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List of works by Sjoerd H van der Burg

2-Azidoalkoxy-7-hydro-8-oxoadenine derivatives as TLR7 agonists inducing dendritic cell maturation

scientific article

356 Personalized immunotherapy by adoptive T cell transfer during chemotherapy with or without interferon-alpha in patients with recurrent platinum-sensitive epithelial ovarian cancer

scientific article published in 2021

A beneficial tumor microenvironment in oropharyngeal squamous cell carcinoma is characterized by a high T cell and low IL-17(+) cell frequency

scientific article published on 22 February 2016

A framework for T cell assays

scientific article published on 19 October 2015

A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence.

scientific article published on 19 May 2013

A phase 1/2 study combining gemcitabine, Pegintron and p53 SLP vaccine in patients with platinum-resistant ovarian cancer.

scientific article published on 14 August 2015

A placebo-controlled randomized HPV16 synthetic long-peptide vaccination study in women with high-grade cervical squamous intraepithelial lesions

scientific article

A pre-existing coordinated inflammatory microenvironment is associated with complete response of vulvar high-grade squamous intraepithelial lesions to different forms of immunotherapy

scientific article published on 23 June 2020

A prospective study on the natural course of low-grade squamous intraepithelial lesions and the presence of HPV16 E2-, E6- and E7-specific T-cell responses

scientific article published on 01 January 2010

ATIM-20. GAPVAC-101 TRIAL OF A HIGHLY PERSONALIZED PEPTIDE VACCINATION FOR PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA

Activation of tumor-promoting type 2 macrophages by EGFR-targeting antibody cetuximab

scientific article

Actively personalized vaccination trial for newly diagnosed glioblastoma

scientific article published on 19 December 2018

Addition of interferon-α to the p53-SLP® vaccine results in increased production of interferon-γ in vaccinated colorectal cancer patients: a phase I/II clinical trial

scientific article published on 21 November 2012

Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer

scientific article published on 02 June 2020

Aerosol immunization with NYVAC and MVA vectored vaccines is safe, simple, and immunogenic

scholarly article

Alternative peptide repertoire of HLA-E reveals a binding motif that is strikingly similar to HLA-A2

scientific article published on 13 August 2012

An Unexpectedly Large Polyclonal Repertoire of HPV-Specific T Cells Is Poised for Action in Patients with Cervical Cancer

scientific article published on 16 March 2010

Anti-CTLA-4 therapy broadens the melanoma-reactive CD8+ T cell response.

scientific article published on September 2014

Anti-inflammatory M2 type macrophages characterize metastasized and tyrosine kinase inhibitor-treated gastrointestinal stromal tumors.

scientific article published in August 2010

Antitumor efficacy of wild-type p53-specific CD4(+) T-helper cells

scientific article published on 01 November 2002

Association of cervical cancer with the presence of CD4+ regulatory T cells specific for human papillomavirus antigens.

scholarly article

Balancing between antitumor efficacy and autoimmune pathology in T-cell-mediated targeting of carcinoembryonic antigen

scientific article published on 01 October 2008

CD163+ cytokine-producing cDC2 stimulate intratumoral type 1 T cell responses in HPV16-induced oropharyngeal cancer

scientific article published on 01 August 2020

CD39 identifies the CD4+ tumor-specific T cell population in human cancer

scientific article published on 05 August 2020

CD4+ T Cell and NK Cell Interplay Key to Regression of MHC Class Ilow Tumors upon TLR7/8 Agonist Therapy

scientific article published on 21 June 2017

CD40-mediated amplification of local immunity by epithelial cells is impaired by HPV.

