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List of works by Cristina Mussini

A frailty index predicts survival and incident multimorbidity independent of markers of HIV disease severity

scientific article published on August 2015

A prospective randomized trial on abacavir/lamivudine plus darunavir/ritonavir or raltegravir in HIV-positive drug-naïve patients with CD4<200 cells/uL (the PRADAR study)

scientific article published on 27 September 2019

Access and response to direct antiviral agents (DAA) in HIV-HCV co-infected patients in Italy: Data from the Icona cohort

scientific article

Acute human herpes virus 7 (HHV-7) encephalitis in an immunocompetent adult patient: a case report and review of literature.

scientific article published on 6 April 2017

Aging with HIV infection: a journey to the center of inflammAIDS, immunosenescence and neuroHIV.

scientific article published on July 2014

All-cause mortality in treated HIV-infected adults with CD4 ≥500/mm3 compared with the general population: evidence from a large European observational cohort collaboration

scientific article published on 28 November 2011

An observational comparison of first-line combination antiretroviral treatment (cART) with 2NRTI and ATV/r or DRV/r in HIV-infected patients in Italy

scientific article published on 2 November 2014

Analysis of inflammasomes and antiviral sensing components reveals decreased expression of NLRX1 in HIV-positive patients assuming efficient antiretroviral therapy

scientific article

Bloodstream infections caused by carbapenem-resistant Acinetobacter baumannii: Clinical features, therapy and outcome from a multicenter study

scientific article published on 28 May 2019

CD4 cell-monitored treatment interruption in patients with a CD4 cell count > 500 x 106 cells/l.

scientific article published on February 2005

CD4+ T-cell differentiation, regulatory T cells and gag-specific T lymphocytes are unaffected by CD4-guided treatment interruption and therapy resumption

scientific article published in July 2011

CD4/CD8 ratio normalisation and non-AIDS-related events in individuals with HIV who achieve viral load suppression with antiretroviral therapy: an observational cohort study

scientific article published on 6 February 2015

Calendar time trends in the incidence and prevalence of triple-class virologic failure in antiretroviral drug-experienced people with HIV in Europe

scientific article published on March 2012

Ceftolozane/Tazobactam for Treatment of Severe ESBL-Producing Enterobacterales Infections: A Multicenter Nationwide Clinical Experience (CEFTABUSE II Study)

scientific article published on 21 April 2020

Ceftolozane/tazobactam for the treatment of serious P. aeruginosa infections: a multicenter nationwide clinical experience

Ceftolozane/tazobactam for the treatment of serious Pseudomonas aeruginosa infections: a multicentre nationwide clinical experience

scholarly article by Matteo Bassetti et al published April 2019 in International Journal of Antimicrobial Agents

Characterisation of HIV-1 molecular transmission clusters among newly diagnosed individuals infected with non-B subtypes in Italy

scientific article published on 10 May 2019

Chronic Hepatitis B and C Virus Infection and Risk for Non-Hodgkin Lymphoma in HIV-Infected Patients: A Cohort Study

scientific article

Clinical Efficacy of Ceftolozane-tazobactam Versus Other Active Agents for the Treatment of Bacteremia and Nosocomial Pneumonia Due to Drug resistant P. aeruginosa

scientific article published on 06 January 2020

Clinical Experience with Ceftazidime-Avibactam for the Treatment of Infections due to Multidrug-Resistant Gram-Negative Bacteria Other than Carbapenem-Resistant Enterobacterales

scientific article published on 09 February 2020

Clinical outcomes of two-drug regimens vs. three-drug regimens in antiretroviral treatment-experienced people living with HIV

scientific article published on 23 December 2020

Cohort profile: The Observational cohort for the study of DOlutegravir in Antiretroviral Combination REgimens (ODOACRE)

scientific article published on 02 December 2019

Comparative Evaluation of Subtyping Tools for Surveillance of Newly Emerging HIV-1 Strains

scientific article published on 12 July 2017

Compression of frailty in adults living with HIV

scientific article published on 22 August 2019

Cytometry, immunology, and HIV infection: three decades of strong interactions.

scientific article published on 20 June 2013

Cytotoxic granule release dominates gag-specific CD4+ T-cell response in different phases of HIV infection

scientific article published in April 2010

Death rates in HIV-positive antiretroviral-naive patients with CD4 count greater than 350 cells per microL in Europe and North America: a pooled cohort observational study

scientific article

Decrease of renal function in HCV and HIV/HCV-infected patients with telaprevir-based therapy.

