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List of works by Bruce A Edgar

A Balance of Yki/Sd Activator and E2F1/Sd Repressor Complexes Controls Cell Survival and Affects Organ Size

scientific article published in December 2017

A characterization of the effects of Dpp signaling on cell growth and proliferation in the Drosophila wing

scientific article published in February 2002

A double-assurance mechanism controls cell cycle exit upon terminal differentiation in Drosophila

scientific article published in April 2007

A robust cell cycle control mechanism limits E2F-induced proliferation of terminally differentiated cells in vivo

scientific article

ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration

scientific article published on 08 March 2017

Activation of the Tor/Myc signaling axis in intestinal stem and progenitor cells affects longevity, stress resistance and metabolism in drosophila

scientific article published on 29 September 2016

An SH3PX1-Dependent Endocytosis-Autophagy Network Restrains Intestinal Stem Cell Proliferation by Counteracting EGFR-ERK Signaling

scientific article published on 18 April 2019

Brk regulates wing disc growth in part via repression of Myc expression

scientific article

Cell biology. Sizing up the cell

scientific article published on 01 July 2009

Changes in neuronal CycD/Cdk4 activity affect aging, neurodegeneration, and oxidative stress

scientific article

Combinatorial control of temporal gene expression in the Drosophila wing by enhancers and core promoters ⬇️

scientific article published on September 20, 2012

Comparative Generalized Logic Modeling Reveals Differential Gene Interactions during Cell Cycle Exit in Drosophila Wing Development

scientific article published on January 2009

Control of Drosophila endocycles by E2F and CRL4(CDT2).

scientific article published on 30 October 2011

Controlling cell division in yeast and animals: does size matter? ⬇️

scientific article published on April 24, 2003

Cop9 signalosome subunit 8 (CSN8) is essential for Drosophila development

scientific article published in March 2008

Cyclin D does not provide essential Cdk4-independent functions in Drosophila

scientific article

Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut

scientific article

Damage sensing by a Nox-Ask1-MKK3-p38 signaling pathway mediates regeneration in the adult Drosophila midgut

scientific article published on 25 September 2019

Discontinuities in Rap1 activity determine epithelial cell morphology within the developing wing of Drosophila

scientific article

Dpp/Gbb signaling is required for normal intestinal regeneration during infection

scientific article published on 29 December 2014

Drosophila TIF-IA is required for ribosome synthesis and cell growth and is regulated by the TOR pathway

scientific article

Drosophila cyclin D/Cdk4 regulates mitochondrial biogenesis and aging and sensitizes animals to hypoxic stress ⬇️

scientific article published on February 1, 2012

Drosophila cyclin D/Cdk4 requires Hif-1 prolyl hydroxylase to drive cell growth

scientific article published in February 2004

Drosophila's insulin/PI3-kinase pathway coordinates cellular metabolism with nutritional conditions

scientific article published in February 2002

EGFR signaling regulates the proliferation of Drosophila adult midgut progenitors

scientific article published on February 2009

EGFR-dependent TOR-independent endocycles support Drosophila gut epithelial regeneration

scientific article

EGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated Genes

scientific article

EGFR/Ras/MAPK Signaling Mediates Adult Midgut Epithelial Homeostasis and Regeneration in Drosophila ⬇️

scientific article published on December 16, 2010

Egfr/Ras signaling regulates DE-cadherin/Shotgun localization to control vein morphogenesis in the Drosophila wing

scientific article

EndoGI modulates Notch signaling and axon guidance in Drosophila ⬇️

scientific article published on November 3, 2010

Endocycles: a recurrent evolutionary innovation for post-mitotic cell growth.

scientific article published on March 2014

Enhanced expression of thioredoxin-interacting-protein regulates oxidative DNA damage and aging

scholarly article by Tina Oberacker published in July 2018

Escargot maintains stemness and suppresses differentiation in Drosophila intestinal stem cells

scientific article

Filling out the Hippo pathway

scientific article

Fitness trade-offs incurred by ovary-to-gut steroid signalling in Drosophila

scientific article published on 08 July 2020

Flow cytometric analysis of Drosophila cells

scientific article published in January 2008

Fly-FUCCI: A versatile tool for studying cell proliferation in complex tissues.