scientific article

CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses

scientific article published on 26 November 2014

CD8+ CTL priming by exact peptide epitopes in incomplete Freund's adjuvant induces a vanishing CTL response, whereas long peptides induce sustained CTL reactivity

scientific article

CD8+ T cell responses against TAP-inhibited cells are readily detected in the human population

scientific article published on 27 October 2010

Cell mediated immunity against HPV16 E2, E6 and E7 peptides in women with incident CIN and in constantly HPV-negative women followed-up for 10-years

scientific article published on 20 May 2015

Characterization of antigen-specific immune responses induced by canarypox virus vaccines

scientific article

Chemically synthesized protein as tumour-specific vaccine: immunogenicity and efficacy of synthetic HPV16 E7 in the TC-1 mouse tumour model

scientific article

Chemotherapy Alters Monocyte Differentiation to Favor Generation of Cancer-Supporting M2 Macrophages in the Tumor Microenvironment ⬇️

scientific article published on February 22, 2013

Chirality of TLR-2 ligand Pam3CysSK4 in fully synthetic peptide conjugates critically influences the induction of specific CD8+ T-cells

scientific article

Circulating human papillomavirus type 16 specific T-cells are associated with HLA Class I expression on tumor cells, but not related to the amount of viral oncogene transcripts

scientific article published on 01 December 2007

Classification of current anticancer immunotherapies

scientific article

Clinical characteristics associated with development of recurrence and progression in usual-type vulvar intraepithelial neoplasia

scientific article

Colorectal cancer vaccines in clinical trials.

scientific article published on June 2011

Combining Immune Checkpoint Blockade and Tumor-Specific Vaccine for Patients With Incurable Human Papillomavirus 16-Related Cancer: A Phase 2 Clinical Trial

article

Competition-based cellular peptide binding assay for HLA class I.

scientific article published on September 2004

Competition-based cellular peptide binding assays for 13 prevalent HLA class I alleles using fluorescein-labeled synthetic peptides

scientific article published on February 2003

Consensus nomenclature for CD8(+) T cell phenotypes in cancer

scientific article published on 25 February 2015

Control of immune escaped human papilloma virus is regained after therapeutic vaccination

scientific article published on 7 March 2017

Cooperative induction of apoptosis in NRAS mutant melanoma by inhibition of MEK and ROCK.

scientific article

Correlates of immune and clinical activity of novel cancer vaccines

scientific article published on 27 April 2018

Corrigendum: High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma

scientific article published on 01 October 2016

Cryopreservation of MHC multimers: Recommendations for quality assurance in detection of antigen specific T cells

scientific article published on 8 October 2014

Data analysis as a source of variability of the HLA-peptide multimer assay: from manual gating to automated recognition of cell clusters

scientific article

De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute.

scientific article published on April 2016

Defining the critical hurdles in cancer immunotherapy

scientific article published on 14 December 2011

Demarcated thresholds of tumor-specific CD8 T cells elicited by MCMV-based vaccine vectors provide robust correlates of protection

scientific article published on 31 January 2019

Dendritic cell vaccination and CD40-agonist combination therapy licenses T cell-dependent antitumor immunity in a pancreatic carcinoma murine model

scientific article published on 01 July 2020

Dendritic cells process synthetic long peptides better than whole protein, improving antigen presentation and T-cell activation

scientific article published on 5 August 2013

Design and development of synthetic peptide vaccines: past, present and future

scientific article published on August 2007

Detection and functional analysis of CD8+ T cells specific for PRAME: a target for T-cell therapy

scientific article published in May 2006

Detection and functional assessment of regulatory T cells in clinical samples.

scientific article

Detection of human papillomavirus (HPV) 16-specific CD4+ T-cell immunity in patients with persistent HPV16-induced vulvar intraepithelial neoplasia in relation to clinical impact of imiquimod treatment

scientific article published in July 2005

Detection of human papillomavirus type 18 E6 and E7-specific CD4+ T-helper 1 immunity in relation to health versus disease

article

Development of an RNA-based kit for easy generation of TCR-engineered lymphocytes to control T-cell assay performance

scientific article published on 20 April 2018

Different Subsets of Tumor-Infiltrating Lymphocytes Correlate with Macrophage Influx and Monosomy 3 in Uveal Melanoma

