List of works by Namiki Izumi

109th Scientific Meeting of the Japanese Society of Internal Medicine: educational lecture: 7. Cutting edge of the treatment for viral hepatitis

scientific article published in September 2012

2011 Japanese Society for Dialysis Therapy guidelines for the treatment of hepatitis C virus infection in dialysis patients

scientific article published on 11 June 2012

96 weeks treatment of tenofovir alafenamide vs. tenofovir disoproxil fumarate for hepatitis B virus infection.

scientific article

A Randomized, Double-Blind, Placebo-Controlled, Phase 3 of Tivantinib in Japanese Patients with MET-high Hepatocellular Carcinoma

scientific article published on 27 July 2020

A case of advanced gastric cancer acquired long-term response two years or more by treatment with oral anticancer drug TS-1

scientific article published in December 2004

A case of primary leiomyoma of the liver in a patient without evidence of immunosuppression

scientific article published on 01 September 2002

A case of systemic amyloidosis with cholangiectasis diagnosed by liver biopsy

scientific article published on June 2013

A comparison of the exponential decay slope between PEG-IFN alfa-2b/ribavirin and IFN alfa-2b/ribavirin combination therapy in patients with chronic hepatitis C genotype 1b infection and a high viral load

scientific article published on January 2004

A comparison of the surgical outcomes among patients with HBV-positive, HCV-positive, and non-B non-C hepatocellular carcinoma: a nationwide study of 11,950 patients

scientific article published on March 2015

A multicenter survey of re-treatment with pegylated interferon plus ribavirin combination therapy for patients with chronic hepatitis C in Japan

scientific article published in January 2013

A predictive model of response to peginterferon ribavirin in chronic hepatitis C using classification and regression tree analysis

scientific article published on 11 January 2010

A randomized controlled trial of lusutrombopag in Japanese patients with chronic liver disease undergoing radiofrequency ablation

scientific article published on 13 August 2018

A randomized trial of 24 versus 48 weeks of peginterferon α-2a in patients infected with chronic hepatitis C virus genotype 2 or low viral load genotype 1: a multicenter national study in Japan

scientific article published on 22 May 2009

A triple combination therapy of simeprevir (SM), pegylated-interferon and ribavirin (PR) with chronic hepatitis C virus genotype 1 infection

scientific article published on December 2015

A triple combination therapy of simeprevir, pegylated-interferon and ribavirin with chronic hepatitis C virus genotype 1 infection

scientific article published on February 2015

Accumulation of refractory factors for pegylated interferon plus ribavirin therapy in older female patients with chronic hepatitis C.

scientific article published on 7 October 2010

Age and total ribavirin dose are independent predictors of relapse after interferon therapy in chronic hepatitis C revealed by data mining analysis

scientific article

Alpha-fetoprotein and des-gamma-carboxy-prothrombin at twenty-four weeks after interferon-based therapy predict hepatocellular carcinoma development

scientific article

Amino acid substitutions in PKR-eIF2 phosphorylation homology domain (PePHD) of hepatitis C virus E2 protein in genotype 2a/2b and 1b in Japan and interferon efficacy

scientific article published in August 2003

Analysis of Patient Outcome after Non-curative Resection for Hepatocellular Carcinoma Using Nationwide Survey Data in Japan

scientific article published on 26 October 2020

Analysis of replicating hepatitis C virus quasispecies in hepatocellular carcinoma tissues

scientific article published in July 2004

Antithrombin III for portal vein thrombosis in patients with liver disease: A randomized, double-blind, controlled trial

scientific article published on 30 June 2017

Antiviral effect of carnitine for chronic hepatitis or liver cirrhosis patients

scientific article published on December 2015

Assessment of Kupffer cells by ferumoxides-enhanced MR imaging is beneficial for diagnosis of hepatocellular carcinoma: comparison of pathological diagnosis and perfusion patterns assessed by CT hepatic arteriography and CT arterioportography ⬇️

scientific article published on 01 November 2003

Association of IL28B variants with response to pegylated-interferon alpha plus ribavirin combination therapy reveals intersubgenotypic differences between genotypes 2a and 2b.

scientific article

Association of gene expression involving innate immunity and genetic variation in interleukin 28B with antiviral response

scientific article published on 29 November 2011

Association of serum IFN-λ3 with inflammatory and fibrosis markers in patients with chronic hepatitis C virus infection.

scientific article published on 14 December 2014

Avatrombopag Before Procedures Reduces Need for Platelet Transfusion in Patients With Chronic Liver Disease and Thrombocytopenia

scientific article published on 17 May 2018

B-Mode Ultrasonography versus Contrast-Enhanced Ultrasonography for Surveillance of Hepatocellular Carcinoma: A Prospective Multicenter Randomized Controlled Trial

scientific article published on 06 June 2019

Baseline and Early Predictors of Good Patient Candidates for Second-Line after Sorafenib Treatment in Unresectable Hepatocellular Carcinoma

scientific article published on 27 August 2019

Baseline factors and early viral response (week 4) to antiviral therapy with peginterferon and ribavirin for predicting sustained virologic response in patients infected with hepatitis C virus genotype 1: a multicenter study

scientific article published on January 2013

Branched-chain amino acids as pharmacological nutrients in chronic liver disease

scientific article published on 23 June 2011

Cancer preventive effect of pegylated interferon α-2b plus ribavirin in a real-life clinical setting in Japan: PERFECT interim analysis

scientific article published on 28 June 2011

Case-control study for the identification of virological factors associated with fulminant hepatitis B.

