List of works - Jeremy Sanderson

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

scientific article

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

scientific article

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

scientific article

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scientific journal article

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

scientific article (publication date: July 2007)

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

scientific article

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

scientific article

The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease

scientific article

High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease

scientific article

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

scientific article published on 27 April 2008

Mycobacterium paratuberculosis DNA in Crohn's disease tissue

scientific article

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.

scientific article published on 9 January 2017

A Nonsynonymous SNP in ATG16L1 Predisposes to Ileal Crohn’s Disease and Is Independent of CARD15 and IBD5

scientific article

Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase).

scientific article

Review article: lactose intolerance in clinical practice--myths and realities.

scientific article

Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

scientific article

Randomised, double-blind, placebo-controlled trial of fructo-oligosaccharides in active Crohn's disease

scientific article published on 24 January 2011

Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease

scientific article published in October 2002

Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies

scientific article published on 25 April 2013

IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease

scientific article

Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship

scientific article

Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data

scientific article

Gastrointestinal microbiota in irritable bowel syndrome: their role in its pathogenesis and treatment

scientific article published on 29 May 2008

Smokers with active Crohn's disease have a clinically relevant dysbiosis of the gastrointestinal microbiota.

scientific article

Distinct microbial populations exist in the mucosa-associated microbiota of sub-groups of irritable bowel syndrome

scientific article published on 09 November 2011

Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease

scientific article

Genetic variation in myosin IXB is associated with ulcerative colitis

scientific article

Pharmacogenetic variants in the DPYD, TYMS, CDA and MTHFR genes are clinically significant predictors of fluoropyrimidine toxicity

scientific article published on 04 June 2013

Prospective evaluation of the pharmacogenetics of azathioprine in the treatment of inflammatory bowel disease

scientific article published on 01 October 2008

Low-dose azathioprine or mercaptopurine in combination with allopurinol can bypass many adverse drug reactions in patients with inflammatory bowel disease

scientific article

Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease

scientific article

Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease.

scientific article

Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and Inflammatory Bowel Disease and their effects on disease behavior: A case-control and meta-analysis study

article

The ITPA c.94C>A and g.IVS2+21A>C sequence variants contribute to missplicing of the ITPA gene

scientific article

Long-term outcome of using allopurinol co-therapy as a strategy for overcoming thiopurine hepatotoxicity in treating inflammatory bowel disease

scientific article published in September 2008

Review article: malignancy on thiopurine treatment with special reference to inflammatory bowel disease

scientific article published on 16 April 2010

Gut-associated lymphoid tissue contains the molecular machinery to support T-cell-dependent and T-cell-independent class switch recombination.

scientific article published on 9 September 2009

The mechanisms and efficacy of probiotics in the prevention of Clostridium difficile-associated diarrhoea

scientific article published on April 2009

Thiopurine methyltransferase: should it be measured before commencing thiopurine drug therapy?

scientific article published in July 2004

Novel pharmacogenetic markers for treatment outcome in azathioprine-treated inflammatory bowel disease

scientific article

Mechanism of allopurinol induced TPMT inhibition

scientific article published on 14 June 2013

Optimising outcome on thiopurines in inflammatory bowel disease by co-prescription of allopurinol

scientific article published on 3 March 2012

Association of DLG5 R30Q variant with inflammatory bowel disease

scientific article (publication date: July 2005)

Characterization of virus-like particles associated with the human faecal and caecal microbiota

scientific article

Estimating risks of common complex diseases across genetic and environmental factors: the example of Crohn disease.

scientific article published on 27 July 2007

Assessment of thiopurine methyltransferase enzyme activity is superior to genotype in predicting myelosuppression following azathioprine therapy in patients with inflammatory bowel disease

scientific article published on 01 May 2007

Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes

scientific article

A role for gut-associated lymphoid tissue in shaping the human B cell repertoire

scientific article published on August 12, 2013

Mutation in the ITPA gene predicts intolerance to azathioprine

scientific article

Small bowel MR enterography: problem solving in Crohn's disease

scientific article published on 17 March 2012

List of works by Jeremy Sanderson

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease

High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

Mycobacterium paratuberculosis DNA in Crohn's disease tissue

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.

A Nonsynonymous SNP in ATG16L1 Predisposes to Ileal Crohn’s Disease and Is Independent of CARD15 and IBD5

Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase).

Review article: lactose intolerance in clinical practice--myths and realities.

Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

Randomised, double-blind, placebo-controlled trial of fructo-oligosaccharides in active Crohn's disease

Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease

Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies

IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease

Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship

Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data

Gastrointestinal microbiota in irritable bowel syndrome: their role in its pathogenesis and treatment

Smokers with active Crohn's disease have a clinically relevant dysbiosis of the gastrointestinal microbiota.

Distinct microbial populations exist in the mucosa-associated microbiota of sub-groups of irritable bowel syndrome

Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease

Genetic variation in myosin IXB is associated with ulcerative colitis

Pharmacogenetic variants in the DPYD, TYMS, CDA and MTHFR genes are clinically significant predictors of fluoropyrimidine toxicity

Prospective evaluation of the pharmacogenetics of azathioprine in the treatment of inflammatory bowel disease

Low-dose azathioprine or mercaptopurine in combination with allopurinol can bypass many adverse drug reactions in patients with inflammatory bowel disease

Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease

Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease.

Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and Inflammatory Bowel Disease and their effects on disease behavior: A case-control and meta-analysis study

The ITPA c.94C>A and g.IVS2+21A>C sequence variants contribute to missplicing of the ITPA gene

Long-term outcome of using allopurinol co-therapy as a strategy for overcoming thiopurine hepatotoxicity in treating inflammatory bowel disease

Review article: malignancy on thiopurine treatment with special reference to inflammatory bowel disease

Gut-associated lymphoid tissue contains the molecular machinery to support T-cell-dependent and T-cell-independent class switch recombination.

The mechanisms and efficacy of probiotics in the prevention of Clostridium difficile-associated diarrhoea

Thiopurine methyltransferase: should it be measured before commencing thiopurine drug therapy?

Novel pharmacogenetic markers for treatment outcome in azathioprine-treated inflammatory bowel disease

Mechanism of allopurinol induced TPMT inhibition

Optimising outcome on thiopurines in inflammatory bowel disease by co-prescription of allopurinol

Association of DLG5 R30Q variant with inflammatory bowel disease

Characterization of virus-like particles associated with the human faecal and caecal microbiota

Estimating risks of common complex diseases across genetic and environmental factors: the example of Crohn disease.

Assessment of thiopurine methyltransferase enzyme activity is superior to genotype in predicting myelosuppression following azathioprine therapy in patients with inflammatory bowel disease

Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes

A role for gut-associated lymphoid tissue in shaping the human B cell repertoire

Mutation in the ITPA gene predicts intolerance to azathioprine

Small bowel MR enterography: problem solving in Crohn's disease