scientific article published on 9 August 2012

Digital PCR-Based T-cell Quantification-Assisted Deconvolution of the Microenvironment Reveals that Activated Macrophages Drive Tumor Inflammation in Uveal Melanoma

scientific article published on 09 August 2018

Distinct regulation and impact of type 1 T-cell immunity against HPV16 L1, E2 and E6 antigens during HPV16-induced cervical infection and neoplasia

scientific article published on 01 February 2006

Distinct uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells

scientific article published on 26 April 2007

Dominant contribution of the proteasome and metalloproteinases to TAP-independent MHC-I peptide repertoire

scientific article

EGFR signaling suppresses type 1 cytokine-induced T-cell attracting chemokine secretion in head and neck cancer

scientific article published in PLoS ONE

Editorial overview: Tumour immunology: What's beyond today's success in tumor immunology

scientific article published on 20 February 2016

Effect of Productive Human Papillomavirus 16 Infection on Global Gene Expression in Cervical Epithelium

article

Effect of hypoxic stress on migration and characteristics of monocytes in uveal melanoma

scientific article published on May 2014

Effective cooperation of monoclonal antibody and peptide vaccine for the treatment of mouse melanoma

scientific article published on 30 November 2012

Effective therapeutic anticancer vaccines based on precision guiding of cytolytic T lymphocytes

scientific article published in October 2002

Efficient ex vivo induction of T cells with potent anti-tumor activity by protein antigen encapsulated in nanoparticles ⬇️

scientific article published on April 24, 2013

Enforced OX40 Stimulation Empowers Booster Vaccines to Induce Effective CD4+ and CD8+ T Cell Responses against Mouse Cytomegalovirus Infection

scientific article published on 20 February 2017

Epitope Selection for HLA-DQ2 Presentation: Implications for Celiac Disease and Viral Defense

scientific article published on 29 March 2019

Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides

scientific article published on July 2002

Evaluation of immunological cross-reactivity between clade A9 high-risk human papillomavirus types on the basis of E6-Specific CD4+ memory T cell responses

scientific article published on October 2010

Expression of coinhibitory receptors on T cells in the microenvironment of usual vulvar intraepithelial neoplasia is related to proinflammatory effector T cells and an increased recurrence-free survival

scientific article published on 15 September 2014

Features of Effective T Cell-Inducing Vaccines against Chronic Viral Infections

scientific article published on 16 February 2018

Frequent detection of human papillomavirus 16 E2-specific T-helper immunity in healthy subjects

scientific article

Frequent display of human papillomavirus type 16 E6-specific memory t-Helper cells in the healthy population as witness of previous viral encounter

article

Future Challenges in Cancer Resistance to Immunotherapy

scientific article published on 10 April 2020

Generating HPV specific T helper cells for the treatment of HPV induced malignancies using TCR gene transfer.

scientific article

Generation of TCR-engineered T cells and their use to control the performance of T cell assays

scientific article published on 8 May 2015

Generation of TCR-engineered reference cell samples to control T-cell assay performance

scientific article published on 07 June 2019

Genetic evolution of uveal melanoma guides the development of an inflammatory microenvironment

scientific article

Genetic variation of antigen processing machinery components and association with cervical carcinoma

scientific article published on 01 June 2007

Genome-wide promoter methylation analysis identifies epigenetic silencing of MAPK13 in primary cutaneous melanoma

scientific article published on 17 April 2013

HLA-E expression by gynecological cancers restrains tumor-infiltrating CD8⁺ T lymphocytes.

scientific article

HPV16 E7 DNA tattooing: safety, immunogenicity, and clinical response in patients with HPV-positive vulvar intraepithelial neoplasia.