scientific article published on 23 April 2009

Changes in hepatitis C viral load during first 14 days can predict the undetectable time point of serum viral load by pegylated interferon and ribavirin therapy

scientific article published in March 2011

Changes in plasma vascular endothelial growth factor at 8 weeks after sorafenib administration as predictors of survival for advanced hepatocellular carcinoma

scientific article

Changes of HCV quasispecies during combination therapy with interferon and ribavirin

scientific article published in June 2004

Changes of liver stiffness measured by magnetic resonance elastography during direct-acting antivirals treatment in patients with chronic Hepatitis C

scientific article published on 05 September 2020

Characteristics and outcomes of HCV genotype-1-infected patients treated with peginterferon and ribavirin combination therapy with discordant HCV responses 4 and 12 weeks after starting therapy

scientific article published on 28 June 2014

Characterization of naturally occurring protease inhibitor-resistance mutations in genotype 1b hepatitis C virus patients

scientific article published on 18 August 2011

Chronic hepatitis delta virus infection with genotype IIb variant is correlated with progressive liver disease

scientific article published in December 2003

Clinical Utility of Mac-2 Binding Protein Glycosylation Isomer in Chronic Liver Diseases

scientific article published on 01 January 2021

Clinical characteristics of patients who developed hepatocellular carcinoma after hepatitis C virus eradication with interferon therapy: current status in Japan

scientific article published on January 2013

Clinical characteristics of the hepatocellular carcinoma in alcoholic liver disease

scientific article published in January 2015

Clinical effectiveness of bipolar radiofrequency ablation for small liver cancers

scientific article published on 10 October 2012

Clinical features associated with radiological response to sorafenib in unresectable hepatocellular carcinoma: a large multicenter study in Japan

scientific article published on 10 June 2014

Clinical implication of hypovascular hepatocellular carcinoma studied in 4,474 patients with solitary tumour equal or less than 3 cm.

scientific article

Clinical practice guidelines for hepatocellular carcinoma: The Japan Society of Hepatology 2017 (4th JSH-HCC guidelines) 2019 update

scientific article published on 06 September 2019

Clinical validation of an immunochromatographic SARS-Cov-2 IgM/IgG antibody assay with Japanese cohort

scientific article published on 28 July 2020

Combination therapy of interferon plus ribavirin for chronic hepatitis C

scientific article

Comparison of medication adherence and satisfaction between entecavir and tenofovir alafenamide therapy in chronic hepatitis B

scientific article published on 29 January 2020

Comparison of resection and ablation for hepatocellular carcinoma: a cohort study based on a Japanese nationwide survey

scientific article

Comparison of standard-dose and half‑dose sorafenib therapy on clinical outcome in patients with unresectable hepatocellular carcinoma in field practice: A propensity score matching analysis

scientific article published on 16 September 2014

Complex Pattern of Resistance-Associated Substitutions of Hepatitis C Virus after Daclatasvir/Asunaprevir Treatment Failure

scientific article

Core promoter/pre-core mutations are associated with lamivudine-induced HBeAg loss in chronic hepatitis B with genotype C.

scientific article

Correction: Elastin Fiber Accumulation in Liver Correlates with the Development of Hepatocellular Carcinoma

scientific article published on 15 August 2016

Corrigendum to: “Comparison of resection and ablation for hepatocellular carcinoma: A cohort study based on a Japanese nationwide survey” [J Hepatol 2013;58:724–729]

scholarly article published in Journal of Hepatology

Cost-effectiveness analysis of lenvatinib treatment for patients with unresectable hepatocellular carcinoma (uHCC) compared with sorafenib in Japan.

scientific article published on 20 February 2019

Current Status of Hepatocellular Carcinoma Treatment in Japan

Daclatasvir combined with peginterferon alfa-2a and ribavirin in Japanese patients infected with hepatitis C genotype 1.

scientific article published on 22 January 2014

Daclatasvir plus asunaprevir for chronic HCV genotype 1b infection

scientific article

Data mining model using simple and readily available factors could identify patients at high risk for hepatocellular carcinoma in chronic hepatitis C.

scientific article

Demonstration of quality of care measurement using the Japanese liver cancer registry

scientific article

Detectable HBV DNA during nucleos(t)ide analogues stratifies predictive hepatocellular carcinoma risk score

scientific article published on 03 August 2020

Development of hepatocellular carcinoma after interferon therapy in chronic hepatitis C. Is it possible to reduce the incidence by ribanirin and IFN combination therapy?

scientific article published in January 2005

Diagnosis and treatment under laparoscopy for chronic hepatitis C and hepatocellular carcinoma

scientific article published in October 2008

Diagnosis of Fibrosis and Activity by a Combined Use of Strain and Shear Wave Imaging in Patients with Liver Disease

scientific article published on 17 October 2017

Diagnostic and treatment algorithm of the Japanese society of hepatology: a consensus-based practice guideline

scientific article published on 8 July 2010

Discrimination of fibrotic staging of chronic hepatitis C using multiple fibrotic markers

scientific article published on 18 September 2013

Distribution of hepatitis B virus genotypes among patients with chronic infection in Japan shifting toward an increase of genotype A.

scientific article published on 18 March 2009

Does interferon-free direct-acting antiviral therapy for hepatitis C after curative treatment for hepatocellular carcinoma lead to unexpected recurrences of HCC? A multicenter study by the Japanese Red Cross Hospital Liver Study Group.

