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List of works by Raphael Mechoulam

(+)-Cannabidiol analogues which bind cannabinoid receptors but exert peripheral activity only

scientific article published in December 2004

(-)-Delta9-tetrahydrocannabinol antagonizes the peripheral cannabinoid receptor-mediated inhibition of adenylyl cyclase

scientific article published on April 1996

19-hydroxy-10-isotestosterone ⬇️

scholarly article

2-Arachidonylglycerol, an endogenous cannabinoid, inhibits tumor necrosis factor-alpha production in murine macrophages, and in mice

scientific article

2-arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor

scientific article

5 Towards cannabinoid drugs

6β-Hydroxy-Δ 1 -Tetrahydrocannabinol Synthesis and Biological Activity ⬇️

scientific article published on November 26, 1971

A Total Synthesis of dl-Δ1-Tetrahydrocannabinol, the Active Constituent of Hashish1 ⬇️

scientific article published on 01 July 1965

A cannabinoid anticancer quinone, HU-331, is more potent and less cardiotoxic than doxorubicin: a comparative in vivo study

scientific article

A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells

scientific article

A comparative analysis of the potential of cannabinoids and ondansetron to suppress cisplatin-induced emesis in the Suncus murinus (house musk shrew).

scientific article

A historical overview of chemical research on cannabinoids

scientific article

A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury

scientific article

A new tetrahydrocannabinolic acid ⬇️

scientific article published on 01 June 1969

A nonpsychotropic cannabinoid, HU-211, has cerebroprotective effects after closed head injury in the rat.

scientific article published in January 1993

A novel probe for the cannabinoid receptor ⬇️

scientific article (publication date: 29 May 1992)

A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis

scientific article

A random walk through a cannabis field ⬇️

scientific article published on November 1, 1991

A repeated test procedure to assess onset and duration of the cue properties of (-) delta 9-THC, (-) delta 8-THC-DMH and (+) delta 8-THC.

scientific article published in January 1981

A study investigating the acute dose-response effects of 13 mg and 17 mg Delta 9- tetrahydrocannabinol on cognitive-motor skills, subjective and autonomic measures in regular users of marijuana

scientific article published in June 2008

Activation of cannabinoid receptors decreases the area of ischemic myocardial necrosis

scientific article published in February 2002

Activity of novel aminocannabinoids in baboons

scientific article published on 01 October 1984

Acute naloxone-precipitated morphine withdrawal elicits nausea-like somatic behaviors in rats in a manner suppressed by N-oleoylglycine

scientific article published on 11 November 2019

Acute oral cannabidiolic acid methyl ester reduces depression-like behavior in two genetic animal models of depression

scientific article published on 31 May 2018

Administration of 2-arachidonoylglycerol ameliorates both acute and chronic experimental autoimmune encephalomyelitis

scientific article published on 13 March 2011

Altered dopamine D3 receptor gene expression in MAM model of schizophrenia is reversed by peripubertal cannabidiol treatment

scientific article published on 28 April 2020

An endogenous cannabinoid (2-AG) is neuroprotective after brain injury

scientific article

An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity

scientific article published on July 1998

An evaluation of the anti-hyperalgesic effects of cannabidiolic acid-methyl ester in a preclinical model of peripheral neuropathic pain

scientific article published on 24 January 2020

Anandamide (arachidonylethanolamide), a brain cannabinoid receptor agonist, reduces sperm fertilizing capacity in sea urchins by inhibiting the acrosome reaction

scientific article published on August 1994

Anandamide alters the membrane properties, halts the cell division and prevents drug efflux in multidrug resistant Staphylococcus aureus

scientific article published on 22 April 2021

Anandamide may mediate sleep induction

scientific article

Anandamide prevents the adhesion of filamentous Candida albicans to cervical epithelial cells

scientific article published on 13 August 2020

Anandamide, a brain endogenous compound, interacts specifically with cannabinoid receptors and inhibits adenylate cyclase

scientific article published in July 1993

Anti-inflammatory effects of the cannabidiol derivative dimethylheptyl-cannabidiol - studies in BV-2 microglia and encephalitogenic T cells

scientific article

Anticonvulsant and neurotoxic effects of tetrahydrocannabinol stereoisomers

scientific article published on 01 January 1987

Anticonvulsant effects of the (-) and (+)isomers of cannabidiol and their dimethylheptyl homologs

scientific article

Antimicrobial potential of endocannabinoid and endocannabinoid-like compounds against methicillin-resistant Staphylococcus aureus

scientific article published in Scientific Reports

Antinociceptive effects of HUF-101, a fluorinated cannabidiol derivative.