scientific article

HPV16 synthetic long peptide (HPV16-SLP) vaccination therapy of patients with advanced or recurrent HPV16-induced gynecological carcinoma, a phase II trial

scientific article

Harmonisation of short-term in vitro culture for the expansion of antigen-specific CD8(+) T cells with detection by ELISPOT and HLA-multimer staining

scientific article

Harmonization of immune biomarker assays for clinical studies

scientific article

Harmonization of the intracellular cytokine staining assay

scientific article published on 22 May 2012

Heterogeneity revealed by integrated genomic analysis uncovers a molecular switch in malignant uveal melanoma

scientific article published on 8 October 2015

Hierarchical modeling for rare event detection and cell subset alignment across flow cytometry samples

scientific article

High Number of Intraepithelial CD8+Tumor-Infiltrating Lymphocytes Is Associated with the Absence of Lymph Node Metastases in Patients with Large Early-Stage Cervical Cancer

scientific article published on 01 January 2007

High numbers of activated helper T cells are associated with better clinical outcome in early stage vulvar cancer, irrespective of HPV or p53 status

scientific article published on 03 September 2019

High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma

scientific article published on 22 December 2014

Host genetics and tumor environment determine the functional impact of neutrophils in mouse tumor models

scientific article published on 01 September 2020

Human Immunodeficiency Virus and Human Papilloma Virus - why HPV-induced lesions do not spontaneously resolve and why therapeutic vaccination can be successful

scientific article

Human Papillomavirus Downregulates the Expression of IFITM1 and RIPK3 to Escape from IFNγ- and TNFα-Mediated Antiproliferative Effects and Necroptosis

scientific article

Human Papillomavirus Type 16-Positive Cervical Cancer Is Associated with Impaired CD4+ T-Cell Immunity against Early Antigens E2 and E6

scientific article published on 01 August 2004

Human leukocyte antigen class I, MHC class I chain-related molecule A, and CD8+/regulatory T-cell ratio: which variable determines survival of cervical cancer patients?

scientific article

Human papilloma virus specific T cells infiltrating cervical cancer and draining lymph nodes show remarkably frequent use of HLA-DQ and -DP as a restriction element.

scientific article published in February 2008

Human papillomavirus (HPV) upregulates the cellular deubiquitinase UCHL1 to suppress the keratinocyte's innate immune response

scientific article

Human papillomavirus 16 E2-, E6- and E7-specific T-cell responses in children and their mothers who developed incident cervical intraepithelial neoplasia during a 14-year follow-up of the Finnish Family HPV cohort

scientific article published on 13 February 2014

Human papillomavirus 16-specific cell-mediated immunity in children born to mothers with incident cervical intraepithelial neoplasia (CIN) and to those constantly HPV negative

scientific article

Human papillomavirus deregulates the response of a cellular network comprising of chemotactic and proinflammatory genes

scientific article

IDO and galectin-3 hamper the ex vivo generation of clinical grade tumor-specific T cells for adoptive cell therapy in metastatic melanoma

scientific article

IL-6-mediated resistance to immunotherapy is linked to impaired myeloid cell function

scientific article published on 01 September 2020

Identification and manipulation of tumor associated macrophages in human cancers ⬇️

scientific article published on December 16, 2011

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma

scientific article published on 02 August 2018

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma

scientific article published on 01 June 2019

Identification of non-mutated neoantigens presented by TAP-deficient tumors.

scientific article published on 16 August 2018

Identification, isolation, and culture of HLA-A2-specific B lymphocytes using MHC class I tetramers

scientific article published on 01 December 2003

Immune response against frameshift-induced neopeptides in HNPCC patients and healthy HNPCC mutation carriers

scientific article published on 09 July 2008

Immunization with a P53 synthetic long peptide vaccine induces P53-specific immune responses in ovarian cancer patients, a phase II trial

scientific article published in November 2009

Immunoguiding, the Final Frontier in the Immunotherapy of Cancer

Immunological responses in women with human papillomavirus type 16 (HPV-16)-associated anogenital intraepithelial neoplasia induced by heterologous prime-boost HPV-16 oncogene vaccination

