List of works - Shumei Song

A Novel YAP1 Inhibitor targets CSCs-enriched Radiation Resistant Cells and Exerts Strong Antitumor Activity in Esophageal Adenocarcinoma.

scientific article published on 22 November 2017

A Phase II Trial of Cytoreduction, Gastrectomy, and Hyperthermic Intraperitoneal Perfusion with Chemotherapy for Patients with Gastric Cancer and Carcinomatosis or Positive Cytology

scientific article published on 17 June 2020

A validated miRNA profile predicts response to therapy in esophageal adenocarcinoma.

scientific article

ABT-263 induces apoptosis and synergizes with chemotherapy by targeting stemness pathways in esophageal cancer

scientific article

ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade

scientific article published on 07 May 2018

An improved strategy for CRISPR/Cas9 gene knockout and subsequent wildtype and mutant gene rescue

scientific article published on 13 February 2020

Anti-angiogenic agent ramucirumab: meaningful or marginal?

scientific article published on 07 March 2014

Attenuation of YAP1 can potentially target cancer stem cells to overcome drug resistance

Bile acids induce MUC2 overexpression in human colon carcinoma cells

scientific article

COX-2 induction by unconjugated bile acids involves reactive oxygen species-mediated signalling pathways in Barrett's oesophagus and oesophageal adenocarcinoma

scientific article published on 29 June 2007

Cancer stem cells in esophageal cancer and response to therapy

scientific article published on 25 October 2018

Cancer stem cells: the promise and the potential.

scientific article published on 21 January 2015

Chk1 inhibition potentiates the therapeutic efficacy of PARP inhibitor BMN673 in gastric cancer

scientific article published on March 2017

Clinical and genomic landscape of gastric cancer with a mesenchymal phenotype.

scientific article published on 3 May 2018

Current status of ramucirumab in gastroesophageal adenocarcinoma.

scientific article

Dysfunctional transforming growth factor-β signaling with constitutively active Notch signaling in Barrett's esophageal adenocarcinoma

scientific article published on 8 February 2011

Exploiting Molecular and Immune Biology of Gastric and Gastroesophageal Adenocarcinomas to Discover Novel Therapeutic Targets.

scientific article

Factors Associated with Resection and Survival After Laparoscopic HIPEC for Peritoneal Gastric Cancer Metastasis

scientific article published on 09 July 2020

Galectin-3 Mediates Tumor Cell-Stroma Interactions by Activating Pancreatic Stellate Cells to Produce Cytokines via Integrin Signaling.

scientific article published on 21 December 2017

Galectin-3 expression is prognostic in diffuse type gastric adenocarcinoma, confers aggressive phenotype, and can be targeted by YAP1/BET inhibitors

scientific article

Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity ⬇️

scientific article

Galectin-3 modulates MUC2 mucin expression in human colon cancer cells at the level of transcription via AP-1 activation

scientific article published on November 2005

Gastric adenocarcinoma.

scientific article published on June 2017

Gastric cancer-molecular and clinical dimensions

scientific article published on 24 September 2013

Genetic alterations and expression characteristics of ARID1A impact tumor immune contexture and survival in early-onset gastric cancer

scientific article published on 01 November 2020

H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer

scientific article

Hippo coactivator YAP1 upregulates SOX9 and endows esophageal cancer cells with stem-like properties

scientific article published on 6 June 2014

Induction of MUC5AC mucin by conjugated bile acids in the esophagus involves the phosphatidylinositol 3-kinase/protein kinase C/activator protein-1 pathway

scientific article

Inhibition of the ATM/Chk2 axis promotes cGAS/STING signaling in ARID1A-deficient tumors

scientific article published on 05 October 2020

Integrated genomic profiling and modelling for risk stratification in patients with advanced oesophagogastric adenocarcinoma

scientific article published on 17 December 2020

Introduction

Is phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway therapeutic target for esophageal adenocarcinoma

scientific article published on 08 November 2017

Large tumor suppressor homologs 1 and 2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZ.

scientific article published on 17 August 2016

Liquid biopsies in gastrointestinal malignancies: when is the big day?

scientific article published on 4 December 2017

LncRNA PVT1 Is a Poor Prognosticator and Can Be Targeted by PVT1 Antisense Oligos in Gastric Adenocarcinoma

scientific article published on 15 October 2020

LncRNA PVT1 up-regulation is a poor prognosticator and serves as a therapeutic target in esophageal adenocarcinoma

scientific article published on 10 October 2019

Loss of TGF-β adaptor β2SP activates notch signaling and SOX9 expression in esophageal adenocarcinoma

scientific article published on 27 March 2013

Medical management of gastric cancer: a 2014 update

scientific article

Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancer

scientific article

Molecular biology and immunology of gastric cancer peritoneal metastasis

scientific article published on 05 October 2020

Molecular biomarkers in gastric cancer.