scientific article

Antioxidant properties of the vasoactive endocannabinoid, 2-arachidonoyl glycerol (2-AG).

scientific article published in January 2003

Antipsychotic effect of cannabidiol.

scientific article published in October 1995

Anxiolytic effect of cannabidiol derivatives in the elevated plus-maze.

scientific article published in January 1994

Are the endocannabinoid-like compounds N-acyl aminoacids neuroprotective after traumatic brain injury?

scientific article published on 13 November 2015

Attenuation of allergic contact dermatitis through the endocannabinoid system

scientific article

Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs ⬇️

scientific article published on November 1, 1991

Benzoxocin and benzoxonin derivatives. Novel groups of terpenophenols with central nervous system activity. Correction ⬇️

scientific article (publication date: September 1975)

Beyond THC and Endocannabinoids

scientific article published on 03 October 2019

Bioactive lipids ALIAmides differentially modulate inflammatory responses of distinct subsets of primary human T lymphocytes

scientific article published on 07 June 2018

Biphasic effects of anandamide

scientific article

Blockade of 45Ca2+ influx through the N-methyl-D-aspartate receptor ion channel by the non-psychoactive cannabinoid HU-211.

scientific article published in September 1993

Blowing away the smokescreen

scientific article published in Nature

Boron triflouride etherate on alimina - a modified Lewis acid reagent

Boswellia resin: from religious ceremonies to medical uses; a review of in-vitro, in-vivo and clinical trials

scientific article published on October 2009

Brain imaging study of the acute effects of Delta9-tetrahydrocannabinol (THC) on attention and motor coordination in regular users of marijuana

scientific article published on 26 September 2007

CB1 cannabinoid receptors are involved in neuroprotection via NF-kappa B inhibition

scientific article

CB1 cannabinoid receptors mediate endochondral skeletal growth attenuation by Δ9-tetrahydrocannabinol

scientific article published in January 2015

CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency

scientific article published on 29 June 2015

CB2 cannabinoid receptor targets mitogenic Gi protein–cyclin D1 axis in osteoblasts ⬇️

scientific article published on February 1, 2011

Cannabidiol

Cannabidiol Partially Blocks the Excessive Sleepiness in Hypocretindeficient Rats: Preliminary Data

scientific article published on 01 January 2019

Cannabidiol Protects against Doxorubicin-Induced Cardiomyopathy by Modulating Mitochondrial Function and Biogenesis

scientific article published on 6 January 2015

Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation

scientific article

Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation.

scientific article published on 27 May 2009

Cannabidiol and other cannabinoids reduce microglial activation in vitro and in vivo: relevance to Alzheimer's disease

scientific article

Cannabidiol arrests onset of autoimmune diabetes in NOD mice

scientific article published on 17 July 2007

Cannabidiol attenuates alcohol-induced liver steatosis, metabolic dysregulation, inflammation and neutrophil-mediated injury

scientific article

Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy

scientific article

Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?

scientific article published on February 2013

Cannabidiol for the Prevention of Graft-versus-Host-Disease after Allogeneic Hematopoietic Cell Transplantation: Results of a Phase II Study

scientific article published on 30 May 2015

Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice

scientific article

Cannabidiol limits Tcell-mediated chronic autoimmune myocarditis: implications to autoimmune disorders and organ transplantation

scientific article published on 08 January 2016

Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test

scientific article published on 11 October 2018

Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death

scientific article

Cannabidiol protects oligodendrocyte progenitor cells from inflammation-induced apoptosis by attenuating endoplasmic reticulum stress

scientific article published on 28 June 2012

Cannabidiol reduced the striatal atrophy caused 3-nitropropionic acid in vivo by mechanisms independent of the activation of cannabinoid, vanilloid TRPV1 and adenosine A2A receptors

scientific article published on 2 August 2007

Cannabidiol, a Major Non-Psychotropic Cannabis Constituent Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts

scientific article

Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats

scientific article published on 10 July 2006

Cannabidiol, a non-psychoactive component of cannabis and its synthetic dimethylheptyl homolog suppress nausea in an experimental model with rats

scientific article published in April 2002

Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus

scientific article

Cannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury

scientific article published on 21 September 2007

Cannabidiol--recent advances

scientific article

Cannabidiol: an overview of some chemical and pharmacological aspects. Part I: chemical aspects

scientific article

Cannabidiol: an overview of some pharmacological aspects

scientific article

Cannabidiolic acid methyl ester, a stable synthetic analogue of cannabidiolic acid, can produce 5-HT1A receptor-mediated suppression of nausea and anxiety in rats

scientific article

Cannabimimetic activity (delta 1-THC cue) of cannabidiol monomethyl ether and two stereoisomeric hexahydrocannabinols in rats and pigeons.