scientific article published in May 2004

Immunotherapeutic Potential of TGF-β Inhibition and Oncolytic Viruses

scientific article published on 26 March 2020

Immunotherapy for persistent viral infections and associated disease ⬇️

scientific article published on January 10, 2011

Immunotherapy of Human Papilloma Virus Induced Disease ⬇️

scientific article published on December 28, 2012

Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines

scientific article published on May 2008

Improved peptide vaccine strategies, creating synthetic artificial infections to maximize immune efficacy

scientific article published on 12 August 2006

Induction of Tumor-Specific CD4+ and CD8+ T-Cell Immunity in Cervical Cancer Patients by a Human Papillomavirus Type 16 E6 and E7 Long Peptides Vaccine

scientific article published on 01 January 2008

Induction of p53-specific immune responses in colorectal cancer patients receiving a recombinant ALVAC-p53 candidate vaccine

scientific article published on 01 May 2002

Induction of p53-specific immunity by a p53 synthetic long peptide vaccine in patients treated for metastatic colorectal cancer

scientific article published on 01 February 2009

Influenza matrix 1-specific human CD4+ FOXP3+ and FOXP3(-) regulatory T cells can be detected long after viral clearance

scientific article published on 06 September 2010

Inhibition of CSF-1R supports T-cell mediated melanoma therapy

scientific article

Interleukin-6/interleukin-6 receptor pathway as a new therapy target in epithelial ovarian cancer.

scientific article published on January 2012

Intradermal delivery of TLR agonists in a human explant skin model: preferential activation of migratory dendritic cells by polyribosinic-polyribocytidylic acid and peptidoglycans.

scientific article published on 6 March 2013

Intraepithelial macrophage infiltration is related to a high number of regulatory T cells and promotes a progressive course of HPV-induced vulvar neoplasia

scientific article published on 15 September 2014

Intratumoral HPV16-specific T-cells constitute a type 1 oriented tumor microenvironment to improve survival in HPV16-driven oropharyngeal cancer

scientific article published on 10 October 2017

Lack of myeloid cell infiltration as an acquired resistance strategy to immunotherapy

scientific article published on 01 September 2020

Local and systemic XAGE-1b-specific immunity in patients with lung adenocarcinoma

scientific article

Long-term HPV-specific immune response after one versus two and three doses of bivalent HPV vaccination in Dutch girls

scientific article published on 28 September 2019

Long-term Survival and Clinical Benefit from Adoptive T-cell Transfer in Stage IV Melanoma Patients Is Determined by a Four-Parameter Tumor Immune Signature.

scientific article published on 10 January 2017

Long-term clinical and immunological effects of p53-SLP® vaccine in patients with ovarian cancer

scientific article published on 09 May 2011

Loss of BAP1 Is Associated with Upregulation of the NFkB Pathway and Increased HLA Class I Expression in Uveal Melanoma

scientific article published on 02 August 2019

Low-dose interferon-alpha preconditioning and adoptive cell therapy in patients with metastatic melanoma refractory to standard (immune) therapies: a phase I/II study

scientific article published on 01 March 2020

M2 macrophages induced by prostaglandin E2 and IL-6 from cervical carcinoma are switched to activated M1 macrophages by CD4+ Th1 cells

scientific article published on 27 June 2011

Magnitude and polarization of P53-specific T-helper immunity in connection to leukocyte infiltration of colorectal tumors.

scientific article

Managing Multi-center Flow Cytometry Data for Immune Monitoring

scientific article

Mechanisms of peptide vaccination in mouse models: tolerance, immunity, and hyperreactivity

scientific article published on January 2012

Metabolic stress in cancer cells induces immune escape through a PI3K-dependent blockade of IFNγ receptor signaling.