scientific article published on 16 April 2018

Early decrease in α-fetoprotein, but not des-γ-carboxy prothrombin, predicts sorafenib efficacy in patients with advanced hepatocellular carcinoma

scientific article published on 23 November 2011

Early hepatocellular carcinoma as a signaling lesion for subsequent malignancy

scientific article published on 12 September 2016

Early radiological response evaluation with response evaluation criteria in solid tumors 1.1 stratifies survival in hepatocellular carcinoma patients treated with lenvatinib

scientific article published on 16 October 2020

Effect of aging on risk for hepatocellular carcinoma in chronic hepatitis C virus infection ⬇️

scientific article published on August 1, 2010

Effect of surgical margin width after R0 resection for intrahepatic cholangiocarcinoma: A nationwide survey of the Liver Cancer Study Group of Japan

scientific article published on 07 February 2020

Effect of vitamin K2 on the recurrence of hepatocellular carcinoma

Effects of Subsequent Systemic Anticancer Medication Following First-Line Lenvatinib: A Post Hoc Responder Analysis from the Phase 3 REFLECT Study in Unresectable Hepatocellular Carcinoma

scientific article published on 16 December 2019

Effects of antiviral therapy for hepatitis C following treatment of hepatocellular carcinoma: survey findings of the Japanese Red Cross Liver Study Group

scientific article

Efficacy and resistance of entecavir following 3 years of treatment of Japanese patients with lamivudine-refractory chronic hepatitis B.

scientific article

Efficacy and safety of glecaprevir/pibrentasvir as retreatment therapy for patients with genotype 2 chronic hepatitis C who failed prior sofosbuvir plus ribavirin regimen

scientific article published on 10 July 2019

Efficacy of daclatasvir plus asunaprevir in patients with hepatitis C virus infection undergoing and not undergoing hemodialysis.

scientific article

Efficacy of hepatitis C virus eradication after curative treatment for hepatocellular carcinoma in patients with advanced hepatocellular carcinoma and decreased hepatic functional reserve: A nationwide, multicentre study by the Japanese Red Cross Li

scientific article published in 2022

Efficacy of sorafenib, molecular targeting drug, for advanced hepatocellular carcinoma

scientific article published on October 1, 2010

Elastin Fiber Accumulation in Liver Correlates with the Development of Hepatocellular Carcinoma

scientific article

Enhancement of mitochondrial gene expression in the liver of primary biliary cirrhosis

scientific article published in January 2005

Epithelioid hemangioendothelioma of the liver diagnosed by laparoscopy guided biopsy

scientific article published in November 2008

Erratum to: Efficacy and resistance of entecavir following 3 years of treatment of Japanese patients with lamivudine-refractory chronic hepatitis B.

scientific article published on 30 October 2010

Evidence-based Clinical Practice Guidelines for Hepatocellular Carcinoma: The Japan Society of Hepatology 2013 update (3rd JSH-HCC Guidelines).

scientific article published in January 2015

Expression of keratin 19 is related to high recurrence of hepatocellular carcinoma after radiofrequency ablation

scientific article published on 7 July 2011

External validation of FIB-4: diagnostic accuracy is limited in elderly populations

scientific article published on 01 January 2008

FGF3/FGF4 amplification and multiple lung metastases in responders to sorafenib in hepatocellular carcinoma

scientific article published on 11 February 2013

Factors predictive of sustained virological response following 72 weeks of combination therapy for genotype 1b hepatitis C.

scientific article published on 19 January 2011

Features of resistance-associated substitutions after failure of multiple direct-acting antiviral regimens for hepatitis C

scientific article published on 18 June 2020

Fibrosis score consisting of four serum markers successfully predicts pathological fibrotic stages of chronic hepatitis B

scientific article published on 07 November 2012

Genetic Polymorphisms of IL28B and PNPLA3 Are Predictive for HCV Related Rapid Fibrosis Progression and Identify Patients Who Require Urgent Antiviral Treatment with New Regimens

scientific article published on 9 September 2015

Genetic variation near interleukin 28B and the risk of hepatocellular carcinoma in patients with chronic hepatitis C.

scientific article published on 17 July 2013

Genome-Wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection

scientific article

Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean

scientific article

Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C

scientific journal article

Genome-wide association study identified new susceptible genetic variants in HLA class I region for hepatitis B virus-related hepatocellular carcinoma.

scientific article

Genome-wide association study identifies a PSMD3 variant associated with neutropenia in interferon-based therapy for chronic hepatitis C

scientific article

Guidelines for the antiviral therapy of hepatitis C virus carriers with normal serum aminotransferase based on platelet counts

scientific article published in January 2008

Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis B virus infection for the fiscal year 2008 in Japan

scientific article published in January 2010

Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis C virus infection for the fiscal year 2008 in Japan

scientific article published in January 2010

Hepatic Arterial Infusion Chemotherapy versus Sorafenib in Patients with Advanced Hepatocellular Carcinoma

scientific article published on 24 July 2020

Hepatic IFNL4 expression is associated with non-response to interferon-based therapy through the regulation of basal interferon-stimulated gene expression in chronic hepatitis C patients

scientific article

Hepatic steatosis in chronic hepatitis C is a significant risk factor for developing hepatocellular carcinoma independent of age, sex, obesity, fibrosis stage and response to interferon therapy ⬇️

scientific article published on September 1, 2010

Hepatitis B surface antigen reduction as a result of switching from long-term entecavir administration to tenofovir

scientific article published on 24 October 2019

Hepatitis B viral mutation and its clinical significance

scientific article published in August 2004

Hepatitis C Virus Nonstructural Protein 5A Inhibits Tumor Necrosis Factor–α–Mediated Apoptosis in Huh7 Cells ⬇️

scientific article published on November 11, 2003

Hepatocellular Carcinoma Risk Assessment for Patients With Advanced Fibrosis After Eradication of Hepatitis C Virus

scientific article published in 2021

Hepatocellular carcinoma risk assessment using gadoxetic acid-enhanced hepatocyte phase magnetic resonance imaging.