scientific article published in August 1986

Cannabimimetic activity of novel enantiomeric, benzofuran cannabinoids

scientific article published on 01 March 1990

Cannabinoid 2 (CB2) receptor agonism reduces lithium chloride-induced vomiting in Suncus murinus and nausea-induced conditioned gaping in rats

scientific article published on 2 June 2016

Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: relevance for Huntington's disease.

scientific article published on August 2009

Cannabinoid agonists and antagonists modulate lithium-induced conditioned gaping in rats ⬇️

scientific article published on April 1, 2003

Cannabinoid enantiomer action on the cytoarchitecture

scientific article published on 01 February 1996

Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines

scientific article

Cannabinoids ameliorate cerebral dysfunction following liver failure via AMP-activated protein kinase

scientific article published on 12 April 2007

Cannabinoids and brain injury: therapeutic implications

scientific article published in February 2002

Cannabinoids and capsaicin improve liver function following thioacetamide-induced acute injury in mice

scientific article

Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes

scientific article

Cannabinoids in health and disease

scientific article

Cannabinoids induce glioma stem-like cell differentiation and inhibit gliomagenesis

scientific article published on 2 January 2007

Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease

scientific article

Cannabinoids: between neuroprotection and neurotoxicity

scientific article

Cannabinoids: receptors, endogenous ligands and a newly synthesized antagonist

scientific article published on 01 January 1996

Cannabinol derivatives: binding to cannabinoid receptors and inhibition of adenylylcyclase

scientific article

Cannabinol: a rapidly formed metabolite of delta-1- and delta-6-tetrahydrocannabinol

scientific article published on May 15, 1975

Cannabinomimetic behavioral effects of and adenylate cyclase inhibition by two new endogenous anandamides

scientific article published in December 1995

Cannabis - the Israeli perspective

scientific article published on 30 September 2015

Cannabis and alcohol--a close friendship

scientific article

Cannabis--a valuable drug that deserves better treatment

scientific article published on February 2012

Capsaicin affects brain function in a model of hepatic encephalopathy associated with fulminant hepatic failure in mice

scientific article published on 18 September 2009

Carbachol, an acetylcholine receptor agonist, enhances production in rat aorta of 2-arachidonoyl glycerol, a hypotensive endocannabinoid

scientific article published on 01 November 1998

Characterization of the hypothermic effect of the synthetic cannabinoid HU-210 in the rat. Relation to the adrenergic system and endogenous pyrogens

scientific article published on 01 February 1995

Chemical basis of hashish activity

scientific article published in August 1970

Chemical synthesis and biological occurrence of carboxylic acid metabolites of delta1(6)-tetrahydrocannabinol

scientific article

Chronic administration of cannabidiol to healthy volunteers and epileptic patients

scientific article published on 01 January 1980

Comparative Evaluation of Combinatory Interaction between Endocannabinoid System Compounds and Poly-L-lysine against Streptococcus mutans Growth and Biofilm Formation

scientific article published on 31 January 2020

Comparison of the enzymatic stability and intraocular pressure effects of 2-arachidonylglycerol and noladin ether, a novel putative endocannabinoid

scientific article (publication date: October 2002)

Conversation with Raphael Mechoulam

scientific article published in June 2007

Correction: Fluorinated Cannabidiol Derivatives: Enhancement of Activity in Mice Models Predictive of Anxiolytic, Antidepressant and Antipsychotic Effects

scientific article published on 25 August 2016

Critical role of the endogenous cannabinoid system in mouse pup suckling and growth

scientific article

Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectant

scientific article published on February 1997

Delta 6-tetrahydrocannabinol-7-oic acid, a urinary delta 6-THC metabolite: isolation and synthesis

scientific article published on 01 October 1973

Delta 9-tetrahydrocannabinol inhibits cell cycle progression by downregulation of E2F1 in human glioblastoma multiforme cells ⬇️

scientific article

Delta-9-tetrahydrocannabinol and cannabidiol, but not ondansetron, interfere with conditioned retching reactions elicited by a lithium-paired context in Suncus murinus: An animal model of anticipatory nausea and vomiting

scientific article

Derivatives of Dexanabinol. I. Water-soluble salts of glycinate esters

scientific article published on 01 January 1996

Derivatives of dexanabinol. II. Salts of amino acid esters containing tertiary and quaternary heterocyclic nitrogen with increased water-solubility

scientific article published on 01 March 1996

Developmental aspects of anandamide: ontogeny of response and prenatal exposure

scientific article published on February 1996

Dexanabinol (HU-211): A nonpsychotropic cannabinoid with neuroprotective properties