scientific article

Decreased mitochondrial DNA content in subcutaneous fat from HIV-infected women taking antiretroviral therapy as measured at delivery

scientific article published in January 2011

Development and validation of a prediction model for severe respiratory failure in hospitalized patients with SARS-Cov-2 infection: a multicenter cohort study (PREDI-CO study)

scientific article published on 08 August 2020

Differential course of HIV-1 infection and apolipoprotein E polymorphism

scientific article published in January 2007

Discontinuation of Initial Antiretroviral Therapy in Clinical Practice: Moving Toward Individualized Therapy

scientific article published on March 2016

Discontinuation of maintenance therapy for cryptococcal meningitis in patients with AIDS treated with highly active antiretroviral therapy: an international observational study

scientific article published on 29 January 2004

Discontinuation of secondary prophylaxis for Pneumocystis carinii pneumonia in human immunodeficiency virus-infected patients: a randomized trial by the CIOP Study Group

scientific article published on 12 February 2003

Drop in CD4+ counts below 200 cells/µL after reaching (or starting from) values higher than 350 cells/µL in HIV-infected patients with virological suppression

scientific article

Durability and tolerability of first-line regimens including two nucleoside reverse transcriptase inhibitors and raltegravir or ritonavir boosted-atazanavir or -darunavir: data from the ICONA Cohort

article by Antonella d'Arminio Monforte et al published April 2018 in HIV Clinical Trials

Effectiveness, durability, and safety of darunavir/ritonavir in HIV-1-infected patients in routine clinical practice in Italy: a postauthorization noninterventional study

scientific article published on 6 May 2016

Effects of the change from Stavudine to tenofovir in human immunodeficiency virus-infected children treated with highly active antiretroviral therapy: studies on mitochondrial toxicity and thymic function

scientific article published in January 2008

Efficacy of Ceftazidime-avibactam Salvage Therapy in Patients with Infections Caused by KPC-producing Klebsiella pneumoniae

scientific article published on 01 January 2019

Epidemiology and clinical outcome of lower respiratory tract infections by respiratory syncytial virus or parainfluenza virus type 3 in adults receiving treatment for either acute leukemia or severe aplastic anemia: a retrospective single center stu

scientific article published on 25 July 2015

Features of 'CD4-exploders', HIV-positive patients with an optimal immune reconstitution after potent antiretroviral therapy

scientific article published in August 2002

Genetic divergence of HIV-1 B subtype in Italy over the years 2003-2016 and impact on CTL escape prevalence

scientific article published in Scientific Reports

Genetic polymorphisms of Fas (CD95) and Fas ligand (CD178) influence the rise in CD4+ T cell count after antiretroviral therapy in drug-naïve HIV-positive patients

scientific article published on 13 September 2005

Genotypic Tropism Testing in HIV-1 Proviral DNA Can Provide Useful Information at Low-Level Viremia

scientific article

Genotypic resistance test in proviral DNA can identify resistance mutations never detected in historical genotypic test in patients with low level or undetectable HIV-RNA.

scientific article published on 18 July 2016

Granulicatella adiacens and Abiotrophia defectiva Native Vertebral Osteomyelitis: Three Cases and Literature Review of Clinical Characteristics and Treatment Approach.

scientific article published on 6 May 2019

HIV-1 Infection and the Aging of the Immune System: Facts, Similarities and Perspectives

scientific article published in August 2011

HIV-DNA content in different CD4+ T-cell subsets correlates with CD4+ cell :  CD8+ cell ratio or length of efficient treatment.

scientific article

Highly active antiretroviral therapy restores CD4+ Vbeta T-cell repertoire in patients with primary acute HIV infection but not in treatment-naive HIV+ patients with severe chronic infection

scientific article published in March 2004

Identification and characterization of an aspartyl protease from Cryptococcus neoformans

scientific article published on 16 July 2007

Immunophenotype of HIV+ patients during CD4 cell-monitored treatment interruption: role of the IL-7/IL-7 receptor system

scientific article published in October 2006

Impact of genotypic susceptibility score on cART outcomes during primary HIV infection

scientific article published on 27 June 2019

Impact of lamivudine on the risk of liver-related death in 2,041 HBsAg- and HIV-positive individuals: results from an inter-cohort analysis

scientific article

Impact of pre-therapy viral load on virological response to modern first-line HAART.

scientific article published on 23 January 2013

Impact of social determinants on antiretroviral therapy access and outcomes entering the era of universal treatment for people living with HIV in Italy.