scientific article published on 24 April 2014

High-sensitivity C-reactive protein (hs-CRP): a promising biomarker for the screening of non-alcoholic steatohepatitis (NASH)

scientific article published in June 2006

How to use viral genomic analysis in clinical practice: chronic hepatitis B and C

scientific article published in April 2006

Hyperglycemia is a significant prognostic factor of hepatocellular carcinoma after curative therapy

scientific article published on January 2013

Identifying candidates with favorable prognosis following liver transplantation for hepatocellular carcinoma: Data mining analysis

scientific article

Imaging diagnosis and molecular profiling of hepatocellular carcinoma

scientific article published on January 2016

Impact of Advanced Age on Survival in Patients Undergoing Resection of Hepatocellular Carcinoma: Report of a Japanese Nationwide Survey

scientific article

Impact of histologically confirmed lymph node metastases on patient survival after surgical resection for hepatocellular carcinoma: report of a Japanese nationwide survey

scientific article published in January 2014

Impact of pre-sarcopenia in sorafenib treatment for advanced hepatocellular carcinoma.

scientific article published on 18 June 2018

Impact of resection and ablation for single hypovascular hepatocellular carcinoma ≤2 cm analysed with propensity score weighting

scientific article published on 21 December 2017

Impact of resistance-associated variant dominancy on treatment in patients with HCV genotype 1b receiving daclatasvir/asunaprevir.

scientific article

Impaired brain activity in cirrhotic patients with minimal hepatic encephalopathy: Evaluation by near-infrared spectroscopy

scientific article published on 15 May 2013

Impaired brain function improved by L-carnitine in patients with cirrhosis: evaluation using near-infrared spectroscopy

scientific article published on 11 August 2020

Incidence and clinical course of major depression in patients with chronic hepatitis type C undergoing interferon-alpha therapy: a prospective study

scientific article published on 01 January 2003

Influence of hepatitis B virus X and core promoter mutations on hepatocellular carcinoma among patients infected with subgenotype C2.

scientific article

Influence of hepatitis B virus genotypes on the intra- and extracellular expression of viral DNA and antigens.

scientific article published on October 2006

Inhibition of hepatocellular carcinoma by PegIFNα-2a in patients with chronic hepatitis C: a nationwide multicenter cooperative study

scientific article published on 9 August 2012

Interferon-stimulated gene expression and hepatitis C viral dynamics during different interferon regimens

scientific article published on September 2003

Interleukin 28B polymorphism predicts interferon plus ribavirin treatment outcome in patients with hepatitis C virus-related liver cirrhosis: A multicenter retrospective study in Japan

scientific article published on 9 January 2014

Investigation of Anti-SARS-CoV-2 IgG and IgM Antibodies in the Patients with COVID-19 by Three Different ELISA Test Kits

scientific article published on 23 July 2020

Irregular vascular pattern by contrast-enhanced ultrasonography and high serum Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein level predict poor outcome after successful radiofrequency ablation in patients with early-stage hepatoce

scientific article published on 17 October 2016

Is platelet monitoring during 7-day lusutrombopag treatment necessary in chronic liver disease patients with thrombocytopenia undergoing planned invasive procedures? A phase 3b open-label study

scientific article published on 01 July 2020

Is the incidence of intrahepatic multicentric recurrence of hepatocellular carcinoma more frequent in "the carcinogenic stage" than in liver cirrhosis?

scientific article

Issues in need for a solution among patients with successful eradication of hepatitis C virus

scientific article published on January 2016

JSH Consensus Kobe 2009: Diagnosis and Treatment of Hepatitis B

JSH Consensus Kobe 2009: Diagnosis and Treatment of Hepatitis C

JSH Consensus-Based Clinical Practice Guidelines for the Management of Hepatocellular Carcinoma: 2014 Update by the Liver Cancer Study Group of Japan

scientific article (publication date: October 2014)

JSH Guidelines for the Management of Hepatitis C Virus Infection: 2019 Update Protective effect of antiviral therapy against hepatocarcinogenesis

scientific article published on 16 April 2020

JSH Guidelines for the Management of Hepatitis C Virus Infection: A 2016 update for genotype 1 and 2.

scientific article

L-carnitine Reduces Muscle Cramps in Patients With Cirrhosis

scientific article published on 9 December 2014

Laparoscopic radiofrequency ablation for hepatocellular carcinoma

scientific article published on April 2009

Large-scale viral genome analysis identifies novel clinical associations between hepatitis B virus and chronically infected patients

scientific article published on 19 July 2019

LecT-Hepa, a glyco-marker derived from multiple lectins, as a predictor of liver fibrosis in chronic hepatitis C patients.

scientific article published on October 2012

Ledipasvir and sofosbuvir fixed-dose combination with and without ribavirin for 12 weeks in treatment-naive and previously treated Japanese patients with genotype 1 hepatitis C: an open-label, randomised, phase 3 trial

scientific article published on 8 April 2015

Lenvatinib as an Initial Treatment in Patients with Intermediate-Stage Hepatocellular Carcinoma Beyond Up-To-Seven Criteria and Child-Pugh A Liver Function: A Proof-Of-Concept Study

scientific article published on 31 July 2019

Liver Cancer Working Group report.