scientific article published on 13 June 2019

Monalizumab: inhibiting the novel immune checkpoint NKG2A

scientific article published on 17 October 2019

Monitoring of the Immune Dysfunction in Cancer Patients

scientific article

Monitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry

scientific article published on 28 June 2015

Multiple CD4 and CD8 T-cell activation parameters predict vaccine efficacy in vivo mediated by individual DC-activating agonists

scientific article published on 7 November 2006

NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines

scientific article published on 29 November 2018

Near-genomewide RNAi screening for regulators of BRAF(V600E) -induced senescence identifies RASEF, a gene epigenetically silenced in melanoma

scientific article published on 14 May 2014

Neoantigen landscape dynamics during human melanoma-T cell interactions

scientific article published on 27 June 2016

Neoantigen-specific immunity in low mutation burden colorectal cancers of the consensus molecular subtype 4

scientific article published on 30 December 2019

New approaches in vaccine-based immunotherapy for human papillomavirus-induced cancer.

scientific article published on 19 May 2015

New role of signal peptide peptidase to liberate C-terminal peptides for MHC class I presentation

scientific article published on 18 September 2013

P53-specific T cell responses in patients with malignant and benign ovarian tumors: implications for p53 based immunotherapy

scientific article published in August 2007

Peptide transporter TAP mediates between competing antigen sources generating distinct surface MHC class I peptide repertoires

scientific article

Peptide vaccination after T-cell transfer causes massive clonal expansion, tumor eradication, and manageable cytokine storm

scientific article published on 12 October 2010

Phase I Immunotherapeutic Trial with Long Peptides Spanning the E6 and E7 Sequences of High-Risk Human Papillomavirus 16 in End-Stage Cervical Cancer Patients Shows Low Toxicity and Robust Immunogenicity

article

Phase I/II study protocol to assess safety and efficacy of adoptive cell therapy with anti-PD-1 plus low-dose pegylated-interferon-alpha in patients with metastatic melanoma refractory to standard of care treatments: the ACTME trial

scientific article published on 24 November 2020

Potential use of lymph node-derived HPV-specific T cells for adoptive cell therapy of cervical cancer

scientific article published on 12 September 2016

Potentiation of a p53-SLP vaccine by cyclophosphamide in ovarian cancer: a single-arm phase II study

scientific article published on 31 January 2012

Pre-existing inflammatory immune microenvironment predicts the clinical response of vulvar high-grade squamous intraepithelial lesions to therapeutic HPV16 vaccination

scientific article published on 01 March 2020

Preconditioning of the tumor microenvironment with oncolytic reovirus converts CD3-bispecific antibody treatment into effective immunotherapy

scientific article published on 01 October 2020

Prediction of the immunogenic potential of frameshift-mutated antigens in microsatellite instable cancer

scientific article published in August 2008

Prognostic value of tumor-infiltrating dendritic cells in colorectal cancer: role of maturation status and intratumoral localization

scientific article published on 01 April 2005

Prospects of combinatorial synthetic peptide vaccine-based immunotherapy against cancer

scientific article published on April 2013

Publisher Correction: Actively personalized vaccination trial for newly diagnosed glioblastoma

scientific article published on 01 February 2019

Rapid enrichment of human papillomavirus (HPV)-specific polyclonal T cell populations for adoptive immunotherapy of cervical cancer.

scientific article published on March 2005

Rationally combining immunotherapies to improve efficacy of immune checkpoint blockade in solid tumors

scientific article

Recent progress in peptide vaccination in cancer with a focus on non-small-cell lung cancer

scientific article

Recommendations from the iSBTc-SITC/FDA/NCI Workshop on Immunotherapy Biomarkers

scientific article

Regulatory T Cell Depletion Using a CRISPR Fc-Optimized CD25 Antibody

scholarly article

Safety of intravenous administration of a canarypox virus encoding the human wild-type p53 gene in colorectal cancer patients

scientific article published on July 2003

Self-tolerance does not restrict the CD4+ T-helper response against the p53 tumor antigen

scientific article published on 01 February 2008

Serum-free freezing media support high cell quality and excellent ELISPOT assay performance across a wide variety of different assay protocols.