scientific article published on April 2015

Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response

scientific article published on 06 June 2019

Nuclear expression of Gli-1 is predictive of pathologic complete response to chemoradiation in trimodality treated oesophageal cancer patients.

scientific article published on 20 July 2017

Overexpressed Galectin-3 in Pancreatic Cancer Induces Cell Proliferation and Invasion by Binding Ras and Activating Ras Signaling ⬇️

scientific article published on August 10, 2012

PPARδ Interacts with the Hippo Coactivator YAP1 to Promote SOX9 Expression and Gastric Cancer Progression

scientific article published on 03 December 2019

Phase I Trial of Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) with Cisplatin, Mitomycin, and Paclitaxel in Patients with Gastric Adenocarcinoma and Associated Carcinomatosis or Positive Cytology

scientific article published on 23 January 2020

Polyphenon E inhibits the growth of human Barrett's and aerodigestive adenocarcinoma cells by suppressing cyclin D1 expression

scientific article

Post-trimodality expression levels of metadherin (MTDH) as a prognostic biomarker for esophageal adenocarcinoma patients.

scientific article

Potentially functional variants in the core nucleotide excision repair genes predict survival in Japanese gastric cancer patients

scientific article

Preoperative Therapy for Gastric Adenocarcinoma is Protective for Poor Oncologic Outcomes in Patients with Complications After Gastrectomy

scientific article published on 09 July 2018

Proteomics approach to identify biomarkers for upper gastrointestinal cancer.

scientific article

Reply

scientific article published on 10 August 2018

Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma

scientific article published on 04 January 2021

Targeting Hippo coactivator YAP1 through BET bromodomain inhibition in esophageal adenocarcinoma

scientific article published on 16 March 2020

Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGF-β Signaling

scientific article published on 03 March 2020

The DNA Endonuclease Mus81 Regulates ZEB1 Expression and Serves as a Target of BET4 Inhibitors in Gastric Cancer

scientific article published on 29 May 2019

The Hippo Coactivator YAP1 Mediates EGFR Overexpression and Confers Chemoresistance in Esophageal Cancer

scientific article

The Long Noncoding RNA CCAT2 induces chromosomal instability through BOP1 - AURKB signaling

scientific article published on 14 August 2020

The role of hedgehog signaling in gastric cancer: molecular mechanisms, clinical potential, and perspective

scientific article published on 27 November 2019

Translating genomic profiling to gastrointestinal cancer treatment

scientific article

Tumor-associated macrophage infiltration is highly associated with PD-L1 expression in gastric adenocarcinoma.

scientific article published on 11 August 2017

YAP1 mediates gastric adenocarcinoma peritoneal metastases that are attenuated by YAP1 inhibition

scientific article published on 27 April 2020

YAP1-Mediated CDK6 Activation Confers Radiation Resistance in Esophageal Cancer - Rationale for the Combination of YAP1 and CDK4/6 Inhibitors in Esophageal Cancer

scientific article published on 18 December 2018

Yield of peritoneal cytology in staging patients with gastric and gastroesophageal cancer

scientific article published on 14 October 2019

iTALK: an R Package to Characterize and Illustrate Intercellular Communication

scholarly article published 4 January 2019

List of works by Shumei Song

A Novel YAP1 Inhibitor targets CSCs-enriched Radiation Resistant Cells and Exerts Strong Antitumor Activity in Esophageal Adenocarcinoma.

A Phase II Trial of Cytoreduction, Gastrectomy, and Hyperthermic Intraperitoneal Perfusion with Chemotherapy for Patients with Gastric Cancer and Carcinomatosis or Positive Cytology

A validated miRNA profile predicts response to therapy in esophageal adenocarcinoma.

ABT-263 induces apoptosis and synergizes with chemotherapy by targeting stemness pathways in esophageal cancer

ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade

An improved strategy for CRISPR/Cas9 gene knockout and subsequent wildtype and mutant gene rescue

Anti-angiogenic agent ramucirumab: meaningful or marginal?

Attenuation of YAP1 can potentially target cancer stem cells to overcome drug resistance

Bile acids induce MUC2 overexpression in human colon carcinoma cells

COX-2 induction by unconjugated bile acids involves reactive oxygen species-mediated signalling pathways in Barrett's oesophagus and oesophageal adenocarcinoma

Cancer stem cells in esophageal cancer and response to therapy

Cancer stem cells: the promise and the potential.

Chk1 inhibition potentiates the therapeutic efficacy of PARP inhibitor BMN673 in gastric cancer

Clinical and genomic landscape of gastric cancer with a mesenchymal phenotype.

Current status of ramucirumab in gastroesophageal adenocarcinoma.