scientific article published on September 2010

Liver Resection for Multiple Hepatocellular Carcinomas: A Japanese Nationwide Survey

scientific article published on 16 January 2019

Liver injury with COVID-19 based on gastrointestinal symptoms and pneumonia severity

scientific article published on 04 November 2020

Liver resection for hepatocellular carcinoma associated with hepatic vein invasion: A Japanese nationwide survey

scientific article published on 24 April 2017

Long time oral supplementation with branched-chain amino acids improves survival and decreases recurrences in patients with hepatocellular carcinoma

scientific article published in June 2008

Lusutrombopag Is Safe and Efficacious for Treatment of Thrombocytopenia in Patients With and Without Hepatocellular Carcinoma

scientific article published on 20 March 2020

Lusutrombopag Reduces Need for Platelet Transfusion in Patients With Thrombocytopenia Undergoing Invasive Procedures

scientific article published on 28 November 2018

Management of ascites in cirrhotic patients

scientific article published on January 2017

Management of hepatitis B: Consensus of the Japan Society of Hepatology 2009.

scientific article published on 11 November 2010

Management of hepatocellular carcinoma in Japan: Consensus-Based Clinical Practice Guidelines proposed by the Japan Society of Hepatology (JSH) 2010 updated version.

scientific article published on 9 August 2011

Model incorporating the ITPA genotype identifies patients at high risk of anemia and treatment failure with pegylated-interferon plus ribavirin therapy for chronic hepatitis C.

scientific article published on 7 January 2013

Multicenter study of pegylated interferon α-2a monotherapy for hepatitis C virus-infected patients on hemodialysis: REACH study

scientific article published on 4 September 2014

Mutagenic effects of ribavirin and response to interferon/ribavirin combination therapy in chronic hepatitis C.

scientific article published in October 2005

Mutations in the NS5B region of the hepatitis C virus genome correlate with clinical outcomes of interferon-alpha plus ribavirin combination therapy

scientific article published in September 2005

Nationwide study of 4741 patients with non-B non-C hepatocellular carcinoma with special reference to the therapeutic impact

scientific article

Naturally occurring, resistance-associated hepatitis C virus NS5A variants are linked to interleukin-28B genotype and are sensitive to interferon-based therapy

scientific article published on 6 January 2015

New diagnostic technique to evaluate hepatic steatosis using the attenuation coefficient on ultrasound B mode

scientific article published on 27 August 2019

New susceptibility and resistance HLA-DP alleles to HBV-related diseases identified by a trans-ethnic association study in Asia

scientific article

No Resistance to Tenofovir Alafenamide Detected through 96 Weeks of Treatment in Patients with Chronic Hepatitis B Infection

scientific article published on 24 September 2018

No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations.

scientific article

No increased risk of hepatocellular carcinoma after eradication of hepatitis C virus by direct-acting antivirals, compared with interferon-based therapy

scientific article published in 2022

Non-alcoholic fatty liver disease fibrosis score and FIB-4 scoring system could identify patients at risk of systemic complications

scientific article published on 15 October 2014

Non-invasive liver fibrosis assessment correlates with collagen and elastic fiber quantity in patients with hepatitis C virus infection

scientific article published on 26 December 2018

Non-invasive prediction of hepatocellular carcinoma development using serum fibrosis marker in chronic hepatitis C patients

scientific article published on 15 December 2013

Novel Pretreatment Scoring Incorporating C-reactive Protein to Predict Overall Survival in Advanced Hepatocellular Carcinoma with Sorafenib Treatment

scientific article published on 14 September 2016

Novel quantitative assessment system of liver steatosis using a newly developed attenuation measurement method

scientific article published on 18 May 2018

Objective Response by mRECIST Is an Independent Prognostic Factor for Overall Survival in Hepatocellular Carcinoma Treated with Sorafenib in the SILIUS Trial

scientific article published on 08 October 2019

Once-daily simeprevir with peginterferon and ribavirin for treatment-experienced HCV genotype 1-infected patients in Japan: the CONCERTO-2 and CONCERTO-3 studies

scientific article published on 14 March 2014

Optimal timing of interferon treatment for acute hepatitis C.

scientific article published on 21 November 2005

Orantinib versus placebo combined with transcatheter arterial chemoembolisation in patients with unresectable hepatocellular carcinoma (ORIENTAL): a randomised, double-blind, placebo-controlled, multicentre, phase 3 study

scientific article published on 4 October 2017

Panel discussion: Management of hepatocellular carcinoma

Pegylated interferon-associated retinopathy in chronic hepatitis C patients

scientific article published on 01 May 2006

Peretinoin after curative therapy of hepatitis C-related hepatocellular carcinoma: a randomized double-blind placebo-controlled study

scientific article

Pharmacokinetics of ribavirin in combined interferon-alpha 2b and ribavirin therapy for chronic hepatitis C virus infection

scientific article published in April 2003

Polymerase domain B mutation is associated with hepatitis relapse during long-term lamivudine therapy for chronic hepatitis B.

scientific article published in November 2005

Potential relevance of cytoplasmic viral sensors and related regulators involving innate immunity in antiviral response

scientific article published on 14 February 2008

Pre-treatment prediction of response to pegylated-interferon plus ribavirin for chronic hepatitis C using genetic polymorphism in IL28B and viral factors

scientific article published on 19 September 2010

Prediction and prevention of intrahepatic recurrence of hepatocellular carcinoma

scientific article published on 19 December 2011

Prediction of Hepatocellular Carcinoma After Sustained Virological Responses Using Magnetic Resonance Elastography

scientific article published on 28 November 2018

Prediction of Prognosis of Intermediate-Stage HCC Patients: Validation of the Tumor Marker Score in a Nationwide Database in Japan

scientific article published on 18 February 2019

Prediction of diuretic response to tolvaptan by a simple, readily available spot urine Na/K ratio

