immunoprecipitation from Mammalian cells

scientific article published on 01 January 2007

Old dogs and new tricks: meeting on mechanisms of eukaryotic transcription

scientific article published on March 2002

Polyubiquitylation of histone H2B.

scientific article published on 18 June 2008

Potentiation of ovarian OCa-1 tumor radioresponse by poly (L-glutamic acid)-paclitaxel conjugate

scientific article published on 01 November 2000

Proteasomal ATPases link ubiquitylation of histone H2B to methylation of histone H3.

scientific article published in February 2004

Proteolytic Control of the Oncoprotein Transcription Factor Myc

scientific article published on January 1, 2011

Proteolytic instability and the action of nonclassical transcriptional activators

scientific article

Pulse-Chase Assay for Measuring Protein Stability in Yeast ⬇️

scientific article published on 01 January 2007

Rapid synthesis of 3-[18F]fluoro-1-(2'-nitro-1'-imidazolyl)-2-propanol ([18F]fluoromisonidazole)

scientific article published on 01 March 1994

Regulation of c-myc stability by selective stress conditions and by MEKK1 requires aa 127-189 of c-myc.

scientific article

Renin gene promoter activity in GC cells is regulated by cAMP and thyroid hormone through Pit-1-dependent mechanisms.

scientific article

SCFCdc4-mediated degradation of the Hac1p transcription factor regulates the unfolded protein response in Saccharomyces cerevisiae

scientific article

Selective use of TBP and TFIIB revealed by a TATA-TBP-TFIIB array with altered specificity

scientific article

Similar temporal and spatial recruitment of native 19S and 20S proteasome subunits to transcriptionally active chromatin ⬇️

scientific article published on April 2, 2012

Skp2 regulates Myc protein stability and activity

scientific article published on May 2003

Stable and unstable pools of Myc protein exist in human cells

scientific article published on December 2002

Stable histone adduction by 4-oxo-2-nonenal: a potential link between oxidative stress and epigenetics

scientific article

Synthesis and characterization of branched poly(L-glutamic acid) as a biodegradable drug carrier

scientific article published on January 2004

Synthesis of [99mTc]ethylenedicysteine-colchicine for evaluation of antiangiogenic effect

scientific article published on 01 August 1999

TAFs: guilt by association?

scientific article published on March 1997

Targeting MYC through WDR5

scientific article published on 10 January 2020

Targeting WDR5: A WINning Anti-Cancer Strategy?

scientific article published on 18 July 2019

The F box protein Dsg1/Mdm30 is a transcriptional coactivator that stimulates Gal4 turnover and cotranscriptional mRNA processing

scientific article published on 01 March 2005

The MYC-WDR5 Nexus and Cancer

scientific article

The ability to associate with activation domains in vitro is not required for the TATA box-binding protein to support activated transcription in vivo

scientific article

The proteasome regulatory particle alters the SAGA coactivator to enhance its interactions with transcriptional activators.

scientific article

The proteasome: a utility tool for transcription?

scientific article

The ubiquitin-selective chaperone Cdc48/p97 associates with Ubx3 to modulate monoubiquitylation of histone H2B.

scientific article

Transcriptional activation: risky business

scientific article

Transcriptional and posttranscriptional activation of urokinase plasminogen activator gene expression in metastatic tumor cells

scientific article published on May 1992

Transcriptional control and the ubiquitin-proteasome system

scientific article published on 01 January 2008

Transcriptional regulation: RUPture in the ER

scientific article published on 01 October 2000

Ubiquitin and Proteasomes in Transcription ⬇️

scientific article published on March 8, 2012

WDR5 is a conserved regulator of protein synthesis gene expression

scientific article published on 01 April 2020

Yeast Chromatin Immunoprecipitation (ChIP) Assay

scientific article published on 01 January 2007

Paulina is supported by:

About Paulina

Help