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List of works by Lynn M. Corcoran

A Myc-dependent division timer complements a cell-death timer to regulate T cell and B cell responses

scientific article published on 7 November 2016

Activation of the c-myc oncogene in B and T lymphoid tumors.

scientific article

All known in vivo functions of the Oct-2 transcription factor require the C-terminal protein domain

scientific journal article

Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis

scientific article published on 14 January 2020

B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1

scientific article

BTB-ZF transcription factors, a growing family of regulators of early and late B-cell development

scientific article published on 18 March 2014

Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

scientific journal article

Bcl-2 expression promotes B- but not T-lymphoid development in scid mice

scientific journal article

Blimp1 is limiting for transformation in a mouse plasmacytoma model

scientific article published on 27 March 2009

CD36 Is Differentially Expressed by CD8+ Splenic Dendritic Cells But Is Not Required for Cross-Presentation In Vivo

scientific article published on 01 June 2002

CD93 is required for maintenance of antibody secretion and persistence of plasma cells in the bone marrow niche

scientific article

Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas

scientific article

Class-Switch Recombination Occurs Infrequently in Germinal Centers

scientific article published on 30 July 2019

Continued differentiation during B lymphopoiesis requires signals in addition to cell survival

article

Convergent differentiation: myeloid and lymphoid pathways to murine plasmacytoid dendritic cells

scientific article published on 10 October 2012

Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells.

scientific article published in December 2007

Defined blocks in terminal plasma cell differentiation of common variable immunodeficiency patients

scientific article published in October 2005

Development of murine plasmacytoid dendritic cell subsets.

scientific article

Different kinetics of blimp-1 induction in B cell subsets revealed by reporter gene.

scientific article

Differential regulation of CD36 expression in antigen-presenting cells: Oct-2 dependence in B lymphocytes but not dendritic cells or macrophages

scientific article published on 01 October 2002

Differential requirement for OBF-1 during antibody-secreting cell differentiation

scientific article

Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development.

scientific article published on 23 May 2016

Enhanced cell survival and tumorigenesis.

scientific article

Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation

scientific journal article

Expression of a bcl-2 transgene reduces proliferation and slows turnover of developing B lymphocytes in vivo

Fas ligand-mediated immune surveillance by T cells is essential for the control of spontaneous B cell lymphomas

scientific article published on 2 February 2014

Generation of novel Id2 and E2-2, E2A and HEB antibodies reveals novel Id2 binding partners and species-specific expression of E-proteins in NK cells

scientific article published on 23 August 2018

Germinal center-independent, IgM-mediated autoimmunity in sanroque mice lacking Obf1.

scientific article published on 12 November 2013

Germline-activating mutations in PIK3CD compromise B cell development and function

scientific article published on 17 July 2018

Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans

article

High Rate of Antibody Secretion Is not Integral to Plasma Cell Differentiation as Revealed by XBP-1 Deficiency

scientific article published on 27 August 2012

High-affinity B cell receptor ligation by cognate antigen induces cytokine-independent isotype switching.

scientific article published on 14 May 2010

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism

scientific article

IL4 and IL21 cooperate to induce the high Bcl6 protein level required for germinal center formation.

scientific article

Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia

scientific article published on 30 June 2016

Identification of Pax5 target genes in early B cell differentiation

scientific article published in February 2008

Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage

scientific article published in April 2005

Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1.

scientific article published in May 2007

Long-Lived Plasma Cells Have a Sweet Tooth

scientific article published in July 2016

Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins

scientific article published on 24 July 2018

Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells

scientific journal article

Murine T lymphomas in which the cellular myc oncogene has been activated by retroviral insertion

scientific article published in May 1984

NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells

scientific article published on 28 March 2016

Normalization of boutique two-color microarrays with a high proportion of differentially expressed probes

scientific article published on January 2007

Oct2 and Obf1 as Facilitators of B:T Cell Collaboration during a Humoral Immune Response

scientific article

Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor alpha chain expression on activated B cells.

scientific article published on 4 February 2008

PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia

scientific article published on 02 March 2016

Plasma cell development and survival.

scientific article published on September 2010

Plasma cell ontogeny defined by quantitative changes in blimp-1 expression

scientific article

RUNX2 Mediates Plasmacytoid Dendritic Cell Egress from the Bone Marrow and Controls Viral Immunity.

scientific article published on 13 April 2016

Regulation of germinal center responses, memory B cells and plasma cell formation-an update

scientific article

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses

scientific article

Repression of Flt3 by Pax5 is crucial for B-cell lineage commitment

scientific journal article

Silencing and nuclear repositioning of the lambda5 gene locus at the pre-B cell stage requires Aiolos and OBF-1.

scientific article

The BTB-ZF transcription factor Zbtb20 is driven by Irf4 to promote plasma cell differentiation and longevity

scientific article

The Ets factor Spi-B is a direct critical target of the coactivator OBF-1

scholarly article

The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15.

scientific article published on 9 January 2016

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

scientific article published in Nature

The flavors of plasma cells.

scientific article published on 28 June 2015

The generation of antibody-secreting plasma cells.

scientific article

The genetic network controlling plasma cell differentiation

scientific article published on September 15, 2011

The lymphoid past of mouse plasmacytoid cells and thymic dendritic cells

scientific article published on 01 May 2003

The myc oncogene and lymphoid neoplasia: from translocations to transgenic mice

The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation

scientific article

Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT

scientific article published on 02 January 2019

Transcription factor IRF4 regulates germinal center cell formation through a B cell-intrinsic mechanism

scientific article published on 3 March 2014

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells.

scientific article published on 20 April 2015

Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance

scientific article published on 26 March 2006

Transposition of the immunoglobulin heavy chain enhancer to the myc oncogene in a murine plasmacytoma

scientific article published in January 1985

Variant (6;15) translocations in murine plasmacytomas involve a chromosome 15 locus at least 72 kb from the c-myc oncogene

scientific article

c-myc-induced lymphomagenesis in transgenic mice and the role of the Pvt-1 locus in lymphoid neoplasia

scientific article