Differential response to acute and repeated stress in cannabinoid CB1 receptor knockout newborn and adult mice

scientific article

Discovery and characterization of endogenous cannabinoids

scientific article

Discovery of endocannabinoids and some random thoughts on their possible roles in neuroprotection and aggression

scientific article

Discriminative stimulus effects and receptor binding of enantiomeric pairs of cannabinoids in rats and pigeons; a comparison.

scientific article published in February 1993

Discriminative stimulus- and open-field effects of the enantiomers of 11-hydroxy-delta-8-tetrahydrocannabinol in pigeons and gerbils.

scientific article published in January 1994

Dominant negative DISC1 mutant mice display specific social behaviour deficits and aberration in BDNF and cannabinoid receptor expression

scientific article

Drug-induced hypothermia reduces ischemic damage: effects of the cannabinoid HU-210.

scientific article

Early medical use of cannabis

scientific article published in May 1993

Early phytocannabinoid chemistry to endocannabinoids and beyond

scientific article published on 15 October 2014

Effect of cannabinoids on lithium-induced vomiting in the Suncus murinus (house musk shrew).

scientific article published on 10 September 2003

Effect of low doses of delta9-tetrahydrocannabinol and cannabidiol on the extinction of cocaine-induced and amphetamine-induced conditioned place preference learning in rats

scientific article

Effect of prior foot shock stress and Δ9-tetrahydrocannabinol, cannabidiolic acid, and cannabidiol on anxiety-like responding in the light-dark emergence test in rats

scientific article published on 20 April 2017

Effect of stereospecific cannabinoids on the immune system

scientific article published on January 1991

Effect of the brain constituent anandamide, a cannabinoid receptor agonist, on the hypothalamo-pituitary-adrenal axis in the rat.

scientific article

Effect of the synthetic cannabinoid HU-210 on quorum sensing and on the production of quorum sensing-mediated virulence factors by Vibrio harveyi

scientific article published on 12 August 2015

Effects of THC on driving performance, physiological state and subjective feelings relative to alcohol

scientific article published on 26 November 2007

Effects of cannabidiol in males and females in two different rat models of depression

scientific article published on 17 December 2018

Effects of cannabidiol on behavioral seizures caused by convulsant drugs or current in mice

scientific article published on 01 September 1982

Effects of cannabinoids on lithium-induced conditioned rejection reactions in a rat model of nausea

scientific article published on 15 January 2003

Effects of the endocannabinoid noladin ether on body weight, food consumption, locomotor activity, and cognitive index in mice

scientific article

Effects of two endogenous fatty acid ethanolamides on mouse vasa deferentia

scientific article

Effects on sleep and dopamine levels of microdialysis perfusion of cannabidiol into the lateral hypothalamus of rats

scientific article published on 22 January 2011

Enantiomeric cannabidiol derivatives: synthesis and binding to cannabinoid receptors

scientific article

Enantiomeric cannabinoids: stereospecificity of psychotropic activity ⬇️

scientific article published on September 15, 1988

Endocannabinoid signaling at the periphery: 50 years after THC.

scientific article published on 18 March 2015

Endocannabinoid signaling in neurotoxicity and neuroprotection

scientific article published on 5 December 2009

Endocannabinoids

scholarly article from 1998

Endocannabinoids affect neurological and cognitive function in thioacetamide-induced hepatic encephalopathy in mice

scientific article published on 15 August 2005

Endocannabinoids and traumatic brain injury

scientific article

Endocannabinoids as positive or negative factors in hematopoietic cell migration and differentiation

scientific article

Endocannabinoids in liver disease and hepatic encephalopathy

scientific article published on January 2008

Endocannabinoids, feeding and suckling--from our perspective

scientific article

Endogenous cannabinoid ligands--chemical and biological studies

scientific article published on September 1996

Endogenous cannabinoid ligands.

scientific article published on January 1996

Endogenous cannabinoids improve myocardial resistance to arrhythmogenic effects of coronary occlusion and reperfusion: a possible mechanism.

scientific article published in February 2002

Endothelial-mediated regulation of cerebral microcirculation.

