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List of works by Edward M Behrens

2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Coll

scientific article published on 28 August 2015

2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Coll

scientific article published on March 2016

American College of Rheumatology Clinical Guidance for Pediatric Patients with Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with SARS-CoV-2 and Hyperinflammation in COVID-19. Version 1

scientific article published on 23 July 2020

American College of Rheumatology Clinical Guidance for Pediatric Patients with Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with SARS-CoV-2 and Hyperinflammation in COVID-19. Version 2

scientific article published on 05 December 2020

Association of the TRAF1-C5 locus on chromosome 9 with juvenile idiopathic arthritis

scientific article published on 01 July 2008

Brief Report: Interferon-γ-Mediated Immunopathology Potentiated by Toll-Like Receptor 9 Activation in a Murine Model of Macrophage Activation Syndrome

scientific article published on 24 November 2018

Brief report: alternative activation of laser-captured murine hemophagocytes.

scientific article

Complement receptor 3 ligation of dendritic cells suppresses their stimulatory capacity

scientific article published in May 2007

Convalescent plasma for pediatric patients with SARS-CoV-2-associated acute respiratory distress syndrome

scientific article published on 04 September 2020

Deep Immune Profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19

scientific article published on 27 September 2020

Diagnostic biomarkers to differentiate sepsis from cytokine release syndrome in critically ill children

scientific article published on 01 October 2020

Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases

scientific article published on 01 April 2020

Distinguishing Multisystem Inflammatory Syndrome in Children From Kawasaki Disease and Benign Inflammatory Illnesses in the SARS-CoV-2 Pandemic

scientific article published on 22 September 2020

Emergent high fatality lung disease in systemic juvenile arthritis

scientific article published on 27 September 2019

Evaluation of the presentation of systemic onset juvenile rheumatoid arthritis: data from the Pennsylvania Systemic Onset Juvenile Arthritis Registry (PASOJAR).

scientific article

Evidence of thrombotic microangiopathy in children with SARS-CoV-2 across the spectrum of clinical presentations

scientific article published on 01 December 2020

Expert consensus on dynamics of laboratory tests for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.

scientific article published on 19 January 2016

Genetic Deficiency of Interferon-γ Reveals Interferon-γ-Independent Manifestations of Murine Hemophagocytic Lymphohistiocytosis

scientific article published on 15 December 2019

Genetic defects in cytolysis in macrophage activation syndrome.

scientific article published on January 2014

Genetic sharing and heritability of paediatric age of onset autoimmune diseases.

scientific article

How to use... antinuclear antibodies in paediatric rheumatic diseases

scientific article published on 01 April 2013

Human Adenovirus 7-Associated Hemophagocytic Lymphohistiocytosis-Like Illness: Clinical and Virological Characteristics in a Cluster of Five Pediatric Cases

scientific article published on 31 August 2020

Hyperinflammation, rather than hemophagocytosis, is the common link between macrophage activation syndrome and hemophagocytic lymphohistiocytosis

scientific article published on September 2014

IL-10 distinguishes a unique population of activated, effector-like CD8+ T cells in murine acute liver inflammation.

scientific article

IL-10 is a critical negative regulator of macrophage activation syndrome.

scientific article

IL-4 suppresses dendritic cell response to type I interferons.

scientific article published in November 2007

Interferon-γ mediates anemia but is dispensable for fulminant toll-like receptor 9-induced macrophage activation syndrome and hemophagocytosis in mice

scientific article published on July 2013

Interleukin 1 receptor antagonist to treat cytophagic histiocytic panniculitis with secondary hemophagocytic lymphohistiocytosis

scientific article published on 01 October 2006

Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis

scientific article

Juvenile idiopathic arthritis classification criteria: loopholes and diagnosis software.

scientific article published in January 2007

Kill or be killed

scientific article published on 01 June 2015

Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibition.

scientific article

Making sense of the cytokine storm: a conceptual framework for understanding, diagnosing, and treating hemophagocytic syndromes

scientific article

Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases

scientific article

Microbiota-dependent signals are required to sustain TLR-mediated immune responses

article

Monomethylfumarate Ameliorates Murine Macrophage Activation Syndrome in Both Heme Oxygenase 1-dependent and -independent Manners

scientific article published on 15 November 2020

Multisystem inflammatory syndrome in children and COVID-19 are distinct presentations of SARS-CoV-2

scientific article published on 30 July 2020

Not all hemophagocytes are created equally: appreciating the heterogeneity of the hemophagocytic syndromes

scientific article published on January 2012

Occult macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis.

scientific article published on March 2007

On the alert for cytokine storm: Immunopathology in COVID-19

scientific article published on 15 April 2020

Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part two: Genoa, Italy. 28 September – 01 October 2016.

scientific article published on 30 May 2017

Repeated TLR9 stimulation results in macrophage activation syndrome-like disease in mice.

scientific article

Reply

scientific article published on 29 April 2017

Review: Cytokine Storm Syndrome: Looking Toward the Precision Medicine Era.

scientific article published on 19 February 2017

SARS-CoV-2 antibody responses in children with MIS-C and mild and severe COVID-19

scientific article published on 18 August 2020

SARS-CoV-2 antibody responses in children with MIS-C and mild and severe COVID-19

scientific article published on 02 December 2020

ST2 contributes to T-cell hyperactivation and fatal hemophagocytic lymphohistiocytosis in mice

scientific article published on 30 October 2015

Site-specific accumulation of recently activated CD4+ Foxp3+ regulatory T cells following adoptive transfer.

scientific article published on June 2012

Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: case series with 12 patients

scientific article published on 07 August 2010

TLR9-mediated inflammation drives a Ccr2-independent peripheral monocytosis through enhanced extramedullary monocytopoiesis

scientific article published on 12 September 2016

The ζ isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling

scientific article

Toll-like receptor 9 and interferon-γ receptor signaling suppress the B-cell fate of uncommitted progenitors in mice

scientific article published on 26 February 2015

Tyrosine 870 of TLR9 is critical for receptor maturation rather than phosphorylation-dependent ligand-induced signaling

scientific article published in PLoS ONE

Variants in CXCR4 associate with juvenile idiopathic arthritis susceptibility

scientific article

Weathering the storm: Improving therapeutic interventions for cytokine storm syndromes by targeting disease pathogenesis.

scientific article published on 7 February 2017

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