scientific article

Prediction of response to peg-interferon plus ribavirin therapy for chronic hepatitis C

scientific article published in July 2011

Prediction of response to peginterferon and ribavirin therapy for chronic hepatitis C analyzed by data mining method

scientific article

Predictive values of amino acid sequences of the core and NS5A regions in antiviral therapy for hepatitis C: a Japanese multi-center study

scientific article published on 11 June 2009

Predictors of virological response to a combination therapy with pegylated interferon plus ribavirin including virus and host factors ⬇️

scientific article published on 5 September 2010

Present status of the treatment of chronic hepatitis C in Japan compared from Western countries

scientific article published in June 2004

Pretreatment Gastric Lavage Reduces Postoperative Bleeding after Endoscopic Submucosal Dissection for Gastric Neoplasms

scientific article published on 12 February 2016

Pretreatment prediction of anemia progression by pegylated interferon alpha-2b plus ribavirin combination therapy in chronic hepatitis C infection: decision-tree analysis

scientific article published on 17 June 2011

Pretreatment prediction of response to peginterferon plus ribavirin therapy in genotype 1 chronic hepatitis C using data mining analysis ⬇️

scientific article published on September 10, 2010

Pretreatment prediction of the outcome of response-guided peginterferon-α and ribavirin therapy for chronic hepatitis C.

scientific article

Prevention of adverse effects in ribavirin and interferon combination therapy

scientific article published in July 2004

Prognostic impact of spontaneous tumor rupture in patients with hepatocellular carcinoma: an analysis of 1160 cases from a nationwide survey

scientific article published in March 2014

Prolonged treatment with pegylated interferon alpha 2b plus ribavirin improves sustained virological response in chronic hepatitis C genotype 1 patients with late response in a clinical real-life setting in Japan

scientific article published on 25 September 2009

Proposal of Japan Red Cross score for sorafenib therapy in hepatocellular carcinoma

scientific article published on 11 January 2015

Proposal of a new staging system for intrahepatic cholangiocarcinoma: Analysis of surgical patients from a nationwide survey of the Liver Cancer Study Group of Japan.

scientific article

Prospective comparison of real-time tissue elastography and serum fibrosis markers for the estimation of liver fibrosis in chronic hepatitis C patients

scientific article published on 10 July 2013

Prospective randomized crossover trial of combination therapy with bezafibrate and UDCA for primary biliary cirrhosis

scientific article published in August 2004

Quantification of collagen and elastic fibers using whole-slide images of liver biopsy specimens.

scientific article published in June 2013

REFLECT-a phase 3 trial comparing efficacy and safety of lenvatinib to sorafenib for the treatment of unresectable hepatocellular carcinoma: an analysis of Japanese subset

scientific article published on 12 November 2019

Randomised, multicentre prospective trial of transarterial chemoembolisation (TACE) plus sorafenib as compared with TACE alone in patients with hepatocellular carcinoma: TACTICS trial

scientific article published on 04 December 2019

Real-life experience of lusutrombopag for cirrhotic patients with low platelet counts being prepared for invasive procedures

scientific article published on 15 February 2019

Real-world efficacy and safety of ledipasvir and sofosbuvir in patients with hepatitis C virus genotype 1 infection: a nationwide multicenter study by the Japanese Red Cross Liver Study Group.

scientific article

Real-world efficacy and safety of sofosbuvir + ribavirin for hepatitis C genotype 2: A nationwide multicenter study by the Japanese Red Cross Liver Study Group

scientific article published on 20 October 2018

Real-world efficacy of elbasvir and grazoprevir for hepatitis C virus (genotype 1): A nationwide, multicenter study by the Japanese Red Cross Hospital Liver Study Group ⬇️

scientific article published on 14 June 2019

Recent advances of radiofrequency ablation for early hepatocellular carcinoma

scientific article published on January 2011

Reduced organic anion transporter expression is a risk factor for hepatocellular carcinoma in chronic hepatitis C patients: a propensity score matching study

scientific article published on 8 January 2014

Relationship between polymorphisms of the inosine triphosphatase gene and anaemia or outcome after treatment with pegylated interferon and ribavirin

scientific article published in January 2011

Relative dose intensity over the first four weeks of lenvatinib therapy is a factor of favorable response and overall survival in patients with unresectable hepatocellular carcinoma

scientific article published on 20 April 2020

Repeated radiofrequency ablation for the distant recurrence in the liver in patients with chronic hepatitis C virus infection achieving long-term survival

scientific article published in September 2007

Reply

scientific article published on 30 January 2019

Reply: To PMID 23564522

scientific article published on 18 June 2014

Reply: To PMID 24734314.

scientific article published in September 2014

Report of the 19th follow-up survey of primary liver cancer in Japan

scientific article

Report of the 20th Nationwide follow-up survey of primary liver cancer in Japan

scientific article published on 05 January 2020

Report of the 21st Nationwide Follow-Up Survey of Primary Liver Cancer in Japan (2010-2011)

scientific article published on 31 December 2020

Reproducibility and usability of chronic virus infection model using agent-based simulation; comparing with a mathematical model

scientific article published on 12 September 2009

Resistance-Associated NS5A Variants of Hepatitis C Virus Are Susceptible to Interferon-Based Therapy

scientific article published on 14 September 2015

Response criteria of tolvaptan for the treatment of hepatic edema

scientific article

Retreatment with peginterferon α-2a + ribavirin in patients who failed previous peginterferon α-2b + ribavirin combination therapy

scientific article published on 13 December 2012

Risk assessment of hepatocellular carcinoma development by magnetic resonance elastography in chronic hepatitis C patients who achieved sustained virological responses by direct-acting antivirals

