List of works - William Louch

3D dSTORM imaging reveals novel detail of ryanodine receptor localization in rat cardiac myocytes

scientific article published on 28 November 2018

A horse of a different colour: distinct mechanisms of HFpEF and HFrEF

scientific article published on 28 September 2020

Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase alpha2-isoform in heart failure

scientific article

An analysis of deformation-dependent electromechanical coupling in the mouse heart

scientific article published on 21 May 2012

Beta-adrenergic stimulation maintains cardiac function in Serca2 knockout mice

scientific article published on 19 March 2013

Ca(2+) wave probability is determined by the balance between SERCA2-dependent Ca(2+) reuptake and threshold SR Ca(2+) content.

scientific article published on 17 January 2011

Cardiomyocyte substructure reverts to an immature phenotype during heart failure

Channel surfing: new insights into plasticity of excitation-contraction coupling

article

Control of Ca2+ release by action potential configuration in normal and failing murine cardiomyocytes

scientific article

Elevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasis

scientific article

Human Heart Organoid-derived Extracellular Vesicles for Cardiac Intercellular Communication

scientific article published on 12 September 2023

Hypokalemia Promotes Arrhythmia by Distinct Mechanisms in Atrial and Ventricular Myocytes

scientific article published on 19 February 2020

I(CaL) inhibition prevents arrhythmogenic Ca(2+) waves caused by abnormal Ca(2+) sensitivity of RyR or SR Ca(2+) accumulation

scientific article published on 14 February 2013

Increased cardiomyocyte function and Ca2+ transients in mice during early congestive heart failure

scientific article published on 17 May 2007

Increased passive stiffness promotes diastolic dysfunction despite improved Ca2+ handling during left ventricular concentric hypertrophy.

scientific article published in August 2017

Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload

scientific article

Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models

scientific article

Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene

scientific article

NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture

scientific article published on January 2017

Nanoscale organization of ryanodine receptor distribution and phosphorylation pattern determines the dynamics of calcium sparks

scientific article published on 06 June 2022

No rest for the weary: diastolic calcium homeostasis in the normal and failing myocardium

scientific article published on October 2012

Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes

scientific article published on 17 December 2009

Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression

article

Reply from M. Frisk, D. B. Lipsett and W. E. Louch

scientific article published on 12 May 2019

Ryanodine receptor dispersion disrupts Ca release in failing cardiac myocytes

scientific article

Slow Ca²⁺ sparks de-synchronize Ca²⁺ release in failing cardiomyocytes: evidence for altered configuration of Ca²⁺ release units?

scientific article published on 30 January 2013

Slow contractions characterize failing rat hearts

scientific article published on 17 March 2008

Slowing of cardiomyocyte Ca2+ release and contraction during heart failure progression in postinfarction mice

scientific article published on 6 February 2009

Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout

scientific article published on 14 December 2009

Synchrony of cardiomyocyte Ca(2+) release is controlled by T-tubule organization, SR Ca(2+) content, and ryanodine receptor Ca(2+) sensitivity

scientific article published on April 2013

T-tubule disorganization and reduced synchrony of Ca2+ release in murine cardiomyocytes following myocardial infarction

scientific article published on 18 May 2006

List of works by William Louch

3D dSTORM imaging reveals novel detail of ryanodine receptor localization in rat cardiac myocytes

A horse of a different colour: distinct mechanisms of HFpEF and HFrEF

Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase alpha2-isoform in heart failure

An analysis of deformation-dependent electromechanical coupling in the mouse heart

Beta-adrenergic stimulation maintains cardiac function in Serca2 knockout mice

Ca(2+) wave probability is determined by the balance between SERCA2-dependent Ca(2+) reuptake and threshold SR Ca(2+) content.

Cardiomyocyte substructure reverts to an immature phenotype during heart failure

Channel surfing: new insights into plasticity of excitation-contraction coupling

Control of Ca2+ release by action potential configuration in normal and failing murine cardiomyocytes

Elevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasis

Human Heart Organoid-derived Extracellular Vesicles for Cardiac Intercellular Communication

Hypokalemia Promotes Arrhythmia by Distinct Mechanisms in Atrial and Ventricular Myocytes

I(CaL) inhibition prevents arrhythmogenic Ca(2+) waves caused by abnormal Ca(2+) sensitivity of RyR or SR Ca(2+) accumulation

Increased cardiomyocyte function and Ca2+ transients in mice during early congestive heart failure

Increased passive stiffness promotes diastolic dysfunction despite improved Ca2+ handling during left ventricular concentric hypertrophy.

Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload

Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models

Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene

NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture

Nanoscale organization of ryanodine receptor distribution and phosphorylation pattern determines the dynamics of calcium sparks

No rest for the weary: diastolic calcium homeostasis in the normal and failing myocardium

Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes

Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression

Reply from M. Frisk, D. B. Lipsett and W. E. Louch

Ryanodine receptor dispersion disrupts Ca release in failing cardiac myocytes

Slow Ca²⁺ sparks de-synchronize Ca²⁺ release in failing cardiomyocytes: evidence for altered configuration of Ca²⁺ release units?

Slow contractions characterize failing rat hearts

Slowing of cardiomyocyte Ca2+ release and contraction during heart failure progression in postinfarction mice

Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout

Synchrony of cardiomyocyte Ca(2+) release is controlled by T-tubule organization, SR Ca(2+) content, and ryanodine receptor Ca(2+) sensitivity

T-tubule disorganization and reduced synchrony of Ca2+ release in murine cardiomyocytes following myocardial infarction