scientific article

Epidemiological characteristics, safety and efficacy of medical cannabis in the elderly

scientific article published in February 2018

Estrogens in insects

article by Raphael Mechoulam et al published September 1984 in Cellular and Molecular Life Sciences

Evaluation of repeated or acute treatment with cannabidiol (CBD), cannabidiolic acid (CBDA) or CBDA methyl ester (HU-580) on nausea and/or vomiting in rats and shrews

scientific article published on 02 June 2020

Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties

scientific article published on 28 December 2006

Evidence that (-)-7-hydroxy-4'-dimethylheptyl-cannabidiol activates a non-CB(1), non-CB(2), non-TRPV1 target in the mouse vas deferens

scientific article published on 19 March 2005

Fluorinated Cannabidiol Derivatives: Enhancement of Activity in Mice Models Predictive of Anxiolytic, Antidepressant and Antipsychotic Effects.

scientific article

From gan-zi-gun-nu to anandamide and 2-arachidonoylglycerol: the ongoing story of cannabis

scientific article

Gamma-irradiation enhances apoptosis induced by cannabidiol, a non-psychotropic cannabinoid, in cultured HL-60 myeloblastic leukemia cells

scientific article published on October 2003

HDAC1 and HDAC3 underlie dynamic H3K9 acetylation during embryonic neurogenesis and in schizophrenia-like animals.

scientific article published on 16 March 2017

HU-308: a specific agonist for CB(2), a peripheral cannabinoid receptor

scientific article

HU-331, a novel cannabinoid-based anticancer topoisomerase II inhibitor

scientific article

HU-444, a Novel, Potent Anti-Inflammatory, Nonpsychotropic Cannabinoid

scientific article

HU-446 and HU-465, Derivatives of the Non-psychoactive Cannabinoid Cannabidiol, Decrease the Activation of Encephalitogenic T Cells.

scientific article published on 11 August 2015

HU-671, a Novel Oleoyl Serine Derivative, Exhibits Enhanced Efficacy in Reversing Ovariectomy-Induced Osteoporosis and Bone Marrow Adiposity

scientific article published on 16 October 2019

Hashish—VII

Hippocampal cannabinoid-1 receptor upregulation upon endothelin-B receptor deficiency: a neuroprotective substitution effect?

scientific article

Human brain capillary endothelium: 2-arachidonoglycerol (endocannabinoid) interacts with endothelin-1

scientific article published on 01 August 2000

Human brain endothelium: coexpression and function of vanilloid and endocannabinoid receptors

scientific article published in December 2004

Human pharmacology of 1S and 1R enantiomers of delta-3-tetrahydrocannabinol

scientific article published in January 1987

Identification of 5α-Androstane-3α, 17β-diol as a Principal Metabolite of Pregnenolone in Rat Ovary at Onset of Puberty ⬇️

scientific article published on November 28, 1970

Identification of a C-glucuronide of delta6- tetrahydrocannabinol as a mouse liver conjugate in vivo

scientific article published on June 23, 1978

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors ⬇️

scientific article published on June 29, 1995

Identification through synthesis of an active delta-1(6)-tetrahydrocannabinol metabolite

article by Z Ben-Zvi et al published 1 June 1970 in Journal of the American Chemical Society

In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma

scientific article published on 16 March 2016

Incensole acetate, a novel anti-inflammatory compound isolated from Boswellia resin, inhibits nuclear factor-kappa B activation

scientific article

Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brain

scientific article

Incensole acetate: a novel neuroprotective agent isolated from Boswellia carterii.

scientific article

Increase of the heart arrhythmogenic resistance and decrease of the myocardial necrosis zone during activation of cannabinoid receptors

scientific article

Inhibition of cisplatin-induced emesis in the pigeon by a non-psychotropic synthetic cannabinoid

scientific article published on 01 October 1989

Inhibition of human neutrophil chemotaxis by endogenous cannabinoids and phytocannabinoids: evidence for a site distinct from CB1 and CB2.

scientific article

Inhibition of monoacylglycerol lipase attenuates vomiting in Suncus murinus and 2-arachidonoyl glycerol attenuates nausea in rats

scientific article

Inhibitory effects of certain enantiomeric cannabinoids in the mouse vas deferens and the myenteric plexus preparation of guinea-pig small intestine ⬇️

scientific article published on April 1, 1992

Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews.

scientific article published on 18 January 2011

International Cannabis Research Society meeting summary, Keystone, CO (June 19-20, 1992).

scientific article published in February 1993

International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CB₂

scientific article

International Union of Pharmacology. XXVII. Classification of cannabinoid receptors

scientific article (publication date: June 2002)