scientific article published on 13 July 2018

Improved darunavir genotypic mutation score predicting treatment response for patients infected with HIV-1 subtype B and non-subtype B receiving a salvage regimen

scientific article published on 28 January 2016

Incidence, timing, and determinants of bacterial pneumonia among HIV-infected patients: data from the ICONA Foundation Cohort

scientific article

Increased plasma levels of extracellular mitochondrial DNA during HIV infection: A new role for mitochondrial damage-associated molecular patterns during inflammation

scientific article published in September 2011

Intact parathyroid hormone levels are associated with increased carotid intima media thickness in HIV infected patients

scientific article

Inverse correlation between vascular calcification and bone mineral density in human immunodeficiency virus-infected patients.

scientific article

Is it safe to discontinue primary Pneumocystis jiroveci pneumonia prophylaxis in patients with virologically suppressed HIV infection and a CD4 cell count <200 cells/microL?

scientific article published in September 2010

Is there any potential for first-line etravirine use? Analysis from a large data set of antiretroviral therapy-naive HIV-infected patients undergoing resistance test

scientific article published in January 2010

Italian guidelines for the use of antiretroviral agents and the diagnostic-clinical management of HIV-1 infected persons. Update 2015.

scientific article published on February 2016

Italian guidelines for the use of antiretroviral agents and the diagnostic-clinical management of HIV-1 infected persons. Update 2016.

scientific article published on April 2017

Italian guidelines for the use of antiretroviral agents and the diagnostic-clinical management of HIV-1 infected persons. Update December 2014.

scientific article published on July 2015

Kinetics of CD4 cells after discontinuation of antiretroviral therapy in patients with virological failure and a CD4 cell count greater than 500 cells/microl

scientific article

Late presenters in new HIV diagnoses from an Italian cohort of HIV-infected patients: prevalence and clinical outcome

scientific article published on January 2011

Liver enzyme elevation during darunavir-based antiretroviral treatment in HIV-1-infected patients with or without hepatitis C coinfection: data from the ICONA foundation cohort

scientific article

Long-term CD4+ T-cell count evolution after switching from regimens including HIV nucleoside reverse transcriptase inhibitors (NRTI) plus protease inhibitors to regimens containing NRTI plus non-NRTI or only NRTI

scientific article

Low Frequency of Severe Hepatotoxicity and Association With HCV Coinfection in HIV-Positive Patients Treated With HAART

article

MDR1 C3435T genetic polymorphism does not influence the response to antiretroviral therapy in drug-naive HIV-positive patients

scientific article published in July 2003

Managing the long surviving HIV patient: a proposal for a multidimensional first-level diagnostic assessment

article

Mitochondrial DNA Haplogroups and Incidence of Lipodystrophy in HIV-Infected Patients on Long-Term Antiretroviral Therapy

article

Mitochondrial DNA haplogroups and highly active antiretroviral therapy-related lipodystrophy

scientific article published in October 2008

Mitochondrial DNA haplogroups and incidence of lipodystrophy in HIV-infected patients on long-term antiretroviral therapy

article

Mitochondrial changes during D-drug-containing once-daily therapy in HIV-positive treatment-naive patients.

scientific article published in January 2010

Mitochondrial functionality and mitochondrial DNA content in lymphocytes of vertically infected human immunodeficiency virus-positive children with highly active antiretroviral therapy-related lipodystrophy

scientific article published on 17 January 2002

Mortality in Patients With Septic Shock by Multidrug Resistant Bacteria.

scientific article published on January 2017

Mucorales-Specific T Cells in Patients with Hematologic Malignancies

scientific article published on 12 February 2016

Novel genetic association of TNF-α-238 and PDCD1-7209 polymorphisms with long-term non-progressive HIV-1 infection.

scientific article published on 10 February 2013

One-pill once-a-day HAART: a simplification strategy that improves adherence and quality of life of HIV-infected subjects

scientific article

Patients presenting with AIDS in the HAART era: a collaborative cohort analysis

scientific article

Performance of genotypic tropism testing in clinical practice using the enhanced sensitivity version of Trofile as reference assay: results from the OSCAR Study Group

scientific article

Persistent disparities in antiretroviral treatment (ART) coverage and virological suppression across Europe, 2004 to 2015

