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List of works by Atsushi Shimizu

12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population

scientific article published on 27 September 2019

3.5KJPNv2: an allele frequency panel of 3552 Japanese individuals including the X chromosome

scientific article published on 18 June 2019

A GWAS identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21

scientific article published on 31 October 2018

A comparison of genome cohort participants' genetic knowledge and preferences to receive genetic results before and after a genetics workshop

scientific article published on 05 September 2018

A genome-wide association study for highly sensitive cardiac troponin T levels identified a novel genetic variation near a RBAK-ZNF890P locus in the Japanese general population

scientific article published on 12 December 2020

A genome-wide association study in Japanese identified one variant associated with a preference for a Japanese dietary pattern

scientific article published on 06 December 2020

A genome-wide association study in the Japanese population identifies the 12q24 locus for habitual coffee consumption: The J-MICC Study

scientific article

A genome-wide association study on fish consumption in a Japanese population-the Japan Multi-Institutional Collaborative Cohort study

scientific article published on 07 September 2020

A homozygous nonsense mutation in the gene for Tmem79, a component for the lamellar granule secretory system, produces spontaneous eczema in an experimental model of atopic dermatitis

scientific journal article

A novel giant gene CSMD3 encoding a protein with CUB and sushi multiple domains: a candidate gene for benign adult familial myoclonic epilepsy on human chromosome 8q23.3-q24.1.

scientific article published on September 2003

A physical map of the human genome

scientific article

ALDH2 genotype modulates the association between alcohol consumption and AST/ALT ratio among middle-aged Japanese men: a genome-wide G × E interaction analysis

scientific article published on 01 October 2020

Adjustment of Cell-Type Composition Minimizes Systematic Bias in Blood DNA Methylation Profiles Derived by DNA Collection Protocols

scientific article published on 22 January 2016

Altered stratum corneum barrier and enhanced percutaneous immune responses in filaggrin-null mice

scientific article published on 10 March 2012

Analysis of eighteen deletion breakpoints in the parkin gene

scientific article

Assessment of homozygosity levels in the mito-gynogenetic torafugu (Takifugu rubripes) by genome-wide SNP analyses

scientific article published in 2013

Association Between Glycemic Traits and Primary Open-Angle Glaucoma: A Mendelian Randomization Study in the Japanese Population

scientific article published in 2023

Author Correction: Characterizing rare and low-frequency height-associated variants in the Japanese population

scientific article published on 09 March 2020

Canine hair-follicle keratinocytes enriched with bulge cells have the highly proliferative characteristic of stem cells.

scientific article

Characterization of brown adipose tissue thermogenesis in the naked mole-rat (Heterocephalus glaber), a heterothermic mammal

scientific article published on 10 November 2020

Characterizing rare and low-frequency height-associated variants in the Japanese population

scientific article published on 27 September 2019

Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): rationale, progress and perspective

scientific article published on 01 February 2020

Comparative genomics of the keratin-associated protein (KAP) gene clusters in human, chimpanzee, and baboon

scientific article published in March 2004

Diverse spectrum of rare deafness genes underlies early-childhood hearing loss in Japanese patients: a cross-sectional, multi-center next-generation sequencing study

scientific article

Dramatic improvement in genome assembly achieved using doubled-haploid genomes

scientific article

Epigenome-Wide Association Study Identifies a Novel DNA Methylation in Patients With Severe Aortic Valve Stenosis

scientific article published on 12 January 2020

Establishment of HRAS(G12V) transgenic medaka as a stable tumor model for in vivo screening of anticancer drugs

scientific article

Evaluation of clinical formalin-fixed paraffin-embedded tissue quality for targeted-bisulfite sequencing

scientific article published on 17 December 2020

Experimental evaluation of ebastine, a second-generation anti-histamine, as a supportive medication for alopecia areata.

scientific article published on 23 March 2010

Fast skeletal muscle myosin heavy chain gene cluster of medaka Oryzias latipes enrolled in temperature adaptation

scientific article published on 16 January 2007

GWAS identifies nine nephrolithiasis susceptibility loci related with metabolic and crystallization pathways

GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.

scientific article published on 17 February 2018

Genetic Predisposition to Ischemic Stroke: A Polygenic Risk Score

scientific article published on 29 December 2016

Genome analyses for the Tohoku Medical Megabank Project towards establishment of personalized healthcare

article

Genome-Wide Polygenic Score and the Risk of Ischemic Stroke in a Prospective Cohort: The Hisayama Study

scientific article published on 31 January 2020

Genome-wide Association Study of Leisure-Time Exercise Behavior in Japanese Adults

scientific article

Genome-wide analysis of polymorphism × sodium interaction effect on blood pressure identifies a novel 3'-BCL11B gene desert locus

scientific article published in Scientific Reports

Genome-wide association meta-analysis and Mendelian randomization analysis confirm ALDH2 influencing on sleep duration in the Japanese population

scientific article published on 01 June 2019

Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer

scientific article published on 24 June 2020

Genome-wide association study (GWAS) of ovarian cancer in Japanese predicted regulatory variants in 22q13.1

scientific article published in PLoS ONE

Genome-wide association study identifies 112 new loci for body mass index in the Japanese population.

scientific article published on 11 September 2017

Genome-wide identification of inter-individually variable DNA methylation sites improves the efficacy of epigenetic association studies.