scientific article published on 9 November 2012

Simplified monopalmitoyl Toll-like receptor 2 ligand mini-UPam for self-adjuvanting neoantigen-based synthetic cancer vaccines

scientific article published on 12 November 2020

Skin reactions to human papillomavirus (HPV) 16 specific antigens intradermally injected in healthy subjects and patients with cervical neoplasia

scientific article published on 01 July 2008

Spontaneous tumor rejection by cbl-b-deficient CD8+ T cells

scientific article

Standard radiotherapy but not chemotherapy impairs systemic immunity in non-small cell lung cancer.

scientific article

Strong vaccine responses during chemotherapy are associated with prolonged cancer survival

scientific article published on 01 March 2020

Success or failure of vaccination for HPV16-positive vulvar lesions correlates with kinetics and phenotype of induced T-cell responses

scientific article

Successful treatment of metastatic melanoma by adoptive transfer of blood-derived polyclonal tumor-specific CD4+ and CD8+ T cells in combination with low-dose interferon-alpha

scientific article

Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation

scientific article

Surgery followed by Persistence of High-Grade Squamous Intraepithelial Lesions Is Associated with the Induction of a Dysfunctional HPV16-Specific T-Cell Response

scientific article published on 01 November 2008

Synergy between chemotherapy and cancer vaccination

scientific article published on June 2015

Synergy of therapeutic vaccination against HPV16 oncogenic proteins and standard chemotherapeutics.

scientific article published on 6 November 2014

Synthesis of 2-alkoxy-8-hydroxyadenylpeptides: towards synthetic epitope-based vaccines

scientific article published on 11 April 2006

T Cells Engaging the Conserved MHC Class Ib Molecule Qa-1b with TAP-Independent Peptides Are Semi-Invariant Lymphocytes

scientific article published on 25 January 2018

T cells specific for a TAP-independent self-peptide remain naïve in tumor-bearing mice and are fully exploitable for therapy

scientific article published on 20 November 2017

T-regulatory cells in tumour-specific vaccination strategies

scientific article published on 01 September 2008

TAP-independent self-peptides enhance T cell recognition of immune-escaped tumors

scientific article published on 19 January 2016

TEIPP peptides: exploration of unTAPped cancer antigens

scientific article published on 13 May 2019

Targeting of the Cancer-Associated Fibroblast-T-Cell Axis in Solid Malignancies

scientific article published on 15 November 2019

Targeting of the MAPK and AKT pathways in conjunctival melanoma shows potential synergy

scientific article published on 22 July 2016

The Anatomical Location Shapes the Immune Infiltrate in Tumors of Same Etiology and Affects Survival

scientific article published on 17 September 2018

The Breadth of Synthetic Long Peptide Vaccine-Induced CD8+ T Cell Responses Determines the Efficacy against Mouse Cytomegalovirus Infection.

scientific article

The NKG2A - HLA-E axis as a novel checkpoint in the tumor microenvironment

scientific article published on 14 May 2020

The Potential and Challenges of Exploiting the Vast But Dynamic Neoepitope Landscape for Immunotherapy

scientific article published on 11 September 2017

The detection of circulating human papillomavirus-specific T cells is associated with improved survival of patients with deeply infiltrating tumors

scientific article published on 05 April 2010

The development of standard samples with a defined number of antigen-specific T cells to harmonize T cell assays: a proof-of-principle study

scientific article

The immune microenvironment in vulvar (pre)cancer: review of literature and implications for immunotherapy

scientific article published on 02 November 2018

The importance of correctly timing cancer immunotherapy

scientific article published on November 2016

The interferon-related developmental regulator 1 is used by human papillomavirus to suppress NFκB activation.