scientific article published on 13 April 2014

From cell structure to transcription: Hippo forges a new path

scientific article

Genomic analysis of COP9 signalosome function in Drosophila melanogaster reveals a role in temporal regulation of gene expression

scientific article published on 08 May 2007

Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network

scientific article

How flies get their size: genetics meets physiology

scientific article published on December 2006

How size is controlled: from Hippos to Yorkies

scientific article published in November 2007

Hunting complex differential gene interaction patterns across molecular contexts

scientific article published on 29 January 2014

Interactions between Ras1, dMyc, and dPI3K signaling in the developing Drosophila wing

scientific article published on September 2002

Intestinal Stem Cell Pool Regulation in Drosophila

scientific article

Intestinal stem cell function in Drosophila and mice

scientific article published on 19 May 2012

Intestinal stem cells in the adult Drosophila midgut ⬇️

scientific article published on August 11, 2011

Intestinal stem cells: no longer immortal but ever so clever… ⬇️

scientific article published on May 11, 2012

Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phase

scientific article

In Vivo Analysis of Centromeric Proteins Reveals a Stem Cell-Specific Asymmetry and an Essential Role in Differentiated, Non-proliferating Cells.

scientific article published in February 2018

LST8 Regulates Cell Growth via Target-of-Rapamycin Complex 2 (TORC2)

scientific article

LST8 regulates cell growth via target-of-rapamycin complex 2 (TORC2).

scientific article

Lipoic acid and autophagy: new insights into stem cell aging

scientific article published on 27 July 2020

Longer life through an odd Pol enzyme

scientific article published in December 2017

Mammalian cyclin D1/Cdk4 complexes induce cell growth in Drosophila.

scientific article published on 15 March 2006

Mechanisms controlling cell cycle exit upon terminal differentiation

scientific article

Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development

scientific article published on 20 February 2005

Negative regulation of dE2F1 by cyclin-dependent kinases controls cell cycle timing

scientific article published in April 2004

Niche appropriation by Drosophila intestinal stem cell tumours

scientific article

Nutritional control of gene expression in Drosophila larvae via TOR, Myc and a novel cis-regulatory element

scientific article

Polyploidy in tissue homeostasis and regeneration

scientific article published on 18 July 2018

Proliferative control in Drosophila stem cells

scientific article

RNA expression profiling from FACS-isolated cells of the Drosophila intestine.

scientific article published on 13 November 2013

Rap1 maintains adhesion between cells to affect Egfr signaling and planar cell polarity in Drosophila

scientific article published on July 2009

Regional Cell Specific RNA Expression Profiling of FACS Isolated Drosophila Intestinal Cell Populations.

scientific article published on 3 August 2015

Regional Cell-Specific Transcriptome Mapping Reveals Regulatory Complexity in the Adult Drosophila Midgut.

scientific article published on 2 July 2015

Remodelling of oxygen-transporting tracheoles drives intestinal regeneration and tumorigenesis in Drosophila

scientific article published on 10 May 2021

Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins

scientific article

Rheb promotes cell growth as a component of the insulin/TOR signalling network

scientific article

Rheb-TOR signaling promotes protein synthesis, but not glucose or amino acid import, in Drosophila

scientific article

Stimulating cROSstalk between commensal bacteria and intestinal stem cells

scientific article published on 5 November 2013

TOR-mediated autophagy regulates cell death in Drosophila neurodegenerative disease

scientific article published on 31 August 2009

Temporal regulation of Dpp signaling output in the Drosophila wing

scientific article

The Drosophila melanogaster gene brain tumor negatively regulates cell growth and ribosomal RNA synthesis

scientific article published in January 2002

The Drosophila mitochondrial ribosomal protein mRpL12 is required for Cyclin D/Cdk4-driven growth

scientific article

The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration

scientific article

The molecular chaperone Hsp90 is required for cell cycle exit in Drosophila melanogaster

scientific article

The role of translationally controlled tumor protein in proliferation of Drosophila intestinal stem cells

scientific article published on 16 December 2019

The small GTPase Rheb affects central brain neuronal morphology and memory formation in Drosophila

scientific article

The transcriptional repressor dMnt is a regulator of growth in Drosophila melanogaster

scientific article

Tissue design: how Drosophila tumors remodel their neighborhood

scientific article published on 28 March 2014

Tracking protein turnover and degradation by microscopy: photo-switchable versus time-encoded fluorescent proteins

scientific article

Tumor suppressive autophagy in intestinal stem cells controls gut homeostasis

scientific article published on 20 June 2019

Why size matters: altering cell size

scientific article

Yorkie and Scalloped: partners in growth activation

scientific article published in March 2008

dMyc is required for larval growth and endoreplication in Drosophila

scientific article

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