scientific article published on 13 April 2017

Genome-wide meta-analysis in Japanese populations identifies novel variants at the TMC6-TMC8 and SIX3-SIX2 loci associated with HbA1c

scientific article published on 23 November 2017

Genomic sequences encoding two types of medaka hemopexin-like protein Wap65, and their gene expression profiles in embryos

scientific article

Global gene expression analysis following spinal cord injury in non-human primates

scientific article published on 27 May 2014

Histopathological and electron microscopic study in dogs with patellar luxation and skin hyperextensibility

scientific article published on 06 July 2018

Hyper-expansion of large DNA segments in the genome of kuruma shrimp, Marsupenaeus japonicus

scientific article

Identification of a novel uterine leiomyoma GWAS locus in a Japanese population

scientific article published on 27 January 2020

Identification of mutations in the prostaglandin transporter gene SLCO2A1 and its phenotype-genotype correlation in Japanese patients with pachydermoperiostosis

scientific article published on 27 July 2012

Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population

scientific article published on 22 November 2019

IgG binds to desmoglein 3 in desmosomes and causes a desmosomal split without keratin retraction in a pemphigus mouse model

scientific article published on May 2004

In vivo ultrastructural localization of the desmoglein 3 adhesive interface to the desmosome mid-line

scientific article published on 01 May 2005

Intraindividual dynamics of transcriptome and genome-wide stability of DNA methylation

scientific article published on 19 May 2016

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases

scientific article published on 08 June 2020

Long-term safety issues of iPSC-based cell therapy in a spinal cord injury model: oncogenic transformation with epithelial-mesenchymal transition

scientific article

Machine learning for effectively avoiding overfitting is a crucial strategy for the genetic prediction of polygenic psychiatric phenotypes

scientific article published on 17 August 2020

Maternal Baseline Characteristics and Perinatal Outcomes: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study

scientific article published on 10 October 2020

Molecular cloning and characterization of gene for Golgi-localized syntaphilin-related protein on human chromosome 8q23.

scientific article

Multiple café au lait spots in familial patients with MAP2K2 mutation.

scientific article

Mutations in SERPINB7, encoding a member of the serine protease inhibitor superfamily, cause Nagashima-type palmoplantar keratosis

scientific article

Myocyte enhancer factor 2 regulates expression of medaka Oryzias latipes fast skeletal myosin heavy chain genes in a temperature-dependent manner

scientific article published on 03 October 2007

Neutrophils contact to plasma membrane of keratinocytes including desmosomal structures in canine pemphigus foliaceus

scientific article published on 01 August 2008

Non-pathogenic pemphigus foliaceus (PF) IgG acts synergistically with a directly pathogenic PF IgG to increase blistering by p38MAPK-dependent desmoglein 1 clustering.

scientific article published on 12 December 2016

Novel Risk Loci Identified in a Genome-Wide Association Study of Urolithiasis in a Japanese Population

scientific article published on 11 April 2019

Population-based biobank participants' preferences for receiving genetic test results

scientific article published on 10 August 2017

Radiation hybrid maps of Medaka chromosomes LG 12, 17, and 22.

scientific article

Reduction of systematic bias in transcriptome data from human peripheral blood mononuclear cells for transportation and biobanking

scientific article

Regional genetic differences among Japanese populations and performance of genotype imputation using whole-genome reference panel of the Tohoku Medical Megabank Project

scientific article published on 24 July 2018

Removal of amino-terminal extracellular domains of desmoglein 1 by staphylococcal exfoliative toxin is sufficient to initiate epidermal blister formation

scientific article published on 30 July 2010

Resistance to chemical carcinogenesis induction via a dampened inflammatory response in naked mole-rats

scientific article published on 30 March 2022

Restoration of the intrinsic properties of human dermal papilla in vitro

scientific article published on 23 May 2012

SAMD9 mutations cause a novel multisystem disorder, MIRAGE syndrome, and are associated with loss of chromosome 7.

scientific article

Sequence analysis of filaggrin gene by novel shotgun method in Japanese atopic dermatitis.

scientific article

Sox5 functions as a fate switch in medaka pigment cell development

scientific article

Study profile of The Tohoku Medical Megabank Community-Based Cohort Study

scientific article published on 11 January 2020

Subcellular localization of desmosomal components is different between desmoglein3 knockout mice and pemphigus vulgaris model mice

scientific article published on 13 June 2009

The Tohoku Medical Megabank Project: Design and Mission

scientific article published on 02 July 2016

The disruption of Sox21-mediated hair shaft cuticle differentiation causes cyclic alopecia in mice

scientific article

The genome size evolution of medaka (Oryzias latipes) and fugu (Takifugu rubripes).

scientific article

The interaction between ABCA1 polymorphism and physical activity on the HDL-cholesterol levels in a Japanese population

scientific article published on 06 November 2019

The medaka draft genome and insights into vertebrate genome evolution

scientific article

The medaka zic1/zic4 mutant provides molecular insights into teleost caudal fin evolution

scientific article published in March 2012

The minimal eukaryotic ribosomal DNA units in the primitive red alga Cyanidioschyzon merolae

scientific article

The use of next-generation sequencing in molecular diagnosis of neurofibromatosis type 1: a validation study.

scientific article

Tumour resistance in induced pluripotent stem cells derived from naked mole-rats.

scientific article

UTGB/medaka: genomic resource database for medaka biology

scientific article

Ultrastructural changes in mice actively producing antibodies to desmoglein 3 parallel those in patients with pemphigus vulgaris

scientific article

Versican is crucial for the initiation of cardiovascular lumen development in medaka (Oryzias latipes)

scientific article published on 01 July 2019

YPEL5 protein of the YPEL gene family is involved in the cell cycle progression by interacting with two distinct proteins RanBPM and RanBP10.

scientific article

dbTMM: an integrated database of large-scale cohort, genome and clinical data for the Tohoku Medical Megabank Project

scientific article published on 10 December 2021

f-treeGC: a questionnaire-based family tree-creation software for genetic counseling and genome cohort studies

scientific article

iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation.

scientific article

jMorp updates in 2020: large enhancement of multi-omics data resources on the general Japanese population

scientific article published on 12 November 2020

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