scientific article

The long-term immune response after HPV16 peptide vaccination in women with low-grade pre-malignant disorders of the uterine cervix: a placebo-controlled phase II study

scientific article published on 15 November 2013

The need for improvement of the treatment of advanced and metastatic cervical cancer, the rationale for combined chemo-immunotherapy

scientific article published on February 2014

The nonpolymorphic MHC Qa-1b mediates CD8+ T cell surveillance of antigen-processing defects

scientific journal article

The nonpolymorphic MHC Qa-1b mediates CD8+ T cell surveillance of antigen-processing defects

scientific article

The positive prognostic effect of stromal CD8+ tumor-infiltrating T cells is restrained by the expression of HLA-E in non-small cell lung carcinoma

scientific article published on 7 December 2015

The role of the reporting framework MIATA within current efforts to advance immune monitoring

scholarly article by Sylvia Janetzki et al published July 2014 in Journal of Immunological Methods

The simultaneous ex vivo detection of low-frequency antigen-specific CD4+ and CD8+ T-cell responses using overlapping peptide pools.

scientific article

The status of HPV16-specific T-cell reactivity in health and disease as a guide to HPV vaccine development

scientific article

The tumor area occupied by Tbet+ cells in deeply invading cervical cancer predicts clinical outcome

scientific article

Therapeutic Peptide Vaccine-Induced CD8 T Cells Strongly Modulate Intratumoral Macrophages Required for Tumor Regression.

scientific article published on 17 April 2015

Therapeutic cancer vaccines

scientific article published on 27 July 2015

Therapeutic vaccination against human papilloma virus induced malignancies ⬇️

scientific article published on January 13, 2011

Therapeutic vaccines in cancer: moving from immunomonitoring to immunoguiding

scientific article published on 01 February 2008

Therapy of human papillomavirus-related disease

scientific article

Tissue-Specific Gene Expression during Productive Human Papillomavirus 16 Infection of Cervical, Foreskin, and Tonsil Epithelium

scientific article published on 13 August 2019

Toward harmonized phenotyping of human myeloid-derived suppressor cells by flow cytometry: results from an interim study

scientific article published on 4 January 2016

Treatment failure in patients with HPV 16-induced vulvar intraepithelial neoplasia: understanding different clinical responses to immunotherapy.

scientific article published on July 2012

Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8+ T Cells

scientific article published on 28 August 2016

Tumor mutational load, CD8+ T cells, expression of PD-L1 and HLA class I to guide immunotherapy decisions in NSCLC patients

scientific article published on 12 February 2020

Tumor-Expressed B7-H1 and B7-DC in Relation to PD-1+ T-Cell Infiltration and Survival of Patients with Cervical Carcinoma

scientific article published on 13 October 2009

Tumor-infiltrating cytotoxic T lymphocytes as independent prognostic factor in epithelial ovarian cancer with wilms tumor protein 1 overexpression

scientific article

Tumor-specific regulatory T cells in cancer patients

scientific article published on 28 March 2008

Uveal Versus Cutaneous Melanoma; Same Origin, Very Distinct Tumor Types

scientific article published on 19 June 2019

Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia

scientific article published on November 2009

Vaccination against Oncoproteins of HPV16 for Noninvasive Vulvar/Vaginal Lesions: Lesion Clearance Is Related to the Strength of the T-Cell Response.

scientific article published on 26 January 2016

Vaccination during myeloid cell depletion by cancer chemotherapy fosters robust T cell responses

scientific article

Vaccination for treatment and prevention of cancer in animal models.

scientific article

Vaccine-induced tumor necrosis factor-producing T cells synergize with cisplatin to promote tumor cell death

scientific article published on 12 December 2014

Vaccines for established cancer: overcoming the challenges posed by immune evasion

scientific article published on 11 March 2016

Vaccinia-expressed human papillomavirus 16 and 18 e6 and e7 as a therapeutic vaccination for vulval and vaginal intraepithelial neoplasia ⬇️

scientific article published on November 1, 2003

Vulvar cancer subclassification by HPV and p53 status results in three clinically distinct subtypes

scientific article published on 21 September 2020

Withdrawal: Identification of tumor antigens among the HLA peptidomes of glioblastoma tumors and plasma

scientific article published on 01 June 2019

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