Dysfunctional transforming growth factor-β signaling with constitutively active Notch signaling in Barrett's esophageal adenocarcinoma

Exploiting Molecular and Immune Biology of Gastric and Gastroesophageal Adenocarcinomas to Discover Novel Therapeutic Targets.

Factors Associated with Resection and Survival After Laparoscopic HIPEC for Peritoneal Gastric Cancer Metastasis

Galectin-3 Mediates Tumor Cell-Stroma Interactions by Activating Pancreatic Stellate Cells to Produce Cytokines via Integrin Signaling.

Galectin-3 expression is prognostic in diffuse type gastric adenocarcinoma, confers aggressive phenotype, and can be targeted by YAP1/BET inhibitors

Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity ⬇️

Galectin-3 modulates MUC2 mucin expression in human colon cancer cells at the level of transcription via AP-1 activation

Gastric adenocarcinoma.

Gastric cancer-molecular and clinical dimensions

Genetic alterations and expression characteristics of ARID1A impact tumor immune contexture and survival in early-onset gastric cancer

H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer

Hippo coactivator YAP1 upregulates SOX9 and endows esophageal cancer cells with stem-like properties

Induction of MUC5AC mucin by conjugated bile acids in the esophagus involves the phosphatidylinositol 3-kinase/protein kinase C/activator protein-1 pathway

Inhibition of the ATM/Chk2 axis promotes cGAS/STING signaling in ARID1A-deficient tumors

Integrated genomic profiling and modelling for risk stratification in patients with advanced oesophagogastric adenocarcinoma

Introduction

Is phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway therapeutic target for esophageal adenocarcinoma

Large tumor suppressor homologs 1 and 2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZ.

Liquid biopsies in gastrointestinal malignancies: when is the big day?

LncRNA PVT1 Is a Poor Prognosticator and Can Be Targeted by PVT1 Antisense Oligos in Gastric Adenocarcinoma

LncRNA PVT1 up-regulation is a poor prognosticator and serves as a therapeutic target in esophageal adenocarcinoma

Loss of TGF-β adaptor β2SP activates notch signaling and SOX9 expression in esophageal adenocarcinoma

Medical management of gastric cancer: a 2014 update

Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancer

Molecular biology and immunology of gastric cancer peritoneal metastasis

Molecular biomarkers in gastric cancer.

Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response

Nuclear expression of Gli-1 is predictive of pathologic complete response to chemoradiation in trimodality treated oesophageal cancer patients.

Overexpressed Galectin-3 in Pancreatic Cancer Induces Cell Proliferation and Invasion by Binding Ras and Activating Ras Signaling ⬇️

PPARδ Interacts with the Hippo Coactivator YAP1 to Promote SOX9 Expression and Gastric Cancer Progression

Phase I Trial of Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) with Cisplatin, Mitomycin, and Paclitaxel in Patients with Gastric Adenocarcinoma and Associated Carcinomatosis or Positive Cytology

Polyphenon E inhibits the growth of human Barrett's and aerodigestive adenocarcinoma cells by suppressing cyclin D1 expression

Post-trimodality expression levels of metadherin (MTDH) as a prognostic biomarker for esophageal adenocarcinoma patients.

Potentially functional variants in the core nucleotide excision repair genes predict survival in Japanese gastric cancer patients

Preoperative Therapy for Gastric Adenocarcinoma is Protective for Poor Oncologic Outcomes in Patients with Complications After Gastrectomy

Proteomics approach to identify biomarkers for upper gastrointestinal cancer.

Reply

Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma

Targeting Hippo coactivator YAP1 through BET bromodomain inhibition in esophageal adenocarcinoma

Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGF-β Signaling

The DNA Endonuclease Mus81 Regulates ZEB1 Expression and Serves as a Target of BET4 Inhibitors in Gastric Cancer

The Hippo Coactivator YAP1 Mediates EGFR Overexpression and Confers Chemoresistance in Esophageal Cancer

The Long Noncoding RNA CCAT2 induces chromosomal instability through BOP1 - AURKB signaling

The role of hedgehog signaling in gastric cancer: molecular mechanisms, clinical potential, and perspective

Translating genomic profiling to gastrointestinal cancer treatment

Tumor-associated macrophage infiltration is highly associated with PD-L1 expression in gastric adenocarcinoma.

YAP1 mediates gastric adenocarcinoma peritoneal metastases that are attenuated by YAP1 inhibition

YAP1-Mediated CDK6 Activation Confers Radiation Resistance in Esophageal Cancer - Rationale for the Combination of YAP1 and CDK4/6 Inhibitors in Esophageal Cancer

Yield of peritoneal cytology in staging patients with gastric and gastroesophageal cancer

iTALK: an R Package to Characterize and Illustrate Intercellular Communication