Interview with Prof. Raphael Mechoulam, codiscoverer of THC.. Interview by Stanley Einstein

scientific article published in April 1986

Intraperirhinal cortex administration of the synthetic cannabinoid, HU210, disrupts object recognition memory in rats

scientific article

Involvement of central and peripheral cannabinoid receptors in the regulation of heart resistance to arrhythmogenic effects of epinephrine

scientific article

Involvement of neuronal cannabinoid receptor CB1 in regulation of bone mass and bone remodeling.

scientific article published on 13 June 2006

Is lipid signaling through cannabinoid 2 receptors part of a protective system?

scientific article

Isolation and structure of .DELTA.+- tetrahydrocannabinol and other neutral cannabinoids from hashish

scientific article published on 01 January 1971

Isolation and structure of a brain constituent that binds to the cannabinoid receptor

scientific article (publication date: 18 December 1992)

Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish

article by Y. Gaoni & Raphael Mechoulam published April 1964 in Journal of the American Chemical Society

Isotope effect studies on the dehydrogenation of delta 1-tetrahydrocannabinol in the rat

scientific article published on August 15, 1977

Lipids in neural function: modulation of behavior by oral administration of endocannabinoids found in foods

scientific article

Low dose anandamide affects food intake, cognitive function, neurotransmitter and corticosterone levels in diet-restricted mice.

scientific article published in March 2000

Low doses of anandamides inhibit pharmacological effects of delta 9-tetrahydrocannabinol

scientific article published on 01 February 1995

Magel2 Modulates Bone Remodeling and Mass in Prader-Willi Syndrome by Affecting Oleoyl Serine Levels and Activity

scientific article published on 22 October 2018

Metabolism of 7-hydroxy- 1(6)-tetrahydrocannabinol in the rabbit

scientific article published on 01 May 1973

Metabolism of Δ1(6)-Tetrahydro-cannabinol, an Active Marihuana Constituent ⬇️

scientific article published on 01 January 1970

Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: evidence for a "CB3" receptor

scientific article

Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide

scientific article

Motor effects of the non-psychotropic phytocannabinoid cannabidiol that are mediated by 5-HT1A receptors

scientific article published on 4 August 2013

Multiple sclerosis may disrupt endocannabinoid brain protection mechanism

scholarly article

N-Acyl amino acids and their impact on biological processes

scientific article published on 21 April 2014

N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice.

scientific article published on 19 March 2018

N-arachidonoyl L-serine, an endocannabinoid-like brain constituent with vasodilatory properties

scientific article

N-arachidonoyl-L-serine (AraS) possesses proneurogenic properties in vitro and in vivo after traumatic brain injury

scientific article published on 22 May 2013

N-arachidonoyl-L-serine is neuroprotective after traumatic brain injury by reducing apoptosis

scientific article

Neuroscience. Stout guards of the central nervous system

scientific article published in October 2003

Noladin ether, a putative novel endocannabinoid: inactivation mechanisms and a sensitive method for its quantification in rat tissues

scientific article (publication date: 27 February 2002)

Non-psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation

scientific article

Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb

scientific article

Nonpsychotropic cannabinoid acts as a functional N-methyl-D-aspartate receptor blocker

scientific article

Nonpsychotropic synthetic cannabinoids as therapeutic agents

scientific article published on January 1, 1991

Novel natural and synthetic ligands of the endocannabinoid system

scientific article

Oleoyl alanine (HU595): a stable monomethylated oleoyl glycine interferes with acute naloxone precipitated morphine withdrawal in male rats

scientific article published on 16 June 2020

Oleoyl glycine: interference with the aversive effects of acute naloxone-precipitated MWD, but not morphine reward, in male Sprague-Dawley rats

scientific article published on 16 April 2019

Oleoyl serine, an endogenous N-acyl amide, modulates bone remodeling and mass

scientific article

Omega-3 N-acylethanolamines are endogenously synthesised from omega-3 fatty acids in different human prostate and breast cancer cell lines

scientific article published on 12 October 2011

Ontogenetic development of the response to anandamide and delta 9-tetrahydrocannabinol in mice

scientific article published in August 1996

Palmitoyl Serine: An Endogenous Neuroprotective Endocannabinoid-Like Entity After Traumatic Brain Injury

scientific article

Peering through the smoke

scientific article published in Nature

Peripheral cannabinoid receptor, CB2, regulates bone mass

scientific article

Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia

scientific article published on 26 November 2018

Pharmacological activity of the cannabinoid receptor agonist, anandamide, a brain constituent