scientific article published on 03 May 2019

Risk factors for exceeding the Milan criteria after successful radiofrequency ablation in patients with early-stage hepatocellular carcinoma

scientific article published on March 2014

Risk of hepatocellular carcinoma in cirrhotic hepatitis B virus patients during nucleoside/nucleotide analog therapy

scientific article published on 22 September 2014

Role of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging in the management of hepatocellular carcinoma: consensus at the Symposium of the 48th Annual Meeting of the Liver Cancer Study Group of Japan

scientific article published on 20 February 2013

Safety and efficacy of elbasvir and grazoprevir in Japanese hemodialysis patients with genotype 1b hepatitis C virus infection

scientific article published on 17 July 2018

Safety and efficacy of glecaprevir and pibrentasvir in Japanese hemodialysis patients with genotype 2 hepatitis C virus infection

scientific article published on 18 February 2019

Safety and efficacy of sorafenib in Japanese patients with hepatocellular carcinoma in clinical practice: a subgroup analysis of GIDEON.

scientific article published on 22 April 2016

Safety and efficacy of tigatuzumab plus sorafenib as first-line therapy in subjects with advanced hepatocellular carcinoma: A phase 2 randomized study

scientific article published on 10 June 2015

Sequence elements correlating with circulating viral load in genotype 1b hepatitis C virus infection

scientific article published on July 2003

Sequences in the interferon sensitivity-determining region and core region of hepatitis C virus impact pretreatment prediction of response to PEG-interferon plus ribavirin: data mining analysis

scientific article

Serum HBV RNA as a possible marker of HBV replication in the liver during nucleot(s)ide analogue therapy

scientific article

Serum KL-6 as a novel tumor marker for hepatocellular carcinoma in hepatitis C virus infected patients

scientific article

Serum Wisteria Floribunda Agglutinin-Positive Sialylated Mucin 1 as a Marker of Progenitor/Biliary Features in Hepatocellular Carcinoma

scientific article

Significance of a reduction in HCV RNA levels at 4 and 12 weeks in patients infected with HCV genotype 1b for the prediction of the outcome of combination therapy with peginterferon and ribavirin

scientific article

Simeprevir (TMC435) once daily with peginterferon-α-2b and ribavirin in patients with genotype 1 hepatitis C virus infection: The CONCERTO-4 study

scientific article published on 29 July 2014

Simeprevir with peginterferon/ribavirin for treatment-naïve hepatitis C genotype 1 patients in Japan: CONCERTO-1, a phase III trial

scientific article published on 12 April 2014

Sofosbuvir plus ribavirin in Japanese patients with chronic genotype 2 HCV infection: an open-label, phase 3 trial

scientific article published on 8 September 2014

Sofosbuvir-velpatasvir plus ribavirin in Japanese patients with genotype 1 or 2 hepatitis C who failed direct-acting antivirals

scientific article published on 20 July 2018

Sorafenib Therapy for BCLC Stage B/C Hepatocellular Carcinoma; Clinical Outcome and Safety in Aged Patients: A Multicenter Study in Japan

scientific article

Sorafenib plus low-dose cisplatin and fluorouracil hepatic arterial infusion chemotherapy versus sorafenib alone in patients with advanced hepatocellular carcinoma (SILIUS): a randomised, open label, phase 3 trial

scientific article published on 07 April 2018

Sorafenib-Regorafenib Sequential Therapy in Japanese Patients with Unresectable Hepatocellular Carcinoma-Relative Dose Intensity and Post-Regorafenib Therapies in Real World Practice

scientific article published on 09 October 2019

Spatial and chronological differences in hepatitis B virus genotypes from patients with acute hepatitis B in Japan

scientific article published on 7 September 2006

Specific mutations in enhancer II/core promoter of hepatitis B virus subgenotypes C1/C2 increase the risk of hepatocellular carcinoma.

scientific article published on 10 August 2006

Strategy for advanced hepatocellular carcinoma based on liver function and portal vein tumor thrombosis

scientific article published on 13 September 2020

Subgroup analysis of efficacy and safety of orantinib in combination with TACE in Japanese HCC patients in a randomized phase III trial (ORIENTAL)

scientific article published on 03 May 2019

Superselective transarterial chemoembolization for hepatocellular carcinoma. Validation of treatment algorithm proposed by Japanese guidelines

scientific article published on 13 December 2011

Surveillance and diagnostic algorithm for hepatocellular carcinoma proposed by the Liver Cancer Study Group of Japan: 2014 update

scientific article

Survey of survival among patients with hepatitis C virus-related hepatocellular carcinoma treated with peretinoin, an acyclic retinoid, after the completion of a randomized, placebo-controlled trial

scientific article published on 11 September 2014

Survival Analysis over 28 Years of 173,378 Patients with Hepatocellular Carcinoma in Japan

scientific article published on 10 May 2016

Survival Benefit of Locoregional Treatment for Hepatocellular Carcinoma with Advanced Liver Cirrhosis

scientific article published on 3 May 2016

Survival benefit of liver resection for hepatocellular carcinoma associated with portal vein invasion

scientific article

T1653 mutation in the box alpha increases the risk of hepatocellular carcinoma in patients with chronic hepatitis B virus genotype C infection

scientific article

Targeted DNA and RNA sequencing of fine-needle biopsy FFPE specimens in patients with unresectable hepatocellular carcinoma treated with sorafenib

scientific article

Tenofovir alafenamide for hepatitis B virus infection including switching therapy from tenofovir disoproxil fumarate

scientific article published on 21 May 2019

Tenofovir alafenamide versus tenofovir disoproxil fumarate for the treatment of patients with HBeAg-negative chronic hepatitis B virus infection: a randomised, double-blind, phase 3, non-inferiority trial.