Persistent inflammation in HIV infection: established concepts, new perspectives

scientific article

Physician estimates of adherence and the patient-physician relationship as a setting to improve adherence to antiretroviral therapy

scientific article

Predicting the magnitude of short-term CD4+ T-cell recovery in HIV-infected patients during first-line highly active antiretroviral therapy

scientific article published in January 2010

Predictive Value of Intracellular HIV-1 DNA Levels During CD4-Guided Treatment Interruption in HIV+ Patients

article

Predictors of CD4+ T-Cell Counts of HIV Type 1–Infected Persons After Virologic Failure of All 3 Original Antiretroviral Drug Classes ⬇️

scientific article published on 07 December 2012

Predictors of trend in CD4-positive T-cell count and mortality among HIV-1-infected individuals with virological failure to all three antiretroviral-drug classes

scientific article published in The Lancet

Prevalence, Associated Factors, and Prognostic Determinants of AIDS‐Related Toxoplasmic Encephalitis in the Era of Advanced Highly Active Antiretroviral Therapy

article

Prognostic Value of the Fibrosis-4 Index in Human Immunodeficiency Virus Type-1 Infected Patients Initiating Antiretroviral Therapy with or without Hepatitis C Virus

scientific article published on 7 December 2015

Refining criteria for selecting candidates for a safe lopinavir/ritonavir or darunavir/ritonavir monotherapy in HIV-infected virologically suppressed patients

scientific article

Reliable and accurate CD4+ T cell count and percent by the portable flow cytometer CyFlow MiniPOC and "CD4 Easy Count Kit-Dry", as revealed by the comparison with the gold standard dual platform technology.

scientific article

Resistance detected in PBMCs predicts virological rebound in HIV-1 suppressed patients switching treatment

scientific article published on 03 April 2018

Risk of developing specific AIDS-defining illnesses in patients coinfected with HIV and hepatitis C virus with or without liver cirrhosis

scientific article published on August 2009

Stable changes in CD4+ T lymphocyte miRNA expression after exposure to HIV-1

article

Survival outcomes and effect of early vs. deferred cART among HIV-infected patients diagnosed at the time of an AIDS-defining event: a cohort analysis

scientific article

Switching to dual/monotherapy determines an increase in CD8+ in HIV-infected individuals: an observational cohort study.

scientific article

T cell activation but not polyfunctionality after primary HIV infection predicts control of viral load and length of the time without therapy.

scientific article

Th1 and Th17 proinflammatory profile characterizes invariant natural killer T cells in virologically suppressed HIV+ patients with low CD4+/CD8+ ratio.

scientific article

The cardiovascular risk management for people living with HIV in Europe: how well are we doing?

scientific article

The degree of HIV-1 amino acid variability is strictly related to different disease progression rates

scientific article published on 17 May 2018

The human immunodeficiency virus (HIV) protease inhibitor indinavir directly affects the opportunistic fungal pathogen Cryptococcus neoformans.

scientific article published on October 2004

The problem of renal function monitoring in patients treated with the novel antiretroviral drugs

scientific article published on May 2014

The protease inhibitor atazanavir triggers autophagy and mitophagy in human preadipocytes.

scientific article published on October 2012

Timing of antiretroviral therapy initiation after a first AIDS-defining event: temporal changes in clinical attitudes in the ICONA cohort

scientific article

Treating HIV disease: back to the patient?

scientific article

Treatment discontinuation in HIV-1-infected individuals starting their first-line HAART after 2008: data from the ICONA Foundation Study Cohort

scientific article

Treatment rate for HCV in the direct acting antivirals era in HIV co-infected patients: data from an italian cohort.

scientific article published on 31 January 2018

Trends in virological and clinical outcomes in individuals with HIV-1 infection and virological failure of drugs from three antiretroviral drug classes: a cohort study

scientific article published on 9 October 2011

Triple-class virologic failure in HIV-infected patients undergoing antiretroviral therapy for up to 10 years

scientific article published in March 2010

Upregulation of nuclear-encoded mitochondrial LON protease in HAART-treated HIV-positive patients with lipodystrophy: implications for the pathogenesis of the disease

scientific article

Uptake and Discontinuation of Integrase Inhibitors (INSTIs) in a Large Cohort Setting

scientific article published on 01 March 2020

Viro-immunological response of drug-naive HIV-1-infected patients starting a first-line regimen with viraemia >500,000 copies/ml in clinical practice

scientific article published on 22 September 2017

Virologic and immunologic outcomes of treatment with integrase inhibitors in a real-world setting: The RESPOND cohort consortium

scientific article published on 31 December 2020

Virological response to salvage therapy in HIV-infected persons carrying the reverse transcriptase K65R mutation

scientific article published in January 2007

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