scientific article published in February 1993

Physiology. A hunger for cannabinoids

scientific article published in April 2001

Plant cannabinoids: a neglected pharmacological treasure trove

scientific article published in December 2005

Potential combinations of endocannabinoid/endocannabinoid-like compounds and antibiotics against methicillin-resistant Staphylococcus aureus

scientific article published on 15 April 2020

Preliminary, open-label, pilot study of add-on oral Δ9-tetrahydrocannabinol in chronic post-traumatic stress disorder

scientific article

Presence of functional cannabinoid receptors in human endocrine pancreas

scientific article

Prohedonic Effect of Cannabidiol in a Rat Model of Depression

scientific article published on 25 March 2016

Prospective analysis of safety and efficacy of medical cannabis in large unselected population of patients with cancer

scientific article published on 01 March 2018

Prospects for Creation of Cardioprotective Drugs Based on Cannabinoid Receptor Agonists.

scientific article

Prospects for cannabinoid therapies in basal ganglia disorders

scientific article published on August 2011

Protection against septic shock and suppression of tumor necrosis factor alpha and nitric oxide production by dexanabinol (HU-211), a nonpsychotropic cannabinoid.

scientific article published on November 1997

Protective Effects of N-Oleoylglycine in a Mouse Model of Mild Traumatic Brain Injury

scientific article published on 02 April 2020

Real life Experience of Medical Cannabis Treatment in Autism: Analysis of Safety and Efficacy

scientific article published in Scientific Reports

Recent Advances in the Chemistry of Hashish ⬇️

scientific article

Reduction of hippocampal acetylcholine turnover in rats treated with (-)-delta 8-tetrahydrocannabinol and its 1',2'-dimethyl-heptyl homolog

scientific article published on 01 August 1980

Repeated stimulation of D1 dopamine receptors enhances (-)-11-hydroxy-delta 8-tetrahydrocannabinol-dimethyl-heptyl-induced catalepsy in male rats

scientific article published on 01 March 1994

Reply

scientific article (publication date: December 2004)

Role of CB2 Receptor in the Recovery of Mice after Traumatic Brain Injury

scientific article published on 07 February 2019

Search for endogenous ligands of the cannabinoid receptor

scientific article published on October 1994

Separation of the discriminative stimulus effects of stereoisomers of delta 2- and delta 3-tetrahydrocannabinols in pigeons.

scientific article published in November 1988

Short-term fasting and prolonged semistarvation have opposite effects on 2-AG levels in mouse brain

scientific article published in September 2003

Skeletal anabolic activity of cannabinoid receptor agonists

scientific article published in May 2009

Skeletal lipidomics: regulation of bone metabolism by fatty acid amide family

scientific article

Sleep and neurochemical modulation by cannabidiolic acid methyl ester in rats

scientific article published on 12 December 2019

Stereochemical effects of 11-OH-delta 8-THC-dimethylheptyl in mice and dogs

scientific article

Stereochemical effects of 11-OH-delta 8-tetrahydrocannabinol-dimethylheptyl to inhibit adenylate cyclase and bind to the cannabinoid receptor

scientific article

Stereochemical requirements for cannabimimetic activity

scientific article published on January 1987

Stereochemical requirements for cannabinoid activity

scientific article published on 01 October 1980

Stereoelectronic factor in the chloranil dehydrogenation of cannabinoids. Total synthesis of dl-cannabichromene

scientific article published on 01 April 1968

Stereospecific effects of (-)- and (+)-7-hydroxy-delta-6-tetrahydrocannabinol-dimethylheptyl on the immune system of mice

scientific article published on 01 January 1989

Stereospecific synthesis of (-)-.DELTA.1- and (-)-.DELTA.1(6)-tetrahydrocannabinols ⬇️

scientific article published on 01 August 1967

Stereospecifically labeled delta1(6)-tetrahydrocannabinol

scientific article published on 01 April 1968

Stereospecificity of the discriminative stimulus functions of the dimethylheptyl homologs of 11-hydroxy-delta 8-tetrahydrocannabinol in rats and pigeons

scientific article

Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor

scientific article

Structure-activity relationships in the tetrahydrocannabinol series. Modifications on the aromatic ring and it the side-chain.