scientific article published on 22 September 2016

The evolutionary patterns of hepatitis C virus subtype 2a and 6a isolates linked to an outbreak in China in 2012

scientific article published on 4 September 2015

The interferon sensitivity determining region in the era of combination therapies and the rational use of such therapies for patients with HCV genotype 1b infection ⬇️

scientific article published on October 1, 2003

The presence of steatosis and elevation of alanine aminotransferase levels are associated with fibrosis progression in chronic hepatitis C with non-response to interferon therapy

scientific article published on 26 February 2008

The prognosis of hepatitis B inactive carriers in Japan: a multicenter prospective study

scientific article published on 15 June 2016

Three criteria for radiological response on survival in patients with hepatocellular carcinoma treated with lenvatinib

scientific article published on 06 September 2019

Tolvaptan for the Treatment of Refractory Ascites

scientific article published on 15 October 2016

Transarterial chemoembolization failure/refractoriness: JSH-LCSGJ criteria 2014 update

scientific article

Treatment Optimization for Hepatocellular Carcinoma in Elderly Patients in a Japanese Nationwide Cohort.

scientific article published on 30 March 2018

Triple therapy with direct acting antiviral agent, peginterferon and ribavirin for chronic hepatitis C

scientific article published in December 2012

Ulcerative colitis developed after acute exacerbation of chronic hepatitis B

scientific article published in July 2002

Understanding of HLA-conferred susceptibility to chronic hepatitis B infection requires HLA genotyping-based association analysis

scientific article published on 19 April 2016

Up-to-seven criteria as a useful predictor for tumor downstaging to within Milan criteria and Child-Pugh grade deterioration after initial conventional transarterial chemoembolization

scientific article published on 26 December 2017

Update strategy for the treatment of chronic hepatitis C.

scientific article published in September 2014

Urinary excretion of the water channel aquaporin 2 correlated with the pharmacological effect of tolvaptan in cirrhotic patients with ascites

scientific article published on 26 November 2015

Use of simeprevir following pre-emptive pegylated interferon/ribavirin treatment for recurrent hepatitis C in living donor liver transplant recipients: a 12-week pilot study

scientific article

Use of the Serum Wisteria floribunda Agglutinin-Positive Mac2 Binding Protein as a Marker of Gastroesophageal Varices and Liver-Related Events in Chronic Hepatitis C Patients

scientific article published on 22 March 2020

Usefulness of neutrophil‐to‐lymphocyte ratio in predicting progression and survival outcomes after atezolizumab–bevacizumab treatment for hepatocellular carcinoma

scientific article published in 2022

Validation and Potential of Albumin-Bilirubin Grade and Prognostication in a Nationwide Survey of 46,681 Hepatocellular Carcinoma Patients in Japan: The Need for a More Detailed Evaluation of Hepatic Function

scientific article published on 22 September 2017

Validation of albumin, bilirubin, and platelet criteria for avoiding screening endoscopy in patients with advanced fibrosis

scientific article published on 09 June 2020

Validation of hepatocellular carcinoma risk scores in Japanese chronic hepatitis B cohort receiving nucleot(s)ide analog

scientific article published on 23 January 2020

Validation of serological models for staging and prognostication of HCC in patients from a Japanese nationwide survey

scientific article published on 21 February 2017

Validation of three staging systems for hepatocellular carcinoma (JIS score, biomarker-combined JIS score and BCLC system) in 4,649 cases from a Japanese nationwide survey

scientific article published on 29 October 2014

Value of highly sensitive fucosylated fraction of alpha-fetoprotein for prediction of hepatocellular carcinoma recurrence after curative treatment

scientific article published on 18 April 2013

Vaniprevir plus peginterferon alfa-2a and ribavirin in treatment-experienced Japanese patients with hepatitis C virus genotype 1 infection: a randomized phase II study

scientific article

Virological escape in HCV genotype-1-infected patients receiving daclatasvir plus ribavirin and peginterferon alfa-2a or alfa-2b

scientific article published on 22 January 2014

Whole Slide Image Analysis System for Quantification of Liver Fibrosis

Wisteria floribunda Agglutinin-Positive Mac-2 Binding Protein as a Screening Tool for Significant Liver Fibrosis in Health Checkup

scientific article published on 22 December 2020

Wisteria floribunda Agglutinin-Positive Mac-2 Binding Protein but not α-fetoprotein as a Long-Term Hepatocellular Carcinoma Predictor ⬇️

scientific article published on 21 May 2020

Wisteria floribunda agglutinin positive human Mac-2-binding protein as a predictor of hepatocellular carcinoma development in chronic hepatitis C patients

scientific article

Wisteria floribunda agglutinin-positive Mac-2 binding protein predicts early occurrence of hepatocellular carcinoma after sustained virologic response by direct-acting antivirals for hepatitis C virus

scientific article published on 23 August 2018

Wisteria floribunda agglutinin-positive mac-2 binding protein as an age-independent fibrosis marker in nonalcoholic fatty liver disease

scientific article published on 12 July 2019

[Noninvasive Estimation of Liver Fibrosis and Hepatocellular Carcinoma Development Using WFA(+)-M2BP in Chronic Hepatitis C Patients].

scientific article published in September 2015

[Various clinical conditions after successful eradication of hepatitis C virus]

scientific article published on 01 January 2018

α-fetoprotein levels after interferon therapy and risk of hepatocarcinogenesis in chronic hepatitis C.

scientific article

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