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List of works by Jan Melenhorst

A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma.

scientific article published in July 2017

Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma

scientific article published on 21 February 2019

Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma.

scientific article published on 19 April 2018

B cell maturation antigen-specific CAR T cells are clinically active in multiple myeloma

scientific article published on 21 March 2019

CD19-targeting CAR T cell immunotherapy outcomes correlate with genomic modification by vector integration

scientific article published on 01 February 2020

CMV-specific T cells generated from naïve T cells recognize atypical epitopes and may be protective in vivo

scientific article published on April 2015

CRISPR-engineered T cells in patients with refractory cancer

scientific article published on 07 February 2020

Cellular kinetics of CTL019 in relapsed/refractory B-cell acute lymphoblastic leukemia and chronic lymphocytic leukemia

scientific article

Chimeric Antigen Receptor T Cells against CD19 for Multiple Myeloma

scientific article

Chimeric antigen receptor T cells for sustained remissions in leukemia

scientific article (publication date: 16 October 2014)

Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia

scientific article published on September 2015

Cytokine Release Syndrome After Chimeric Antigen Receptor T Cell Therapy for Acute Lymphoblastic Leukemia.

scientific article

Cytokine release syndrome associated with chimeric-antigen receptor T-cell therapy: clinicopathological insights

scientific article published on 26 October 2017

Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia

scientific article published on 30 April 2018

Evaluating the skin in patients undergoing chimeric antigen receptor modified T-cell therapy

scientific article published in November 2016

Graft versus leukemia response without graft-versus-host disease elicited by adoptively transferred multivirus-specific T-cells

scientific article published on 30 September 2014

Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia

scientific article published on 26 January 2016

Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia

scientific article

Long-Term Outcomes From a Randomized Dose Optimization Study of Chimeric Antigen Receptor Modified T Cells in Relapsed Chronic Lymphocytic Leukemia

scientific article published on 16 April 2020

Measuring IL-6 and sIL-6R in serum from patients treated with tocilizumab and/or siltuximab following CAR T cell therapy

scientific article published on 2 April 2016

Neurotoxicity after CTL019 in a pediatric and young adult cohort

scientific article published on 26 September 2018

Next-generation CAR T cells to overcome current drawbacks

scientific article published on 27 June 2020

Reducing Ex Vivo Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells

scientific article published on 20 July 2018

Single-cell antigen-specific landscape of CAR T infusion product identifies determinants of CD19-positive relapse in patients with ALL

scientific article published on 08 June 2022

T-cell phenotypes associated with effective CAR T-cell therapy in postinduction vs relapsed multiple myeloma

scientific article published on 01 October 2019

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