scientific article

Structure-activity relationships of pyrroleamidine antiviral antibiotics. 1. Modifications of the alkylamidine side chain ⬇️

scientific article published on November 1, 1979

Structure-anticonvulsant activity relationships of cannabidiol analogs

scientific article published on 01 January 1987

Structure–activity relationships of pyrrole amidine antiviral antibiotics III: Preparation of distamycin and congocidine derivatives based on 2,5-disubstituted pyrroles ⬇️

scientific article published on 01 November 1980

Suppression of experimental autoimmune encephalomyelitis by cannabinoids

scientific article published on 01 November 1994

Suppression of neuropathic pain behavior in rats by a non-psychotropic synthetic cannabinoid with NMDA receptor-blocking properties

scientific article

Syntheses of 1 -tetrahydrocannabinol and related cannabinoids

scientific article published on 01 August 1972

Synthesis and antitumor activity of quinonoid derivatives of cannabinoids

scientific article published on July 2004

Synthesis and biological activity of five tetrahydrocannabinol metabolites ⬇️

scientific article published on 01 November 1972

Synthesis and enzymatic formation of a C-glucuronide of delta6-tetrahydrocannabinol

scientific article published on September 14, 1977

Synthesis and psychotropic activity of side-chain hydroxylated delta6-tetrahydrocannabinol metabolites

scientific article published on January 1, 1979

Synthesis of a potential urinary tetrahydrocannabinol metabolite

scientific article published on 01 June 1972

Synthetic nonpsychotropic cannabinoids with potent antiinflammatory, analgesic, and leukocyte antiadhesion activities

scientific article published on August 21, 1992

Tetrahydrocannabinol and endocannabinoids in feeding and appetite

scientific article

The CB(2) cannabinoid receptor controls myeloid progenitor trafficking: involvement in the pathogenesis of an animal model of multiple sclerosis.

scientific article

The CB1 cannabinoid receptor agonist, HU-210, reduces levodopa-induced rotations in 6-hydroxydopamine-lesioned rats

scientific article published on August 2003

The Endocannabinoid System: A Look Back and Ahead

scientific article published in January 2015

The absolute configuration of δ1-tetrahydrocannabinol, the major active constituent of hashish ⬇️

scientific article published on 01 March 1967

The anti-nausea effects of CB1 agonists are mediated by an action at the visceral insular cortex

scientific article

The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling.

scientific article

The cannabinoids: an overview. Therapeutic implications in vomiting and nausea after cancer chemotherapy, in appetite promotion, in multiple sclerosis and in neuroprotection

scientific article

The effect of cannabidiol and URB597 on conditioned gaping (a model of nausea) elicited by a lithium-paired context in the rat.

scientific article published on 9 November 2007

The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines

scientific article published on 20 December 2005

The endocannabinoid system and the brain

scientific article published on 12 July 2012

The non-psychotropic cannabinoid (+)-(3S,4S)-7-hydroxy-delta 6- tetrahydrocannabinol 1,1-dimethylheptyl (HU-211) attenuates N-methyl-D-aspartate receptor-mediated neurotoxicity in primary cultures of rat forebrain

scientific article

The non-psychotropic cannabinoid (+)-(3S,4S)-7-hydroxy-Δ6-tetrahydrocannabinol 1,1-dimethylheptyl (HU-211) attenuates receptor-mediated neurotoxicity in primary cultures of rat forebrain

scientific article (publication date: November 1993)

The nonpsychoactive Cannabis constituent cannabidiol is a wake-inducing agent

scientific article

The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis

scientific article

The ovulation blocking effect of cannabinoids: Structure-activity relationships ⬇️

scientific article published on 01 January 1980

The peripheral cannabinoid receptor: adenylate cyclase inhibition and G protein coupling

scientific journal article

The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice

scientific article published in July 1994

The promise of advances in the field of endocannabinoids.

scientific article

The sleep inducing factor oleamide is produced by mouse neuroblastoma cells

scientific article published in October 1997

The synthetic cannabinoid HU-210 attenuates neural damage in diabetic mice and hyperglycemic pheochromocytoma PC12 cells

scientific article published on 21 May 2007

Therapeutic opportunities through modulation of the endocannabinoid system.

scientific article

Todd's achievement

scientific article published in April 1997

Total synthesis of cannabidiol and delta1-tetrahydrocannabinol metabolites

scientific article published on 01 January 1976

Toward an anandamide transporter

scientific article

Towards a better cannabis drug

scientific article published on December 2013

Towards cannabinoid drugs--revisited.

scientific article

Towards cannabinoid drugs.

scientific article

Trick or treat from food endocannabinoids?

scientific article

Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor

scientific article

Up-regulation of the endocannabinoid system in the uterus of leptin knockout (ob/ob) mice and implications for fertility

scientific article

[Role of receptor transactivation in the cardioprotective effects of preconditioning and postconditioning].

scientific article

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